Ira Tabas

Affiliations: 
Cellular Physiology and Biophysics Columbia University, New York, NY 
Area:
Medicine and Surgery, Physiology Biology
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"Ira Tabas"

Parents

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Stuart A. Kornfeld grad student 1981 Washington University (Chemistry Tree)
Alan Tall post-doc 1983-1985 Columbia

Children

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Andrew R. Leventhal grad student 2004 Columbia (Cell Biology Tree)
Arif Yurdagul, Jr. post-doc 2016- Columbia (Cell Biology Tree)
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Publications

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Sukka SR, Ampomah PB, Darville LNF, et al. (2024) Efferocytosis drives a tryptophan metabolism pathway in macrophages to promote tissue resolution. Nature Metabolism
Yalcinkaya M, Liu W, Thomas LA, et al. (2023) BRCC3-Mediated NLRP3 Deubiquitylation Promotes Inflammasome Activation and Atherosclerosis in Clonal Hematopoiesis. Circulation
Dai W, Zhang H, Lund H, et al. (2023) Intracellular tPA-PAI-1 interaction determines VLDL assembly in hepatocytes. Science (New York, N.Y.). 381: eadh5207
Liu W, Yalcinkaya M, Maestre IF, et al. (2023) Blockade of IL-6 signaling alleviates atherosclerosis in -deficient clonal hematopoiesis. Nature Cardiovascular Research. 2: 572-586
Schilperoort M, Ngai D, Sukka SR, et al. (2023) The role of efferocytosis-fueled macrophage metabolism in the resolution of inflammation. Immunological Reviews
Schilperoort M, Ngai D, Katerelos M, et al. (2023) PFKFB2-mediated glycolysis promotes lactate-driven continual efferocytosis by macrophages. Nature Metabolism
Ampomah PB, Cai B, Sukka SR, et al. (2022) Macrophages use apoptotic cell-derived methionine and DNMT3A during efferocytosis to promote tissue resolution. Nature Metabolism
Gerlach BD, Ampomah PB, Yurdagul A, et al. (2021) Efferocytosis induces macrophage proliferation to help resolve tissue injury. Cell Metabolism
Tao W, Yurdagul A, Kong N, et al. (2020) siRNA nanoparticles targeting CaMKIIγ in lesional macrophages improve atherosclerotic plaque stability in mice. Science Translational Medicine. 12
Liu L, Fan L, Chan M, et al. (2020) PPARγ Deacetylation Confers the Anti-Atherogenic Effect and Improves Endothelial Function in Diabetes Treatment. Diabetes
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