| Year |
Citation |
Score |
| 2023 |
Guimarães NSS, Ramos VS, Prado-Souza LFL, Lopes RM, Arini GS, Feitosa LGP, Silva RR, Nantes IL, Damasceno DC, Lopes NP, Rodrigues T. Rosemary ( L.) Glycolic Extract Protects Liver Mitochondria from Oxidative Damage and Prevents Acetaminophen-Induced Hepatotoxicity. Antioxidants (Basel, Switzerland). 12. PMID 36978874 DOI: 10.3390/antiox12030628 |
0.336 |
|
| 2022 |
Moraes VWR, Santos VM, Suarez ER, Ferraz LS, Lopes RM, Mognol GP, Campeiro JD, Machado-Neto JA, Nascimento FD, Hayashi MAF, Tersariol ILS, Newmeyer DD, Rodrigues T. Targeting Ca and Mitochondrial Homeostasis by Antipsychotic Thioridazine in Leukemia Cells. Life (Basel, Switzerland). 12. PMID 36294912 DOI: 10.3390/life12101477 |
0.352 |
|
| 2022 |
Bonturi CR, Salu BR, Bonazza CN, Sinigaglia RC, Rodrigues T, Alvarez-Flores MP, Chudzinski-Tavassi AM, Oliva MLV. Proliferation and Invasion of Melanoma Are Suppressed by a Plant Protease Inhibitor, Leading to Downregulation of Survival/Death-Related Proteins. Molecules (Basel, Switzerland). 27. PMID 35566311 DOI: 10.3390/molecules27092956 |
0.307 |
|
| 2020 |
Rodrigues T, Ferraz LS. Therapeutic potential of targeting mitochondrial dynamics in cancer. Biochemical Pharmacology. 182: 114282. PMID 33058754 DOI: 10.1016/j.bcp.2020.114282 |
0.32 |
|
| 2020 |
Porta LC, Campeiro JD, Papa GB, Oliveira EB, Godinho RO, Rodrigues T, Hayashi MAF. In vivo effects of the association of the psychoactive phenotiazine thioridazine on antitumor activity and hind limb paralysis induced by the native polypeptide crotamine. Toxicon : Official Journal of the International Society On Toxinology. 185: 64-71. PMID 32621838 DOI: 10.1016/J.Toxicon.2020.06.017 |
0.304 |
|
| 2020 |
Silva Ferraz L, Torres da Costa R, Alves da Costa C, Augusto João Ribeiro C, Costa Arruda D, Stuchi Maria-Engler S, Rodrigues T. Targeting mitochondria in melanoma: interplay between MAPK signaling pathway and mitochondrial dynamics. Biochemical Pharmacology. 114104. PMID 32562785 DOI: 10.1016/J.Bcp.2020.114104 |
0.393 |
|
| 2020 |
Costa CA, Lopes RM, Ferraz LS, Esteves GNN, Di Iorio JF, Souza AA, de Oliveira IM, Manarin F, Judice WAS, Stefani HA, Rodrigues T. Cytotoxicity of 4-substituted quinoline derivatives: Anticancer and antileishmanial potential. Bioorganic & Medicinal Chemistry. 115511. PMID 32336669 DOI: 10.1016/J.Bmc.2020.115511 |
0.457 |
|
| 2020 |
do Carmo AL, Bettanin F, Oliveira Almeida M, Pantaleão SQ, Rodrigues T, Homem-de-Mello P, Honorio KM. Competition Between Phenothiazines and BH3 Peptide for the Binding Site of the Antiapoptotic BCL-2 Protein. Frontiers in Chemistry. 8: 235. PMID 32309275 DOI: 10.3389/Fchem.2020.00235 |
0.334 |
|
| 2019 |
Medeiros HCD, Colturato-Kido C, Ferraz LS, Costa CA, Moraes VWR, Paredes-Gamero EJ, Tersariol ILS, Rodrigues T. AMPK activation induced by promethazine increases NOXA expression and Beclin-1 phosphorylation and drives autophagy-associated apoptosis in chronic myeloid leukemia. Chemico-Biological Interactions. 315: 108888. PMID 31682805 DOI: 10.1016/J.Cbi.2019.108888 |
0.368 |
|
| 2018 |
Vital WD, Torquato HFV, Jesus LOP, Judice WAS, Silva MFDGFD, Rodrigues T, Justo GZ, Veiga TAM, Paredes-Gamero EJ. 4-Deoxyraputindole C induces cell death and cell cycle arrest in tumor cell lines. Journal of Cellular Biochemistry. PMID 30525230 DOI: 10.1002/Jcb.28238 |
0.393 |
|
| 2018 |
Ferraz LS, Watashi CM, Colturato-Kido C, Pelegrino MT, Paredes-Gamero EJ, Weller RB, Seabra AB, Rodrigues T. Antitumor potential of S-nitrosothiol-containing polymeric nanoparticles against melanoma. Molecular Pharmaceutics. PMID 29378125 DOI: 10.1021/Acs.Molpharmaceut.7B01001 |
0.378 |
|
| 2017 |
Lucena SV, Moura GEDD, Rodrigues T, Watashi CM, Melo FHM, Icimoto MY, Viana GM, Nader HB, Monteiro HP, Tersariol ILS, Ogata FT. Heparan Sulfate Proteoglycan Deficiency Up-Regulates the Intracellular Production of Nitric Oxide in Chinese Hamster Ovary Cell Lines. Journal of Cellular Physiology. PMID 28833096 DOI: 10.1002/Jcp.26160 |
0.362 |
|
| 2017 |
de Figueiredo LP, Ibiapino AL, do Amaral DN, Ferraz LS, Rodrigues T, Barreiro EJ, Lima LM, Ferreira FF. Structural characterization and cytotoxicity studies of different forms of a combretastatin A4 analogue Journal of Molecular Structure. 1147: 226-234. DOI: 10.1016/J.Molstruc.2017.06.093 |
0.318 |
|
| 2016 |
de Mello JC, Moraes VW, Watashi CM, Silva DC, Cavalcanti LP, Franco MK, Yokaichiya F, Araujo DR, Rodrigues T. Enhancement of chlorpromazine antitumor activity by Pluronics F127/L81 nanostructured system against human multidrug resistant leukemia. Pharmacological Research. PMID 27265114 DOI: 10.1016/J.Phrs.2016.05.032 |
0.301 |
|
| 2016 |
Jabes DL, de Freitas Oliveira AC, Alencar VC, Menegidio FB, Reno DL, Santos DS, Barbosa DA, Vilas Boas RO, de Oliveira Rodrigues Cunha RL, Rodrigues T, Costa de Oliveira R, Nunes LR. Thioridazine inhibits gene expression control of the cell wall signaling pathway (CWI) in the human pathogenic fungus Paracoccidioides brasiliensis. Molecular Genetics and Genomics : Mgg. 291: 1347-62. PMID 26956010 DOI: 10.1007/S00438-016-1184-1 |
0.306 |
|
| 2015 |
Mello JC, Gonzalez MV, Moraes VW, Prieto T, Nascimento OR, Rodrigues T. Protective Effect of Plantago major Extract against t-BOOH-Induced Mitochondrial Oxidative Damage and Cytotoxicity. Molecules (Basel, Switzerland). 20: 17747-59. PMID 26404215 DOI: 10.3390/Molecules201017747 |
0.389 |
|
| 2015 |
de Faria PA, Bettanin F, Cunha RL, Paredes-Gamero EJ, Homem-de-Mello P, Nantes IL, Rodrigues T. Cytotoxicity of phenothiazine derivatives associated with mitochondrial dysfunction: a structure-activity investigation. Toxicology. 330: 44-54. PMID 25686698 DOI: 10.1016/J.Tox.2015.02.004 |
0.639 |
|
| 2013 |
Moraes VWR, Caires ACF, Paredes-Gamero EJ, Rodrigues T. Organopalladium compound 7b targets mitochondrial thiols and induces caspase-dependent apoptosis in human myeloid leukemia cells Cell Death and Disease. 4: 0. PMID 23744358 DOI: 10.1038/Cddis.2013.190 |
0.411 |
|
| 2012 |
Mello JC, Guimarães NS, Gonzalez MV, Paiva JS, Prieto T, Nascimento OR, Rodrigues T. Hydroxyl scavenging activity accounts for differential antioxidant protection of Plantago major against oxidative toxicity in isolated rat liver mitochondria. The Journal of Pharmacy and Pharmacology. 64: 1177-87. PMID 22775221 DOI: 10.1111/J.2042-7158.2012.01496.X |
0.356 |
|
| 2012 |
Guimarães NS, Mello JC, Paiva JS, Bueno PC, Berretta AA, Torquato RJ, Nantes IL, Rodrigues T. Baccharis dracunculifolia, the main source of green propolis, exhibits potent antioxidant activity and prevents oxidative mitochondrial damage. Food and Chemical Toxicology : An International Journal Published For the British Industrial Biological Research Association. 50: 1091-7. PMID 22119782 DOI: 10.1016/J.Fct.2011.11.014 |
0.426 |
|
| 2012 |
Afonso de Faria P, Santos Rosa Td, Sola Haro A, Soares Trindade A, Suemitsu Higa EM, Rodrigues T. Obesity Promotes Oxidative Stress and Increased Susceptibility to Mitochondrial Permeabilization in Zucker Rat Free Radical Biology and Medicine. 53: S95. DOI: 10.1016/J.Freeradbiomed.2012.10.171 |
0.34 |
|
| 2011 |
Serrano FA, Matsuo AL, Monteforte PT, Bechara A, Smaili SS, Santana DP, Rodrigues T, Pereira FV, Silva LS, Machado J, Santos EL, Pesquero JB, Martins RM, Travassos LR, Caires AC, et al. A cyclopalladated complex interacts with mitochondrial membrane thiol-groups and induces the apoptotic intrinsic pathway in murine and cisplatin-resistant human tumor cells. Bmc Cancer. 11: 296. PMID 21756336 DOI: 10.1186/1471-2407-11-296 |
0.355 |
|
| 2011 |
Nantes IL, Rodrigues T, Caires AC, Cunha RL, Pessoto FS, Yokomizo CH, Araujo-Chaves JC, Faria PA, Santana DP, dos Santos CG. Specific effects of reactive thiol drugs on mitochondrial bioenergetics. Journal of Bioenergetics and Biomembranes. 43: 11-8. PMID 21279427 DOI: 10.1007/S10863-011-9328-9 |
0.648 |
|
| 2011 |
Borges MB, Dos Santos CG, Yokomizo CH, Sood R, Vitovic P, Kinnunen PK, Rodrigues T, Nantes IL. Characterization of hydrophobic interaction and antioxidant properties of the phenothiazine nucleus in mitochondrial and model membranes. Free Radical Research. 44: 1054-63. PMID 20815768 DOI: 10.3109/10715762.2010.498826 |
0.426 |
|
| 2010 |
Cruz TS, Faria PA, Santana DP, Ferreira JC, Oliveira V, Nascimento OR, Cerchiaro G, Curti C, Nantes IL, Rodrigues T. On the mechanisms of phenothiazine-induced mitochondrial permeability transition: Thiol oxidation, strict Ca2+ dependence, and cyt c release. Biochemical Pharmacology. 80: 1284-95. PMID 20619250 DOI: 10.1016/J.Bcp.2010.06.052 |
0.469 |
|
| 2010 |
dos Santos CG, Borges MB, Baptista MdS, Itri R, Rodrigues T, Nantes IL. The Nanoparticle Photogenerated by Association of Phenothiazine Nucleus to Poly(ethylene glycol) Protects Photodamage in Mitochondrial Membrane Unsaturated Lipids Free Radical Biology and Medicine. 49: S180. DOI: 10.1016/J.Freeradbiomed.2010.10.513 |
0.351 |
|
| 2010 |
Faria PAd, Nantes IL, Rodrigues T. Thiol Oxidation and Mitochondrial Potential Disruption is Involved in the Phenothiazine-Induced HepG2 Cell Death Free Radical Biology and Medicine. 49. DOI: 10.1016/J.Freeradbiomed.2010.10.136 |
0.444 |
|
| 2009 |
Kawai C, Pessoto FS, Rodrigues T, Mugnol KC, Tórtora V, Castro L, Milícchio VA, Tersariol IL, Di Mascio P, Radi R, Carmona-Ribeiro AM, Nantes IL. pH-sensitive binding of cytochrome c to the inner mitochondrial membrane. Implications for the participation of the protein in cell respiration and apoptosis. Biochemistry. 48: 8335-42. PMID 19650668 DOI: 10.1021/Bi9006463 |
0.329 |
|
| 2009 |
Oliveira CR, Barbosa CM, Nascimento FD, Lanetzki CS, Meneghin MB, Pereira FE, Paredes-Gamero EJ, Ferreira AT, Rodrigues T, Queiroz ML, Caires AC, Tersariol IL, Bincoletto C. Pre-clinical antitumour evaluation of Biphosphinic Palladacycle Complex in human leukaemia cells. Chemico-Biological Interactions. 177: 181-9. PMID 19026616 DOI: 10.1016/J.Cbi.2008.10.034 |
0.394 |
|
| 2009 |
Santana DP, Faria PA, Paredes-Gamero EJ, Caires AC, Nantes IL, Rodrigues T. Palladacycles catalyse the oxidation of critical thiols of the mitochondrial membrane proteins and lead to mitochondrial permeabilization and cytochrome c release associated with apoptosis. The Biochemical Journal. 417: 247-56. PMID 18752468 DOI: 10.1042/Bj20080972 |
0.487 |
|
| 2008 |
Dorta DJ, Pigoso AA, Mingatto FE, Rodrigues T, Pestana CR, Uyemura SA, Santos AC, Curti C. Antioxidant activity of flavonoids in isolated mitochondria. Phytotherapy Research : Ptr. 22: 1213-8. PMID 18729257 DOI: 10.1002/Ptr.2441 |
0.433 |
|
| 2007 |
Pessoto FS, Faria PA, Cunha RL, Comasseto JV, Rodrigues T, Nantes IL. Organotellurane-promoted mitochondrial permeability transition concomitant with membrane lipid protection against oxidation. Chemical Research in Toxicology. 20: 1453-61. PMID 17896819 DOI: 10.1021/Tx700092R |
0.638 |
|
| 2007 |
Rodrigues T, de França LP, Kawai C, de Faria PA, Mugnol KC, Braga FM, Tersariol IL, Smaili SS, Nantes IL. Protective role of mitochondrial unsaturated lipids on the preservation of the apoptotic ability of cytochrome C exposed to singlet oxygen. The Journal of Biological Chemistry. 282: 25577-87. PMID 17567586 DOI: 10.1074/Jbc.M700009200 |
0.349 |
|
| 2006 |
Cálgaro-Helena AF, Devienne KF, Rodrigues T, Dorta DJ, Raddi MS, Vilegas W, Uyemura SA, Santos AC, Curti C. Effects of isocoumarins isolated from Paepalanthus bromelioides on mitochondria: uncoupling, and induction/inhibition of mitochondrial permeability transition. Chemico-Biological Interactions. 161: 155-64. PMID 16716282 DOI: 10.1016/J.Cbi.2006.04.006 |
0.459 |
|
| 2005 |
Dorta DJ, Pigoso AA, Mingatto FE, Rodrigues T, Prado IM, Helena AF, Uyemura SA, Santos AC, Curti C. The interaction of flavonoids with mitochondria: effects on energetic processes. Chemico-Biological Interactions. 152: 67-78. PMID 15840381 DOI: 10.1016/J.Cbi.2005.02.004 |
0.439 |
|
| 2003 |
Dorta DJ, Leite S, DeMarco KC, Prado IM, Rodrigues T, Mingatto FE, Uyemura SA, Santos AC, Curti C. A proposed sequence of events for cadmium-induced mitochondrial impairment. Journal of Inorganic Biochemistry. 97: 251-7. PMID 14511887 DOI: 10.1016/S0162-0134(03)00314-3 |
0.446 |
|
| 2002 |
Mingatto FE, Rodrigues T, Pigoso AA, Uyemura SA, Curti C, Santos AC. The critical role of mitochondrial energetic impairment in the toxicity of nimesulide to hepatocytes. The Journal of Pharmacology and Experimental Therapeutics. 303: 601-7. PMID 12388641 DOI: 10.1124/Jpet.102.038620 |
0.428 |
|
| 2002 |
Rodrigues T, Santos AC, Pigoso AA, Mingatto FE, Uyemura SA, Curti C. Thioridazine interacts with the membrane of mitochondria acquiring antioxidant activity toward apoptosis--potentially implicated mechanisms. British Journal of Pharmacology. 136: 136-42. PMID 11976278 DOI: 10.1038/Sj.Bjp.0704672 |
0.469 |
|
| 2000 |
Mingatto FE, Santos ACD, Rodrigues T, Pigoso AA, Uyemura SA, Curti C. Effects of nimesulide and its reduced metabolite on mitochondria British Journal of Pharmacology. 131: 1154-1160. PMID 11082123 DOI: 10.1038/Sj.Bjp.0703667 |
0.43 |
|
| 1998 |
Pigoso AA, Uyemura SA, Santos AC, Rodrigues T, Mingatto FE, Curti C. Influence of nonsteroidal anti-inflammatory drugs on calcium efflux in isolated rat renal cortex mitochondria and aspects of the mechanisms involved. The International Journal of Biochemistry & Cell Biology. 30: 961-965. PMID 9785459 DOI: 10.1016/S1357-2725(98)00030-2 |
0.322 |
|
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