Brian K. Kobilka
Affiliations: | Molecular & Cellular Physiology | Stanford University, Palo Alto, CA |
Area:
Adrenergic receptorsWebsite:
http://med.stanford.edu/kobilkalab/index.htmlGoogle:
"Brian Kobilka"Bio:
The Nobel Prize in Chemistry 2012 was awarded jointly to Robert J. Lefkowitz and Brian K. Kobilka "for studies of G-protein-coupled receptors"
Cross-listing: Chemistry Tree - Neurotree
Parents
Sign in to add mentor| Robert M. Carlson | research assistant | University of Minnesota Duluth (Chemistry Tree) | ||
| Conrad E. Firling | research assistant | University of Minnesota Duluth | ||
| (A medium for the maintenance of Chironomus tentans salivary glands in vitro.) | ||||
| Robert J. Lefkowitz | post-doc | 1984-1989 | Duke (Neurotree) | |
Children
Sign in to add trainee| Andrew Kruse | grad student | Stanford (Chemistry Tree) | |
| Aashish Manglik | grad student | Stanford (Chemistry Tree) | |
| Yoon Seok Kim | grad student | 2015- | Stanford (Neurotree) |
| Pejman Ghanouni | grad student | 2001 | Stanford (Chemistry Tree) |
| Thomas P. Finsterbach | grad student | 2007 | Stanford (Chemistry Tree) |
| Carl M. Hurt | grad student | 2007 | Stanford (Chemistry Tree) |
| Juan J. Fung | grad student | 2009 | Stanford (Chemistry Tree) |
| Daniel Hilger | post-doc | Stanford (Chemistry Tree) | |
| Søren G.F. Rasmussen | post-doc | Stanford (Chemistry Tree) | |
| Daniel M. Rosenbaum | post-doc | Stanford (Chemistry Tree) | |
| Mark von Zastrow | post-doc | Stanford Medical School (Neurotree) | |
| John Janetzko | post-doc | 2017- | Stanford Medical School (Chemistry Tree) |
| Haoqing Wang | post-doc | 2019- | Stanford (Chemistry Tree) |
| Uwe Klein | post-doc | 1995-1998 | Stanford (Neurotree) |
| Peter Nollert | post-doc | 1999-2001 | Stanford (Chemistry Tree) |
| Ka Young Chung | post-doc | 2008-2011 | Stanford (Neurotree) |
| Hideaki E. Kato | post-doc | 2014-2019 | Stanford School of Medicine (Chemistry Tree) |
BETA: Related publications
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Publications
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| Heydenreich FM, Marti-Solano M, Sandhu M, et al. (2023) Molecular determinants of ligand efficacy and potency in GPCR signaling. Science (New York, N.Y.). 382: eadh1859 |
| Kumar KK, Wang H, Habrian C, et al. (2023) Step-wise activation of a Family C GPCR. Biorxiv : the Preprint Server For Biology |
| Toyoda Y, Zhu A, Kong F, et al. (2023) Structural basis of α-adrenergic receptor activation and recognition by an extracellular nanobody. Nature Communications. 14: 3655 |
| Zhao J, Elgeti M, O'Brien ES, et al. (2023) Conformational dynamics of the μ-opioid receptor determine ligand intrinsic efficacy. Biorxiv : the Preprint Server For Biology |
| Krishna Kumar K, Robertson MJ, Thadhani E, et al. (2023) Structural basis for activation of CB1 by an endocannabinoid analog. Nature Communications. 14: 2672 |
| Xu X, Shonberg J, Kaindl J, et al. (2023) Constrained catecholamines gain βAR selectivity through allosteric effects on pocket dynamics. Nature Communications. 14: 2138 |
| Heng J, Hu Y, Pérez-Hernández G, et al. (2023) Function and dynamics of the intrinsically disordered carboxyl terminus of β2 adrenergic receptor. Nature Communications. 14: 2005 |
| Krishna Kumar K, O'Brien ES, Habrian CH, et al. (2023) Negative allosteric modulation of the glucagon receptor by RAMP2. Cell. 186: 1465-1477.e18 |
| Papasergi-Scott MM, Pérez-Hernández G, Batebi H, et al. (2023) Time-resolved cryo-EM of G protein activation by a GPCR. Biorxiv : the Preprint Server For Biology |
| Xu J, Wang Q, Hübner H, et al. (2023) Structural and dynamic insights into supra-physiological activation and allosteric modulation of a muscarinic acetylcholine receptor. Nature Communications. 14: 376 |