Yong-jie Xu, Ph.D.
Affiliations: | 2007 | Johns Hopkins University, Baltimore, MD |
Area:
DNA replicationGoogle:
"Yong-jie Xu"Parents
Sign in to add mentor| Thomas J. Kelly | grad student | 2007 | Johns Hopkins | |
| (Molecular mechanism of the DNA replication checkpoint in the fission yeast Schizosaccharomyces pombe.) | ||||
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Publications
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| Ahamad N, Khan S, Xu YJ. (2020) The RecQ DNA helicase Rqh1 promotes Rad3 kinase signaling in the DNA replication checkpoint pathway of fission yeast. Molecular and Cellular Biology |
| Xu YJ, Khan S, Didier AC, et al. (2019) A mutation that destabilizes the Tel2-Tti1-Tti2 complex eliminates Rad3 kinase signaling in the DNA replication checkpoint and leads to telomere shortening in fission yeast. Molecular and Cellular Biology |
| Singh A, Xu YJ. (2017) Heme Deficiency Sensitizes Yeast Cells to Oxidative Stress Induced by Hydroxyurea. The Journal of Biological Chemistry |
| Singh A, Xu YJ. (2016) The Cell Killing Mechanisms of Hydroxyurea. Genes. 7 |
| Xu YJ, Singh A, Alter GM. (2016) Hydroxyurea Induces Cytokinesis Arrest in Cells Expressing a Mutated Sterol-14α-Demethylase in the Ergosterol Biosynthesis Pathway. Genetics |
| Xu YJ. (2015) Inner nuclear membrane protein Lem2 facilitates Rad3-mediated checkpoint signaling under replication stress induced by nucleotide depletion in fission yeast. Cellular Signalling |
| Yue M, Zeng L, Singh A, et al. (2014) Rad4 mainly functions in Chk1-mediated DNA damage checkpoint pathway as a scaffold protein in the fission yeast Schizosaccharomyces pombe. Plos One. 9: e92936 |
| Wang Z, Kim E, Leffak M, et al. (2012) Treslin, DUE-B, and GEMC1 cannot complement Sld3 mutants in fission yeast. Fems Yeast Research. 12: 486-90 |
| Yue M, Singh A, Wang Z, et al. (2011) The phosphorylation network for efficient activation of the DNA replication checkpoint in fission yeast. The Journal of Biological Chemistry. 286: 22864-74 |
| Xu YJ, Leffak M. (2010) ATRIP from TopBP1 to ATR--in vitro activation of a DNA damage checkpoint. Proceedings of the National Academy of Sciences of the United States of America. 107: 13561-2 |