Christopher C. Glembotski

Affiliations: 
Biology (Joint Doctoral SDSU) University of California, San Diego, La Jolla, CA 
Area:
Cell Biology, General Biophysics
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"Christopher Glembotski"
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Children

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Peter J. Belmont grad student 2010 UCSD
Shirin Doroudgar grad student 2012 UCSD
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Publications

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Hofmann C, Aghajani M, D Alcock C, et al. (2024) ATF6 protects against protein misfolding during cardiac hypertrophy. Journal of Molecular and Cellular Cardiology. 189: 12-24
Glembotski CC, Bagchi S, Blackwood EA. (2023) ER-Specific Autophagy or ER-Phagy in Cardiac Myocytes Protects the Heart Against Doxorubicin-Induced Cardiotoxicity. Jacc. Cardiooncology. 5: 671-673
Hofmann C, Löwenthal Z, Aghajani M, et al. (2023) mTORC1 inhibition impairs activation of the unfolded protein response and induces cell death during ER stress in cardiomyocytes. American Journal of Physiology. Heart and Circulatory Physiology
Blackwood EA, MacDonnell LF, Thuerauf DJ, et al. (2022) Noncanonical Form of ERAD Regulates Cardiac Hypertrophy. Circulation
Marsh KG, Arrieta A, Thuerauf DJ, et al. (2021) The peroxisomal enzyme, FAR1, is induced during ER stress in an ATF6-dependent manner in cardiac myocytes. American Journal of Physiology. Heart and Circulatory Physiology
Blackwood EA, Bilal AS, Azizi K, et al. (2020) Simultaneous Isolation and Culture of Atrial Myocytes, Ventricular Myocytes, and Non-Myocytes from an Adult Mouse Heart. Journal of Visualized Experiments : Jove
Blackwood EA, Thuerauf DJ, Stastna M, et al. (2020) Proteomic analysis of the cardiac myocyte secretome reveals extracellular protective functions for the ER stress response. Journal of Molecular and Cellular Cardiology
Arrieta A, Blackwood EA, Stauffer WT, et al. (2020) Mesencephalic astrocyte-derived neurotrophic factor is an ER-resident chaperone that protects against reductive stress in the heart. The Journal of Biological Chemistry
Glembotski CC, Arrieta A, Blackwood EA, et al. (2020) ATF6 as a Nodal Regulator of Proteostasis in the Heart. Frontiers in Physiology. 11: 267
Palmer JE, Brietske BM, Bate TC, et al. (2020) Reactive Oxygen Species (ROS)-Activatable Prodrug for Selective Activation of ATF6 after Ischemia/Reperfusion Injury. Acs Medicinal Chemistry Letters. 11: 292-297
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