Holly M. Brothers

Ohio State University, Columbus, Columbus, OH 
Alzheimer's disease
"Holly Brothers"
Cross-listing: Neurotree


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Gary  G. Berntson research assistant 2003-2005 Ohio State (Neurotree)
A Courtney DeVries research assistant 2005-2005 Ohio State (Neurotree)
Gary L. Wenk grad student 2005-2013 Ohio State (Neurotree)
 (Neuroinflammation, Glutamate Regulation and Memory.)


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Roxanne Kaercher collaborator Ohio State
Yannick Marchalant collaborator 2005-2010 Ohio State (Neurotree)
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Latta CH, Sudduth TL, Weekman EM, et al. (2015) Determining the role of IL-4 induced neuroinflammation in microglial activity and amyloid-β using BV2 microglial cells and APP/PS1 transgenic mice. Journal of Neuroinflammation. 12: 41
Latta CH, Brothers HM, Wilcock DM. (2014) Neuroinflammation in Alzheimer's disease; A source of heterogeneity and target for personalized therapy. Neuroscience
Weekman EM, Sudduth TL, Abner EL, et al. (2014) Transition from an M1 to a mixed neuroinflammatory phenotype increases amyloid deposition in APP/PS1 transgenic mice. Journal of Neuroinflammation. 11: 127
Sudduth TL, Weekman EM, Brothers HM, et al. (2014) β-amyloid deposition is shifted to the vasculature and memory impairment is exacerbated when hyperhomocysteinemia is induced in APP/PS1 transgenic mice. Alzheimer's Research & Therapy. 6: 32
Hopp SC, Royer S, Brothers HM, et al. (2014) Age-associated alterations in the time-dependent profile of pro- and anti-inflammatory proteins within the hippocampus in response to acute exposure to interleukin-1β. Journal of Neuroimmunology. 267: 86-91
Bardou I, Kaercher RM, Brothers HM, et al. (2014) Age and duration of inflammatory environment differentially affect the neuroimmune response and catecholaminergic neurons in the midbrain and brainstem. Neurobiology of Aging. 35: 1065-73
Brothers HM, Bardou I, Hopp SC, et al. (2013) Time-Dependent Compensatory Responses to Chronic Neuroinflammation in Hippocampus and Brainstem: The Potential Role of Glutamate Neurotransmission. Journal of Alzheimer's Disease & Parkinsonism. 3: 110
Brothers HM, Bardou I, Hopp SC, et al. (2013) Riluzole partially rescues age-associated, but not LPS-induced, loss of glutamate transporters and spatial memory. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. 8: 1098-105
Bardou I, Brothers HM, Kaercher RM, et al. (2013) Differential effects of duration and age on the consequences of neuroinflammation in the hippocampus. Neurobiology of Aging. 34: 2293-301
Cerbai F, Lana D, Nosi D, et al. (2012) The neuron-astrocyte-microglia triad in normal brain ageing and in a model of neuroinflammation in the rat hippocampus. Plos One. 7: e45250
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