David Haselbach
Affiliations: | Max Planck Institute for Biophysical Chemistry, Göttingen, Göttingen, Niedersachsen, Germany |
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| Bodrug T, Welsh KA, Bolhuis DL, et al. (2023) Time-resolved cryo-EM (TR-EM) analysis of substrate polyubiquitination by the RING E3 anaphase-promoting complex/cyclosome (APC/C). Nature Structural & Molecular Biology |
| Hodáková Z, Grishkovskaya I, Brunner HL, et al. (2023) Cryo-EM structure of the chain-elongating E3 ubiquitin ligase UBR5. The Embo Journal. e113348 |
| Schimpf J, Oppermann S, Gerasimova T, et al. (2022) Structure of the peripheral arm of a minimalistic respiratory complex I. Structure (London, England : 1993). 30: 80-94.e4 |
| Grabarczyk DB, Petrova OA, Deszcz L, et al. (2021) HUWE1 employs a giant substrate-binding ring to feed and regulate its HECT E3 domain. Nature Chemical Biology |
| Watson ER, Grace CRR, Zhang W, et al. (2019) Protein engineering of a ubiquitin-variant inhibitor of APC/C identifies a cryptic K48 ubiquitin chain binding site. Proceedings of the National Academy of Sciences of the United States of America |
| Prajapati S, Haselbach D, Wittig S, et al. (2019) Structural and Functional Analyses of the Human PDH Complex Suggest a "Division-of-Labor" Mechanism by Local E1 and E3 Clusters. Structure (London, England : 1993) |
| Haselbach D, Komarov I, Agafonov DE, et al. (2018) Structure and Conformational Dynamics of the Human Spliceosomal Bact Complex. Cell |
| Bertram K, Agafonov DE, Dybkov O, et al. (2017) Cryo-EM Structure of a Pre-catalytic Human Spliceosome Primed for Activation. Cell |
| Haselbach D, Schrader J, Lambrecht F, et al. (2017) Long-range allosteric regulation of the human 26S proteasome by 20S proteasome-targeting cancer drugs. Nature Communications. 8: 15578 |
| Yamaguchi M, VanderLinden R, Weissmann F, et al. (2016) Cryo-EM of Mitotic Checkpoint Complex-Bound APC/C Reveals Reciprocal and Conformational Regulation of Ubiquitin Ligation. Molecular Cell |