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Michelle M. Le Beau

Affiliations: 
University of Chicago, Chicago, IL 
Area:
Cancer cytogenetics and genetics
Website:
http://t-aml.uchicago.edu/scientific-leadership/michelle-le-beau/
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"Michelle Le Beau"
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Children

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John M. Joslin grad student 2006 Chicago
Aparna Palakodeti grad student 2006 Chicago
Yanwen Jiang grad student 2007 Chicago
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Publications

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Stoddart A, Wang J, Fernald AA, et al. (2020) Cytotoxic Therapy-Induced Effects on Both Hematopoietic and Marrow Stromal Cells Promotes Therapy-Related Myeloid Neoplasms. Blood Cancer Discovery. 1
Meyer SE, Qin T, Muench DE, et al. (2016) Dnmt3a haploinsufficiency transforms Flt3-ITD myeloproliferative disease into a rapid, spontaneous, and fully-penetrant acute myeloid leukemia. Cancer Discovery
Stoddart A, Qian Z, Fernald AA, et al. (2016) Retroviral insertional mutagenesis identifies the del(5q) genes, CXXC5, TIFAB and ETF1, as well as the Wnt pathway, as potential targets in del(5q) myeloid neoplasms. Haematologica
Sundaravel S, Duggan R, Bhagat T, et al. (2015) Reduced DOCK4 expression leads to erythroid dysplasia in myelodysplastic syndromes. Proceedings of the National Academy of Sciences of the United States of America. 112: E6359-E6368
Amabile G, Di Ruscio A, Müller F, et al. (2015) Dissecting the role of aberrant DNA methylation in human leukaemia. Nature Communications. 6: 7091
Flach J, Bakker ST, Mohrin M, et al. (2014) Replication stress is a potent driver of functional decline in ageing haematopoietic stem cells. Nature. 512: 198-202
Young DJ, Stoddart A, Nakitandwe J, et al. (2014) Knockdown of Hnrnpa0, a del(5q) gene, alters myeloid cell fate in murine cells through regulation of AU-rich transcripts. Haematologica. 99: 1032-40
Stoddart A, Fernald AA, Wang J, et al. (2014) Haploinsufficiency of del(5q) genes, Egr1 and Apc, cooperate with Tp53 loss to induce acute myeloid leukemia in mice. Blood. 123: 1069-78
Dose M, Emmanuel AO, Chaumeil J, et al. (2014) β-Catenin induces T-cell transformation by promoting genomic instability. Proceedings of the National Academy of Sciences of the United States of America. 111: 391-6
Stoddart A, Wang J, Fernald AA, et al. (2014) Cell intrinsic and extrinsic factors synergize in mice with haploinsufficiency for Tp53, and two human del(5q) genes, Egr1 and Apc. Blood. 123: 228-38
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