Jay Tun-Chieh Yang

Affiliations: 
2012 Biochemistry University of Toronto, Toronto, ON, Canada 
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"Jay Yang"

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Grant W. Brown grad student 2012 University of Toronto
 (Characterization of the Roles of TopoIIIalpha-RMI1 in Maintaining Genome Integrity.)
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Publications

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Grote D, Moison C, Duhamel S, et al. (2015) E4F1 is a master regulator of CHK1-mediated functions. Cell Reports. 11: 210-9
Larin M, Gallo D, Tamblyn L, et al. (2014) Fanconi anemia signaling and Mus81 cooperate to safeguard development and crosslink repair. Nucleic Acids Research. 42: 9807-20
Xu D, Shen W, Guo R, et al. (2013) Top3β is an RNA topoisomerase that works with fragile X syndrome protein to promote synapse formation. Nature Neuroscience. 16: 1238-47
Grote D, Girard S, Chagraoui J, et al. (2013) The Bmi1-interacting protein E4f1 is vital for hematopoietic stem/progenitor cell function Experimental Hematology. 41: S15
Yang J, Bachrati CZ, Hickson ID, et al. (2012) BLM and RMI1 alleviate RPA inhibition of TopoIIIα decatenase activity. Plos One. 7: e41208
Yang J, O'Donnell L, Durocher D, et al. (2012) RMI1 promotes DNA replication fork progression and recovery from replication fork stress. Molecular and Cellular Biology. 32: 3054-64
Yang J, Bachrati CZ, Ou J, et al. (2010) Human topoisomerase IIIalpha is a single-stranded DNA decatenase that is stimulated by BLM and RMI1. The Journal of Biological Chemistry. 285: 21426-36
Xu D, Guo R, Sobeck A, et al. (2008) RMI, a new OB-fold complex essential for Bloom syndrome protein to maintain genome stability. Genes & Development. 22: 2843-55
Zhang C, Roberts TM, Yang J, et al. (2006) Suppression of genomic instability by SLX5 and SLX8 in Saccharomyces cerevisiae. Dna Repair. 5: 336-46
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