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Xinkai Xie, Ph.D. - Publications

Affiliations: 
2010 University of California, Los Angeles, Los Angeles, CA 
Area:
natural product biosynthesis and biocatalysis
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16 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Feng Z, Pearce LV, Zhang Y, Xing C, Herold BK, Ma S, Hu Z, Turcios NA, Yang P, Tong Q, McCall AK, Blumberg PM, Xie XQ. Multi-Functional Diarylurea Small Molecule Inhibitors of TRPV1 with Therapeutic Potential for Neuroinflammation. The Aaps Journal. PMID 27000851 DOI: 10.1208/S12248-016-9888-Z  0.381
2016 Wang T, Xie XX, Ji M, Wang SW, Zha J, Zhou WW, Yu XL, Wei C, Ma S, Xi ZY, Pang GL, Liu RT. Naturally occurring autoantibodies against Aβ oligomers exhibited more beneficial effects in the treatment of mouse model of Alzheimer's disease than intravenous immunoglobulin. Neuropharmacology. PMID 26907803 DOI: 10.1016/j.neuropharm.2016.02.015  0.351
2015 Xu H, Ma S, Tang FY, Chen Y, Zhou H, Chen M, Wang B, Liu X, Xie X. Association between NAD(P)H oxidase p22phox gene variants and acute myocardial infarction in a Han Chinese population. Herz. PMID 26660092 DOI: 10.1007/s00059-015-4391-3  0.31
2012 Ames BD, Nguyen C, Bruegger J, Smith P, Xu W, Ma S, Wong E, Wong S, Xie X, Li JW, Vederas JC, Tang Y, Tsai SC. Crystal structure and biochemical studies of the trans-acting polyketide enoyl reductase LovC from lovastatin biosynthesis. Proceedings of the National Academy of Sciences of the United States of America. 109: 11144-9. PMID 22733743 DOI: 10.1073/Pnas.1113029109  0.587
2011 Meehan MJ, Xie X, Zhao X, Xu W, Tang Y, Dorrestein PC. FT-ICR-MS characterization of intermediates in the biosynthesis of the α-methylbutyrate side chain of lovastatin by the 277 kDa polyketide synthase LovF. Biochemistry. 50: 287-99. PMID 21069965 DOI: 10.1021/Bi1014776  0.428
2009 Ma SM, Li JW, Choi JW, Zhou H, Lee KK, Moorthie VA, Xie X, Kealey JT, Da Silva NA, Vederas JC, Tang Y. Complete reconstitution of a highly reducing iterative polyketide synthase. Science (New York, N.Y.). 326: 589-92. PMID 19900898 DOI: 10.1126/Science.1175602  0.59
2009 Gao X, Xie X, Pashkov I, Sawaya MR, Laidman J, Zhang W, Cacho R, Yeates TO, Tang Y. Directed evolution and structural characterization of a simvastatin synthase. Chemistry & Biology. 16: 1064-74. PMID 19875080 DOI: 10.1016/J.Chembiol.2009.09.017  0.651
2009 Xie X, Meehan MJ, Xu W, Dorrestein PC, Tang Y. Acyltransferase mediated polyketide release from a fungal megasynthase. Journal of the American Chemical Society. 131: 8388-9. PMID 19530726 DOI: 10.1021/Ja903203G  0.466
2009 Xie X, Pashkov I, Gao X, Guerrero JL, Yeates TO, Tang Y. Rational improvement of simvastatin synthase solubility in Escherichia coli leads to higher whole-cell biocatalytic activity. Biotechnology and Bioengineering. 102: 20-8. PMID 18988191 DOI: 10.1002/Bit.22028  0.576
2008 Zhou H, Xie X, Tang Y. Engineering natural products using combinatorial biosynthesis and biocatalysis. Current Opinion in Biotechnology. 19: 590-6. PMID 18992814 DOI: 10.1016/J.Copbio.2008.10.012  0.48
2008 Zhou H, Zhan J, Watanabe K, Xie X, Tang Y. A polyketide macrolactone synthase from the filamentous fungus Gibberella zeae. Proceedings of the National Academy of Sciences of the United States of America. 105: 6249-54. PMID 18427109 DOI: 10.1073/Pnas.0800657105  0.47
2008 Ma SM, Zhan J, Xie X, Watanabe K, Tang Y, Zhang W. Redirecting the cyclization steps of fungal polyketide synthase. Journal of the American Chemical Society. 130: 38-9. PMID 18072779 DOI: 10.1021/Ja078091O  0.615
2007 Ma SM, Zhan J, Watanabe K, Xie X, Zhang W, Wang CC, Tang Y. Enzymatic synthesis of aromatic polyketides using PKS4 from Gibberella fujikuroi. Journal of the American Chemical Society. 129: 10642-3. PMID 17696354 DOI: 10.1021/Ja074865P  0.6
2007 Xie X, Wong WW, Tang Y. Improving simvastatin bioconversion in Escherichia coli by deletion of bioH. Metabolic Engineering. 9: 379-86. PMID 17625941 DOI: 10.1016/J.Ymben.2007.05.006  0.471
2007 Xie X, Tang Y. Efficient synthesis of simvastatin by use of whole-cell biocatalysis. Applied and Environmental Microbiology. 73: 2054-60. PMID 17277201 DOI: 10.1128/AEM.02820-06  0.383
2006 Xie X, Watanabe K, Wojcicki WA, Wang CC, Tang Y. Biosynthesis of lovastatin analogs with a broadly specific acyltransferase. Chemistry & Biology. 13: 1161-9. PMID 17113998 DOI: 10.1016/J.Chembiol.2006.09.008  0.501
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