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Ireena Bagai, Ph.D.

Affiliations: 
2008 Biochemistry University of Arizona, Tucson, AZ 
Area:
Biochemistry, General Biophysics
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Parents

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Megan M. McEvoy grad student 2008 University of Arizona
 (Not just a passive adaptor, the periplasmic component CusB of Escherichia coli's CusCFBA copper efflux system has an active functional role.)
Stephen W. Ragsdale post-doc 2010-2012 The University of Michigan Medical School (Chemistry Tree)

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Publications

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Davydov R, Fleischhacker AS, Bagai I, et al. (2015) Comparison of the Mechanisms of Heme Hydroxylation by Heme Oxygenases-1 and -2: Kinetic and Cryoreduction Studies. Biochemistry
Fleischhacker AS, Sharma A, Choi M, et al. (2015) The C-terminal heme regulatory motifs of heme oxygenase-2 are redox-regulated heme binding sites. Biochemistry. 54: 2709-18
Bagai I, Sarangi R, Fleischhacker AS, et al. (2015) Spectroscopic studies reveal that the heme regulatory motifs of heme oxygenase-2 are dynamically disordered and exhibit redox-dependent interaction with heme. Biochemistry. 54: 2693-708
Spencer AL, Bagai I, Becker DF, et al. (2014) Protein/protein interactions in the mammalian heme degradation pathway: heme oxygenase-2, cytochrome P450 reductase, and biliverdin reductase. The Journal of Biological Chemistry. 289: 29836-58
Zuiderweg ER, Bagai I, Rossi P, et al. (2013) EZ-ASSIGN, a program for exhaustive NMR chemical shift assignments of large proteins from complete or incomplete triple-resonance data. Journal of Biomolecular Nmr. 57: 179-91
Mealman TD, Bagai I, Singh P, et al. (2011) Interactions between CusF and CusB identified by NMR spectroscopy and chemical cross-linking coupled to mass spectrometry. Biochemistry. 50: 2559-66
Bagai I, Ragsdale SW, Zuiderweg ER. (2011) Pseudo-4D triple resonance experiments to resolve HN overlap in the backbone assignment of unfolded proteins. Journal of Biomolecular Nmr. 49: 69-74
Bagai I, Rensing C, Blackburn NJ, et al. (2008) Direct metal transfer between periplasmic proteins identifies a bacterial copper chaperone. Biochemistry. 47: 11408-14
Bagai I, Liu W, Rensing C, et al. (2007) Substrate-linked conformational change in the periplasmic component of a Cu(I)/Ag(I) efflux system. The Journal of Biological Chemistry. 282: 35695-702
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