Robert A. Durham

Affiliations: 
Pfizer, Inc., San Diego, CA, United States 
Area:
Alzheimer's, drug discovery
Google:
"Robert Durham"
Cross-listing: Neurotree

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Publications

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Wood KM, McCush F, Conboy JJ, et al. (2010) IP/MS analysis of human CSF Aβ following a single dose of the C-terminal anti-Aβ antibody ponezumab (PF-04360365) to Alzheimer patients Alzheimers & Dementia. 6
Wang EQ, Wentland J, Rajadhyaksha M, et al. (2009) P3-273: Pharmacokinetic and pharmacodynamic evaluation of PF-04360365, a humanized monoclonal anti-amyloid antibody, in young and aged cynomolgus monkeys Alzheimer's & Dementia. 5: P423-P423
Conboy JJ, Wood KG, Lame ME, et al. (2008) Modification of amyloid-beta(1-40) by a protease inhibitor creates risk of error in mass spectrometric quantitation of amyloid-beta(1-42). Analytical Biochemistry. 382: 147-9
Beach TG, Walker DG, Potter PE, et al. (2005) Cortical cholinergic deafferentation induces aβ deposition toward a physiological animal model of alzheimer's disease Molecular Neurosurgery With Targeted Toxins. 143-180
Sunderland T, Mirza N, Putnam KT, et al. (2004) Cerebrospinal fluid beta-amyloid1-42 and tau in control subjects at risk for Alzheimer's disease: the effect of APOE epsilon4 allele. Biological Psychiatry. 56: 670-6
Cataldo AM, Petanceska S, Terio NB, et al. (2004) Abeta localization in abnormal endosomes: association with earliest Abeta elevations in AD and Down syndrome. Neurobiology of Aging. 25: 1263-72
Beach TG, Walker DG, Sue LI, et al. (2003) Immunotoxin Lesion of the Cholinergic Nucleus Basalis Causes Aβ Deposition: Towards a Physiologic Animal Model of Alzheimers Disease Current Medicinal Chemistry - Immunology, Endocrine & Metabolic Agents. 3: 57-75
Walker LC, Bian F, Callahan MJ, et al. (2002) Modeling Alzheimer's disease and other proteopathies in vivo: is seeding the key? Amino Acids. 23: 87-93
Walker LC, Callahan MJ, Bian F, et al. (2002) Exogenous induction of cerebral beta-amyloidosis in betaAPP-transgenic mice. Peptides. 23: 1241-7
Gyure KA, Durham R, Stewart WF, et al. (2001) Intraneuronal abeta-amyloid precedes development of amyloid plaques in Down syndrome. Archives of Pathology & Laboratory Medicine. 125: 489-92
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