Sean C. Gifford, Ph.D.

Affiliations: 
2006 Boston University, Boston, MA, United States 
Area:
Biomedical Engineering, Cell Biology
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Mark Bitensky grad student 2006 Boston University
 (Applications of microfabrication technology and in vivo cell labeling in the study of erythrocyte senescence.)
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Publications

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Mukhamedshin A, Reddington RC, Dinh MTP, et al. (2023) Rapid, label-free enrichment of lymphocytes in a closed system using a flow-through microfluidic device. Bioengineering & Translational Medicine. 9: e10602
Abhishek K, Louis Sam Titus ASC, Dinh MTP, et al. (2023) Red blood cell rosetting enables size-based separation of specific lymphocyte subsets from blood in a microfluidic device. Lab On a Chip
Strachan BC, Xia H, Vörös E, et al. (2019) Improved expansion of T cells in culture when isolated with an equipment-free, high-throughput, flow-through microfluidic module versus traditional density gradient centrifugation. Cytotherapy
Gifford SC, Strachan BC, Xia H, et al. (2018) A portable system for processing donated whole blood into high quality components without centrifugation. Plos One. 13: e0190827
Xia H, Khanal G, Strachan BC, et al. (2017) Washing in hypotonic saline reduces the fraction of irreversibly-damaged cells in stored blood: a proof-of-concept study. Blood Transfusion = Trasfusione Del Sangue. 1-9
Xia H, Strachan BC, Gifford SC, et al. (2016) A high-throughput microfluidic approach for 1000-fold leukocyte reduction of platelet-rich plasma. Scientific Reports. 6: 35943
Piety NZ, Gifford SC, Yang X, et al. (2015) Quantifying morphological heterogeneity: a study of more than 1 000 000 individual stored red blood cells. Vox Sanguinis
Gifford SC, Spillane AM, Vignes SM, et al. (2014) Controlled incremental filtration: a simplified approach to design and fabrication of high-throughput microfluidic devices for selective enrichment of particles. Lab On a Chip. 14: 4496-505
Yoshida T, AuBuchon JP, Dumont LJ, et al. (2008) The effects of additive solution pH and metabolic rejuvenation on anaerobic storage of red cells. Transfusion. 48: 2096-105
Gifford SC, Derganc J, Shevkoplyas SS, et al. (2006) A detailed study of time-dependent changes in human red blood cells: from reticulocyte maturation to erythrocyte senescence. British Journal of Haematology. 135: 395-404
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