Harley I. Kornblum - Publications

Affiliations: 
University of California, Los Angeles, Los Angeles, CA 
Area:
Neural stem cells, development, brain tumors

129 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Muthukrishnan SD, Qi H, Wang D, Elahi L, Pham A, Alvarado AG, Li T, Gao F, Kawaguchi R, Lai A, Kornblum HI. Low- and high-grade glioma-associated vascular cells differentially regulate tumor growth. Molecular Cancer Research : McR. PMID 38441553 DOI: 10.1158/1541-7786.MCR-23-1069  0.321
2023 Ludwig K, Le Belle JE, Muthukrishnan SD, Sperry J, Condro M, Vlashi E, Pajonk F, Kornblum HI. NADPH oxidase promotes glioblastoma radiation resistance in a PTEN-dependent manner. Antioxidants & Redox Signaling. PMID 37470216 DOI: 10.1089/ars.2022.0086  0.77
2022 Muthukrishnan SD, Kawaguchi R, Nair P, Prasad R, Qin Y, Johnson M, Wang Q, VanderVeer-Harris N, Pham A, Alvarado AG, Condro MC, Gao F, Gau R, Castro MG, Lowenstein PR, ... ... Kornblum HI, et al. P300 promotes tumor recurrence by regulating radiation-induced conversion of glioma stem cells to vascular-like cells. Nature Communications. 13: 6202. PMID 36261421 DOI: 10.1038/s41467-022-33943-0  0.32
2022 Ghochani Y, Muthukrishnan SD, Sohrabi A, Kawaguchi R, Condro MC, Bastola S, Gao F, Qin Y, Mottahedeh J, Iruela-Arispe ML, Rao N, Laks DR, Liau LM, Mathern GW, Goldman SA, ... ... Kornblum HI, et al. A molecular interactome of the glioblastoma perivascular niche reveals integrin binding sialoprotein as a mediator of tumor cell migration. Cell Reports. 41: 111511. PMID 36261010 DOI: 10.1016/j.celrep.2022.111511  0.313
2022 Alvarado AG, Tessema K, Muthukrishnan SD, Sober M, Kawaguchi R, Laks DR, Bhaduri A, Swarup V, Nathanson DA, Geschwind DH, Goldman SA, Kornblum HI. Pathway-based approach reveals differential sensitivity to E2F1 inhibition in glioblastoma. Cancer Research Communications. 2: 1049-1060. PMID 36213002 DOI: 10.1158/2767-9764.crc-22-0003  0.373
2022 Watanabe M, Buth JE, Haney JR, Vishlaghi N, Turcios F, Elahi LS, Gu W, Pearson CA, Kurdian A, Baliaouri NV, Collier AJ, Miranda OA, Dunn N, Chen D, Sabri S, ... ... Kornblum HI, et al. TGFβ superfamily signaling regulates the state of human stem cell pluripotency and capacity to create well-structured telencephalic organoids. Stem Cell Reports. PMID 36179695 DOI: 10.1016/j.stemcr.2022.08.013  0.383
2020 Patel KS, Yao J, Raymond C, Yong W, Everson R, Liau LM, Nathanson D, Kornblum H, Wang C, Oughourlian T, Lai A, Nghiemphu PL, Pope WB, Cloughesy TF, Ellingson BM. Decorin expression is associated with predictive diffusion MR phenotypes of anti-VEGF efficacy in glioblastoma. Scientific Reports. 10: 14819. PMID 32908231 DOI: 10.1038/S41598-020-71799-W  0.314
2020 Sperry J, Condro MC, Guo L, Braas D, Vanderveer-Harris N, Kim KKO, Pope WB, Divakaruni AS, Lai A, Christofk H, Castro MG, Lowenstein PR, Le Belle JE, Kornblum HI. Glioblastoma Utilizes Fatty Acids and Ketone Bodies for Growth Allowing Progression during Ketogenic Diet Therapy. Iscience. 23: 101453. PMID 32861192 DOI: 10.1016/J.Isci.2020.101453  0.777
2020 Bhat K, Saki M, Vlashi E, Cheng F, Duhachek-Muggy S, Alli C, Yu G, Medina P, He L, Damoiseaux R, Pellegrini M, Zemke NR, Nghiemphu PL, Cloughesy TF, Liau LM, ... Kornblum HI, et al. The dopamine receptor antagonist trifluoperazine prevents phenotype conversion and improves survival in mouse models of glioblastoma. Proceedings of the National Academy of Sciences of the United States of America. PMID 32358191 DOI: 10.1073/Pnas.1920154117  0.316
2020 Bhat K, Medina P, He L, Zhang L, Saki M, Ioannidis A, Nguyen NT, Sodhi SS, Sung D, Magyar CE, Liau LM, Kornblum HI, Pajonk F. 1-[(4-Nitrophenyl)sulfonyl]-4-phenylpiperazine Treatment After Brain Irradiation Preserves Cognitive Function in Mice. Neuro-Oncology. PMID 32291451 DOI: 10.1093/Neuonc/Noaa095  0.389
2020 Yamashita D, Bernstock JD, Elsayed G, Sadahiro H, Mohyeldin A, Chagoya G, Ilyas A, Mooney J, Estevez-Ordonez D, Yamaguchi S, Flanary VL, Hackney JR, Bhat KP, Kornblum HI, Zamboni N, et al. Targeting glioma-initiating cells via the tyrosine metabolic pathway. Journal of Neurosurgery. 1-12. PMID 32059178 DOI: 10.3171/2019.11.Jns192028  0.374
2019 Peereboom DM, Alban TJ, Grabowski MM, Alvarado AG, Otvos B, Bayik D, Roversi G, McGraw M, Huang P, Mohammadi AM, Kornblum HI, Radivoyevitch T, Ahluwalia MS, Vogelbaum MA, Lathia JD. Metronomic capecitabine as an immune modulator in glioblastoma patients reduces myeloid-derived suppressor cells. Jci Insight. PMID 31600167 DOI: 10.1172/jci.insight.130748  0.359
2019 Bi J, Ichu TA, Zanca C, Yang H, Zhang W, Gu Y, Chowdhry S, Reed A, Ikegami S, Turner KM, Zhang W, Villa GR, Wu S, Quehenberger O, Yong WH, ... Kornblum HI, et al. Oncogene Amplification in Growth Factor Signaling Pathways Renders Cancers Dependent on Membrane Lipid Remodeling. Cell Metabolism. PMID 31303424 DOI: 10.1016/J.Cmet.2019.06.014  0.316
2019 Le Belle JE, Kornblum HI. Interactive Regulation of Neuronal Development by Hippocampal Stem Cell Niche Populations. Neuron. 101: 1-2. PMID 30605653 DOI: 10.1016/j.neuron.2018.12.017  0.451
2019 Alvarado A, Alban T, Nakano I, Lathia J, Goldman S, Kornblum H. CSIG-17. SIGNALING PATHWAY-BASED CLUSTERING OF MASS CYTOMETRY DATA UNCOVERS CELLS ASSOCIATED WITH CLINICAL PROGRESSION IN GLIOBLASTOMA Neuro-Oncology. 21: vi47-vi47. DOI: 10.1093/neuonc/noz175.187  0.407
2019 Alvarado A, Kawaguchi R, Coppola G, Goldman S, Kornblum H. CSIG-16. RECONCILING TUMOR HETEROGENEITY IN GLIOBLASTOMA USING A PATHWAY-BASED APPROACH Neuro-Oncology. 21: vi47-vi47. DOI: 10.1093/Neuonc/Noz175.186  0.353
2019 Elahi L, Garrett M, Guo L, Condro M, Kawaguchi R, Mehta S, Lai A, Pope W, Kornblum H. CBMT-31. HDAC INHIBITION DIMINISHES THE GROWTH OF ENDOGENOUS IDH MUTANT GLIOMAS Neuro-Oncology. 21: vi39-vi40. DOI: 10.1093/Neuonc/Noz175.153  0.386
2019 Bastola S, Ghochani Y, Pavlyukov MS, Ghosh S, Kurowsky M, Kornblum H, Nakano I. TMIC-63. ENDOCAN BRIDGING THE GAP: TUMOR ENDOTHELIAL CELL SECRETOME AND THE VASCULATURE-PROXIMAL TUMOR EDGE Neuro-Oncology. 21: vi261-vi262. DOI: 10.1093/neuonc/noz175.1097  0.474
2019 Deepthi Muthukrishnan S, Wang Q, Qin Y, Kawaguchi R, Johnson M, Prasad R, Condro M, Kornblum H. TMIC-45. RADIATION THERAPY-INDUCED EPIGENETIC REWIRING PROMOTES GLIOMA PHENOTYPIC PLASTICITY Neuro-Oncology. 21: vi257-vi257. DOI: 10.1093/Neuonc/Noz175.1079  0.454
2018 Chen AS, Wardwell-Ozgo J, Shah NN, Wright D, Appin CL, Vigneswaran K, Brat DJ, Kornblum HI, Read RD. Drak/STK17A drives neoplastic glial proliferation through modulation of MRLC signaling. Cancer Research. PMID 30530503 DOI: 10.1158/0008-5472.Can-18-0482  0.366
2018 Alban TJ, Alvarado AG, Sorensen MD, Bayik D, Volovetz J, Serbinowski E, Mulkearns-Hubert EE, Sinyuk M, Hale JS, Onzi GR, McGraw M, Huang P, Grabowski MM, Wathen CA, Ahluwalia MS, ... ... Kornblum HI, et al. Global immune fingerprinting in glioblastoma patient peripheral blood reveals immune-suppression signatures associated with prognosis. Jci Insight. 3. PMID 30385717 DOI: 10.1172/jci.insight.122264  0.302
2018 Garrett M, Sperry J, Braas D, Yan W, Le TM, Mottahedeh J, Ludwig K, Eskin A, Qin Y, Levy R, Breunig JJ, Pajonk F, Graeber TG, Radu CG, Christofk H, ... ... Kornblum HI, et al. Metabolic characterization of isocitrate dehydrogenase (IDH) mutant and IDH wildtype gliomaspheres uncovers cell type-specific vulnerabilities. Cancer & Metabolism. 6: 4. PMID 29692895 DOI: 10.1186/S40170-018-0177-4  0.304
2018 Muthukrishnan SD, Alvarado AG, Kornblum HI. Building Bonds: Cancer Stem Cells Depend on Their Progeny to Drive Tumor Progression. Cell Stem Cell. 22: 473-474. PMID 29625062 DOI: 10.1016/j.stem.2018.03.008  0.494
2018 Alvarado A, Kawaguchi R, Coppola G, Goldman S, Kornblum H. CSIG-22. RECONCILING TUMOR HETEROGENEITY IN GLIOBLASTOMA USING A PATHWAY-BASED APPROACH Neuro-Oncology. 20: vi47-vi47. DOI: 10.1093/Neuonc/Noy148.188  0.306
2018 Deepthi Muthukrishnan S, Condro M, Tessema K, Johnson M, Kornblum H. TMIC-47. GLIOMA STEM CELL-VASCULAR INTERFACE IN GLIOBLASTOMA PROGRESSION Neuro-Oncology. 20: vi266-vi266. DOI: 10.1093/neuonc/noy148.1106  0.433
2017 Le TM, Poddar S, Capri JR, Abt ER, Kim W, Wei L, Uong NT, Cheng CM, Braas D, Nikanjam M, Rix P, Merkurjev D, Zaretsky J, Kornblum HI, Ribas A, et al. ATR inhibition facilitates targeting of leukemia dependence on convergent nucleotide biosynthetic pathways. Nature Communications. 8: 241. PMID 28808226 DOI: 10.1038/S41467-017-00221-3  0.315
2017 Wang J, Cheng P, Pavlyukov MS, Yu H, Zhang Z, Kim SH, Minata M, Mohyeldin A, Xie W, Chen D, Goidts V, Frett B, Hu W, Li H, Shin YJ, ... ... Kornblum HI, et al. Targeting NEK2 attenuates glioblastoma growth and radioresistance by destabilizing histone methyltransferase EZH2. The Journal of Clinical Investigation. PMID 28737508 DOI: 10.1172/Jci89092  0.41
2017 Ludwig K, Kornblum HI. Molecular markers in glioma. Journal of Neuro-Oncology. PMID 28233083 DOI: 10.1007/s11060-017-2379-y  0.436
2017 Bastola S, Pavlyukov MS, Yamaguchi S, Wang J, Komarova S, kornblum HI, Nakano I. Abstract 4332: Interactome between vascular endothelial cells and Proneural glioma stem cells protects seeds for GBM recurrence from radiation therapy Cancer Research. 77: 4332-4332. DOI: 10.1158/1538-7445.Am2017-4332  0.364
2017 Bastola S, Pavlyukov M, Ghochani Y, Yu H, Zhang S, Yamaguchi S, Minata M, Coppola G, Kang K, Alsheikh HA, Kawaguchi R, Wang J, Komarova S, Varambally S, Chandrashekar DS, ... Kornblum H, et al. TMIC-36. CROSSTALK OF GLIOMA STEM CELLS WITH VASCULAR ENDOTHELIAL CELLS PERSISTS THEIR PRONEURAL PHENOTYPE AND THERAPY RESISTANCE VIA ENDOCAN-CD11A INTERACTION Neuro-Oncology. 19: vi251-vi251. DOI: 10.1093/Neuonc/Nox168.1024  0.387
2016 Laks DR, Ta L, Crisman TJ, Gao F, Coppola G, Radu CG, Nathanson DA, Kornblum HI. Inhibition of Nucleotide Synthesis Targets Brain Tumor Stem Cells in a Subset of Glioblastoma. Molecular Cancer Therapeutics. PMID 27196770 DOI: 10.1158/1535-7163.Mct-15-0982  0.411
2016 Wardwell-Ozgo J, Mosley C, Kornblum H, Read R. Abstract A02: A kinome-wide RNAi screen in Drosophila glia and human GBM models reveals Stk17A drives neoplastic glial proliferation and migration Molecular Cancer Research. 14. DOI: 10.1158/1557-3125.Devbiolca15-A02  0.41
2015 Shoemaker LD, Kornblum HI. Neural stem cell diversity and proteomics. Molecular & Cellular Proteomics : McP. PMID 26494823 DOI: 10.1074/Mcp.O115.052704  0.815
2015 Ganguly R, Mohyeldin A, Thiel J, Kornblum HI, Beullens M, Nakano I. MELK-a conserved kinase: functions, signaling, cancer, and controversy. Clinical and Translational Medicine. 4: 11. PMID 25852826 DOI: 10.1186/S40169-014-0045-Y  0.437
2015 Ludwig K, Kornblum H. Abstract B31: NOX2 generated reactive oxygen species promotes glioblastoma growth through inhibition of PTEN Brain. 75. DOI: 10.1158/1538-7445.Brain15-B31  0.423
2015 Ludwig K, Kornblum H. TMIC-16NOX GENERATED REACTIVE OXYGEN SPECIES PROMOTES GLIOBLASTOMA GROWTH AND SURVIVAL THROUGH INACTIVATION OF PTEN Neuro-Oncology. 17: v217.8-v217. DOI: 10.1093/neuonc/nov236.16  0.38
2015 Ghochani Y, Kawaguchi R, Coppola G, Kornblum H. TMIC-11NOVEL ANGIOCRINE CANDIDATES IN GLIOBLASTOMA PROGENITOR CELL PERIVASCULAR NICHE INTERACTIONS Neuro-Oncology. 17: v216.7-v216. DOI: 10.1093/Neuonc/Nov236.11  0.449
2014 Le Belle JE, Sperry J, Ngo A, Ghochani Y, Laks DR, López-Aranda M, Silva AJ, Kornblum HI. Maternal inflammation contributes to brain overgrowth and autism-associated behaviors through altered redox signaling in stem and progenitor cells. Stem Cell Reports. 3: 725-34. PMID 25418720 DOI: 10.1016/j.stemcr.2014.09.004  0.815
2014 Fabritius AL, Vesa J, Minye HM, Nakano I, Kornblum H, Peltonen L. Neuronal ceroid lipofuscinosis genes, CLN2, CLN3 and CLN5 are spatially and temporally co-expressed in a developing mouse brain. Experimental and Molecular Pathology. 97: 484-91. PMID 25303899 DOI: 10.1016/j.yexmp.2014.10.003  0.435
2014 Thomsen GM, Le Belle JE, Harnisch JA, Mc Donald WS, Hovda DA, Sofroniew MV, Kornblum HI, Harris NG. Traumatic brain injury reveals novel cell lineage relationships within the subventricular zone. Stem Cell Research. 13: 48-60. PMID 24835668 DOI: 10.1016/J.Scr.2014.04.013  0.818
2014 Ganguly R, Hong CS, Smith LG, Kornblum HI, Nakano I. Maternal embryonic leucine zipper kinase: key kinase for stem cell phenotype in glioma and other cancers. Molecular Cancer Therapeutics. 13: 1393-8. PMID 24795222 DOI: 10.1158/1535-7163.MCT-13-0764  0.369
2014 Minata M, Gu C, Joshi K, Nakano-Okuno M, Hong C, Nguyen CH, Kornblum HI, Molla A, Nakano I. Multi-kinase inhibitor C1 triggers mitotic catastrophe of glioma stem cells mainly through MELK kinase inhibition. Plos One. 9: e92546. PMID 24739874 DOI: 10.1371/journal.pone.0092546  0.408
2014 Panosyan EH, Wang Y, Xia P, Lee WN, Pak Y, Laks DR, Lin HJ, Moore TB, Cloughesy TF, Kornblum HI, Lasky JL. Asparagine depletion potentiates the cytotoxic effect of chemotherapy against brain tumors. Molecular Cancer Research : McR. 12: 694-702. PMID 24505127 DOI: 10.1158/1541-7786.MCR-13-0576  0.451
2014 Nathanson DA, Gini B, Mottahedeh J, Visnyei K, Koga T, Gomez G, Eskin A, Hwang K, Wang J, Masui K, Paucar A, Yang H, Ohashi M, Zhu S, Wykosky J, ... ... Kornblum HI, et al. Targeted therapy resistance mediated by dynamic regulation of extrachromosomal mutant EGFR DNA. Science (New York, N.Y.). 343: 72-6. PMID 24310612 DOI: 10.1126/Science.1241328  0.306
2013 Akhavan D, Pourzia AL, Nourian AA, Williams KJ, Nathanson D, Babic I, Villa GR, Tanaka K, Nael A, Yang H, Dang J, Vinters HV, Yong WH, Flagg M, Tamanoi F, ... ... Kornblum HI, et al. De-repression of PDGFRβ transcription promotes acquired resistance to EGFR tyrosine kinase inhibitors in glioblastoma patients. Cancer Discovery. 3: 534-47. PMID 23533263 DOI: 10.1158/2159-8290.Cd-12-0502  0.356
2013 Joshi K, Banasavadi-Siddegowda Y, Mo X, Kim SH, Mao P, Kig C, Nardini D, Sobol RW, Chow LM, Kornblum HI, Waclaw R, Beullens M, Nakano I. MELK-dependent FOXM1 phosphorylation is essential for proliferation of glioma stem cells. Stem Cells (Dayton, Ohio). 31: 1051-63. PMID 23404835 DOI: 10.1002/Stem.1358  0.514
2012 Phillips T, Martin L, Kornblum H, Xing L. SU-E-T-03: Justification and Feasibility of Neural Stem Cell Sparing in Whole Brain Irradiation Using VMAT. Medical Physics. 39: 3702-3703. PMID 28519063 DOI: 10.1118/1.4735057  0.373
2012 Chou AP, Chowdhury R, Li S, Chen W, Kim AJ, Piccioni DE, Selfridge JM, Mody RR, Chang S, Lalezari S, Lin J, Sanchez DE, Wilson RW, Garrett MC, Harry B, ... ... Kornblum HI, et al. Identification of retinol binding protein 1 promoter hypermethylation in isocitrate dehydrogenase 1 and 2 mutant gliomas. Journal of the National Cancer Institute. 104: 1458-69. PMID 22945948 DOI: 10.1093/Jnci/Djs357  0.328
2012 Pope WB, Prins RM, Albert Thomas M, Nagarajan R, Yen KE, Bittinger MA, Salamon N, Chou AP, Yong WH, Soto H, Wilson N, Driggers E, Jang HG, Su SM, Schenkein DP, ... ... Kornblum HI, et al. Non-invasive detection of 2-hydroxyglutarate and other metabolites in IDH1 mutant glioma patients using magnetic resonance spectroscopy. Journal of Neuro-Oncology. 107: 197-205. PMID 22015945 DOI: 10.1007/S11060-011-0737-8  0.318
2012 Laks DR, Phillips T, Paucar AA, Orozco N, Visnyei K, Mischel PS, Coppola G, Trinidad JC, Burlingame AL, Bradshaw RA, Kornblum HI. Abstract 5607: TLE4 is a key modulator of resistance to mTOR pathway specific inhibition in glioblastoma Cancer Research. 72: 5607-5607. DOI: 10.1158/1538-7445.Am2012-5607  0.318
2011 Liu Y, Ye F, Yamada K, Tso JL, Zhang Y, Nguyen DH, Dong Q, Soto H, Choe J, Dembo A, Wheeler H, Eskin A, Schmid I, Yong WH, Mischel PS, ... ... Kornblum HI, et al. Autocrine endothelin-3/endothelin receptor B signaling maintains cellular and molecular properties of glioblastoma stem cells. Molecular Cancer Research : McR. 9: 1668-85. PMID 22013079 DOI: 10.1158/1541-7786.Mcr-10-0563  0.523
2011 Jijiwa M, Demir H, Gupta S, Leung C, Joshi K, Orozco N, Huang T, Yildiz VO, Shibahara I, de Jesus JA, Yong WH, Mischel PS, Fernandez S, Kornblum HI, Nakano I. CD44v6 regulates growth of brain tumor stem cells partially through the AKT-mediated pathway. Plos One. 6: e24217. PMID 21915300 DOI: 10.1371/Journal.Pone.0024217  0.454
2011 Visnyei K, Onodera H, Damoiseaux R, Saigusa K, Petrosyan S, De Vries D, Ferrari D, Saxe J, Panosyan EH, Masterman-Smith M, Mottahedeh J, Bradley KA, Huang J, Sabatti C, Nakano I, ... Kornblum HI, et al. A molecular screening approach to identify and characterize inhibitors of glioblastoma stem cells. Molecular Cancer Therapeutics. 10: 1818-28. PMID 21859839 DOI: 10.1158/1535-7163.Mct-11-0268  0.807
2011 Nakano I, Joshi K, Visnyei K, Hu B, Watanabe M, Lam D, Wexler E, Saigusa K, Nakamura Y, Laks DR, Mischel PS, Viapiano M, Kornblum HI. Siomycin A targets brain tumor stem cells partially through a MELK-mediated pathway. Neuro-Oncology. 13: 622-34. PMID 21558073 DOI: 10.1093/Neuonc/Nor023  0.517
2011 Le Belle JE, Orozco NM, Paucar AA, Saxe JP, Mottahedeh J, Pyle AD, Wu H, Kornblum HI. Proliferative neural stem cells have high endogenous ROS levels that regulate self-renewal and neurogenesis in a PI3K/Akt-dependant manner. Cell Stem Cell. 8: 59-71. PMID 21211782 DOI: 10.1016/J.Stem.2010.11.028  0.818
2011 Jijiwa M, Gupta S, Demir H, Leung C, Chaudhury AR, Kornblum HI, Nakano I. Abstract LB-103: Signaling via CD44v6 is associated with the growth of CD44-expressing glioma stem-like cells Cancer Research. 71. DOI: 10.1158/1538-7445.Am2011-Lb-103  0.345
2010 Neveu P, Kye MJ, Qi S, Buchholz DE, Clegg DO, Sahin M, Park IH, Kim KS, Daley GQ, Kornblum HI, Shraiman BI, Kosik KS. MicroRNA profiling reveals two distinct p53-related human pluripotent stem cell states. Cell Stem Cell. 7: 671-81. PMID 21112562 DOI: 10.1016/J.Stem.2010.11.012  0.59
2010 Laks DR, Visnyei K, Kornblum HI. Brain tumor stem cells as therapeutic targets in models of glioma. Yonsei Medical Journal. 51: 633-40. PMID 20635435 DOI: 10.3349/ymj.2010.51.5.633  0.498
2010 Sun J, Masterman-Smith MD, Graham NA, Jiao J, Mottahedeh J, Laks DR, Ohashi M, DeJesus J, Kamei K, Lee KB, Wang H, Yu ZT, Lu YT, Hou S, Li K, ... ... Kornblum HI, et al. A microfluidic platform for systems pathology: multiparameter single-cell signaling measurements of clinical brain tumor specimens. Cancer Research. 70: 6128-38. PMID 20631065 DOI: 10.1158/0008-5472.Can-10-0076  0.789
2010 Panosyan EH, Laks DR, Masterman-Smith M, Mottahedeh J, Yong WH, Cloughesy TF, Lazareff JA, Mischel PS, Moore TB, Kornblum HI. Clinical outcome in pediatric glial and embryonal brain tumors correlates with in vitro multi-passageable neurosphere formation. Pediatric Blood & Cancer. 55: 644-51. PMID 20589659 DOI: 10.1002/Pbc.22627  0.792
2010 Kornblum HI. A multipronged approach to the identification and study of an important oncogene in GBM. Cancer Cell. 17: 417-8. PMID 20478522 DOI: 10.1016/j.ccr.2010.04.019  0.34
2010 Zhong J, Chan A, Morad L, Kornblum HI, Fan G, Carmichael ST. Hydrogel matrix to support stem cell survival after brain transplantation in stroke. Neurorehabilitation and Neural Repair. 24: 636-44. PMID 20424193 DOI: 10.1177/1545968310361958  0.343
2010 Shoemaker LD, Orozco NM, Geschwind DH, Whitelegge JP, Faull KF, Kornblum HI. Identification of differentially expressed proteins in murine embryonic and postnatal cortical neural progenitors. Plos One. 5: e9121. PMID 20161753 DOI: 10.1371/Journal.Pone.0009121  0.797
2010 Joseph I, Matsui W, LaPorta CAM, Tabori U, Kornblum H, Herbert B, Harley C, Tressler RJ. Abstract 4291: Imetelstat, a telomerase inhibitor in phase I trials in solid tumor and hematological malignancies, has broad activity against multiple types of cancer stem cells Cancer Research. 70: 4291-4291. DOI: 10.1158/1538-7445.Am10-4291  0.419
2010 Okemoto-Nakamura Y, Kornblum HI, Nakano I. Abstract 4236: Characterization of maternal embryonic leucine zipper kinase in cancer stem/progenitor cells Cancer Research. 70: 4236-4236. DOI: 10.1158/1538-7445.Am10-4236  0.55
2009 Nakano I, Kornblum HI. Methods for analysis of brain tumor stem cell and neural stem cell self-renewal. Methods in Molecular Biology (Clifton, N.J.). 568: 37-56. PMID 19582420 DOI: 10.1007/978-1-59745-280-9_4  0.554
2009 Wexler EM, Paucer A, Kornblum HI, Palmer TD, Plamer TD, Geschwind DH. Endogenous Wnt signaling maintains neural progenitor cell potency. Stem Cells (Dayton, Ohio). 27: 1130-41. PMID 19418460 DOI: 10.1002/stem.36  0.432
2009 Laks DR, Masterman-Smith M, Visnyei K, Angenieux B, Orozco NM, Foran I, Yong WH, Vinters HV, Liau LM, Lazareff JA, Mischel PS, Cloughesy TF, Horvath S, Kornblum HI. Neurosphere formation is an independent predictor of clinical outcome in malignant glioma. Stem Cells (Dayton, Ohio). 27: 980-7. PMID 19353526 DOI: 10.1002/Stem.15  0.79
2009 Karumbayaram S, Novitch BG, Patterson M, Umbach JA, Richter L, Lindgren A, Conway AE, Clark AT, Goldman SA, Plath K, Wiedau-Pazos M, Kornblum HI, Lowry WE. Directed differentiation of human-induced pluripotent stem cells generates active motor neurons. Stem Cells (Dayton, Ohio). 27: 806-11. PMID 19350680 DOI: 10.1002/Stem.31  0.37
2009 Karumbayaram S, Kelly TK, Paucar AA, Roe AJ, Umbach JA, Charles A, Goldman SA, Kornblum HI, Wiedau-Pazos M. Human embryonic stem cell-derived motor neurons expressing SOD1 mutants exhibit typical signs of motor neuron degeneration linked to ALS. Disease Models & Mechanisms. 2: 189-95. PMID 19259395 DOI: 10.1242/Dmm.002113  0.744
2009 Gregorian C, Nakashima J, Le Belle J, Ohab J, Kim R, Liu A, Smith KB, Groszer M, Garcia AD, Sofroniew MV, Carmichael ST, Kornblum HI, Liu X, Wu H. Pten deletion in adult neural stem/progenitor cells enhances constitutive neurogenesis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 1874-86. PMID 19211894 DOI: 10.1523/Jneurosci.3095-08.2009  0.807
2009 Kelly TK, Karsten SL, Geschwind DH, Kornblum HI. Cell lineage and regional identity of cultured spinal cord neural stem cells and comparison to brain-derived neural stem cells. Plos One. 4: e4213. PMID 19148290 DOI: 10.1371/Journal.Pone.0004213  0.756
2009 Wexler EM, Andres P, Kornblum HI, Palmer TD, Geschwind DH. Endogenous Wnt signaling maintains neural progenitor cell potency (Stem Cells (2009) 27, (1130)) Stem Cells. 27: 2636. DOI: 10.1002/stem.239  0.377
2008 Ratan RR, Siddiq A, Aminova L, Langley B, McConoughey S, Karpisheva K, Lee HH, Carmichael T, Kornblum H, Coppola G, Geschwind DH, Hoke A, Smirnova N, Rink C, Roy S, et al. Small molecule activation of adaptive gene expression: tilorone or its analogs are novel potent activators of hypoxia inducible factor-1 that provide prophylaxis against stroke and spinal cord injury. Annals of the New York Academy of Sciences. 1147: 383-94. PMID 19076458 DOI: 10.1196/Annals.1427.033  0.314
2008 Erickson RI, Paucar AA, Jackson RL, Visnyei K, Kornblum H. Roles of insulin and transferrin in neural progenitor survival and proliferation. Journal of Neuroscience Research. 86: 1884-94. PMID 18293414 DOI: 10.1002/Jnr.21631  0.755
2008 Nakano I, Saigusa K, Kornblum HI. BMPing off glioma stem cells. Cancer Cell. 13: 3-4. PMID 18167333 DOI: 10.1016/j.ccr.2007.12.018  0.505
2008 Lelievre V, Seksenyan A, Nobuta H, Yong WH, Chhith S, Niewiadomski P, Cohen JR, Dong H, Flores A, Liau LM, Kornblum HI, Scott MP, Waschek JA. Disruption of the PACAP gene promotes medulloblastoma in ptc1 mutant mice. Developmental Biology. 313: 359-70. PMID 18036580 DOI: 10.1016/J.Ydbio.2007.10.031  0.4
2008 Nakano I, Masterman-Smith M, Saigusa K, Paucar AA, Horvath S, Shoemaker L, Watanabe M, Negro A, Bajpai R, Howes A, Lelievre V, Waschek JA, Lazareff JA, Freije WA, Liau LM, ... ... Kornblum HI, et al. Maternal embryonic leucine zipper kinase is a key regulator of the proliferation of malignant brain tumors, including brain tumor stem cells. Journal of Neuroscience Research. 86: 48-60. PMID 17722061 DOI: 10.1002/Jnr.21471  0.824
2007 Saxe JP, Wu H, Kelly TK, Phelps ME, Sun YE, Kornblum HI, Huang J. A phenotypic small-molecule screen identifies an orphan ligand-receptor pair that regulates neural stem cell differentiation. Chemistry & Biology. 14: 1019-30. PMID 17884634 DOI: 10.1016/J.Chembiol.2007.07.016  0.774
2007 Liu T, Papagiannakopoulos T, Puskar K, Qi S, Santiago F, Clay W, Lao K, Lee Y, Nelson SF, Kornblum HI, Doyle F, Petzold L, Shraiman B, Kosik KS. Detection of a microRNA signal in an in vivo expression set of mRNAs. Plos One. 2: e804. PMID 17726534 DOI: 10.1371/Journal.Pone.0000804  0.49
2007 Nakano I, Dougherty JD, Kim K, Klement I, Geschwind DH, Kornblum HI. Phosphoserine phosphatase is expressed in the neural stem cell niche and regulates neural stem and progenitor cell proliferation. Stem Cells (Dayton, Ohio). 25: 1975-84. PMID 17495110 DOI: 10.1634/Stemcells.2007-0046  0.534
2007 Kornblum HI. Introduction to neural stem cells. Stroke; a Journal of Cerebral Circulation. 38: 810-6. PMID 17261745 DOI: 10.1161/01.STR.0000255757.12198.0f  0.48
2007 Cheng JC, Horwitz EM, Karsten SL, Shoemaker L, Kornblum HI, Malik P, Sakamoto KM. Report on the workshop "New Technologies in Stem Cell Research," Society for Pediatric Research, San Francisco, California, April 29, 2006. Stem Cells (Dayton, Ohio). 25: 1070-88. PMID 17255523 DOI: 10.1634/Stemcells.2006-0397  0.762
2006 Horvath S, Zhang B, Carlson M, Lu KV, Zhu S, Felciano RM, Laurance MF, Zhao W, Qi S, Chen Z, Lee Y, Scheck AC, Liau LM, Wu H, Geschwind DH, ... ... Kornblum HI, et al. Analysis of oncogenic signaling networks in glioblastoma identifies ASPM as a molecular target. Proceedings of the National Academy of Sciences of the United States of America. 103: 17402-7. PMID 17090670 DOI: 10.1073/pnas.0608396103  0.6
2006 Nakano I, Kornblum HI. Brain tumor stem cells. Pediatric Research. 59: 54R-8R. PMID 16549549 DOI: 10.1203/01.pdr.0000203568.63482.f9  0.54
2006 Groszer M, Erickson R, Scripture-Adams DD, Dougherty JD, Le Belle J, Zack JA, Geschwind DH, Liu X, Kornblum HI, Wu H. PTEN negatively regulates neural stem cell self-renewal by modulating G0-G1 cell cycle entry. Proceedings of the National Academy of Sciences of the United States of America. 103: 111-6. PMID 16373498 DOI: 10.1073/Pnas.0509939103  0.828
2006 Visnyei K, Tatsukawa KJ, Erickson RI, Simonian S, Oknaian N, Carmichael ST, Kornblum HI. Neural progenitor implantation restores metabolic deficits in the brain following striatal quinolinic acid lesion. Experimental Neurology. 197: 465-74. PMID 16310773 DOI: 10.1016/J.Expneurol.2005.10.023  0.748
2006 Imura T, Nakano I, Kornblum HI, Sofroniew MV. Phenotypic and functional heterogeneity of GFAP-expressing cells in vitro: differential expression of LeX/CD15 by GFAP-expressing multipotent neural stem cells and non-neurogenic astrocytes. Glia. 53: 277-93. PMID 16267834 DOI: 10.1002/glia.20281  0.441
2005 Dougherty JD, Garcia AD, Nakano I, Livingstone M, Norris B, Polakiewicz R, Wexler EM, Sofroniew MV, Kornblum HI, Geschwind DH. PBK/TOPK, a proliferating neural progenitor-specific mitogen-activated protein kinase kinase. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 10773-85. PMID 16291951 DOI: 10.1523/Jneurosci.3207-05.2005  0.492
2005 Nakano I, Paucar AA, Bajpai R, Dougherty JD, Zewail A, Kelly TK, Kim KJ, Ou J, Groszer M, Imura T, Freije WA, Nelson SF, Sofroniew MV, Wu H, Liu X, ... ... Kornblum HI, et al. Maternal embryonic leucine zipper kinase (MELK) regulates multipotent neural progenitor proliferation. The Journal of Cell Biology. 170: 413-27. PMID 16061694 DOI: 10.1083/Jcb.200412115  0.779
2005 Fox IJ, Kornblum HI. Developmental profile of ErbB receptors in murine central nervous system: implications for functional interactions. Journal of Neuroscience Research. 79: 584-97. PMID 15682390 DOI: 10.1002/Jnr.20381  0.357
2004 Nakano I, Hemmati HD, Kornblum HI. [Cancer stem cells in pediatric brain tumors]. No Shinkei Geka. Neurological Surgery. 32: 827-34. PMID 15478649  0.443
2004 Fox IJ, Paucar AA, Nakano I, Mottahedeh J, Dougherty JD, Kornblum HI. Developmental expression of glial fibrillary acidic protein mRNA in mouse forebrain germinal zones--implications for stem cell biology. Brain Research. Developmental Brain Research. 153: 121-5. PMID 15464225 DOI: 10.1016/J.Devbrainres.2004.07.011  0.508
2004 Tiwari-Woodruff SK, Kaplan R, Kornblum HI, Bronstein JM. Developmental expression of OAP-1/Tspan-3, a member of the tetraspanin superfamily. Journal of Neuroscience Research. 77: 166-73. PMID 15211584 DOI: 10.1002/Jnr.20141  0.391
2004 Irvin DK, Nakano I, Paucar A, Kornblum HI. Patterns of Jagged1, Jagged2, Delta-like 1 and Delta-like 3 expression during late embryonic and postnatal brain development suggest multiple functional roles in progenitors and differentiated cells. Journal of Neuroscience Research. 75: 330-43. PMID 14743446 DOI: 10.1002/Jnr.10843  0.757
2004 Hemmati HD, Nakano I, Masterman-Smith M, Bababeygy SR, Rafii B, Minera M, Lowry AK, Lazareff JA, Kornblum HI, Bronner-Fraser M. 531 CHARACTERIZATION OF CANCEROUS STEM CELLS IN HUMAN PEDIATRIC BRAIN TUMORS. Journal of Investigative Medicine. 52: S172.2-S172. DOI: 10.1136/Jim-52-Suppl1-531  0.814
2004 Hemmati HD, Nakano I, Masterman-Smith M, Bababeygy SR, Rafii B, Minera M, Lowry AK, Lazareff JA, Kornblum HI, Bronner-Fraser M. CHARACTERIZATION OF CANCEROUS STEM CELLS IN HUMAN PEDIATRIC BRAIN TUMORS. Journal of Investigative Medicine. 52: S172. DOI: 10.1097/00042871-200401001-00531  0.814
2003 Easterday MC, Dougherty JD, Jackson RL, Ou J, Nakano I, Paucar AA, Roobini B, Dianati M, Irvin DK, Weissman IL, Terskikh AV, Geschwind DH, Kornblum HI. Neural progenitor genes. Germinal zone expression and analysis of genetic overlap in stem cell populations. Developmental Biology. 264: 309-22. PMID 14651920 DOI: 10.1016/J.Ydbio.2003.09.003  0.811
2003 Hemmati HD, Nakano I, Lazareff JA, Masterman-Smith M, Geschwind DH, Bronner-Fraser M, Kornblum HI. Cancerous stem cells can arise from pediatric brain tumors. Proceedings of the National Academy of Sciences of the United States of America. 100: 15178-83. PMID 14645703 DOI: 10.1073/Pnas.2036535100  0.834
2003 Irvin DK, Dhaka A, Hicks C, Weinmaster G, Kornblum HI. Extrinsic and intrinsic factors governing cell fate in cortical progenitor cultures. Developmental Neuroscience. 25: 162-72. PMID 12966214 DOI: 10.1159/000072265  0.794
2003 Karsten SL, Kudo LC, Jackson R, Sabatti C, Kornblum HI, Geschwind DH. Global analysis of gene expression in neural progenitors reveals specific cell-cycle, signaling, and metabolic networks. Developmental Biology. 261: 165-82. PMID 12941627 DOI: 10.1016/S0012-1606(03)00274-4  0.497
2003 Fu L, Abu-Khalil A, Morrison RS, Geschwind DH, Kornblum HI. Expression patterns of epidermal growth factor receptor and fibroblast growth factor receptor 1 mRNA in fetal human brain. The Journal of Comparative Neurology. 462: 265-73. PMID 12794748 DOI: 10.1002/Cne.10727  0.419
2003 Imura T, Kornblum HI, Sofroniew MV. The predominant neural stem cell isolated from postnatal and adult forebrain but not early embryonic forebrain expresses GFAP. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 2824-32. PMID 12684469 DOI: 10.1523/Jneurosci.23-07-02824.2003  0.456
2003 Dhaka A, Costa RM, Hu H, Irvin DK, Patel A, Kornblum HI, Silva AJ, O'Dell TJ, Colicelli J. The RAS effector RIN1 modulates the formation of aversive memories. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 748-57. PMID 12574403 DOI: 10.1523/Jneurosci.23-03-00748.2003  0.714
2001 Kornblum HI, Geschwind DH. Molecular markers in CNS stem cell research: hitting a moving target. Nature Reviews. Neuroscience. 2: 843-6. PMID 11715062 DOI: 10.1038/35097597  0.507
2001 Groszer M, Erickson R, Scripture-Adams DD, Lesche R, Trumpp A, Zack JA, Kornblum HI, Liu X, Wu H. Negative regulation of neural stem/progenitor cell proliferation by the Pten tumor suppressor gene in vivo. Science (New York, N.Y.). 294: 2186-9. PMID 11691952 DOI: 10.1126/Science.1065518  0.812
2001 Irvin DK, Zurcher SD, Nguyen T, Weinmaster G, Kornblum HI. Expression patterns of Notch1, Notch2, and Notch3 suggest multiple functional roles for the Notch-DSL signaling system during brain development. The Journal of Comparative Neurology. 436: 167-81. PMID 11438922 DOI: 10.1002/Cne.1059  0.772
2001 Terskikh AV, Easterday MC, Li L, Hood L, Kornblum HI, Geschwind DH, Weissman IL. From hematopoiesis to neuropoiesis: evidence of overlapping genetic programs. Proceedings of the National Academy of Sciences of the United States of America. 98: 7934-9. PMID 11438738 DOI: 10.1046/J.1471-4159.81.S1.105.X  0.83
2001 Tiwari-Woodruff SK, Buznikov AG, Vu TQ, Micevych PE, Chen K, Kornblum HI, Bronstein JM. OSP/claudin-11 forms a complex with a novel member of the tetraspanin super family and beta1 integrin and regulates proliferation and migration of oligodendrocytes. The Journal of Cell Biology. 153: 295-305. PMID 11309411 DOI: 10.1083/Jcb.153.2.295  0.312
2001 Geschwind DH, Ou J, Easterday MC, Dougherty JD, Jackson RL, Chen Z, Antoine H, Terskikh A, Weissman IL, Nelson SF, Kornblum HI. A genetic analysis of neural progenitor differentiation. Neuron. 29: 325-39. PMID 11239426 DOI: 10.1016/S0896-6273(01)00209-4  0.81
2001 Kinoshita Y, Jarell AD, Flaman JM, Foltz G, Schuster J, Sopher BL, Irvin DK, Kanning K, Kornblum HI, Nelson PS, Hieter P, Morrison RS. Pescadillo, a novel cell cycle regulatory protein abnormally expressed in malignant cells. The Journal of Biological Chemistry. 276: 6656-65. PMID 11071894 DOI: 10.1074/Jbc.M008536200  0.784
2000 Kornblum HI, Araujo DM, Annala AJ, Tatsukawa KJ, Phelps ME, Cherry SR. In vivo imaging of neuronal activation and plasticity in the rat brain by high resolution positron emission tomography (microPET). Nature Biotechnology. 18: 655-60. PMID 10835605 DOI: 10.1038/76509  0.304
2000 Bronstein JM, Chen K, Tiwari-Woodruff S, Kornblum HI. Developmental expression of OSP/claudin-11. Journal of Neuroscience Research. 60: 284-90. PMID 10797530 DOI: 10.1002/(Sici)1097-4547(20000501)60:3<284::Aid-Jnr2>3.0.Co;2-T  0.391
2000 Liau LM, Lallone RL, Seitz RS, Buznikov A, Gregg JP, Kornblum HI, Nelson SF, Bronstein JM. Identification of a human glioma-associated growth factor gene, granulin, using differential immuno-absorption. Cancer Research. 60: 1353-60. PMID 10728698  0.377
2000 Kornblum HI, Yanni DS, Easterday MC, Seroogy KB. Expression of the EGF receptor family members ErbB2, ErbB3, and ErbB4 in germinal zones of the developing brain and in neurosphere cultures containing CNS stem cells. Developmental Neuroscience. 22: 16-24. PMID 10657694 DOI: 10.1159/000017423  0.816
2000 Terskikh A, Easterday M, Li L, Hood L, Kornblum H, Geschwind D, Weissman I. Genes that expressed specifically and in common in adult mouse hematopoietic stem cells and neural stem/ progenitor cells Blood. 96: 278a-279a.  0.411
1998 Kornblum HI, Hussain R, Wiesen J, Miettinen P, Zurcher SD, Chow K, Derynck R, Werb Z. Abnormal astrocyte development and neuronal death in mice lacking the epidermal growth factor receptor. Journal of Neuroscience Research. 53: 697-717. PMID 9753198 DOI: 10.1002/(Sici)1097-4547(19980915)53:6<697::Aid-Jnr8>3.0.Co;2-0  0.351
1997 Kornblum HI, Hussain RJ, Bronstein JM, Gall CM, Lee DC, Seroogy KB. Prenatal ontogeny of the epidermal growth factor receptor and its ligand, transforming growth factor alpha, in the rat brain. The Journal of Comparative Neurology. 380: 243-61. PMID 9100135 DOI: 10.1002/(SICI)1096-9861(19970407)380:2<243::AID-CNE7>3.0.CO;2-3  0.363
1997 Kornblum HI, Sankar R, Shin DH, Wasterlain CG, Gall CM. Induction of brain derived neurotrophic factor mRNA by seizures in neonatal and juvenile rat brain. Brain Research. Molecular Brain Research. 44: 219-28. PMID 9073163 DOI: 10.1016/S0169-328X(96)00224-0  0.332
1995 Kornblum HI, Gall CM, Seroogy KB, Lauterborn JC. A subpopulation of striatal gabaergic neurons expresses the epidermal growth factor receptor. Neuroscience. 69: 1025-1029. PMID 8848092 DOI: 10.1016/0306-4522(95)00392-V  0.306
1995 Seroogy KB, Gall CM, Lee DC, Kornblum HI. Proliferative zones of postnatal rat brain express epidermal growth factor receptor mRNA. Brain Research. 670: 157-64. PMID 7719717 DOI: 10.1016/0006-8993(94)01300-7  0.372
1991 Loughlin SE, Kornblum HI, Massamiri T, Leslie FM. Transient appearance of beta-endorphin immunoreactive cells within the germinal zone of neonatal rat forebrain. International Journal of Developmental Neuroscience : the Official Journal of the International Society For Developmental Neuroscience. 9: 493-500. PMID 1664172 DOI: 10.1016/0736-5748(91)90035-K  0.548
1990 Kornblum HI, Corwin JT, Trevarrow B. Selective labeling of sensory hair cells and neurons in auditory, vestibular, and lateral line systems by a monoclonal antibody. The Journal of Comparative Neurology. 301: 162-70. PMID 2124588 DOI: 10.1002/cne.903010203  0.632
1990 Kornblum HI, Raymon HK, Morrison RS, Cavanaugh KP, Bradshaw RA, Leslie FM. Epidermal growth factor and basic fibroblast growth factor: effects on an overlapping population of neocortical neurons in vitro. Brain Research. 535: 255-63. PMID 2073605 DOI: 10.1016/0006-8993(90)91608-J  0.545
1990 Bradshaw RA, Altin JG, Blaber M, Cavanaugh KP, Eveleth DD, Kornblum HI, Leslie FM, Raffioni S. Neurotrophic factors in the CNS: biosynthetic processing and functional responses. Progress in Brain Research. 86: 157-67. PMID 1965051 DOI: 10.1016/S0079-6123(08)63174-X  0.591
1987 Kornblum HI, Loughlin SE, Leslie FM. Effects of morphine on DNA synthesis in neonatal rat brain. Brain Research. 428: 45-52. PMID 3815116 DOI: 10.1016/0165-3806(87)90081-2  0.531
1987 Morrison RS, Kornblum HI, Leslie FM, Bradshaw RA. Trophic stimulation of cultured neurons from neonatal rat brain by epidermal growth factor. Science (New York, N.Y.). 238: 72-5. PMID 3498986 DOI: 10.1126/Science.3498986  0.571
1987 Kornblum HI, Hurlbut DE, Leslie FM. Postnatal development of multiple opioid receptors in rat brain. Brain Research. 465: 21-41. PMID 2830947 DOI: 10.1016/0165-3806(87)90226-4  0.537
1985 Loughlin SE, Massamiri TR, Kornblum HI, Leslie FM. Postnatal development of opioid systems in rat brain. Neuropeptides. 5: 469-72. PMID 2987741 DOI: 10.1016/0143-4179(85)90056-3  0.55
Show low-probability matches.