| Year |
Citation |
Score |
| 2022 |
Siegfried JM. Sex and Gender Differences in Lung Cancer and Chronic Obstructive Lung Disease. Endocrinology. 163. PMID 34927202 DOI: 10.1210/endocr/bqab254 |
0.407 |
|
| 2021 |
Almotlak AA, Farooqui M, Soloff AC, Siegfried JM, Stabile LP. Targeting the ERβ/HER Oncogenic Network in Mutant Lung Cancer Modulates the Tumor Microenvironment and Is Synergistic with Sequential Immunotherapy. International Journal of Molecular Sciences. 23. PMID 35008514 DOI: 10.3390/ijms23010081 |
0.386 |
|
| 2020 |
Kilic O, Matos de Souza MR, Almotlak A, Wang Y, Siegfried J, Distefano MD, Wagner CR. Anti-EGFR Fibronectin Bispecific Chemically Self-Assembling Nanorings (CSANs) Induce Potent T-cell Mediated Anti-Tumor Response and Downregulation of EGFR Signaling and PD-1/PD-L1 Expression. Journal of Medicinal Chemistry. PMID 32852209 DOI: 10.1021/Acs.Jmedchem.0C00489 |
0.412 |
|
| 2020 |
Njatcha C, Farooqui M, Almotlak AA, Siegfried JM. Prevention of Tobacco Carcinogen-Induced Lung Tumor Development by a Novel STAT3 Decoy Inhibitor. Cancer Prevention Research (Philadelphia, Pa.). PMID 32655003 DOI: 10.1158/1940-6207.Capr-20-0033 |
0.498 |
|
| 2019 |
Almotlak AA, Farooqui M, Siegfried JM. Inhibiting pathways predicted from a steroid hormone gene signature yields synergistic anti-tumor effects in non-small cell lung cancer. Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. PMID 31606604 DOI: 10.1016/J.Jtho.2019.09.195 |
0.529 |
|
| 2019 |
Njatcha C, Wang J, Li H, Farooqui M, Siegfried JM. Abstract 3875: A novel STAT3 decoy inhibitor prevents lung cancer development Cancer Research. DOI: 10.1158/1538-7445.Sabcs18-3875 |
0.498 |
|
| 2019 |
Louiselle E, Miranda O, Li H, Boeder M, Li Z, Siegfried JM, Farooqui M. Abstract 2349: Modulation of inflammation in the tumor microenvironment by ER and PPARγ in an NNK-induced lung carcinogenesis model Immunology. DOI: 10.1158/1538-7445.Sabcs18-2349 |
0.431 |
|
| 2019 |
Almotlak AA, Farooqui M, Siegfried JM. Abstract 1027: Inhibiting pathways predicted from a steroid hormone gene signature yields synergistic antitumor effects in lung cancer Cancer Research. 79: 1027-1027. DOI: 10.1158/1538-7445.Am2019-1027 |
0.549 |
|
| 2018 |
Tsoyi K, Osorio JC, Chu SG, Fernandez IE, Poli S, Sholl L, Cui Y, Tellez CS, Siegfried JM, Belinsky SA, Perrella MA, El-Chemaly S, Rosas IO. Lung Adenocarcinoma Syndecan-2 Potentiates Cell Invasiveness. American Journal of Respiratory Cell and Molecular Biology. PMID 30562054 DOI: 10.1165/Rcmb.2018-0118Oc |
0.523 |
|
| 2018 |
Miranda O, Farooqui M, Siegfried JM. Status of Agents Targeting the HGF/c-Met Axis in Lung Cancer. Cancers. 10. PMID 30134579 DOI: 10.3390/Cancers10090280 |
0.521 |
|
| 2018 |
Garon EB, Siegfried JM, Stabile LP, Young PA, Marquez-Garban DC, Park DJ, Patel R, Hu EH, Sadeghi S, Parikh RJ, Reckamp KL, Adams B, Elashoff RM, Elashoff D, Grogan T, et al. Randomized phase II study of fulvestrant and erlotinib compared with erlotinib alone in patients with advanced or metastatic non-small cell lung cancer. Lung Cancer (Amsterdam, Netherlands). 123: 91-98. PMID 30089602 DOI: 10.1016/J.Lungcan.2018.06.013 |
0.513 |
|
| 2018 |
Njatcha C, Farooqui M, Kornberg A, Johnson DE, Grandis JR, Siegfried JM. STAT3 Cyclic Decoy Demonstrates Robust Antitumor Effects in Non-Small Cell Lung Cancer. Molecular Cancer Therapeutics. PMID 29891486 DOI: 10.1158/1535-7163.Mct-17-1194 |
0.486 |
|
| 2018 |
Leng S, Diergaarde B, Picchi MA, Wilson DO, Gilliland FD, Yuan JM, Siegfried JM, Belinsky SA. Gene Promoter Hypermethylation Detected in Sputum Predicts FEV1 Decline and All-cause Mortality in Smokers. American Journal of Respiratory and Critical Care Medicine. PMID 29437466 DOI: 10.1164/Rccm.201708-1659Oc |
0.405 |
|
| 2017 |
Stabile LP, Farooqui M, Kanterewicz B, Abberbock S, Kurland BF, Diergaarde B, Siegfried JM. Preclinical Evidence for Combined Use of Aromatase Inhibitors and NSAIDs as Preventive Agents of Tobacco-Induced Lung Cancer. Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. PMID 29233790 DOI: 10.1016/J.Jtho.2017.11.126 |
0.559 |
|
| 2017 |
Leng S, Wu G, Klinge DM, Thomas CL, Casas E, Picchi MA, Stidley CA, Lee SJ, Aisner S, Siegfried JM, Ramalingam S, Khuri FR, Karp DD, Belinsky SA. Gene methylation biomarkers in sputum as a classifier for lung cancer risk. Oncotarget. 8: 63978-63985. PMID 28969046 DOI: 10.18632/Oncotarget.19255 |
0.458 |
|
| 2017 |
Korde A, Jin L, Zhang JG, Ramaswamy A, Hu B, Kolahian S, Juan Guardela B, Herazo-Maya J, Siegfried JM, Stabile L, Pisani MA, Herbst RS, Kaminski N, Elias JA, Puchalski JT, et al. Lung Endothelial MicroRNA-1 Regulates Tumor Growth and Angiogenesis. American Journal of Respiratory and Critical Care Medicine. PMID 28853613 DOI: 10.1164/Rccm.201610-2157Oc |
0.395 |
|
| 2017 |
Leng S, Wu G, Klinge DM, Thomas CL, Casas E, Picchi MA, Stidley CA, Lee SJ, Aisner S, Siegfried JM, Ramalingam S, Khuri FR, Karp DD, Belinsky SA. Gene methylation biomarkers in sputum as a classifier for lung cancer risk. Oncotarget. PMID 28754865 DOI: 10.18632/oncotarget.19255 |
0.355 |
|
| 2017 |
Barón AE, Kako S, Feser WJ, Malinowski H, Merrick D, Garg K, Malkoski S, Pretzel S, Siegfried JM, Franklin WA, Miller Y, Wolf HJ, Varella-Garcia M. Clinical Utility of Chromosomal Aneusomy in Individuals at High Risk of Lung Cancer. Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. PMID 28634123 DOI: 10.1016/J.Jtho.2017.06.008 |
0.408 |
|
| 2017 |
Tarhini AA, Rafique I, Floros T, Tran P, Gooding WE, Villaruz LC, Burns TF, Friedland DM, Petro DP, Farooqui M, Gomez-Garcia J, Gaither-Davis A, Dacic S, Argiris A, Socinski MA, ... ... Siegfried JM, et al. Phase 1/2 study of rilotumumab (AMG 102), a hepatocyte growth factor inhibitor, and erlotinib in patients with advanced non-small cell lung cancer. Cancer. PMID 28472537 DOI: 10.1002/Cncr.30717 |
0.504 |
|
| 2017 |
Siegfried JM, Farooqui M, Rothenberger NJ, Dacic S, Stabile LP. Interaction between the estrogen receptor and fibroblast growth factor receptor pathways in non-small cell lung cancer. Oncotarget. 8: 24063-24076. PMID 28445992 DOI: 10.18632/Oncotarget.16030 |
0.49 |
|
| 2017 |
Zhou J, Qu Z, Sun F, Han L, Li L, Yan S, Stabile LP, Chen LF, Siegfried JM, Xiao G. Myeloid STAT3 promotes lung tumorigenesis by transforming tumor immunosurveillance into tumor-promoting inflammation. Cancer Immunology Research. PMID 28108629 DOI: 10.1158/2326-6066.Cir-16-0073 |
0.437 |
|
| 2017 |
Njatcha C, Farooqui M, Grandis JR, Siegfried JM. Abstract 4101: Targeting the EGFR/STAT3 axis in NSCLC with resistance to EGFR tyrosine kinase inhibitors using an oligonucleotide-based decoy Cancer Research. 77: 4101-4101. DOI: 10.1158/1538-7445.Am2017-4101 |
0.463 |
|
| 2017 |
Picchi MA, Leng S, Wu G, Klinge DM, Thomas CL, Casas E, Stidley CA, Lee SJ, Aisner S, Siegfried JM, Ramalingam S, Khuri FR, Karp DD, Belinsky SA. Abstract 3261: Gene methylation biomarkers in sputum as a classifier for lung cancer risk Cancer Research. 77: 3261-3261. DOI: 10.1158/1538-7445.Am2017-3261 |
0.451 |
|
| 2017 |
Stabile LP, Rothenberger NJ, Farooqui M, Dacic S, Siegfried JM. Abstract 1005: Interaction between the estrogen receptor and fibroblast growth factor receptor pathways in non-small cell lung cancer Endocrinology. 77: 1005-1005. DOI: 10.1158/1538-7445.Am2017-1005 |
0.49 |
|
| 2016 |
Villaruz LC, Jones H, Dacic S, Abberbock S, Kurland BF, Stabile LP, Siegfried JM, Conrads TP, Smith NR, O'Connor MJ, Pierce AJ, Bakkenist CJ. ATM protein is deficient in over 40% of lung adenocarcinomas. Oncotarget. PMID 27259260 DOI: 10.18632/Oncotarget.9757 |
0.535 |
|
| 2016 |
Gao W, Jin J, Yin J, Land S, Gaither-Davis A, Christie N, Luketich JD, Siegfried JM, Keohavong P. KRAS and TP53 mutations in bronchoscopy samples from former lung cancer patients. Molecular Carcinogenesis. PMID 27182622 DOI: 10.1002/Mc.22501 |
0.48 |
|
| 2016 |
Stabile LP, Tarhini AA, Farooqui M, Gomez-Garcia J, Gaither-Davis A, Gooding WE, Socinski MA, Siegfried JM. Association of high circulating neuregulin-1 with clinical benefit in EGFR wild-type NSCLC patients treated with rilotumumab and erlotinib. Journal of Clinical Oncology. 34. DOI: 10.1200/Jco.2016.34.15_Suppl.E20647 |
0.341 |
|
| 2015 |
Siegfried JM, Lin Y, Diergaarde B, Lin HM, Dacic S, Pennathur A, Weissfeld JL, Romkes M, Nukui T, Stabile LP. Expression of PAM50 Genes in Lung Cancer: Evidence that Interactions between Hormone Receptors and HER2/HER3 Contribute to Poor Outcome. Neoplasia (New York, N.Y.). 17: 817-25. PMID 26678909 DOI: 10.1016/J.Neo.2015.11.002 |
0.519 |
|
| 2015 |
Beumer JH, Fu KY, Anyang BN, Siegfried JM, Bakkenist CJ. Functional analyses of ATM, ATR and Fanconi anemia proteins in lung carcinoma : ATM, ATR and FA in lung carcinoma. Bmc Cancer. 15: 649. PMID 26438152 DOI: 10.1186/S12885-015-1649-3 |
0.437 |
|
| 2015 |
Weissfeld JL, Lin Y, Lin HM, Kurland BF, Wilson DO, Fuhrman CR, Pennathur A, Romkes M, Nukui T, Yuan JM, Siegfried JM, Diergaarde B. Lung cancer risk prediction using common SNPs located in GWAS-identified susceptibility regions. Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. PMID 26352532 DOI: 10.1097/Jto.0000000000000666 |
0.44 |
|
| 2015 |
Sun F, Qu Z, Xiao Y, Zhou J, Burns TF, Stabile LP, Siegfried JM, Xiao G. NF-κB1 p105 suppresses lung tumorigenesis through the Tpl2 kinase but independently of its NF-κB function. Oncogene. PMID 26300007 DOI: 10.1038/Onc.2015.299 |
0.4 |
|
| 2015 |
Tessema M, Yingling CM, Picchi MA, Wu G, Liu Y, Weissfeld JL, Siegfried JM, Tesfaigzi Y, Belinsky SA. Epigenetic Repression of CCDC37 and MAP1B Links Chronic Obstructive Pulmonary Disease to Lung Cancer. Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. 10: 1181-8. PMID 26200272 DOI: 10.1097/Jto.0000000000000592 |
0.444 |
|
| 2015 |
Leng S, Liu Y, Weissfeld JL, Thomas CL, Han Y, Picchi MA, Edlund CK, Willink RP, Gaither Davis AL, Do KC, Nukui T, Zhang X, Burki EA, Van Den Berg D, Romkes M, ... ... Siegfried JM, et al. 15q12 variants, sputum gene promoter hypermethylation, and lung cancer risk: a GWAS in smokers. Journal of the National Cancer Institute. 107. PMID 25713168 DOI: 10.1093/Jnci/Djv035 |
0.527 |
|
| 2015 |
Dixit R, Weissfeld JL, Wilson DO, Balogh P, Sufka P, Siegfried JM, Grandis JR, Diergaarde B. Incidence of head and neck squamous cell carcinoma among subjects at high risk of lung cancer: results from the Pittsburgh Lung Screening Study. Cancer. 121: 1431-5. PMID 25559556 DOI: 10.1002/Cncr.29189 |
0.427 |
|
| 2015 |
Siegfried JM, Shang K, Reilly C, Stabile LP. Abstract 2181: Differential expression of genes related to autoimmunity and metabolism in Stage I NSCLC from patients with COPD Cancer Research. 75: 2181-2181. DOI: 10.1158/1538-7445.Am2015-2181 |
0.305 |
|
| 2015 |
Stabile LP, Rothenberger NJ, Romkes M, Koodie L, Farooqui M, Dacic S, Siegfried JM. Abstract 1861: Estrogen modulation of fibroblast growth factor signaling in non-small cell lung cancer Cancer Research. 75: 1861-1861. DOI: 10.1158/1538-7445.Am2015-1861 |
0.531 |
|
| 2014 |
Yu G, Herazo-Maya JD, Nukui T, Romkes M, Parwani A, Juan-Guardela BM, Robertson J, Gauldie J, Siegfried JM, Kaminski N, Kass DJ. Matrix metalloproteinase-19 promotes metastatic behavior in vitro and is associated with increased mortality in non-small cell lung cancer. American Journal of Respiratory and Critical Care Medicine. 190: 780-90. PMID 25250855 DOI: 10.1164/Rccm.201310-1903Oc |
0.476 |
|
| 2014 |
Weissfeld JL, Diergaarde B, Nukui T, Buch S, Pennathur A, Socinski MA, Siegfried JM, Romkes M. Inherited variation in the ATP-binding cassette transporter ABCB1 and survival after chemotherapy for stage III-IV lung cancer. Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. 9: 1264-71. PMID 25122423 DOI: 10.1097/Jto.0000000000000262 |
0.389 |
|
| 2014 |
Mehan MR, Williams SA, Siegfried JM, Bigbee WL, Weissfeld JL, Wilson DO, Pass HI, Rom WN, Muley T, Meister M, Franklin W, Miller YE, Brody EN, Ostroff RM. Validation of a blood protein signature for non-small cell lung cancer. Clinical Proteomics. 11: 32. PMID 25114662 DOI: 10.1186/1559-0275-11-32 |
0.448 |
|
| 2014 |
Stabile LP, Rothstein ME, Gubish CT, Cunningham DE, Lee N, Siegfried JM. Co-targeting c-Met and COX-2 leads to enhanced inhibition of lung tumorigenesis in a murine model with heightened airway HGF. Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. 9: 1285-93. PMID 25057941 DOI: 10.1097/Jto.0000000000000245 |
0.523 |
|
| 2014 |
Gross ND, Bauman JE, Gooding WE, Denq W, Thomas SM, Wang L, Chiosea S, Hood BL, Flint MS, Sun M, Conrads TP, Ferris RL, Johnson JT, Kim S, Argiris A, ... ... Siegfried JM, et al. Erlotinib, erlotinib-sulindac versus placebo: a randomized, double-blind, placebo-controlled window trial in operable head and neck cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 20: 3289-98. PMID 24727329 DOI: 10.1158/1078-0432.Ccr-13-3360 |
0.354 |
|
| 2014 |
Ng YK, Lee JY, Supko KM, Khan A, Torres SM, Berwick M, Ho J, Kirkwood JM, Siegfried JM, Stabile LP. Pan-erbB inhibition potentiates BRAF inhibitors for melanoma treatment. Melanoma Research. 24: 207-18. PMID 24709886 DOI: 10.1097/Cmr.0000000000000060 |
0.376 |
|
| 2014 |
Siegfried JM, Stabile LP. Estrongenic steroid hormones in lung cancer. Seminars in Oncology. 41: 5-16. PMID 24565577 DOI: 10.1053/J.Seminoncol.2013.12.009 |
0.508 |
|
| 2014 |
Bruse S, Petersen H, Weissfeld J, Picchi M, Willink R, Do K, Siegfried J, Belinsky SA, Tesfaigzi Y. Increased methylation of lung cancer-associated genes in sputum DNA of former smokers with chronic mucous hypersecretion. Respiratory Research. 15: 2. PMID 24405663 DOI: 10.1186/1465-9921-15-2 |
0.455 |
|
| 2014 |
Siegfried JM. Smoking out reproductive hormone actions in lung cancer. Molecular Cancer Research : McR. 12: 24-31. PMID 24398390 DOI: 10.1158/1541-7786.Mcr-13-0580 |
0.486 |
|
| 2014 |
Dacic S, Luvison A, Evdokimova V, Kelly L, Siegfried JM, Villaruz LC, Socinski MA, Nikiforov YE. RET rearrangements in lung adenocarcinoma and radiation. Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. 9: 118-20. PMID 24346100 DOI: 10.1097/Jto.0000000000000015 |
0.428 |
|
| 2014 |
Brahmer JR, Lee JW, Traynor AM, Hidalgo MM, Kolesar JM, Siegfried JM, Guaglianone PP, Patel JD, Keppen MD, Schiller JH. Dosing to rash: a phase II trial of the first-line erlotinib for patients with advanced non-small-cell lung cancer an Eastern Cooperative Oncology Group Study (E3503). European Journal of Cancer (Oxford, England : 1990). 50: 302-8. PMID 24246704 DOI: 10.1016/J.Ejca.2013.10.006 |
0.362 |
|
| 2014 |
Gau C, LaDuca H, Lu H, Stuenkel A, Pesaran T, Chen E, Siegfried J, Mexal S, Hoiness R, Cook J, Copenhaver J, Chao E. Abstract 14: Identification of probands with multiple mutations in cancer susceptibility genes using a multigene panel approach Cancer Research. 74: 14-14. DOI: 10.1158/1538-7445.Cansusc14-14 |
0.349 |
|
| 2014 |
Stabile LP, Rothstein ME, Kurland BF, Cunningham D, Orlowski M, Siegfried JM. Abstract 608: Targeting the estrogen pathway in a male mouse model of lung tumor prevention Cancer Research. 74: 608-608. DOI: 10.1158/1538-7445.Am2014-608 |
0.517 |
|
| 2014 |
Ostroff R, Mehan MR, Williams S, Brody E, Pass H, Rom W, Siegfried J, Muley T, Franklin W, Merrick D, Bokhoven Av, Wolf H, Feser W, Barón AE, Miller Y. Abstract PR04: Distinctive squamous cell carcinoma protein signatures. Clinical Cancer Research. 20: PR04-PR04. DOI: 10.1158/1078-0432.14Aacriaslc-Pr04 |
0.479 |
|
| 2014 |
Siegfried JM, Lin Y, Dacic S, Diergaarde B, Stabile LP, Lin H, Romkes M. Abstract B20: Prediction of lung cancer survival by genes in the PAM50 breast cancer panel. Clinical Cancer Research. 20. DOI: 10.1158/1078-0432.14Aacriaslc-B20 |
0.525 |
|
| 2014 |
Siegfried J, Lin Y, Dacic S, Stabile L, Diergaarde B, Lin H, Nukui T, Romkes M. Prediction of NSCLC Survival With the PAM50 Breast Cancer Signature International Journal of Radiation Oncology*Biology*Physics. 90: S71-S72. DOI: 10.1016/J.Ijrobp.2014.08.306 |
0.342 |
|
| 2014 |
Villaruz L, Socinski M, Derrick V, Bartoluzzi S, Kurland B, Nikiforova M, Burns T, Siegfried J, Hamilton R, Dacic S. Enrichment of Met Amplification and Kras Mutations in Non-Small Cell Lung Carcinoma (NSCLC) Brain Metastases International Journal of Radiation Oncology*Biology*Physics. 90: S35-S36. DOI: 10.1016/J.Ijrobp.2014.08.212 |
0.457 |
|
| 2013 |
Tarhini AA, Zahoor H, McLaughlin B, Gooding WE, Schmitz JC, Siegfried JM, Socinski MA, Argiris A. Phase I trial of carboplatin and etoposide in combination with panobinostat in patients with lung cancer. Anticancer Research. 33: 4475-81. PMID 24123018 |
0.351 |
|
| 2013 |
Song JY, Siegfried JM, Diergaarde B, Land SR, Bowser R, Stabile LP, Dacic S, Dhir R, Nukui T, Romkes M, Weissfeld JL. Genetic variation in ESR2 and estrogen receptor-beta expression in lung tumors. Cancer Epidemiology. 37: 518-22. PMID 23619141 DOI: 10.1016/J.Canep.2013.03.020 |
0.423 |
|
| 2013 |
Villaruz LC, Socinski MA, Cunningham DE, Chiosea SI, Burns TF, Siegfried JM, Dacic S. The prognostic and predictive value of KRAS oncogene substitutions in lung adenocarcinoma Cancer. 119: 2268-2274. PMID 23526491 DOI: 10.1002/Cncr.28039 |
0.466 |
|
| 2013 |
Stabile LP, He G, Lui VW, Thomas S, Henry C, Gubish CT, Joyce S, Quesnelle KM, Siegfried JM, Grandis JR. c-Src activation mediates erlotinib resistance in head and neck cancer by stimulating c-Met. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 19: 380-92. PMID 23213056 DOI: 10.1158/1078-0432.Ccr-12-1555 |
0.382 |
|
| 2013 |
Egloff AM, Liu X, Davis AL, Trevelline BK, Vuga M, Siegfried JM, Grandis JR. Elevated gastrin-releasing peptide receptor mRNA expression in buccal mucosa: association with head and neck squamous cell carcinoma. Head & Neck. 35: 270-9. PMID 22431275 DOI: 10.1002/Hed.22963 |
0.316 |
|
| 2013 |
Patel A, Doyle T, Liu Y, Hatabu H, Nishino Hatabu M, Okajima Y, Risquez C, Shi Y, Osorio J, Golzarri M, Lederer J, El-Chemaly S, Pinto-Plata V, Celli B, Hunninghake G, ... ... Siegfried J, et al. A Peripheral Blood Biomarker Signature Potentially Identifies Smokers with Interstitial Lung Abnormalities Chest. 144: 1029A. DOI: 10.1378/Chest.1778676 |
0.405 |
|
| 2013 |
Odell D, Wizorek J, Schuchert M, McCormick K, Wilson D, Siegfried J, Luketich J, Landreneau R. The Impact of Microscopically Positive Final Pathologic Margins Identified Days After Surgery in Resected Non-small Cell Lung Cancer (NSCLC) Chest. 144: 116. DOI: 10.1378/Chest.1702017 |
0.478 |
|
| 2013 |
Schuchert MJ, Wizorek JJ, Normolle DP, Wilson DO, Siegfried J, Awais O, Abbas G, Luketich JD, Landreneau RJ. Has the paradigm changed away from lobectomy for stage I non-small cell lung cancer (NSCLC)? Anatomic segmentectomy: Surgery’s answer to image-guided ablation/radiation therapy for the small peripheral lung lesion. Journal of Clinical Oncology. 31: 7577-7577. DOI: 10.1200/Jco.2013.31.15_Suppl.7577 |
0.428 |
|
| 2013 |
Bauman JE, Gross ND, Gooding WE, Denq W, Thomas SM, Wang L, Chiosea SI, Hood BL, Flint MS, Sun M, Conrads TP, Ferris RL, Johnson JT, Kim S, Argiris A, ... ... Siegfried J, et al. Neoadjuvant erlotinib, erlotinib-sulindac, or placebo: A randomized, double-blind biomarker modulation study in operable head and neck squamous cell carcinoma (HNSCC). Journal of Clinical Oncology. 31: 6051-6051. DOI: 10.1200/Jco.2013.31.15_Suppl.6051 |
0.404 |
|
| 2013 |
Garon EB, Siegfried JM, Dubinett SM, Elashoff RM, Park DJ, Parikh RJ, Patel R, Hu EH, Reckamp KL, Adams B, Martinez D, Wang H, Kabbinavar F, Dacic S, Brennan M, et al. Abstract 4664: Result of TORI L-03, a randomized, multicenter phase II clinical trial of erlotinib (E) or E + fulvestrant (F) in previously treated advanced non-small cell lung cancer (NSCLC). Cancer Research. 73: 4664-4664. DOI: 10.1158/1538-7445.Am2013-4664 |
0.439 |
|
| 2013 |
Stabile LP, Rothstein ME, Gubish CT, Lee N, Cunningham DE, Siegfried JM. Abstract 2026: Co-targeting c-Met and COX-2 leads to enhanced inhibition of lung tumorigenesis in a murine model with heightened HGF signaling in the airways. Cancer Research. 73: 2026-2026. DOI: 10.1158/1538-7445.Am2013-2026 |
0.53 |
|
| 2013 |
Stabile LP, He G, Lui VW, Thomas S, Henry C, Gubish CT, Joyce S, Quesnelle KM, Siegfried JM, Grandis. Correction: c-Src activation mediates erlotinib resistance in head and neck cancer by stimulating c-Met (Clinical Cancer Research (2013) 19, (380-392)) Clinical Cancer Research. 19. DOI: 10.1158/1078-0432.Ccr-13-1344 |
0.352 |
|
| 2012 |
Henry C, Lopez-Chavez A, Stabile LP, Siegfried JM. HGF Airway Over-expression Leads to Enhanced Pulmonary Vascularization without Induction of VEGF. Current Angiogenesis. 1: 52-63. PMID 33564620 DOI: 10.2174/2211552811201010052 |
0.329 |
|
| 2012 |
Meng X, Qiang Y, Zhu S, Fuhrman C, Siegfried JM, Pu J. Illustration of the obstacles in computerized lung segmentation using examples. Medical Physics. 39: 4984-91. PMID 22894423 DOI: 10.1118/1.4737023 |
0.424 |
|
| 2012 |
Stabile LP, Rothstein ME, Cunningham DE, Land SR, Dacic S, Keohavong P, Siegfried JM. Prevention of tobacco carcinogen-induced lung cancer in female mice using antiestrogens Carcinogenesis. 33: 2181-2189. PMID 22859269 DOI: 10.1093/Carcin/Bgs260 |
0.539 |
|
| 2012 |
Flores KG, Stidley CA, Mackey AJ, Picchi MA, Stabler SP, Siegfried JM, Byers T, Berwick M, Belinsky SA, Leng S. Sex-specific association of sequence variants in CBS and MTRR with risk for promoter hypermethylation in the lung epithelium of smokers. Carcinogenesis. 33: 1542-7. PMID 22665368 DOI: 10.1093/Carcin/Bgs194 |
0.333 |
|
| 2012 |
Pu J, Gu S, Liu S, Zhu S, Wilson D, Siegfried JM, Gur D. CT based computerized identification and analysis of human airways: a review. Medical Physics. 39: 2603-16. PMID 22559631 DOI: 10.1118/1.4703901 |
0.343 |
|
| 2012 |
Schuchert MJ, Abbas G, Awais O, Pennathur A, Nason KS, Wilson DO, Siegfried JM, Luketich JD, Landreneau RJ. Anatomic segmentectomy for the solitary pulmonary nodule and early-stage lung cancer. The Annals of Thoracic Surgery. 93: 1780-5; discussion 1. PMID 22483652 DOI: 10.1016/J.Athoracsur.2011.11.074 |
0.471 |
|
| 2012 |
Bigbee WL, Gopalakrishnan V, Weissfeld JL, Wilson DO, Dacic S, Lokshin AE, Siegfried JM. A multiplexed serum biomarker immunoassay panel discriminates clinical lung cancer patients from high-risk individuals found to be cancer-free by CT screening. Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. 7: 698-708. PMID 22425918 DOI: 10.1097/Jto.0B013E31824Ab6B0 |
0.411 |
|
| 2012 |
Schuchert MJ, Awais O, Abbas G, Horne ZD, Nason KS, Pennathur A, Souza AP, Siegfried JM, Wilson DO, Luketich JD, Landreneau RJ. Influence of age and IB status after resection of node-negative non-small cell lung cancer. The Annals of Thoracic Surgery. 93: 929-35; discussion 9. PMID 22364984 DOI: 10.1016/J.Athoracsur.2011.09.047 |
0.494 |
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| 2012 |
Wheeler S, Siwak DR, Chai R, LaValle C, Seethala RR, Wang L, Cieply K, Sherer C, Joy C, Mills GB, Argiris A, Siegfried JM, Grandis JR, Egloff AM. Tumor epidermal growth factor receptor and EGFR PY1068 are independent prognostic indicators for head and neck squamous cell carcinoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 18: 2278-89. PMID 22351687 DOI: 10.1158/1078-0432.Ccr-11-1593 |
0.373 |
|
| 2012 |
Egloff AM, Gaither Davis A, Shuai Y, Land S, Pilewski JM, Luketich JD, Landreneau R, Miller YE, Grandis JR, Siegfried JM. Gastrin-releasing peptide receptor expression in non-cancerous bronchial epithelia is associated with lung cancer: a case-control study. Respiratory Research. 13: 9. PMID 22296774 DOI: 10.1186/1465-9921-13-9 |
0.482 |
|
| 2012 |
Siegfried JM, Gubish CT, Rothstein ME, Henry C, Stabile LP. Combining the multitargeted tyrosine kinase inhibitor vandetanib with the antiestrogen fulvestrant enhances its antitumor effect in non-small cell lung cancer. Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. 7: 485-95. PMID 22258476 DOI: 10.1097/Jto.0B013E31824177Ea |
0.519 |
|
| 2012 |
Carr SR, Schuchert MJ, Pennathur A, Wilson DO, Siegfried JM, Luketich JD, Landreneau RJ. Impact of tumor size on outcomes after anatomic lung resection for stage 1A non-small cell lung cancer based on the current staging system. The Journal of Thoracic and Cardiovascular Surgery. 143: 390-7. PMID 22169444 DOI: 10.1016/J.Jtcvs.2011.10.023 |
0.495 |
|
| 2012 |
Tessema M, Yingling CM, Thomas CL, Klinge DM, Bernauer AM, Liu Y, Dacic S, Siegfried JM, Dahlberg SE, Schiller JH, Belinsky SA. SULF2 methylation is prognostic for lung cancer survival and increases sensitivity to topoisomerase-I inhibitors via induction of ISG15. Oncogene. 31: 4107-16. PMID 22158045 DOI: 10.1038/Onc.2011.577 |
0.521 |
|
| 2012 |
Leng S, Stidley CA, Liu Y, Edlund CK, Willink RP, Han Y, Landi MT, Thun M, Picchi MA, Bruse SE, Crowell RE, Van Den Berg D, Caporaso NE, Amos CI, Siegfried JM, et al. Genetic determinants for promoter hypermethylation in the lungs of smokers: a candidate gene-based study. Cancer Research. 72: 707-15. PMID 22139380 DOI: 10.1158/0008-5472.Can-11-3194 |
0.422 |
|
| 2012 |
Wilson DO, Ryan A, Fuhrman C, Schuchert M, Shapiro S, Siegfried JM, Weissfeld J. Doubling times and CT screen-detected lung cancers in the Pittsburgh lung screening study American Journal of Respiratory and Critical Care Medicine. 185: 85-89. PMID 21997335 DOI: 10.1164/Rccm.201107-1223Oc |
0.492 |
|
| 2012 |
Buch SC, Diergaarde B, Nukui T, Day RS, Siegfried JM, Romkes M, Weissfeld JL. Genetic variability in DNA repair and cell cycle control pathway genes and risk of smoking-related lung cancer. Molecular Carcinogenesis. 51: E11-20. PMID 21976407 DOI: 10.1002/Mc.20858 |
0.4 |
|
| 2012 |
Schuchert M, Macke R, Abbas G, Pitanga A, Landreneau J, Awais O, Pennathur A, Ferson P, Christie N, Luketich J, Siegfried J, Wilson D, Landreneau R. The Hilar Stage IB-IIB Non-small Cell Lung Cancer: Differential Morbidity, Mortality, and Outcomes Between Lobectomy and Pneumonectomy Chest. 142: 51. DOI: 10.1378/Chest.1390665 |
0.451 |
|
| 2012 |
Gill RD, Williams S, Ostroff R, Brody E, Stewart A, Pass H, Rom W, Weissfeld JL, Siegfried J, Mehan M. Exposing the criminal record of every blood sample: Use of SOMAmer technology and sample mapping vectors to mitigate false biomarker discoveries in lung cancer. Journal of Clinical Oncology. 30: e21012-e21012. DOI: 10.1200/Jco.2012.30.15_Suppl.E21012 |
0.348 |
|
| 2012 |
Landreneau RJ, Abbas G, Awais O, Pennathur A, Siegfried J, Wilson DO, Luketich JD, Schuchert MJ. Factors influencing recurrence following anatomic lung resection for non-small cell lung cancer. Journal of Clinical Oncology. 30: 7074-7074. DOI: 10.1200/Jco.2012.30.15_Suppl.7074 |
0.469 |
|
| 2012 |
Schuchert MJ, Normolle DP, McCormick KN, Wilson DO, Siegfried J, Landreneau JP, Reamer M, Luketich JD, Landreneau RJ. Anatomic segmentectomy versus lobectomy for clinical stage I non-small cell lung cancer: A propensity-matched analysis. Journal of Clinical Oncology. 30: 7071-7071. DOI: 10.1200/Jco.2012.30.15_Suppl.7071 |
0.368 |
|
| 2012 |
Pancoska P, Romkes M, Nukui T, Buch S, Herazo-Maya J, Kaminski N, Dacic S, Weissfeld JL, Bigbee WL, Siegfried JM. Abstract 4937: Factors in NSCLC stage and outcome: Integrated genome-wide study Cancer Research. 72: 4937-4937. DOI: 10.1158/1538-7445.Am2012-4937 |
0.344 |
|
| 2012 |
Ng YK, Stabile LP, Torres SM, Supko KM, Lee J, Ho J, Berwick M, Siegfried JM. Abstract 3864: Biological basis of pan-ErbB receptor targeting for malignant melanoma treatment Cancer Research. 72: 3864-3864. DOI: 10.1158/1538-7445.Am2012-3864 |
0.41 |
|
| 2012 |
Casal RG, Parikh S, Saleet R, Basse P, Gibson M, Siegfried J, Levina V. Abstract 3461: C-kit inhibitors and radiation: A promising combination in NSCLC Cancer Research. 72: 3461-3461. DOI: 10.1158/1538-7445.Am2012-3461 |
0.532 |
|
| 2012 |
Romkes M, Nukui T, Buch S, Pancoska P, Herazo-Maya J, Kaminski N, Dacic S, Weissfeld JL, Bigbee WL, Shapiro SD, Siegfried JM. Abstract 1722: Prognostic markers in early stage non small-cell lung cancer (NSCLC) Cancer Research. 72: 1722-1722. DOI: 10.1158/1538-7445.Am2012-1722 |
0.44 |
|
| 2012 |
Pancoska P, Romkes M, Nukui T, Buch S, Herazo-Maya J, Kaminski N, Dacic S, Weissfeld JL, Bigbee WL, Shapiro SD, Siegfried JM. Abstract 1720: Validation of a 15-gene prognostic signature in stage IB non small-cell lung cancer (NSCLC) Cancer Research. 72: 1720-1720. DOI: 10.1158/1538-7445.Am2012-1720 |
0.375 |
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| 2012 |
Stabile LP, Rothstein ME, Lenzner D, Land SR, Dacic S, Siegfried JM. Abstract A39: Prevention of tobacco carcinogen-induced lung cancer in mice using antiestrogens Clinical Cancer Research. 18. DOI: 10.1158/1078-0432.12Aacriaslc-A39 |
0.543 |
|
| 2012 |
Gu S, Zheng Q, Siegfried JM, Pu J. Robust pulmonary lobe segmentation against incomplete fissures Proceedings of Spie. 8315: 831535. DOI: 10.1117/12.911073 |
0.366 |
|
| 2011 |
McLaughlin BT, Land S, Tarhini AA, Siegfried J, Argiris A. A phase II randomized trial of anastrozole (A) and fulvestrant (F) as consolidation therapy in postmenopausal women with advanced non-small cell lung cancer who have received first-line platinum-based chemotherapy with or without bevacizumab. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 29: TPS212. PMID 28023483 DOI: 10.1200/Jco.2011.29.15_Suppl.Tps212 |
0.467 |
|
| 2011 |
Garon EB, Dubinett SM, Kabbinavar FF, Reckamp KL, Marquez-Garban DC, Goodglick L, Sharma S, Stabile LP, Siegfried J, Pietras RJ. Randomized, multicenter phase II study of erlotinib (E) or E plus fulvestrant (F) in previously treated advanced non-small cell lung cancer (NSCLC). Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 29: TPS216. PMID 28023479 DOI: 10.1200/Jco.2011.29.15_Suppl.Tps216 |
0.418 |
|
| 2011 |
Nolen BM, Langmead CJ, Choi S, Lomakin A, Marrangoni A, Bigbee WL, Weissfeld JL, Wilson DO, Dacic S, Siegfried JM, Lokshin AE. Serum biomarker profiles as diagnostic tools in lung cancer. Cancer Biomarkers : Section a of Disease Markers. 10: 3-12. PMID 22297547 DOI: 10.3233/Cbm-2012-0229 |
0.399 |
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| 2011 |
Keohavong P, Kahkonen B, Kinchington E, Yin J, Jin J, Liu X, Siegfried JM, DI YP. K-ras mutations in lung tumors from NNK-treated mice with lipopolysaccharide-elicited lung inflammation. Anticancer Research. 31: 2877-82. PMID 21868532 |
0.376 |
|
| 2011 |
Xu H, Stabile LP, Gubish CT, Gooding WE, Grandis JR, Siegfried JM. Dual blockade of EGFR and c-Met abrogates redundant signaling and proliferation in head and neck carcinoma cells. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 17: 4425-38. PMID 21622718 DOI: 10.1158/1078-0432.Ccr-10-3339 |
0.401 |
|
| 2011 |
Horne ZD, Jack R, Gray ZT, Siegfried JM, Wilson DO, Yousem SA, Nason KS, Landreneau RJ, Luketich JD, Schuchert MJ. Increased levels of tumor-infiltrating lymphocytes are associated with improved recurrence-free survival in stage 1A non-small-cell lung cancer. The Journal of Surgical Research. 171: 1-5. PMID 21571304 DOI: 10.1016/J.Jss.2011.03.068 |
0.49 |
|
| 2011 |
Dulak AM, Gubish CT, Stabile LP, Henry C, Siegfried JM. HGF-independent potentiation of EGFR action by c-Met. Oncogene. 30: 3625-35. PMID 21423210 DOI: 10.1038/Onc.2011.84 |
0.735 |
|
| 2011 |
Zeng X, Hood BL, Zhao T, Conrads TP, Sun M, Gopalakrishnan V, Grover H, Day RS, Weissfeld JL, Wilson DO, Siegfried JM, Bigbee WL. Lung cancer serum biomarker discovery using label-free liquid chromatography-tandem mass spectrometry. Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. 6: 725-34. PMID 21304412 DOI: 10.1097/Jto.0B013E31820C312E |
0.508 |
|
| 2011 |
Stabile LP, Dacic S, Land SR, Lenzner DE, Dhir R, Acquafondata M, Landreneau RJ, Grandis JR, Siegfried JM. Combined analysis of estrogen receptor beta-1 and progesterone receptor expression identifies lung cancer patients with poor outcome. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 17: 154-64. PMID 21062926 DOI: 10.1158/1078-0432.Ccr-10-0992 |
0.475 |
|
| 2011 |
Horne ZD, Jack R, Gray ZT, Landreneau RJ, Siegfried JM, Wilson DO, Yousem SA, Nason KS, Luketich JD, Schuchert MJ. High Levels Of Tumor-infiltrating Lymphocytes And The Absence Of Angiolymphatic Invasion Increase Recurrence-free Survival In Stage 1A Non-Small Cell Lung Cancer Journal of Surgical Research. 165: 189-190. DOI: 10.1016/J.Jss.2010.11.615 |
0.467 |
|
| 2010 |
Stabile LP, Rothstein ME, Keohavong P, Lenzner D, Land SR, Gaither-Davis AL, Kim KJ, Kaminski N, Siegfried JM. Targeting of Both the c-Met and EGFR Pathways Results in Additive Inhibition of Lung Tumorigenesis in Transgenic Mice. Cancers. 2: 2153-70. PMID 21390244 DOI: 10.3390/Cancers2042153 |
0.564 |
|
| 2010 |
Ostroff RM, Bigbee WL, Franklin W, Gold L, Mehan M, Miller YE, Pass HI, Rom WN, Siegfried JM, Stewart A, Walker JJ, Weissfeld JL, Williams S, Zichi D, Brody EN. Unlocking biomarker discovery: large scale application of aptamer proteomic technology for early detection of lung cancer. Plos One. 5: e15003. PMID 21170350 DOI: 10.1038/Npre.2010.4537.1 |
0.459 |
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| 2010 |
Zeng X, Hood BL, Sun M, Conrads TP, Day RS, Weissfeld JL, Siegfried JM, Bigbee WL. Lung cancer serum biomarker discovery using glycoprotein capture and liquid chromatography mass spectrometry. Journal of Proteome Research. 9: 6440-9. PMID 20931982 DOI: 10.1021/Pr100696N |
0.392 |
|
| 2010 |
Ostrow KL, Hoque MO, Loyo M, Brait M, Greenberg A, Siegfried JM, Grandis JR, Davis AG, Bigbee WL, Rom W, Sidransky D. Molecular analysis of plasma DNA for the early detection of lung cancer by quantitative methylation-specific PCR Clinical Cancer Research. 16: 3463-3472. PMID 20592015 DOI: 10.1158/1078-0432.Ccr-09-3304 |
0.416 |
|
| 2010 |
Siegfried JM. Early changes in pulmonary gene expression following tobacco exposure shed light on the role of estrogen metabolism in lung carcinogenesis. Cancer Prevention Research (Philadelphia, Pa.). 3: 692-5. PMID 20515955 DOI: 10.1158/1940-6207.Capr-10-0093 |
0.404 |
|
| 2010 |
Schuchert MJ, Abbas G, Pennathur A, Ferson PF, Wilson DO, Siegfried JM, Luketich JD, Landreneau RJ. Anatomic Lung Resection for Clinical Stage I Non-small Cell Lung Cancer (NSCLC): Equivalent Outcomes Following Anatomic Segmentectomy and Lobectomy Chest. 138. DOI: 10.1378/Chest.10797 |
0.517 |
|
| 2010 |
Garon EB, Dubinett SM, Hosmer W, Reckamp KL, Kabbinavar FF, Goodglick L, Marquez-Garban DC, Stabile LP, Siegfried J, Pietras RJ. Randomized phase II study of erlotinib (E) alone or combined with fulvestrant (F) in previously treated patients with advanced non-small cell lung cancer (NSCLC). Journal of Clinical Oncology. 28: TPS295-TPS295. DOI: 10.1200/Jco.2010.28.15_Suppl.Tps295 |
0.41 |
|
| 2010 |
Nolen B, Lomakin A, Bigbee WL, Siegfried J, Lokshin A. Serum biomarkers for early detection of lung cancer. Journal of Clinical Oncology. 28: e21057-e21057. DOI: 10.1200/Jco.2010.28.15_Suppl.E21057 |
0.466 |
|
| 2010 |
Brenda D, Buch S, Nukui T, Day R, Siegfried J, Weissfeld J, Romkes M. Abstract LB-414: Variation in base excision repair genes and risk of smoking-related non-small cell lung cancer Cancer Research. 70. DOI: 10.1158/1538-7445.Am10-Lb-414 |
0.31 |
|
| 2010 |
Bigbee WL, Gopalakrishnan V, Dacic S, Hauskrecht M, Weissfeld JL, Wilson DO, Siegfried JM, Lokshin AE. Abstract LB-210: A multiplexed serum biomarker immunoassay panel discriminates clinical lung cancer patients from cancer-free high-risk subjects in a CT-screened cohort Cancer Research. 70. DOI: 10.1158/1538-7445.Am10-Lb-210 |
0.473 |
|
| 2010 |
Siegfried JM, Rothstein ME, Lenzner D, Gubish CT, Land SR, Stabile LP. Abstract LB-180: Prevention of NNK-induced lung cancer in mice by anti-estrogen therapy Cancer Research. 70. DOI: 10.1158/1538-7445.Am10-Lb-180 |
0.403 |
|
| 2010 |
Egloff AM, Kelly L, Panelli M, Davis AG, Siegfried JM, Grandis JR, Argiris A. Abstract 4661: Decreased epidermal growth factor receptor plasma levels as an indicator for head and neck squamous cell carcinoma case status and disease progression Cancer Research. 70: 4661-4661. DOI: 10.1158/1538-7445.Am10-4661 |
0.406 |
|
| 2010 |
Zeng X, Hood BL, Zhao T, Conrads TP, Sun M, Day RS, Gopalakrishnan V, Grover H, Weissfeld JL, Siegfried JM, Bigbee WL. Abstract 4564: Lung cancer serum biomarker discovery using label free LC-MS/MS Cancer Research. 70: 4564-4564. DOI: 10.1158/1538-7445.Am10-4564 |
0.46 |
|
| 2010 |
Keohavong P, Kahkonen B, Kinchington E, Yin J, Jin J, Siegfried JM, Di P. Abstract 4377: Pulmonary inflammation and lung tumorigenesis in mice Cancer Research. 70: 4377-4377. DOI: 10.1158/1538-7445.Am10-4377 |
0.453 |
|
| 2010 |
Dulak AM, Gubish CT, Siegfried JM. Abstract 4123: Induction of motility, invasion, and proliferation by wild-type EGFR depends on c-Met in NSCLC Cancer Research. 70: 4123-4123. DOI: 10.1158/1538-7445.Am10-4123 |
0.771 |
|
| 2010 |
Stabile LP, Dacic S, Land SR, Lenzner D, Dhir R, Aquafondata M, Landreneau RJ, Siegfried JM. Abstract 3667: ERβ and PR expression show opposite effects on survival in NSCLC with no sex differences Cancer Research. 70: 3667-3667. DOI: 10.1158/1538-7445.Am10-3667 |
0.508 |
|
| 2010 |
Gubish CT, Stabile LP, Davis C, Rothstein ME, Siegfried JM. Abstract 3483: Combining the multi-targeted tyrosine kinase inhibitor, vandetanib, with fulvestrant results in enhanced anti-tumorigenic effects for lung cancer Cancer Research. 70: 3483-3483. DOI: 10.1158/1538-7445.Am10-3483 |
0.545 |
|
| 2009 |
Egloff A, Feinstein TM, Joyce SC, Kelly LA, Panelli MC, Yang T, Siegfried JM, Grandis JR, Argiris A. Blood biomarker modulation with dasatinib (D) and cetuximab (C) in patients (pts) with advanced solid malignancies. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 27: 6034. PMID 27961909 DOI: 10.1200/Jco.2009.27.15_Suppl.6034 |
0.361 |
|
| 2009 |
Siegfried JM, Hershberger PA, Stabile LP. Estrogen receptor signaling in lung cancer. Seminars in Oncology. 36: 524-31. PMID 19995644 DOI: 10.1053/J.Seminoncol.2009.10.004 |
0.523 |
|
| 2009 |
Egloff AM, Rothstein ME, Seethala R, Siegfried JM, Grandis JR, Stabile LP. Cross-talk between estrogen receptor and epidermal growth factor receptor in head and neck squamous cell carcinoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 15: 6529-40. PMID 19825947 DOI: 10.1158/1078-0432.Ccr-09-0862 |
0.35 |
|
| 2009 |
Yue W, Sun Q, Landreneau R, Wu C, Siegfried JM, Yu J, Zhang L. Fibulin-5 suppresses lung cancer invasion by inhibiting matrix metalloproteinase-7 expression. Cancer Research. 69: 6339-46. PMID 19584278 DOI: 10.1158/0008-5472.Can-09-0398 |
0.509 |
|
| 2009 |
Knowles LM, Stabile LP, Egloff AM, Rothstein ME, Thomas SM, Gubish CT, Lerner EC, Seethala RR, Suzuki S, Quesnelle KM, Morgan S, Ferris RL, Grandis JR, Siegfried JM. HGF and c-Met participate in paracrine tumorigenic pathways in head and neck squamous cell cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 15: 3740-50. PMID 19470725 DOI: 10.1158/1078-0432.Ccr-08-3252 |
0.38 |
|
| 2009 |
Hershberger PA, Stabile LP, Kanterewicz B, Rothstein ME, Gubish CT, Land S, Shuai Y, Siegfried JM, Nichols M. Estrogen receptor beta (ERbeta) subtype-specific ligands increase transcription, p44/p42 mitogen activated protein kinase (MAPK) activation and growth in human non-small cell lung cancer cells. The Journal of Steroid Biochemistry and Molecular Biology. 116: 102-9. PMID 19460433 DOI: 10.1016/J.Jsbmb.2009.05.004 |
0.427 |
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| 2009 |
Traynor AM, Schiller JH, Stabile LP, Kolesar JM, Eickhoff JC, Dacic S, Hoang T, Dubey S, Marcotte SM, Siegfried JM. Pilot study of gefitinib and fulvestrant in the treatment of post-menopausal women with advanced non-small cell lung cancer. Lung Cancer (Amsterdam, Netherlands). 64: 51-9. PMID 18701186 DOI: 10.1016/J.Lungcan.2008.07.002 |
0.547 |
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| 2008 |
Zhang W, Bhola N, Kalyankrishna S, Gooding W, Hunt J, Seethala R, Grandis JR, Siegfried JM. Kinin b2 receptor mediates induction of cyclooxygenase-2 and is overexpressed in head and neck squamous cell carcinomas. Molecular Cancer Research : McR. 6: 1946-56. PMID 19074839 DOI: 10.1158/1541-7786.Mcr-07-2197 |
0.417 |
|
| 2008 |
Stabile LP, Rothstein ME, Keohavong P, Jin J, Yin J, Land SR, Dacic S, Luong TM, Kim KJ, Dulak AM, Siegfried JM. Therapeutic targeting of human hepatocyte growth factor with a single neutralizing monoclonal antibody reduces lung tumorigenesis. Molecular Cancer Therapeutics. 7: 1913-22. PMID 18645002 DOI: 10.1158/1535-7163.Mct-07-2169 |
0.758 |
|
| 2008 |
Wilson DO, Weissfeld JL, Fuhrman CR, Fisher SN, Balogh P, Landreneau RJ, Luketich JD, Siegfried JM. The Pittsburgh Lung Screening Study (PLuSS): outcomes within 3 years of a first computed tomography scan. American Journal of Respiratory and Critical Care Medicine. 178: 956-61. PMID 18635890 DOI: 10.1164/Rccm.200802-336Oc |
0.389 |
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| 2008 |
Koppikar P, Choi SH, Egloff AM, Cai Q, Suzuki S, Freilino M, Nozawa H, Thomas SM, Gooding WE, Siegfried JM, Grandis JR. Combined inhibition of c-Src and epidermal growth factor receptor abrogates growth and invasion of head and neck squamous cell carcinoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 14: 4284-91. PMID 18594011 DOI: 10.1158/1078-0432.Ccr-07-5226 |
0.437 |
|
| 2008 |
Wilson DO, Weissfeld JL, Balkan A, Schragin JG, Fuhrman CR, Fisher SN, Wilson J, Leader JK, Siegfried JM, Shapiro SD, Sciurba FC. Association of radiographic emphysema and airflow obstruction with lung cancer. American Journal of Respiratory and Critical Care Medicine. 178: 738-44. PMID 18565949 DOI: 10.1164/Rccm.200803-435Oc |
0.494 |
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| 2008 |
Seethala RR, Gooding WE, Handler PN, Collins B, Zhang Q, Siegfried JM, Grandis JR. Immunohistochemical analysis of phosphotyrosine signal transducer and activator of transcription 3 and epidermal growth factor receptor autocrine signaling pathways in head and neck cancers and metastatic lymph nodes. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 14: 1303-9. PMID 18316548 DOI: 10.1158/1078-0432.Ccr-07-1543 |
0.379 |
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| 2008 |
Yue W, Sun Q, Dacic S, Landreneau RJ, Siegfried JM, Yu J, Zhang L. Downregulation of Dkk3 activates beta-catenin/TCF-4 signaling in lung cancer. Carcinogenesis. 29: 84-92. PMID 18048388 DOI: 10.1093/Carcin/Bgm267 |
0.509 |
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| 2008 |
Romkes M, Landreneau RJ, Schuchert MJ, Buch SC, Luketich JD, Siegfried JM. Use of ERCC1 polymorphism and extreme drug resistance assay to predict overall non-small cell lung cancer survival and responsiveness to platinum-based chemotherapy agents Journal of Clinical Oncology. 26: 8092-8092. DOI: 10.1200/Jco.2008.26.15_Suppl.8092 |
0.395 |
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| 2008 |
Garon EB, Sadeghi S, Kabbinavar FF, Reckamp KL, Marquez-Garban DC, Stabile LP, Goodglick L, Dubinett SM, Siegfried JM, Pietras RJ. Interim safety analysis of a phase II study of erlotinib (E) alone or combined with fulvestrant (F) in previously treated patients with advanced non-small cell lung cancer (NSCLC) Journal of Clinical Oncology. 26: 19091-19091. DOI: 10.1200/Jco.2008.26.15_Suppl.19091 |
0.432 |
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| 2007 |
Yildiz PB, Shyr Y, Rahman JS, Wardwell NR, Zimmerman LJ, Shakhtour B, Gray WH, Chen S, Li M, Roder H, Liebler DC, Bigbee WL, Siegfried JM, Weissfeld JL, Gonzalez AL, et al. Diagnostic accuracy of MALDI mass spectrometric analysis of unfractionated serum in lung cancer. Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. 2: 893-901. PMID 17909350 DOI: 10.1097/Jto.0B013E31814B8Be7 |
0.429 |
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| 2007 |
Yue W, Dacic S, Sun Q, Landreneau R, Guo M, Zhou W, Siegfried JM, Yu J, Zhang L. Frequent inactivation of RAMP2, EFEMP1 and Dutt1 in lung cancer by promoter hypermethylation. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 13: 4336-44. PMID 17671114 DOI: 10.1158/1078-0432.Ccr-07-0015 |
0.513 |
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| 2007 |
Siegfried JM, Gubish CT, Rothstein ME, Queiroz de Oliveira PE, Stabile LP. Signaling pathways involved in cyclooxygenase-2 induction by hepatocyte growth factor in non small-cell lung cancer. Molecular Pharmacology. 72: 769-79. PMID 17550984 DOI: 10.1124/Mol.107.034215 |
0.496 |
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| 2007 |
Bigbee WL, Grandis JR, Siegfried JM. Multiple cytokine and growth factor serum biomarkers predict therapeutic response and survival in advanced-stage head and neck cancer patients. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 13: 3107-8. PMID 17545511 DOI: 10.1158/1078-0432.Ccr-07-0746 |
0.322 |
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| 2007 |
Liu Y, Gao W, Siegfried JM, Weissfeld JL, Luketich JD, Keohavong P. Promoter methylation of RASSF1A and DAPK and mutations of K-ras, p53, and EGFR in lung tumors from smokers and never-smokers. Bmc Cancer. 7: 74. PMID 17477876 DOI: 10.1186/1471-2407-7-74 |
0.503 |
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| 2007 |
Zhang Q, Bhola NE, Lui VW, Siwak DR, Thomas SM, Gubish CT, Siegfried JM, Mills GB, Shin D, Grandis JR. Antitumor mechanisms of combined gastrin-releasing peptide receptor and epidermal growth factor receptor targeting in head and neck cancer. Molecular Cancer Therapeutics. 6: 1414-24. PMID 17431120 DOI: 10.1158/1535-7163.Mct-06-0678 |
0.452 |
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| 2007 |
Liu X, Carlisle DL, Swick MC, Gaither-Davis A, Grandis JR, Siegfried JM. Gastrin-releasing peptide activates Akt through the epidermal growth factor receptor pathway and abrogates the effect of gefitinib. Experimental Cell Research. 313: 1361-72. PMID 17349623 DOI: 10.1016/J.Yexcr.2007.01.016 |
0.457 |
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| 2007 |
Linkov F, Lisovich A, Yurkovetsky Z, Marrangoni A, Velikokhatnaya L, Nolen B, Winans M, Bigbee W, Siegfried J, Lokshin A, Ferris RL. Early detection of head and neck cancer: development of a novel screening tool using multiplexed immunobead-based biomarker profiling. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 16: 102-7. PMID 17220337 DOI: 10.1158/1055-9965.Epi-06-0602 |
0.365 |
|
| 2007 |
Zhang W, Weissfeld JL, Romkes M, Land SR, Grandis JR, Siegfried JM. Association of the EGFR intron 1 CA repeat length with lung cancer risk. Molecular Carcinogenesis. 46: 372-80. PMID 17219440 DOI: 10.1002/Mc.20285 |
0.504 |
|
| 2007 |
Carlisle DL, Liu X, Hopkins TM, Swick MC, Dhir R, Siegfried JM. Nicotine activates cell-signaling pathways through muscle-type and neuronal nicotinic acetylcholine receptors in non-small cell lung cancer cells. Pulmonary Pharmacology & Therapeutics. 20: 629-41. PMID 17015027 DOI: 10.1016/J.Pupt.2006.07.001 |
0.421 |
|
| 2006 |
Zhang W, Stabile LP, Keohavong P, Romkes M, Grandis JR, Traynor AM, Siegfried JM. Mutation and polymorphism in the EGFR-TK domain associated with lung cancer. Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. 1: 635-47. PMID 17409930 |
0.417 |
|
| 2006 |
Thomas SM, Bhola NE, Zhang Q, Contrucci SC, Wentzel AL, Freilino ML, Gooding WE, Siegfried JM, Chan DC, Grandis JR. Cross-talk between G protein-coupled receptor and epidermal growth factor receptor signaling pathways contributes to growth and invasion of head and neck squamous cell carcinoma. Cancer Research. 66: 11831-9. PMID 17178880 DOI: 10.1158/0008-5472.Can-06-2876 |
0.443 |
|
| 2006 |
Gao WM, Romkes M, Siegfried JM, Luketich JD, Keohavong P. Polymorphisms in DNA repair genes XPD and XRCC1 and p53 mutations in lung carcinomas of never-smokers. Molecular Carcinogenesis. 45: 828-32. PMID 16865671 DOI: 10.1002/Mc.20208 |
0.438 |
|
| 2006 |
Dubey S, Siegfried JM, Traynor AM. Non-small-cell lung cancer and breast carcinoma: chemotherapy and beyond. The Lancet. Oncology. 7: 416-24. PMID 16648046 DOI: 10.1016/S1470-2045(06)70693-3 |
0.518 |
|
| 2006 |
Zhang Q, Thomas SM, Lui VW, Xi S, Siegfried JM, Fan H, Smithgall TE, Mills GB, Grandis JR. Phosphorylation of TNF-alpha converting enzyme by gastrin-releasing peptide induces amphiregulin release and EGF receptor activation. Proceedings of the National Academy of Sciences of the United States of America. 103: 6901-6. PMID 16641105 DOI: 10.1073/Pnas.0509719103 |
0.384 |
|
| 2006 |
Liu Y, Lan Q, Siegfried JM, Luketich JD, Keohavong P. Aberrant promoter methylation of p16 and MGMT genes in lung tumors from smoking and never-smoking lung cancer patients. Neoplasia (New York, N.Y.). 8: 46-51. PMID 16533425 DOI: 10.1593/Neo.05586 |
0.428 |
|
| 2006 |
Stabile LP, Lyker JS, Land SR, Dacic S, Zamboni BA, Siegfried JM. Transgenic mice overexpressing hepatocyte growth factor in the airways show increased susceptibility to lung cancer. Carcinogenesis. 27: 1547-55. PMID 16513678 DOI: 10.1093/Carcin/Bgl003 |
0.513 |
|
| 2006 |
Siegfried JM. Hormone replacement therapy and decreased lung cancer survival. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 24: 9-10. PMID 16314612 DOI: 10.1200/Jco.2005.04.2531 |
0.537 |
|
| 2006 |
Oton AB, Belani C, Cai C, Owonikoko T, Gooding W, Siegfried J, Ramalingam S. Comparison of survival for non-small cell lung cancer (NSCLC) between premenopausal and postmenopausal women: An analysis of the National Surveillance, Epidemiology and End Results (SEER) Database Journal of Clinical Oncology. 24: 7038-7038. DOI: 10.1200/Jco.2006.24.18_Suppl.7038 |
0.516 |
|
| 2006 |
Zhang W, Stabile LP, Keohavong P, Romkes M, Grandis JR, Traynor AM, Siegfried JM. Mutation and Polymorphism in the EGFR-TK Domain Associated with Lung Cancer Journal of Thoracic Oncology. 1: 635-647. DOI: 10.1016/S1556-0864(15)30375-0 |
0.487 |
|
| 2005 |
Traynor AM, Schiller JH, Stabile LP, Kolesar JM, Belani CP, Hoang T, Dubey S, Eickhoff J, Marcotte SM, Siegfried JM. Combination therapy with gefitinib and fulvestrant (G/F) for women with non-small cell lung cancer (NSCLC). Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 23: 7224. PMID 27944717 DOI: 10.1200/Jco.2005.23.16_Suppl.7224 |
0.508 |
|
| 2005 |
Zeh HJ, Winikoff S, Landsittel DP, Gorelik E, Marrangoni AM, Velikokhatnaya L, Winans MT, Lee K, Moser A, Bartlett D, Lotze MT, Siegfried JM, Whitcomb D, Papacristou G, Slivka A, et al. Multianalyte profiling of serum cytokines for detection of pancreatic cancer. Cancer Biomarkers : Section a of Disease Markers. 1: 259-69. PMID 17192050 DOI: 10.3233/Cbm-2005-1601 |
0.329 |
|
| 2005 |
Thomas SM, Grandis JR, Wentzel AL, Gooding WE, Lui VW, Siegfried JM. Gastrin-releasing peptide receptor mediates activation of the epidermal growth factor receptor in lung cancer cells. Neoplasia (New York, N.Y.). 7: 426-31. PMID 15967120 DOI: 10.1593/Neo.04454 |
0.512 |
|
| 2005 |
Hershberger PA, Vasquez AC, Kanterewicz B, Land S, Siegfried JM, Nichols M. Regulation of endogenous gene expression in human non-small cell lung cancer cells by estrogen receptor ligands. Cancer Research. 65: 1598-605. PMID 15735050 DOI: 10.1158/0008-5472.Can-04-2694 |
0.48 |
|
| 2005 |
Stabile LP, Lyker JS, Gubish CT, Zhang W, Grandis JR, Siegfried JM. Combined targeting of the estrogen receptor and the epidermal growth factor receptor in non-small cell lung cancer shows enhanced antiproliferative effects. Cancer Research. 65: 1459-70. PMID 15735034 DOI: 10.1158/0008-5472.Can-04-1872 |
0.526 |
|
| 2005 |
Belani C, Fuhrman C, Wilson D, Fisher S, Sciurba F, Luketich J, Weissfeld J, Siegfried J. P-238 Two-year outcomes from lung cancer screening with low-dose helical computed tomography Lung Cancer. 49: S177. DOI: 10.1016/S0169-5002(05)80732-9 |
0.4 |
|
| 2005 |
Dubey S, Siegfried J, Stabile L, Kolesar J, Belani C, Hoang T, Eickhoff J, Marcotte S, Schiller J, Traynor A. PD-071 Combination therapy with gefitinib and fulvestrant (G/F) forwomen with non-small cell lung cancer (NSCLC) Lung Cancer. 49. DOI: 10.1016/S0169-5002(05)80404-0 |
0.442 |
|
| 2005 |
Siegfried JM. E57. Estrogen receptor epidermal growth factor receptor interactions in lung cancer Lung Cancer. 49. DOI: 10.1016/S0169-5002(05)80120-5 |
0.453 |
|
| 2005 |
Niu Y, Stabile L, Epperly MW, Siegfried J, Greenberger JS. 729. C-Met Antisense Plasmid Liposome Complex Increases Radiation Sensitivity of Lung Tumor Cells In Vivo or In Vitro Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.07.269 |
0.449 |
|
| 2004 |
Carlisle DL, Hopkins TM, Gaither-Davis A, Silhanek MJ, Luketich JD, Christie NA, Siegfried JM. Nicotine signals through muscle-type and neuronal nicotinic acetylcholine receptors in both human bronchial epithelial cells and airway fibroblasts. Respiratory Research. 5: 27. PMID 15588326 DOI: 10.1186/1465-9921-5-27 |
0.33 |
|
| 2004 |
Zhang Q, Thomas SM, Xi S, Smithgall TE, Siegfried JM, Kamens J, Gooding WE, Grandis JR. SRC family kinases mediate epidermal growth factor receptor ligand cleavage, proliferation, and invasion of head and neck cancer cells. Cancer Research. 64: 6166-73. PMID 15342401 DOI: 10.1158/0008-5472.Can-04-0504 |
0.378 |
|
| 2004 |
Stabile LP, Siegfried JM. Estrogen receptor pathways in lung cancer. Current Oncology Reports. 6: 259-67. PMID 15161576 DOI: 10.1007/S11912-004-0033-2 |
0.54 |
|
| 2004 |
Siegfried JM, Luketich JD, Stabile LP, Christie N, Land SR. Elevated hepatocyte growth factor level correlates with poor outcome in early-stage and late-stage adenocarcinoma of the lung. Chest. 125: 116S-9S. PMID 15136456 DOI: 10.1378/Chest.125.5_Suppl.116S |
0.382 |
|
| 2004 |
Gao WM, Romkes M, Siegfried JM, Luketich JD, Keohavong P. No association between the XPD 312, 751, or XRCC1 399 polymorphisms and K-ras gene mutation in smoking non-small-cell lung cancer. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 13: 673-5. PMID 15066937 |
0.318 |
|
| 2004 |
Stabile LP, Lyker JS, Huang L, Siegfried JM. Inhibition of human non-small cell lung tumors by a c-Met antisense/U6 expression plasmid strategy. Gene Therapy. 11: 325-35. PMID 14737093 DOI: 10.1038/Sj.Gt.3302169 |
0.497 |
|
| 2003 |
Makarenkova VP, Shurin GV, Tourkova IL, Balkir L, Pirtskhalaishvili G, Perez L, Gerein V, Siegfried JM, Shurin MR. Lung cancer-derived bombesin-like peptides down-regulate the generation and function of human dendritic cells. Journal of Neuroimmunology. 145: 55-67. PMID 14644031 DOI: 10.1016/J.Jneuroim.2003.09.009 |
0.381 |
|
| 2003 |
Lui VW, Thomas SM, Zhang Q, Wentzel AL, Siegfried JM, Li JY, Grandis JR. Mitogenic effects of gastrin-releasing peptide in head and neck squamous cancer cells are mediated by activation of the epidermal growth factor receptor. Oncogene. 22: 6183-93. PMID 13679857 DOI: 10.1038/Sj.Onc.1206720 |
0.425 |
|
| 2003 |
Gao WM, Romkes M, Day RD, Siegfried JM, Luketich JD, Mady HH, Melhem MF, Keohavong P. Association of the DNA repair gene XPD Asp312Asn polymorphism with p53 gene mutations in tobacco-related non-small cell lung cancer. Carcinogenesis. 24: 1671-6. PMID 12844488 DOI: 10.1093/Carcin/Bgg115 |
0.415 |
|
| 2003 |
Gao WM, Mady HH, Yu GY, Siegfried JM, Luketich JD, Melhem MF, Keohavong P. Comparison of p53 mutations between adenocarcinoma and squamous cell carcinoma of the lung: unique spectra involving G to A transitions and G to T transversions in both histologic types. Lung Cancer (Amsterdam, Netherlands). 40: 141-50. PMID 12711114 DOI: 10.1016/S0169-5002(03)00035-7 |
0.412 |
|
| 2003 |
Siegfried JM, Stabile L, Lerdtragool S, Romkes M. E-73.Hormones - do they make a difference in lung cancer? Lung Cancer. 41. DOI: 10.1016/S0169-5002(03)90480-6 |
0.479 |
|
| 2002 |
Stabile LP, Davis AL, Gubish CT, Hopkins TM, Luketich JD, Christie N, Finkelstein S, Siegfried JM. Human non-small cell lung tumors and cells derived from normal lung express both estrogen receptor alpha and beta and show biological responses to estrogen. Cancer Research. 62: 2141-50. PMID 11929836 |
0.374 |
|
| 2002 |
Lango MN, Dyer KF, Lui VW, Gooding WE, Gubish C, Siegfried JM, Grandis JR. Gastrin-releasing peptide receptor-mediated autocrine growth in squamous cell carcinoma of the head and neck. Journal of the National Cancer Institute. 94: 375-83. PMID 11880476 DOI: 10.1093/Jnci/94.5.375 |
0.405 |
|
| 2001 |
Siegfried JM. Women and lung cancer: does oestrogen play a role? Lancet Oncology. 2: 506-513. PMID 11905727 DOI: 10.1016/S1470-2045(01)00457-0 |
0.482 |
|
| 2001 |
Keohavong P, Mady HH, Gao WM, Siegfried JM, Luketich JD, Melhem MF. Topographic analysis of K-ras mutations in histologically normal lung tissues and tumours of lung cancer patients British Journal of Cancer. 85: 235-241. PMID 11461083 DOI: 10.1054/Bjoc.2001.1913 |
0.395 |
|
| 2001 |
Pilewski JM, Bumbalo TS, Davis AG, Siegfried JM. Hepatocyte growth factor promotes tumor growth in a novel in vivo model of human lung cancer. American Journal of Respiratory Cell and Molecular Biology. 24: 556-562. PMID 11350824 DOI: 10.1165/Ajrcmb.24.5.4074 |
0.527 |
|
| 2000 |
Weigel TL, Yousem S, Dacic S, Kosco PJ, Siegfried J, Luketich JD. Fluorescence bronchoscopic surveillance after curative surgical resection for non-small-cell lung cancer. Annals of Surgical Oncology. 7: 176-180. PMID 10791846 DOI: 10.1007/Bf02523650 |
0.482 |
|
| 2000 |
Shriver SP, Bourdeau HA, Gubish CT, Tirpak DL, Davis AL, Luketich JD, Siegfried JM. Sex-specific expression of gastrin-releasing peptide receptor: relationship to smoking history and risk of lung cancer. Journal of the National Cancer Institute. 92: 24-33. PMID 10620630 DOI: 10.1093/Jnci/92.1.24 |
0.342 |
|
| 1999 |
Siegfried JM. Lung cancer screening in high-risk populations. Clinical Lung Cancer. 1: 100-106. PMID 14733655 DOI: 10.3816/Clc.1999.N.007 |
0.474 |
|
| 1999 |
Siegfried JM, Krishnamachary N, Davis AG, Gubish C, Hunt JD, Shriver SP. Evidence for Autocrine Actions of Neuromedin B and Gastrin-releasing Peptide in Non-small Cell Lung Cancer Pulmonary Pharmacology & Therapeutics. 12: 291-302. PMID 10545285 DOI: 10.1006/Pupt.1999.0210 |
0.407 |
|
| 1999 |
Schwartz AG, Siegfried JM, Weiss L. Familial aggregation of breast cancer with early onset lung cancer Genetic Epidemiology. 17: 274-284. PMID 10520210 DOI: 10.1002/(Sici)1098-2272(199911)17:4<274::Aid-Gepi3>3.0.Co;2-A |
0.432 |
|
| 1998 |
Siegfried JM, Weissfeld LA, Luketich JD, Weyant RJ, Gubish CT, Landreneau RJ. The clinical significance of hepatocyte growth factor for non-small cell lung cancer Annals of Thoracic Surgery. 66: 1915-1918. PMID 9930468 DOI: 10.1016/S0003-4975(98)01165-5 |
0.501 |
|
| 1998 |
Shriver SP, Shriver MD, Tirpak DL, Bloch LM, Hunt JD, Ferrell RE, Siegfried JM. Trinucleotide repeat length variation in the human ribosomal protein L14 gene (RPL14): localization to 3p21.3 and loss of heterozygosity in lung and oral cancers. Mutation Research. 406: 9-23. PMID 9920051 DOI: 10.1016/S1383-5726(98)00006-5 |
0.505 |
|
| 1998 |
Feder M, Siegfried JM, Balshem A, Litwin S, Keller SM, Liu Z, Testa JR. Clinical relevance of chromosome abnormalities in non-small cell lung cancer. Cancer Genetics and Cytogenetics. 102: 25-31. PMID 9530336 DOI: 10.1016/S0165-4608(97)00274-4 |
0.388 |
|
| 1998 |
Siegfried JM. Biology and chemoprevention of lung cancer. Chest. 113: 40. PMID 9438689 DOI: 10.1378/Chest.113.1_Supplement.40S |
0.499 |
|
| 1998 |
Resnick NM, Clarke MR, Siegfried JM, Landreneau R, Asman DC, Ge L, Kierstead LS, Dougherty GD, Cooper DL. Expression of the Cell Adhesion Molecule CD44 in Human Lung Tumors and Cell Lines. Molecular Diagnosis. 3: 93-103. DOI: 10.1016/S1084-8592(98)80057-X |
0.44 |
|
| 1997 |
Taguchi T, Cheng GZ, Bell DW, Balsara B, Liu Z, Siegfried JM, Testa JR. Combined chromosome microdissection and comparative genomic hybridization detect multiple sites of amplified DNA in a human lung carcinoma cell line Genes Chromosomes and Cancer. 20: 208-212. PMID 9331573 DOI: 10.1002/(Sici)1098-2264(199710)20:2<208::Aid-Gcc13>3.0.Co;2-M |
0.369 |
|
| 1997 |
Siegfried JM, DeMICHELE MAA, Hunt JD, Davis AG, Vohra KP, Pilewski JM. Expression of mRNA for gastrin-releasing peptide receptor by human bronchial epithelial cells. Association with prolonged tobacco exposure and responsiveness to bombesin-like peptides. American Journal of Respiratory and Critical Care Medicine. 156: 358-366. PMID 9279210 DOI: 10.1164/Ajrccm.156.2.9608047 |
0.416 |
|
| 1997 |
Keohavong P, Zhu D, Whiteside TL, Swalsky P, Bakker A, Elder EM, Siegfried JM, Srivastava S, Finkelstein SD. Detection of infrequent and multiple K-ras mutations in human tumors and tumor-adjacent tissues. Analytical Biochemistry. 247: 394-403. PMID 9177704 DOI: 10.1006/Abio.1997.2100 |
0.374 |
|
| 1997 |
Keohavong P, Zhu D, Melacrinos AC, Demichele MAA, Weyant RJ, Luketich JD, Testa JR, Fedder M, Siegfried JM. Detection of low-fraction K-ras mutations in primary lung tumors using a sensitive method International Journal of Cancer. 74: 162-170. PMID 9133449 DOI: 10.1002/(Sici)1097-0215(19970422)74:2<162::Aid-Ijc4>3.0.Co;2-X |
0.337 |
|
| 1995 |
Hunt JD, Testa JR, McCallister DF, Smith DI, Hutchinson J, Campbell WC, Siegfried JM. Evidence for a tumor suppressor gene on chromosome 3 in human non-small cell lung carcinoma Cancer Genetics and Cytogenetics. 84: 154. DOI: 10.1016/0165-4608(96)85304-0 |
0.441 |
|
| 1994 |
Hunt JD, Pippin BA, Landreneau RJ, Jacob WF, Lotze MT, Siegfried JM. Transfer and expression of the human interleukin-4 gene in carcinoma and stromal cell lines derived from lung cancer patients. Journal of Immunotherapy With Emphasis On Tumor Immunology : Official Journal of the Society For Biological Therapy. 14: 314-21. PMID 8280714 DOI: 10.1097/00002371-199311000-00011 |
0.344 |
|
| 1994 |
DeMichele MA, Davis AL, Hunt JD, Landreneau RJ, Siegfried JM. Expression of mRNA for three bombesin receptor subtypes in human bronchial epithelial cells American Journal of Respiratory Cell and Molecular Biology. 11: 66-74. PMID 8018339 DOI: 10.1165/Ajrcmb.11.1.8018339 |
0.397 |
|
| 1994 |
Siegfried JM, Davis AL, Testa JR, Hunt JD, Keenan RJ, Yousem SA, Ritter PS, Ferson PF, Landreneau RJ. Ability to culture resectable non-small cell lung carcinomas is correlated with recurrence. The Annals of Thoracic Surgery. 58: 662-6; discussion 66. PMID 7944686 DOI: 10.1016/0003-4975(94)90724-2 |
0.53 |
|
| 1993 |
Siegfried JM, Guentert PJ, Gaither AL. Effects of bombesin and gastrin-releasing peptide on human bronchial epithelial cells from a series of donors: individual variation and modulation by bombesin analogs. Anatomical Record-Advances in Integrative Anatomy and Evolutionary Biology. 236: 241-247. PMID 8507011 DOI: 10.1002/Ar.1092360129 |
0.365 |
|
| 1993 |
Zhou Jy, Taguchi T, Siegfried JM, Jhanwar SC, Resau J, Testa JR. Characterization of 9q;15q whole-arm translocation derivatives in non-small cell lung carcinomas by fluorescence in situ hybridization. Cancer Genetics and Cytogenetics. 69: 1-6. PMID 8397063 DOI: 10.1016/0165-4608(93)90102-R |
0.365 |
|
| 1993 |
Siegfried JM, Hunt JD, Zhou JY, Keller SM, Testa JR. Cytogenetic abnormalities in non-small cell lung carcinoma: similarity of findings in conventional and feeder cell layer cultures. Genes, Chromosomes & Cancer. 6: 30-8. PMID 7680219 DOI: 10.1002/Gcc.2870060107 |
0.36 |
|
| 1992 |
Siegfried JM, Kasprzyk PG, Treston AM, Mulshine JL, Quinn KA, Cuttitta F. A mitogenic peptide amide encoded within the E peptide domain of the insulin-like growth factor IB prohormone Proceedings of the National Academy of Sciences of the United States of America. 89: 8107-8111. PMID 1325646 DOI: 10.1073/Pnas.89.17.8107 |
0.305 |
|
| 1991 |
Siegfried J, Ellison D, Miura I, Resau J, Testa J. Cells cultured from non-small cell lung carcinomas are representative of solid tumor tissue based on cytogenetic evidence Cancer Genetics and Cytogenetics. 56: 137. DOI: 10.1016/0165-4608(91)90448-4 |
0.452 |
|
| 1990 |
Andrews PG, Owens SE, Siegfried JM. Induction of micronuclei in cultured human bronchial epithelial cells by direct-acting carcinogens. Toxicology in Vitro. 4: 735-742. PMID 20702159 DOI: 10.1016/0887-2333(90)90042-R |
0.334 |
|
| 1990 |
Miura I, Siegfried JM, Resau J, Keller SM, Zhou JY, Testa JR. Chromosome alterations in 21 non-small cell lung carcinomas Genes Chromosomes and Cancer. 2: 328-338. PMID 2176544 DOI: 10.1002/Gcc.2870020411 |
0.363 |
|
| 1989 |
Siegfried JM. Culture of primary lung tumors using medium conditioned by a lung carcinoma cell line. Journal of Cellular Biochemistry. 41: 91-95. PMID 2559086 DOI: 10.1002/Jcb.240410205 |
0.434 |
|
| 1984 |
Siegfried JM, Nesnow S. Cytotoxicity of chemical carcinogens towards human bronchial epithelial cells evaluated in a clonal assay Carcinogenesis. 5: 1317-1322. PMID 6435898 DOI: 10.1093/Carcin/5.10.1317 |
0.345 |
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