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Andres M. Lebensohn, Ph.D. - Publications

Affiliations: 
Harvard University, Cambridge, MA, United States 
Area:
Cell Cycle, Cytoskeleton, Systems Biology
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20 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 McKenna JK, Wu Y, Sonkusre P, Lebensohn AM. The ubiquitin ligase HUWE1 enhances WNT signaling by antagonizing destruction complex-mediated β-catenin degradation and through a mechanism independent of β-catenin stability. Biorxiv : the Preprint Server For Biology. PMID 38410441 DOI: 10.1101/2024.02.02.578552  0.464
2023 Khandwala CB, Sarkar P, Schmidt HB, Ma M, Kinnebrew M, Pusapati GV, Patel BB, Tillo D, Lebensohn AM, Rohatgi R. Direct ionic stress sensing and mitigation by the transcription factor NFAT5. Biorxiv : the Preprint Server For Biology. PMID 37886503 DOI: 10.1101/2023.09.23.559074  0.525
2023 Ng VH, Spencer Z, Neitzel LR, Nayak A, Loberg MA, Shen C, Kassel SN, Kroh HK, An Z, Anthony CC, Bryant JM, Lawson A, Goldsmith L, Benchabane H, Hansen AG, ... ... Lebensohn AM, et al. The USP46 complex deubiquitylates LRP6 to promote Wnt/β-catenin signaling. Nature Communications. 14: 6173. PMID 37798301 DOI: 10.1038/s41467-023-41836-z  0.645
2023 Spencer ZT, Ng VH, Benchabane H, Siddiqui GS, Duwadi D, Maines B, Bryant JM, Schwarzkopf A, Yuan K, Kassel SN, Mishra A, Pimentel A, Lebensohn AM, Rohatgi R, Gerber SA, et al. The USP46 deubiquitylase complex increases Wingless/Wnt signaling strength by stabilizing Arrow/LRP6. Nature Communications. 14: 6174. PMID 37798281 DOI: 10.1038/s41467-023-41843-0  0.641
2022 Lebensohn AM, Bazan JF, Rohatgi R. Receptor control by membrane-tethered ubiquitin ligases in development and tissue homeostasis. Current Topics in Developmental Biology. 150: 25-89. PMID 35817504 DOI: 10.1016/bs.ctdb.2022.03.003  0.586
2020 Dubey R, van Kerkhof P, Jordens I, Malinauskas T, Pusapati GV, McKenna JK, Li D, Carette JE, Ho M, Siebold C, Maurice M, Lebensohn AM, Rohatgi R. R-spondins engage heparan sulfate proteoglycans to potentiate WNT signaling. Elife. 9. PMID 32432544 DOI: 10.7554/Elife.54469  0.665
2020 Dubey R, Kerkhof Pv, Jordens I, Malinauskas T, Pusapati GV, McKenna JK, Li D, Carette JE, Ho M, Siebold C, Maurice M, Lebensohn AM, Rohatgi R. Author response: R-spondins engage heparan sulfate proteoglycans to potentiate WNT signaling Elife. DOI: 10.7554/Elife.54469.Sa2  0.607
2019 Patel BB, Lebensohn AM, Pusapati GV, Carette JE, Salzman J, Rohatgi R. Discovery of gene regulatory elements through a new bioinformatics analysis of haploid genetic screens. Plos One. 14: e0198463. PMID 30695034 DOI: 10.1371/Journal.Pone.0198463  0.569
2019 Lebensohn AM, Rohatgi R. Abstract 3445: Mechanism, physiological and therapeutic implications of LGR-independent potentiation of WNT signaling by R-spondins Cancer Research. DOI: 10.1158/1538-7445.Sabcs18-3445  0.622
2018 Lebensohn AM, Rohatgi R. R-spondins can potentiate WNT signaling without LGRs. Elife. 7. PMID 29405118 DOI: 10.7554/Elife.33126  0.674
2016 Lebensohn AM, Dubey R, Neitzel LR, Tacchelly-Benites O, Yang E, Marceau CD, Davis EM, Patel BB, Bahrami-Nejad Z, Travaglini KJ, Ahmed Y, Lee E, Carette JE, Rohatgi R. Comparative genetic screens in human cells reveal new regulatory mechanisms in WNT signaling. Elife. 5. PMID 27996937 DOI: 10.7554/Elife.21459  0.691
2016 Dubey R, Lebensohn A, Bahrami-Nejad Z, Marceau C, Champion M, Gevaert O, Sikic BI, Carette JE, Rohatgi R. Chromatin-remodeling complex SWI/SNF controls multidrug resistance by transcriptionally regulating the drug efflux pump ABCB1. Cancer Research. PMID 27503929 DOI: 10.1158/0008-5472.Can-16-0716  0.548
2016 Lebensohn AM, Dubey R, Neitzel LR, Tacchelly-Benites O, Yang E, Marceau CD, Davis EM, Patel BB, Bahrami-Nejad Z, Travaglini KJ, Ahmed Y, Lee E, Carette JE, Rohatgi R. Author response: Comparative genetic screens in human cells reveal new regulatory mechanisms in WNT signaling Elife. DOI: 10.7554/Elife.21459.025  0.633
2016 Lebensohn AM, Dubey R, Neitzel LR, Tacchelly O, Marceau CD, Bahrami Z, Hansen AG, Ahmed Y, Lee E, Carette J, Rohatgi R. Abstract PR05: Systematic forward genetic screens in haploid human cells reveal new players and regulatory mechanisms in Wnt signaling Molecular Cancer Research. 14. DOI: 10.1158/1557-3125.Devbiolca15-Pr05  0.689
2013 Lebensohn A, Hughes C, Marceau C, Rohatgi R, Carette J. Abstract PR03: Genome-wide screens for Wnt signaling in human haploid cells Molecular Cancer Therapeutics. 12. DOI: 10.1158/1535-7163.Pms-Pr03  0.66
2009 Lebensohn AM, Kirschner MW. Activation of the WAVE complex by coincident signals controls actin assembly. Molecular Cell. 36: 512-24. PMID 19917258 DOI: 10.1016/J.Molcel.2009.10.024  0.565
2006 Peterson JR, Lebensohn AM, Pelish HE, Kirschner MW. Biochemical suppression of small-molecule inhibitors: a strategy to identify inhibitor targets and signaling pathway components. Chemistry & Biology. 13: 443-52. PMID 16632257 DOI: 10.1016/J.Chembiol.2006.02.009  0.57
2006 Ho HY, Rohatgi R, Lebensohn AM, Kirschner MW. In vitro reconstitution of cdc42-mediated actin assembly using purified components. Methods in Enzymology. 406: 174-90. PMID 16472658 DOI: 10.1016/S0076-6879(06)06014-9  0.662
2006 Lebensohn AM, Ma L, Ho HY, Kirschner MW. Cdc42 and PI(4,5)P2-induced actin assembly in Xenopus egg extracts. Methods in Enzymology. 406: 156-73. PMID 16472657 DOI: 10.1016/S0076-6879(06)06013-7  0.611
2004 Ho HY, Rohatgi R, Lebensohn AM, Le Ma, Li J, Gygi SP, Kirschner MW. Toca-1 mediates Cdc42-dependent actin nucleation by activating the N-WASP-WIP complex. Cell. 118: 203-16. PMID 15260990 DOI: 10.1016/J.Cell.2004.06.027  0.661
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