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Raymond D. Meng, Ph.D.

Affiliations: 
2001 University of Pennsylvania, Philadelphia, PA, United States 
Area:
Molecular Biology, Oncology
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Wafik S. El-Deiry grad student 2001 Penn
 (The TRAIL decoy receptor TRUNDD ( DcR2, TRAIL-R4) is induced by adenovirus-p53 overexpression and can delay TRAIL-, p53-, and KILLER/ DR5-dependent colon cancer apoptosis.)

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Meng RD, Shelton CC, Li YM, et al. (2009) gamma-Secretase inhibitors abrogate oxaliplatin-induced activation of the Notch-1 signaling pathway in colon cancer cells resulting in enhanced chemosensitivity. Cancer Research. 69: 573-82
McGarvey TW, Meng RD, Johnson O, et al. (2001) Growth inhibitory effect of p21 and p53 containing adenoviruses on transitional cell carcinoma cell lines in vitro and in vivo. Urologic Oncology. 6: 155-162
Meng RD, El-Deiry WS. (2001) p53-independent upregulation of KILLER/DR5 TRAIL receptor expression by glucocorticoids and interferon-gamma. Experimental Cell Research. 262: 154-69
McGarvey TW, Meng RD, Johnson O, et al. (2001) Growth inhibitory effect of p21 and p53 containing adenoviruses on transitional cell carcinoma cell lines in vitro and in vivo Urologic Oncology. 6: 155-162
Meng RD, McDonald ER, Sheikh MS, et al. (2000) The TRAIL Decoy Receptor TRUNDD (DcR2, TRAIL-R4) Is Induced by Adenovirus-p53 Overexpression and Can Delay TRAIL-, p53-, and KILLER/DR5-Dependent Colon Cancer Apoptosis Molecular Therapy. 1: 130-144
Wu GS, Burns TF, McDonald ER, et al. (1999) Induction of the TRAIL receptor KILLER/DR5 in p53-dependent apoptosis but not growth arrest. Oncogene. 18: 6411-8
Song S, MacLachlan TK, Meng RD, et al. (1999) Comparative gene expression profiling in response to p53 in a human lung cancer cell line. Biochemical and Biophysical Research Communications. 264: 891-5
Maclachlan TK, Meng RD, El-Deiry WS. (1999) "p53: Twenty Years On" in Trieste, Italy, May 20-22, 1999. Journal of Cellular Physiology. 181: 371-4
Meng RD, Phillips P, El-Deiry WS. (1999) p53-independent increase in E2F-1 expression enhances the cytotoxic effects of etoposide and of adriamycin. International Journal of Oncology. 14: 5-14
Meng RD, El-Deiry WS. (1998) Tumor suppressor gene therapy for cancer: from the bench to the clinic. Drug Resistance Updates : Reviews and Commentaries in Antimicrobial and Anticancer Chemotherapy. 1: 205-10
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