Michael B. Jarstfer

Affiliations: 
Medicinal Chemistry and Natural Products University of North Carolina, Chapel Hill, Chapel Hill, NC 
Website:
http://pharmacy.unc.edu/faculty-research/faculty-directory/michaeljarstfer
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"Michael Jarstfer"
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Publications

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Moy SS, Teng BL, Nikolova VD, et al. (2018) Prosocial effects of an oxytocin metabolite, but not synthetic oxytocin receptor agonists, in a mouse model of autism. Neuropharmacology
Shirgahi Talari F, Bagherzadeh K, Golestanian S, et al. (2015) Potent Human Telomerase Inhibitors: Molecular Dynamic Simulations, Multiple Pharmacophore-Based Virtual Screening, and Biochemical Assays. Journal of Chemical Information and Modeling. 55: 2596-610
Shirgahi Talari F, Bagherzadeh K, Golestanian S, et al. (2015) Potent Human Telomerase Inhibitors: Molecular Dynamic Simulations, Multiple Pharmacophore-Based Virtual Screening, and Biochemical Assays Journal of Chemical Information and Modeling. 55: 2596-2610
Sekaran V, Soares J, Jarstfer MB. (2014) Telomere maintenance as a target for drug discovery. Journal of Medicinal Chemistry. 57: 521-38
Jarstfer MB, Shobair M, Wang Y. (2014) Solvent Kinetic Isotope Effects on 2'-Hydroxyl Acylation of RNA Biophysical Journal. 106: 2-5
Sassano MF, Schlesinger AP, Jarstfer MB. (2012) Identification of G-Quadruplex Inducers Usinga Simple, Inexpensiveand Rapid High Throughput Assay, and TheirInhibition of Human Telomerase. The Open Medicinal Chemistry Journal. 6: 20-8
Cole DI, Legassie JD, Bonifacio LN, et al. (2012) New models of Tetrahymena telomerase RNA from experimentally derived constraints and modeling. Journal of the American Chemical Society. 134: 20070-80
Shobair M, Cole D, Ding F, et al. (2012) Computational Modeling of Telomerase in Action Biophysical Journal. 102: 732a
Soares J, Keppler BR, Wang X, et al. (2011) ortho-Quinone tanshinones directly inhibit telomerase through an oxidative mechanism mediated by hydrogen peroxide. Bioorganic & Medicinal Chemistry Letters. 21: 7474-8
Soares J, Lowe MM, Jarstfer MB. (2011) The catalytic subunit of human telomerase is a unique caspase-6 and caspase-7 substrate. Biochemistry. 50: 9046-55
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