Anil G. Cashikar

Affiliations: 
Medical College of Georgia, Augusta, GA, United States 
Area:
Molecular Biology, Biochemistry, General Biophysics
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Publications

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Toral-Rios D, Long JM, Ulrich JD, et al. (2024) Cholesterol 25-hydroxylase mediates neuroinflammation and neurodegeneration in a mouse model of tauopathy. The Journal of Experimental Medicine. 221
Litvinchuk A, Suh JH, Guo JL, et al. (2023) Amelioration of Tau and ApoE4-linked glial lipid accumulation and neurodegeneration with an LXR agonist. Neuron
Wong MY, Lewis M, Doherty JJ, et al. (2020) 25-Hydroxycholesterol amplifies microglial IL-1β production in an apoE isoform-dependent manner. Journal of Neuroinflammation. 17: 192
Czerniewski LR, Xiao Q, Bria K, et al. (2018) P1-194: Tracking The Intracellular Itinerary Of App And De Novo Amyloid Beta Generation Using Click Chemistry Alzheimers & Dementia. 14
Ojha J, Masilamoni G, Dunlap D, et al. (2011) Sequestration of toxic oligomers by HspB1 as a cytoprotective mechanism. Molecular and Cellular Biology. 31: 3146-57
Ojha J, Karmegam RV, Masilamoni JG, et al. (2011) Behavioral defects in chaperone-deficient Alzheimer's disease model mice. Plos One. 6: e16550
Mir SS, Fiedler D, Cashikar AG. (2009) Ssd1 is required for thermotolerance and Hsp104-mediated protein disaggregation in Saccharomyces cerevisiae. Molecular and Cellular Biology. 29: 187-200
Wendler P, Shorter J, Plisson C, et al. (2007) Atypical AAA+ Subunit Packing Creates an Expanded Cavity for Disaggregation by the Protein-Remodeling Factor Hsp104 Cell. 131: 1366-1377
Cooper AA, Gitler AD, Cashikar A, et al. (2006) Alpha-synuclein blocks ER-Golgi traffic and Rab1 rescues neuron loss in Parkinson's models. Science (New York, N.Y.). 313: 324-8
Cashikar AG, Duennwald M, Lindquist SL. (2005) A chaperone pathway in protein disaggregation. Hsp26 alters the nature of protein aggregates to facilitate reactivation by Hsp104. The Journal of Biological Chemistry. 280: 23869-75
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