Chunhua Qiao, Ph.D.

Affiliations: 
2004 Case Western Reserve University, Cleveland Heights, OH, United States 
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"Chunhua Qiao"

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Lawrence M. Sayre grad student 2004 Case Western
 (New copper amine oxidase probes: Synthesis, mechanism, and enzymology.)
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Liu L, Kong C, Fumagalli M, et al. (2020) Design, synthesis and evaluation of covalent inhibitors of DprE1 as antitubercular agents. European Journal of Medicinal Chemistry. 208: 112773
Xu Z, Yin W, Martinelli LK, et al. (2014) Reaction intermediate analogues as bisubstrate inhibitors of pantothenate synthetase. Bioorganic & Medicinal Chemistry. 22: 1726-35
Qiao C, Gupte A, Boshoff HI, et al. (2007) 5'-O-[(N-acyl)sulfamoyl]adenosines as antitubercular agents that inhibit MbtA: an adenylation enzyme required for siderophore biosynthesis of the mycobactins. Journal of Medicinal Chemistry. 50: 6080-94
Qiao C, Ling KQ, Shepard EM, et al. (2006) Mechanism-based cofactor derivatization of a copper amine oxidase by a branched primary amine recruits the oxidase activity of the enzyme to turn inactivator into substrate. Journal of the American Chemical Society. 128: 6206-19
Lamplot Z, Sebela M, Malon M, et al. (2004) 1,5-diamino-2-pentyne is both a substrate and inactivator of plant copper amine oxidases. European Journal of Biochemistry / Febs. 271: 4696-708
Qiao C, Jeon HB, Sayre LM. (2004) Selective inhibition of bovine plasma amine oxidase by homopropargylamine, a new inactivator motif. Journal of the American Chemical Society. 126: 8038-45
Jeon HB, Lee Y, Qiao C, et al. (2003) Inhibition of bovine plasma amine oxidase by 1,4-diamino-2-butenes and -2-butynes. Bioorganic & Medicinal Chemistry. 11: 4631-41
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