Lianne McHardy, Ph.D.
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| Riffell JL, Zimmerman C, Khong A, et al. (2009) Effects of chemical manipulation of mitotic arrest and slippage on cancer cell survival and proliferation. Cell Cycle (Georgetown, Tex.). 8: 3025-38 |
| Kemmer D, McHardy LM, Hoon S, et al. (2009) Combining chemical genomics screens in yeast to reveal spectrum of effects of chemical inhibition of sphingolipid biosynthesis. Bmc Microbiology. 9: 9 |
| Sturgeon CM, Cinel B, Díaz-Marrero AR, et al. (2008) Abrogation of ionizing radiation-induced G2 checkpoint and inhibition of nuclear export by Cryptocarya pyrones. Cancer Chemotherapy and Pharmacology. 61: 407-13 |
| McHardy LM, Warabi K, Andersen RJ, et al. (2005) Strongylophorine-26, a Rho-dependent inhibitor of tumor cell invasion that reduces actin stress fibers and induces nonpolarized lamellipodial extensions. Molecular Cancer Therapeutics. 4: 772-8 |
| Warabi K, McHardy LM, Matainaho L, et al. (2004) Strongylophorine-26, a new meroditerpenoid isolated from the marine sponge Petrosia (Strongylophora) corticata that exhibits anti-invasion activity. Journal of Natural Products. 67: 1387-9 |
| Baetz K, McHardy L, Gable K, et al. (2004) Yeast genome-wide drug-induced haploinsufficiency screen to determine drug mode of action. Proceedings of the National Academy of Sciences of the United States of America. 101: 4525-30 |
| McHardy LM, Sinotte R, Troussard A, et al. (2004) The tumor invasion inhibitor dihydromotuporamine C activates RHO, remodels stress fibers and focal adhesions, and stimulates sodium-proton exchange. Cancer Research. 64: 1468-74 |
| Williams DE, Craig KS, Patrick B, et al. (2002) Motuporamines, anti-invasion and anti-angiogenic alkaloids from the marine sponge Xestospongia exigua (Kirkpatrick): isolation, structure elucidation, analogue synthesis, and conformational analysis. The Journal of Organic Chemistry. 67: 245-58 |
| Roskelley CD, Williams DE, McHardy LM, et al. (2001) Inhibition of tumor cell invasion and angiogenesis by motuporamines. Cancer Research. 61: 6788-94 |
| Britton R, De Silva ED, Bigg CM, et al. (2001) Synthetic transformations of eleutherobin reveal new features of its microtubule-stabilizing pharmacophore [20] Journal of the American Chemical Society. 123: 8632-8633 |