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Leonard Petrucelli, PhD

Affiliations: 
Neuroscience Research Mayo Clinic Jacksonville, Jacksonville, FL, United States 
Area:
http://www.biomedexperts.com/Profile.bme/1110907/Leonard_Petrucelli
Website:
http://mayoresearch.mayo.edu/mayo/research/staff/petrucelli_l.cfm
Google:
"Leonard Petrucelli"
Bio:

http://mayoresearch.mayo.edu/petrucelli_lab/

http://www.alzforum.org/com/res/detail.asp?id={6FC44417-BF30-4883-A2A1-95E498E8F852}

http://www.molecularneurodegeneration.com/edboard/start.asp?id=730361

Cross-listing: Neurotree

Children

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Joseph W Paul research assistant 2011-2013 Mayo Clinc (Cell Biology Tree)
Mercedes Prudencio post-doc Mayo Clinic Jacksonville (Neurotree)
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Publications

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Tacik P, DeTure MA, Yari C, et al. (2016) FTDP-17 with pick body-like inclusions associated with a novel tau mutation, p.E372G. Brain Pathology (Zurich, Switzerland)
Vanderweyde T, Apicco DJ, Youmans-Kidder K, et al. (2016) Interaction of tau with the RNA-binding Protein TIA1 Regulates tau Pathophysiology and Toxicity. Cell Reports
Todd TW, Petrucelli L. (2016) Insights into the pathogenic mechanisms of Chromosome 9 open reading frame 72 (C9orf72) repeat expansions. Journal of Neurochemistry
Zhang YJ, Gendron TF, Grima JC, et al. (2016) C9ORF72 poly(GA) aggregates sequester and impair HR23 and nucleocytoplasmic transport proteins. Nature Neuroscience
Josephs KA, Murray ME, Whitwell JL, et al. (2016) Updated TDP-43 in Alzheimer's disease staging scheme. Acta Neuropathologica
Esanov R, Belle KC, van Blitterswijk M, et al. (2015) C9orf72 promoter hypermethylation is reduced while hydroxymethylation is acquired during reprogramming of ALS patient cells. Experimental Neurology
Peters OM, Cabrera GT, Tran H, et al. (2015) Human C9ORF72 Hexanucleotide Expansion Reproduces RNA Foci and Dipeptide Repeat Proteins but Not Neurodegeneration in BAC Transgenic Mice. Neuron. 88: 902-909
O'Rourke JG, Bogdanik L, Muhammad AK, et al. (2015) C9orf72 BAC Transgenic Mice Display Typical Pathologic Features of ALS/FTD. Neuron. 88: 892-901
van Blitterswijk M, Gendron TF, Baker MC, et al. (2015) Novel clinical associations with specific C9ORF72 transcripts in patients with repeat expansions in C9ORF72. Acta Neuropathologica
Tran H, Almeida S, Moore J, et al. (2015) Differential Toxicity of Nuclear RNA Foci versus Dipeptide Repeat Proteins in a Drosophila Model of C9ORF72 FTD/ALS. Neuron. 87: 1207-14
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