Joachim Jaeger
Affiliations: | Biomedical Sciences | State University of New York, Albany, Albany, NY, United States |
Area:
Biochemistry, General BiophysicsGoogle:
"Joachim Jaeger"Mean distance: (not calculated yet)
Children
Sign in to add trainee| Chelsea L. Gridley | grad student | 2012 | SUNY Albany |
| Sneha Rangarajan | grad student | 2012 | SUNY Albany |
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Publications
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| Cherry AL, Dennis CA, Baron A, et al. (2015) Hydrophobic and charged residues in the C-terminal arm of hepatitis C virus RNA-dependent RNA polymerase regulate initiation and elongation. Journal of Virology. 89: 2052-63 |
| Gridley CL, Rangarajan S, Firbank S, et al. (2013) Structural changes in the hydrophobic hinge region adversely affect the activity and fidelity of the I260Q mutator DNA polymerase β. Biochemistry. 52: 4422-32 |
| Curti E, Jaeger J. (2013) Residues Arg283, Arg285, and Ile287 in the nucleotide binding pocket of bovine viral diarrhea virus NS5B RNA polymerase affect catalysis and fidelity. Journal of Virology. 87: 199-207 |
| Li Y, Gridley CL, Jaeger J, et al. (2012) Unfavorable electrostatic and steric interactions in DNA polymerase β E295K mutant interfere with the enzyme's pathway. Journal of the American Chemical Society. 134: 9999-10010 |
| Murphy DL, Donigan KA, Jaeger J, et al. (2012) The E288K colon tumor variant of DNA polymerase β is a sequence specific mutator. Biochemistry. 51: 5269-75 |
| Nemec AA, Donigan KA, Murphy DL, et al. (2012) Colon cancer-associated DNA polymerase β variant induces genomic instability and cellular transformation. The Journal of Biological Chemistry. 287: 23840-9 |
| Murphy DL, Jaeger J, Sweasy JB. (2011) A triad interaction in the fingers subdomain of DNA polymerase beta controls polymerase activity. Journal of the American Chemical Society. 133: 6279-87 |
| Yamtich J, Starcevic D, Lauper J, et al. (2010) Hinge residue I174 is critical for proper dNTP selection by DNA polymerase beta. Biochemistry. 49: 2326-34 |
| Lin GC, Jaeger J, Eckert KA, et al. (2009) Loop II of DNA polymerase beta is important for discrimination during substrate binding. Dna Repair. 8: 182-9 |
| Dalal S, Starcevic D, Jaeger J, et al. (2008) The I260Q variant of DNA polymerase beta extends mispaired primer termini due to its increased affinity for deoxynucleotide triphosphate substrates. Biochemistry. 47: 12118-25 |