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Matt J. Merrins, Ph.D. - Publications

Affiliations: 
Pharmacology University of Michigan, Ann Arbor, Ann Arbor, MI 
Area:
Beta cell metabolism, oscillations
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26 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 de Souza AH, Tang J, Yadev AK, Saghafi ST, Kibbe CR, Linnemann AK, Merrins MJ, Davis DB. Intra-islet GLP-1, but not CCK, is necessary for β-cell function in mouse and human islets. Scientific Reports. 10: 2823. PMID 32071395 DOI: 10.1038/S41598-020-59799-2  0.447
2019 Douros JD, Niu J, Sdao S, Gregg T, Merrins MJ, Campbell J, Tong J, D'Alessio D. Temporal plasticity of insulin and incretin secretion and insulin sensitivity following sleeve gastrectomy contribute to sustained improvements in glucose control. Molecular Metabolism. PMID 31326351 DOI: 10.1016/J.Molmet.2019.07.003  0.388
2019 Douros JD, Niu J, Sdao SM, Gregg T, Fisher-Wellman KH, Bharadwaj MS, Molina A, Arumugam R, Martin MD, Petretto E, Merrins MJ, Herman MA, Tong J, Campbell JE, D'Alessio D. Sleeve gastrectomy rapidly enhances islet function independently of body weight. Jci Insight. PMID 30777938 DOI: 10.1172/Jci.Insight.126688  0.417
2019 Capozzi ME, Svendsen B, Encisco SE, Lewandowski SL, Martin MD, Lin H, Jaffe JL, Coch RW, Haldeman JM, MacDonald PE, Merrins MJ, D'Alessio DA, Campbell JE. β-Cell tone is defined by proglucagon peptides through cyclic AMP signaling. Jci Insight. PMID 30720465 DOI: 10.1172/jci.insight.126742  0.458
2018 De Leon ER, Brinkman JA, Fenske RJ, Gregg T, Schmidt BA, Sherman DS, Cummings NE, Peter DC, Kimple ME, Lamming DW, Merrins MJ. Age-Dependent Protection of Insulin Secretion in Diet Induced Obese Mice. Scientific Reports. 8: 17814. PMID 30546031 DOI: 10.1038/S41598-018-36289-0  0.318
2018 Hennings TG, Chopra DG, DeLeon ER, VanDeusen HR, Sesaki H, Merrins MJ, Ku GM. In vivo Deletion of Beta Cell Drp1 Impairs Insulin Secretion without Affecting Islet Oxygen Consumption. Endocrinology. PMID 30052866 DOI: 10.1210/En.2018-00445  0.624
2018 LEWANDOWSKI SL, MERRINS MJ. Glucose Oxidation Depletes Cytosolic Citrate and Glutamate in the Amplifying Pathways of Insulin Secretion Diabetes. 67: 2152-P. DOI: 10.2337/db18-2152-P  0.373
2018 SDAO S, POUDEL C, MORTENSEN KM, MERRINS MJ. Cdk2-Dependent Activation of ß-Cell Metabolism Is Eclipsed by Its Inhibitory Effect on Plasma Membrane Excitability and Insulin Secretion Diabetes. 67: 2140-P. DOI: 10.2337/db18-2140-P  0.381
2017 Neuman JC, Schaid MD, Brill AL, Fenske RJ, Kibbe CR, Fontaine DA, Sdao SM, Brar HK, Connors KM, Wienkes HN, Eliceiri KW, Merrins MJ, Davis DB, Kimple ME. Enriching Islet Phospholipids with Eicosapentaenoic Acid Reduces Prostaglandin E2 Signaling and Enhances Diabetic β-cell Function. Diabetes. PMID 28193789 DOI: 10.2337/Db16-1362  0.359
2017 Kim SY, Lee JH, Merrins MJ, Gavrilova O, Bisteau X, Kaldis P, Satin LS, Rane SG. Loss of Cyclin Dependent Kinase 2 in the Pancreas Links Primary β-cell Dysfunction to Progressive Depletion of β-cell Mass and Diabetes. The Journal of Biological Chemistry. PMID 28100774 DOI: 10.1074/jbc.M116.754077  0.306
2016 Gregg T, Poudel C, Schmidt BA, Dhillon RS, Sdao SM, Truchan NA, Baar EL, Fernandez LA, Denu JM, Eliceiri KW, Rogers JD, Kimple ME, Lamming DW, Merrins MJ. Pancreatic β cells from Mice Offset Age-Associated Mitochondrial Deficiency with Reduced KATP Channel Activity. Diabetes. PMID 27284112 DOI: 10.2337/Db16-0432  0.406
2016 McKenna JP, Ha J, Merrins MJ, Satin LS, Sherman A, Bertram R. Ca(2+) Effects on ATP Production and Consumption Have Regulatory Roles on Oscillatory Islet Activity. Biophysical Journal. 110: 733-742. PMID 26840737 DOI: 10.1016/J.Bpj.2015.11.3526  0.392
2016 Merrins MJ, Poudel C, McKenna JP, Ha J, Sherman A, Bertram R, Satin LS. Phase Analysis of Metabolic Oscillations and Membrane Potential in Pancreatic Islet β-Cells. Biophysical Journal. 110: 691-699. PMID 26840733 DOI: 10.1016/J.Bpj.2015.12.029  0.315
2016 Poudel C, Schmidt BA, Harenda QE, Engin F, Eliceiri KW, Merrins MJ. TUDCA Rescues γ-Cell Metabolic Oscillations from ER Stress, Revealed By NAD(P)H-FLIM and FRET Biophysical Journal. 110: 142a-143a. DOI: 10.1016/J.Bpj.2015.11.810  0.311
2014 Watts M, Fendler B, Merrins MJ, Satin LS, Bertram R, Sherman A. Calcium and Metabolic Oscillations in Pancreatic Islets: Who's Driving the Bus?(*) Siam Journal On Applied Dynamical Systems. 13: 683-703. PMID 25698909 DOI: 10.1137/130920198  0.318
2014 Johnson JS, Kono T, Tong X, Yamamoto WR, Zarain-Herzberg A, Merrins MJ, Satin LS, Gilon P, Evans-Molina C. Pancreatic and duodenal homeobox protein 1 (Pdx-1) maintains endoplasmic reticulum calcium levels through transcriptional regulation of sarco-endoplasmic reticulum calcium ATPase 2b (SERCA2b) in the islet β cell. The Journal of Biological Chemistry. 289: 32798-810. PMID 25271154 DOI: 10.1074/Jbc.M114.575191  0.305
2014 Alejandro EU, Gregg B, Wallen T, Kumusoglu D, Meister D, Chen A, Merrins MJ, Satin LS, Liu M, Arvan P, Bernal-Mizrachi E. Maternal diet-induced microRNAs and mTOR underlie β cell dysfunction in offspring. The Journal of Clinical Investigation. 124: 4395-410. PMID 25180600 DOI: 10.1172/JCI74237  0.389
2014 Merrins MJ, Satin LS. Ca2+ has a Permissive Effect on Glycolytic Oscillations in Pancreatic Beta Cells Biophysical Journal. 106: 526a. DOI: 10.1016/j.bpj.2013.11.2937  0.551
2013 Merrins MJ, Van Dyke AR, Mapp AK, Rizzo MA, Satin LS. Direct measurements of oscillatory glycolysis in pancreatic islet β-cells using novel fluorescence resonance energy transfer (FRET) biosensors for pyruvate kinase M2 activity. The Journal of Biological Chemistry. 288: 33312-22. PMID 24100037 DOI: 10.1074/Jbc.M113.508127  0.375
2013 Merrins MJ, Kim SY, Rane SG, Satin LS. Cyclin Dependent Kinase 2 (CDK2) Regulates Secretory Function in Pancreatic Beta-Cells Biophysical Journal. 104: 621a. DOI: 10.1016/j.bpj.2012.11.3435  0.496
2012 Merrins MJ, Bertram R, Sherman A, Satin LS. Phosphofructo-2-kinase/fructose-2,6-bisphosphatase modulates oscillations of pancreatic islet metabolism. Plos One. 7: e34036. PMID 22532827 DOI: 10.1371/Journal.Pone.0034036  0.451
2012 Merrins MJ, Satin LS. A Novel FRET Biosensor For Measuring Glycolytic Activity: A Study of Pancreatic Beta-Cells Biophysical Journal. 102: 199a. DOI: 10.1016/j.bpj.2011.11.1084  0.536
2011 Merrins M, Bertram R, Sherman A, Satin L. Testing a Computational Model of Pancreatic Beta-Cell Oscillations Using Live-Cell Imaging of Islet Oscillatory Behavior Microscopy and Microanalysis. 17: 208-209. DOI: 10.1017/S1431927611001917  0.425
2011 Merrins MJ, Bertram R, Sherman A, Satin LS. 6-Phosphofructo-2-Kinase/Fructose-2,6-Bisphosphatase (PFKFB) Modulates Slow Oscillations in Pancreatic Islets Biophysical Journal. 100: 380a-381a. DOI: 10.1016/J.Bpj.2010.12.2265  0.416
2010 Merrins MJ, Fendler B, Zhang M, Sherman A, Bertram R, Satin LS. Metabolic oscillations in pancreatic islets depend on the intracellular Ca2+ level but not Ca2+ oscillations. Biophysical Journal. 99: 76-84. PMID 20655835 DOI: 10.1016/J.Bpj.2010.04.012  0.308
2009 Nunemaker CS, Dishinger JF, Dula SB, Wu R, Merrins MJ, Reid KR, Sherman A, Kennedy RT, Satin LS. Glucose metabolism, islet architecture, and genetic homogeneity in imprinting of [Ca2+](i) and insulin rhythms in mouse islets. Plos One. 4: e8428. PMID 20037650 DOI: 10.1371/Journal.Pone.0008428  0.469
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