Yahua Liu, Ph.D.

2001 Case Western Reserve University, Cleveland Heights, OH, United States 
"Yahua Liu"


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Lawrence M. Sayre grad student 2001 Case Western
 (Selected aspects of protein cross -linking by oxidation and aldehyde modification.)
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Liu Y, Zhang W, Sayre LM. (2011) An alternative total synthesis of pentosidine Journal of Heterocyclic Chemistry. 48: 426-433
Liu Y, Zhang W, Sayre LM. (2010) A straightforward synthesis of pentosidine framework Journal of Heterocyclic Chemistry. 47: 683-686
Liu Y, Sun G, David A, et al. (2004) Model studies on the metal-catalyzed protein oxidation: structure of a possible His-Lys cross-link. Chemical Research in Toxicology. 17: 110-8
Liu Y, Xu G, Sayre LM. (2003) Carnosine inhibits (E)-4-hydroxy-2-nonenal-induced protein cross-linking: structural characterization of carnosine-HNE adducts. Chemical Research in Toxicology. 16: 1589-97
Xu G, Liu Y, Sayre LM. (2000) Polyclonal antibodies to a fluorescent 4-hydroxy-2-nonenal (HNE)-derived lysine-lysine cross-link: characterization and application to HNE-treated protein and in vitro oxidized low-density lipoprotein. Chemical Research in Toxicology. 13: 406-13
Sayre LM, Perry G, Harris PL, et al. (2000) In situ oxidative catalysis by neurofibrillary tangles and senile plaques in Alzheimer's disease: a central role for bound transition metals. Journal of Neurochemistry. 74: 270-9
Xu G, Liu Y, Kansal MM, et al. (1999) Rapid cross-linking of proteins by 4-ketoaldehydes and 4-hydroxy-2-alkenals does not arise from the lysine-derived monoalkylpyrroles. Chemical Research in Toxicology. 12: 855-61
Xu G, Liu Y, Sayre LM. (1999) Independent synthesis, solution behavior, and studies on the mechanism of formation of a primary amine-derived fluorophore representing cross- linking of proteins by (E)-4-hydroxy-2-nonenal Journal of Organic Chemistry. 64: 5732-5745
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