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Karl J. Fryxell

Affiliations: 
George Mason University, Washington, DC 
Area:
Molecular psychiatry, genetics
Website:
http://mason.gmu.edu/~kfryxell/
Google:
"Karl Fryxell"
Cross-listing: Neurotree

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Parents

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Jeremy P. Brockes grad student 1983 Caltech (Neurotree)

Children

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Theodor V. Jordan grad student 2005 George Mason (Neurotree)
Wonjong Moon grad student 2006 George Mason (Neurotree)
Mingkuan Lin grad student 2009 George Mason (Neurotree)
Laura L. Locklear grad student 2011 George Mason (Neurotree)
Nachiket Dharker grad student 2012 George Mason (Neurotree)
Robert T. Hallenberg grad student 2012 George Mason (Neurotree)
Ramya Sundararajan grad student 2012 George Mason (Neurotree)
Oksana O. Polesskaya post-doc 2005-2007 George Mason (Neurotree)

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Publications

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Murphy RL, Locklear LL, Niaz MH, et al. (2021) Nicotine preference and affective behavior of Cd81 knockout mice. Psychopharmacology
Leckie RL, Oberlin LE, Voss MW, et al. (2014) BDNF mediates improvements in executive function following a 1-year exercise intervention. Frontiers in Human Neuroscience. 8: 985
Greenwood PM, Lin MK, Sundararajan R, et al. (2014) Healthy aging increases the cognitive effects of two genes that influence extracellular dopamine. Psychology and Aging. 29: 363-73
Wheeler TL, Smith LN, Bachus SE, et al. (2013) Low-dose adolescent nicotine and methylphenidate have additive effects on adult behavior and neurochemistry. Pharmacology, Biochemistry, and Behavior. 103: 723-34
Locklear LL, McDonald CG, Smith RF, et al. (2012) Adult mice voluntarily progress to nicotine dependence in an oral self-selection assay. Neuropharmacology. 63: 582-92
Greenwood PM, Lin MK, Sundararajan R, et al. (2009) Synergistic effects of genetic variation in nicotinic and muscarinic receptors on visual attention but not working memory. Proceedings of the National Academy of Sciences of the United States of America. 106: 3633-8
Greenwood PM, Sundararajan R, Lin MK, et al. (2009) Both a nicotinic single nucleotide polymorphism (SNP) and a noradrenergic SNP modulate working memory performance when attention is manipulated. Journal of Cognitive Neuroscience. 21: 2139-53
Polesskaya OO, Fryxell KJ, Merchant AD, et al. (2007) Nicotine causes age-dependent changes in gene expression in the adolescent female rat brain. Neurotoxicology and Teratology. 29: 126-40
Polesskaya OO, Smith RF, Fryxell KJ. (2007) Chronic nicotine doses down-regulate PDE4 isoforms that are targets of antidepressants in adolescent female rats. Biological Psychiatry. 61: 56-64
Fryxell KJ, Moon WJ. (2005) CpG mutation rates in the human genome are highly dependent on local GC content. Molecular Biology and Evolution. 22: 650-8
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