Nicolas L. Young, Ph.D.

Affiliations: 
2016- Biochemistry Baylor College of Medicine, Houston, TX 
Area:
Analytical Chemistry, Mass Spectrometry, Epigenetics
Website:
https://www.bcm.edu/research/labs/nicolas-young
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"Nicolas Young"
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Parents

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Carlito B. Lebrilla grad student 2007 UC Davis
 (Nanoflow liquid chromatography Fourier transform mass spectrometry: Applications in elucidating protein oxidation and improvements in analytical specificity and mass accuracy.)
Benjamin Garcia post-doc 2008-2012 Princeton (Chemistry Tree)
Alan G. Marshall research scientist 2012-2015 Florida State (Chemistry Tree)
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Publications

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Poncha KF, Paparella AT, Young NL. (2025) Unraveling Posttranslational Modification Complexity: Advances in Quantitative Histone Proteoform Mass Spectrometry. Mass Spectrometry Reviews
Poncha KF, Paparella AT, Young NL. (2025) Normalized and Directional Interplay Scoring for the Interrogation of Proteoform Data. Journal of Proteome Research
Poncha KF, Paparella AT, Young NL. (2024) Normalized and Directional Interplay Scoring for the Interrogation of Proteoform Data. Biorxiv : the Preprint Server For Biology
Fox GC, Poncha KF, Smith BR, et al. (2024) Histone H3K18 & H3K23 acetylation directs establishment of MLL-mediated H3K4 methylation. The Journal of Biological Chemistry. 107527
Fox GC, Poncha KF, Smith BR, et al. (2024) H3K18 & H3K23 acetylation directs establishment of MLL-mediated H3K4 methylation. Biorxiv : the Preprint Server For Biology
Phillips M, Malone KL, Boyle BW, et al. (2024) Impact of Combinatorial Histone Modifications on Acetyllysine Recognition by the ATAD2 and ATAD2B Bromodomains. Journal of Medicinal Chemistry
Taylor BC, Steinthal LH, Dias M, et al. (2024) Histone proteoform analysis reveals epigenetic changes in adult mouse brown adipose tissue in response to cold stress. Biorxiv : the Preprint Server For Biology
Jain K, Marunde MR, Burg JM, et al. (2023) An acetylation-mediated chromatin switch governs H3K4 methylation read-write capability. Elife. 12
Taylor BC, Young NL. (2023) Histone H4 proteoforms and post-translational modifications in the Mus musculus brain with quantitative comparison of ages and brain regions. Analytical and Bioanalytical Chemistry. 415: 1627-1639
Wang X, Shi Z, Lu HY, et al. (2022) High-throughput profiling of histone post-translational modifications and chromatin modifying proteins by reverse phase protein array. Journal of Proteomics. 104596
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