Razvan D. Miclea, Ph.D.

Affiliations: 
2007 State University of New York, Buffalo, Buffalo, NY, United States 
Area:
General Biophysics, Pharmacy
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"Razvan Miclea"
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Sathy V. Balu-Iyer grad student 2007 SUNY Buffalo
 (Phosphatidylserine mediated enhancement of the therapeutic efficacy of B domain deleted recombinant factor VIII.)
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Kosloski MP, Peng A, Varma PR, et al. (2011) Immunogenicity and pharmacokinetic studies of recombinant factor VIII containing lipid cochleates. Drug Delivery. 18: 246-54
Peng A, Gaitonde P, Kosloski MP, et al. (2009) Effect of route of administration of human recombinant factor VIII on its immunogenicity in Hemophilia A mice. Journal of Pharmaceutical Sciences. 98: 4480-4
Kosloski MP, Miclea RD, Balu-Iyer SV. (2009) Role of glycosylation in conformational stability, activity, macromolecular interaction and immunogenicity of recombinant human factor VIII. The Aaps Journal. 11: 424-31
Ramani K, Purohit V, Miclea R, et al. (2008) Passive transfer of polyethylene glycol to liposomal-recombinant human FVIII enhances its efficacy in a murine model for hemophilia A. Journal of Pharmaceutical Sciences. 97: 3753-64
Ramani K, Miclea RD, Purohit VS, et al. (2008) Phosphatidylserine containing liposomes reduce immunogenicity of recombinant human factor VIII (rFVIII) in a murine model of hemophilia A. Journal of Pharmaceutical Sciences. 97: 1386-98
Miclea RD, Varma PR, Peng A, et al. (2007) Development and characterization of lipidic cochleate containing recombinant factor VIII. Biochimica Et Biophysica Acta. 1768: 2890-8
Miclea RD, Purohit VS, Balu-Iyer SV. (2007) O-phospho-L-serine, multi-functional excipient for B domain deleted recombinant factor VIII. The Aaps Journal. 9: E251-9
Ramani K, Purohit VS, Miclea RD, et al. (2005) Lipid binding region (2303-2332) is involved in aggregation of recombinant human FVIII (rFVIII) Journal of Pharmaceutical Sciences. 94: 1288-1299
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