Svetlana B. Tikunova, Ph.D.
Affiliations: | 2000 | Ohio State University, Columbus, Columbus, OH |
Area:
General Biophysics, General ChemistryGoogle:
"Svetlana Tikunova"Mean distance: (not calculated yet)
Parents
Sign in to add mentor| Ruth A. Altschuld | grad student | 2000 | Ohio State | |
| (Studies of calcium and magnesium binding and exchange with mutants of troponin C and calmodulin and characterizing the interactions of calmodulin with TRP calcium channels.) | ||||
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Publications
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| Tikunova SB, Thuma J, Davis JP. (2023) Mouse Models of Cardiomyopathies Caused by Mutations in Troponin C. International Journal of Molecular Sciences. 24 |
| Williams RB, Alam Afsar MN, Tikunova S, et al. (2023) Human disease-associated calmodulin mutations alter calcineurin function through multiple mechanisms. Cell Calcium. 113: 102752 |
| Hantz ER, Tikunova SB, Belevych N, et al. (2023) Targeting Troponin C with Small Molecules Containing Diphenyl Moieties: Calcium Sensitivity Effects on Striated Muscles and Structure-Activity Relationship. Journal of Chemical Information and Modeling |
| Hantz ER, Tikunova SB, Belevych N, et al. (2023) Targeting Troponin C with Small Molecules Containing Diphenyl Moieties: Calcium Sensitivity Effects on Striated Muscle and Structure Activity Relationship. Biorxiv : the Preprint Server For Biology |
| Mahmud Z, Tikunova S, Belevych N, et al. (2022) Small Molecule RPI-194 Stabilizes Activated Troponin to Increase the Calcium Sensitivity of Striated Muscle Contraction. Frontiers in Physiology. 13: 892979 |
| Coldren WH, Tikunova SB, Davis JP, et al. (2020) Discovery of Novel Small-Molecule Calcium Sensitizers for Cardiac Troponin C: A Combined Virtual and Experimental Screening Approach. Journal of Chemical Information and Modeling |
| Bogdanov V, Tikunova S, Kou Y, et al. (2020) In Silico Engineering of Calmodulin to Bind the Cardiac Ryanodine Receptor with High Affinity Biophysical Journal. 118: 594a |
| Hauck GT, Kou Y, Tikunova S, et al. (2020) Mathematical Modeling of Calcium Binding to Human, Plant, and Engineered Calmodulin, as well as Cardiac and Slow Skeletal Troponin Biophysical Journal. 118 |
| Sun B, Vaughan DM, Tikunova SB, et al. (2019) Calmodulin/Calcineurin Interaction Beyond the Calmodulin-binding Region Contributes to Calcineurin Activation. Biochemistry |
| Bowman J, Aprahamian M, Tikunova S, et al. (2019) Virtual Screening Finds Troponin Calcium Sensitizers and Umbrella Sampling Simulations Elucidate Differences in Troponin C Isoform and Mutant Hydrophobic Patch Exposure Biophysical Journal. 116: 435a |