Nikolaos K. Robakis

Affiliations: 
Icahn School of Medicine at Mount Sinai, New York, NY, United States 
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"Nikolaos Robakis"
Cross-listing: Neurotree

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Publications

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Yoon Y, Voloudakis G, Doran N, et al. (2020) PS1 FAD mutants decrease ephrinB2-regulated angiogenic functions, ischemia-induced brain neovascularization and neuronal survival. Molecular Psychiatry
Zhao J, Xiao Y, Liu X, et al. (2020) Substrate interaction inhibits γ-secretase production of amyloid-β peptides. Chemical Communications (Cambridge, England)
Zhao J, Xiao Y, Liu X, et al. (2019) SUBSTRATE BINDING INHIBITS γ-SECRETASE CLEAVAGE OF AMYLOID PRECURSOR PROTEIN Alzheimers & Dementia. 15: 1595
Warren NA, Voloudakis G, Yoon Y, et al. (2018) The product of the γ-secretase processing of ephrinB2 regulates VE-cadherin complexes and angiogenesis. Cellular and Molecular Life Sciences : Cmls
Huang Q, Voloudakis G, Ren Y, et al. (2017) Presenilin1/γ-secretase protects neurons from glucose deprivation-induced death by regulating miR-212 and PEA15. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology
Fullard JF, Giambartolomei C, Hauberg ME, et al. (2017) Open chromatin profiling of human postmortem brain infers functional roles for non-coding schizophrenia loci. Human Molecular Genetics
Nikolakopoulou AM, Georgakopoulos A, Robakis NK. (2016) Presenilin 1 promotes trypsin-induced neuroprotection via the PAR2/ERK signaling pathway. Effects of presenilin 1 FAD mutations. Neurobiology of Aging. 42: 41-9
Zhu L, Zhong M, Elder GA, et al. (2015) Phospholipid dysregulation contributes to ApoE4-associated cognitive deficits in Alzheimer's disease pathogenesis. Proceedings of the National Academy of Sciences of the United States of America. 112: 11965-70
Bruban J, Voloudakis G, Huang Q, et al. (2015) Presenilin 1 is necessary for neuronal, but not glial, EGFR expression and neuroprotection via γ-secretase-independent transcriptional mechanisms. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology
Robakis NK, Georgakopoulos A. (2014) Allelic interference: a mechanism for trans-dominant transmission of loss of function in the neurodegeneration of familial Alzheimer's disease. Neuro-Degenerative Diseases. 13: 126-30
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