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William R. Markesbery, MD, University of Kentucky

Pathology University of Kentucky, Lexington, KY 
neurology, oxidative stress, Alzheimer disease
"William Markesbery"

Cross-listing: Neurotree - Neuropathology Tree

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Iacono D, Zandi P, Gross M, et al. (2015) APOε2 and education in cognitively normal older subjects with high levels of AD pathology at autopsy: findings from the Nun Study. Oncotarget. 6: 14082-91
Gwon AR, Park JS, Arumugam TV, et al. (2012) Oxidative lipid modification of nicastrin enhances amyloidogenic γ-secretase activity in Alzheimer's disease. Aging Cell. 11: 559-68
Poon LW, Woodard JL, Stephen Miller L, et al. (2012) Understanding dementia prevalence among centenarians. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 67: 358-65
Ding Q, Zhu H, Zhang B, et al. (2012) Increased 5S rRNA oxidation in Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 29: 201-9
Bradley MA, Xiong-Fister S, Markesbery WR, et al. (2012) Elevated 4-hydroxyhexenal in Alzheimer's disease (AD) progression. Neurobiology of Aging. 33: 1034-44
Gleichmann M, Zhang Y, Wood WH, et al. (2012) Molecular changes in brain aging and Alzheimer's disease are mirrored in experimentally silenced cortical neuron networks. Neurobiology of Aging. 33: 205.e1-18
Robinson RA, Joshi G, Huang Q, et al. (2011) Proteomic analysis of brain proteins in APP/PS-1 human double mutant knock-in mice with increasing amyloid β-peptide deposition: insights into the effects of in vivo treatment with N-acetylcysteine as a potential therapeutic intervention in mild cognitive impairment and Alzheimer's disease. Proteomics. 11: 4243-56
Sultana R, Robinson RA, Di Domenico F, et al. (2011) Proteomic identification of specifically carbonylated brain proteins in APP(NLh)/APP(NLh) × PS-1(P264L)/PS-1(P264L) human double mutant knock-in mice model of Alzheimer disease as a function of age. Journal of Proteomics. 74: 2430-40
Aluise CD, Robinson RA, Cai J, et al. (2011) Redox proteomics analysis of brains from subjects with amnestic mild cognitive impairment compared to brains from subjects with preclinical Alzheimer's disease: insights into memory loss in MCI. Journal of Alzheimer's Disease : Jad. 23: 257-69
Kramer PL, Xu H, Woltjer RL, et al. (2011) Alzheimer disease pathology in cognitively healthy elderly: a genome-wide study. Neurobiology of Aging. 32: 2113-22
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