Kevin Michael O'Shaughnessy, MB, BS, DPhil
Affiliations: | University of Oxford, Oxford, United Kingdom | ||
| Medicine | University of Cambridge, Cambridge, England, United Kingdom |
Area:
Hypertension, WNK pathway, Renal Physiology, Pre-eclampsia, medical genetics, arterial stiffness, Aldosterone, Conn's SyndromeWebsite:
http://emit.medschl.cam.ac.uk/people/investigators/dr-kevin-oshaughnessy/Google:
"Kevin O'Shaughnessy"Children
Sign in to add trainee| Sarah E. Cleary | research assistant | 2010- | Cambridge |
| Iris Hardege | grad student | 2013- | Cambridge |
| Raya Al Maskari | grad student | 2013- | Cambridge |
| Mark Glover | grad student | 2010 | Cambridge |
| Keith Siew | grad student | 2011-2019 | Cambridge |
| Meena Murthy | post-doc | Cambridge |
Collaborators
Sign in to add collaborator| Dario Renato Alessi | collaborator | ||
| Yasmin Yasmin | collaborator | 2005- | Cambridge |
| Ruth Murrell-Lagnado | collaborator | 2013- | Cambridge |
BETA: Related publications
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Publications
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| Siew K, Nestler KA, Nelson C, et al. (2024) Cosmic kidney disease: an integrated pan-omic, physiological and morphological study into spaceflight-induced renal dysfunction. Nature Communications. 15: 4923 |
| Louis-Dit-Picard H, Kouranti I, Rafael C, et al. (2020) Mutations affecting the conserved acidic WNK1 motif cause inherited hyperkalemic hyperchloremic acidosis. The Journal of Clinical Investigation |
| Murthy M, O'Shaughnessy KM. (2019) Modified HEK cells simulate DCT cells in their sensitivity and response to changes in extracellular K. Physiological Reports. 7: e14280 |
| Sandilands AJ, O'Shaughnessy KM, Yasmin Y. (2019) 1-adrenoceptor polymorphisms and blood pressure: 49S variant increases plasma renin but not blood pressure in hypertensive patients. American Journal of Hypertension |
| Maskari RA, Hardege I, Cleary S, et al. (2018) Functional characterization of common BCL11B gene desert variants suggests a lymphocyte-mediated association of BCL11B with aortic stiffness. European Journal of Human Genetics : Ejhg. 26: 1648-1657 |
| Yasmin, Maskari RA, McEniery CM, et al. (2018) The matrix proteins aggrecan and fibulin-1 play a key role in determining aortic stiffness. Scientific Reports. 8: 8550 |
| Hardege I, Long L, Al Maskari R, et al. (2017) Targeted disruption of the KCNJ5 gene in the female mouse lowers aldosterone levels. Clinical Science (London, England : 1979) |
| Ware JS, Wain LV, Channavajjhala SK, et al. (2017) Phenotypic and pharmacogenetic evaluation of patients with thiazide-induced hyponatremia. The Journal of Clinical Investigation. 127: 3367-3374 |
| Murthy M, Kurz T, O'Shaughnessy KM. (2016) WNK signalling pathways in blood pressure regulation. Cellular and Molecular Life Sciences : Cmls |
| Al Maskari R, Yasmin, Cleary S, et al. (2016) A missense TGFB2 variant p.(Arg320Cys) causes a paradoxical and striking increase in aortic TGFB1/2 expression. European Journal of Human Genetics : Ejhg |