Alan R. Lehmann

Affiliations: 
University of Sussex, Falmer, England, United Kingdom 
Area:
DNA repair
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"Alan Lehmann"

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Simone Sabbioneda grad student (Mycotree)
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Publications

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Giovannini S, Weibel L, Schittek B, et al. (2024) Skin cancer induction by the antimycotic drug voriconazole is caused by impaired DNA damage detection due to chromatin compaction. The Journal of Investigative Dermatology
Yurchenko AA, Rajabi F, Braz-Petta T, et al. (2023) Genomic mutation landscape of skin cancers from DNA repair-deficient xeroderma pigmentosum patients. Nature Communications. 14: 2561
Cipolla L, Bertoletti F, Maffia A, et al. (2019) UBR5 interacts with the replication fork and protects DNA replication from DNA polymerase η toxicity. Nucleic Acids Research
Theil AF, Botta E, Raams A, et al. (2019) Bi-allelic TARS Mutations Are Associated with Brittle Hair Phenotype. American Journal of Human Genetics. 105: 434-440
Abeti R, Zeitlberger A, Peelo C, et al. (2018) Xeroderma pigmentosum: overview of pharmacology and novel therapeutic strategies for neurological symptoms. British Journal of Pharmacology
Bertoletti F, Cea V, Liang CC, et al. (2017) Phosphorylation regulates human polη stability and damage bypass throughout the cell cycle. Nucleic Acids Research. 45: 9441-9454
Alt A, Dang HQ, Wells OS, et al. (2017) Specialized interfaces of Smc5/6 control hinge stability and DNA association. Nature Communications. 8: 14011
van der Crabben SN, Hennus MP, McGregor GA, et al. (2016) Destabilized SMC5/6 complex leads to chromosome breakage syndrome with severe lung disease. The Journal of Clinical Investigation
Kuschal C, Botta E, Orioli D, et al. (2016) GTF2E2 Mutations Destabilize the General Transcription Factor Complex TFIIE in Individuals with DNA Repair-Proficient Trichothiodystrophy. American Journal of Human Genetics
Fassihi H, Sethi M, Fawcett H, et al. (2016) Deep phenotyping of 89 xeroderma pigmentosum patients reveals unexpected heterogeneity dependent on the precise molecular defect. Proceedings of the National Academy of Sciences of the United States of America
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