Zhongfa Liu, Ph.D. - Publications

Affiliations: 
2003 Case Western Reserve University, Cleveland Heights, OH, United States 

55 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Yuan S, Lei F, Liu Z, Tong Q, Si T, Xu RX. Coaxial Electrospray of Curcumin-Loaded Microparticles for Sustained Drug Release. Plos One. 10: e0132609. PMID 26208167 DOI: 10.1371/journal.pone.0132609  0.96
2015 Han BB, Li S, Tong M, Holpuch AS, Spinney R, Wang D, Border MB, Liu Z, Sarode S, Pei P, Schwendeman SP, Mallery SR. Fenretinide Perturbs Focal Adhesion Kinase in Premalignant and Malignant Human Oral Keratinocytes. Fenretinide's Chemopreventive Mechanisms Include ECM Interactions. Cancer Prevention Research (Philadelphia, Pa.). 8: 419-30. PMID 25712051 DOI: 10.1158/1940-6207.CAPR-14-0418  0.96
2014 Young NA, Bruss MS, Gardner M, Willis WL, Mo X, Valiente GR, Cao Y, Liu Z, Jarjour WN, Wu LC. Oral administration of nano-emulsion curcumin in mice suppresses inflammatory-induced NFκB signaling and macrophage migration. Plos One. 9: e111559. PMID 25369140 DOI: 10.1371/journal.pone.0111559  0.96
2014 Cao Y, Xu RX, Liu Z. A high-throughput quantification method of curcuminoids and curcumin metabolites in human plasma via high-performance liquid chromatography/tandem mass spectrometry. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. 949: 70-8. PMID 24480327 DOI: 10.1016/j.jchromb.2013.12.039  0.96
2014 Klisovic RB, Blum W, Liu Z, Xie Z, Kefauver C, Huynh L, Zwiebel JA, Devine SM, Byrd JC, Grever MR, Chan KK, Marcucci G. Phase I study of GTI-2040, a ribonucleotide reductase antisense, with high dose cytarabine in patients with relapsed/refractory acute myeloid leukemia. Leukemia & Lymphoma. 55: 1332-6. PMID 24015841 DOI: 10.3109/10428194.2013.838764  0.96
2013 Christoforidis JB, Xie Z, Jiang A, Wang J, Pratt C, Gemensky-Metzler A, Abdel-Rasoul M, Roy S, Liu Z. Serum levels of intravitreal bevacizumab after vitrectomy, lensectomy and non-surgical controls. Current Eye Research. 38: 761-6. PMID 23548066 DOI: 10.3109/02713683.2013.763988  0.96
2013 Liu Z, Ren C, Jones W, Chen P, Seminara SB, Chan YM, Smith NF, Covey JM, Wang J, Chan KK. LC-MS/MS quantification of a neuropeptide fragment kisspeptin-10 (NSC 741805) and characterization of its decomposition product and pharmacokinetics in rats. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. 926: 1-8. PMID 23524040 DOI: 10.1016/j.jchromb.2013.02.027  0.96
2013 Fan-Havard P, Liu Z, Chou M, Ling Y, Barrail-Tran A, Haas DW, Taburet AM. Pharmacokinetics of phase I nevirapine metabolites following a single dose and at steady state. Antimicrobial Agents and Chemotherapy. 57: 2154-60. PMID 23459477 DOI: 10.1128/AAC.02294-12  0.96
2013 Yu J, Peng Y, Wu LC, Xie Z, Deng Y, Hughes T, He S, Mo X, Chiu M, Wang QE, He X, Liu S, Grever MR, Chan KK, Liu Z. Curcumin down-regulates DNA methyltransferase 1 and plays an anti-leukemic role in acute myeloid leukemia. Plos One. 8: e55934. PMID 23457487 DOI: 10.1371/journal.pone.0055934  0.96
2013 Aarnes TK, Fry PR, Hubbell JAE, Bednarski RM, Lerche P, Chen W, Bei D, Liu Z, Lakritz J. Pharmacokinetics and pharmacodynamics of midazolam after intravenous and intramuscular administration in alpacas American Journal of Veterinary Research. 74: 294-299. PMID 23363357 DOI: 10.2460/ajvr.74.2.294  0.96
2013 Wang H, Chen P, Wang J, Santhanam R, Aimiuwu J, Saradhi UV, Liu Z, Schwind S, Mims A, Byrd JC, Grever MR, Villalona-Calero MA, Klisovic R, Walker A, Garzon R, et al. In vivo quantification of active decitabine-triphosphate metabolite: a novel pharmacoanalytical endpoint for optimization of hypomethylating therapy in acute myeloid leukemia. The Aaps Journal. 15: 242-9. PMID 23180159 DOI: 10.1208/s12248-012-9427-5  0.96
2013 Mortazavi A, Ling Y, Martin LK, Wei L, Phelps MA, Liu Z, Harper EJ, Ivy SP, Wu X, Zhou BS, Liu X, Deam D, Monk JP, Hicks WJ, Yen Y, et al. A phase I study of prolonged infusion of triapine in combination with fixed dose rate gemcitabine in patients with advanced solid tumors. Investigational New Drugs. 31: 685-95. PMID 22847785 DOI: 10.1007/s10637-012-9863-1  0.96
2012 Du L, Xie Z, Wu LC, Chiu M, Lin J, Chan KK, Liu S, Liu Z. Reactivation of RASSF1A in breast cancer cells by curcumin. Nutrition and Cancer. 64: 1228-35. PMID 23145775 DOI: 10.1080/01635581.2012.717682  0.96
2012 Chen W, Wang D, Wang LS, Bei D, Wang J, See WA, Mallery SR, Stoner GD, Liu Z. Pharmacokinetics of protocatechuic acid in mouse and its quantification in human plasma using LC-tandem mass spectrometry. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. 908: 39-44. PMID 23122399 DOI: 10.1016/j.jchromb.2012.09.032  0.96
2012 Lu K, Chakroborty D, Sarkar C, Lu T, Xie Z, Liu Z, Basu S. Triphala and its active constituent chebulinic acid are natural inhibitors of vascular endothelial growth factor-a mediated angiogenesis. Plos One. 7: e43934. PMID 22937129 DOI: 10.1371/journal.pone.0043934  0.96
2012 Chen W, Fan-Havard P, Yee LD, Cao Y, Stoner GD, Chan KK, Liu Z. A liquid chromatography-tandem mass spectrometric method for quantification of curcumin-O-glucuronide and curcumin in human plasma. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. 900: 89-93. PMID 22682887 DOI: 10.1016/j.jchromb.2012.05.026  0.96
2012 Wang H, Chiu M, Xie Z, Chiu M, Liu Z, Chen P, Liu S, Byrd JC, Muthusamy N, Garzon R, Croce CM, Marcucci G, Chan KK. Synthetic microRNA cassette dosing: pharmacokinetics, tissue distribution and bioactivity. Molecular Pharmaceutics. 9: 1638-44. PMID 22574727 DOI: 10.1021/mp2006483  0.96
2012 Holpuch AS, Phelps MP, Desai KG, Chen W, Koutras GM, Han BB, Warner BM, Pei P, Seghi GA, Tong M, Border MB, Fields HW, Stoner GD, Larsen PE, Liu Z, et al. Evaluation of a mucoadhesive fenretinide patch for local intraoral delivery: a strategy to reintroduce fenretinide for oral cancer chemoprevention. Carcinogenesis. 33: 1098-105. PMID 22427354 DOI: 10.1093/carcin/bgs122  0.96
2011 Chakroborty D, Sarkar C, Yu H, Wang J, Liu Z, Dasgupta PS, Basu S. Dopamine stabilizes tumor blood vessels by up-regulating angiopoietin 1 expression in pericytes and Kruppel-like factor-2 expression in tumor endothelial cells. Proceedings of the National Academy of Sciences of the United States of America. 108: 20730-5. PMID 22143796 DOI: 10.1073/pnas.1108696108  0.96
2011 Hofmeister CC, Yang X, Pichiorri F, Chen P, Rozewski DM, Johnson AJ, Lee S, Liu Z, Garr CL, Hade EM, Ji J, Schaaf LJ, Benson DM, Kraut EH, Hicks WJ, et al. Phase I trial of lenalidomide and CCI-779 in patients with relapsed multiple myeloma: evidence for lenalidomide-CCI-779 interaction via P-glycoprotein. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 29: 3427-34. PMID 21825263 DOI: 10.1200/JCO.2010.32.4962  0.96
2011 Mallery SR, Budendorf DE, Larsen MP, Pei P, Tong M, Holpuch AS, Larsen PE, Stoner GD, Fields HW, Chan KK, Ling Y, Liu Z. Effects of human oral mucosal tissue, saliva, and oral microflora on intraoral metabolism and bioactivation of black raspberry anthocyanins. Cancer Prevention Research (Philadelphia, Pa.). 4: 1209-21. PMID 21558412 DOI: 10.1158/1940-6207.CAPR-11-0040  0.96
2011 Saradhi UV, Gupta SV, Chiu M, Wang J, Ling Y, Liu Z, Newman DJ, Covey JM, Kinghorn AD, Marcucci G, Lucas DM, Grever MR, Phelps MA, Chan KK. Characterization of silvestrol pharmacokinetics in mice using liquid chromatography-tandem mass spectrometry. The Aaps Journal. 13: 347-56. PMID 21499689 DOI: 10.1208/s12248-011-9273-x  0.96
2010 Vijaya Saradhi UV, Ling Y, Wang J, Chiu M, Schwartz EB, Fuchs JR, Chan KK, Liu Z. A liquid chromatography-tandem mass spectrometric method for quantification of curcuminoids in cell medium and mouse plasma. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. 878: 3045-51. PMID 20934924 DOI: 10.1016/j.jchromb.2010.08.039  0.96
2010 Chan KK, Liu Z, Xie Z, Chiu M, Wang H, Chen P, Dunkerson S, Chiu M, Liu S, Triantafillou G, Garzon R, Croce CM, Byrd JC, Muthusamy N, Marcucci G. A novel ultrasensitive hybridization-based ELISA method for 2-methoxyphosphorothiolate microRNAs and its in vitro and in vivo application. The Aaps Journal. 12: 556-68. PMID 20625866 DOI: 10.1208/s12248-010-9214-0  0.96
2010 Blum KA, Liu Z, Lucas DM, Chen P, Xie Z, Baiocchi R, Benson DM, Devine SM, Jones J, Andritsos L, Flynn J, Plass C, Marcucci G, Chan KK, Grever MR, et al. Phase I trial of low dose decitabine targeting DNA hypermethylation in patients with chronic lymphocytic leukaemia and non-Hodgkin lymphoma: dose-limiting myelosuppression without evidence of DNA hypomethylation. British Journal of Haematology. 150: 189-95. PMID 20456354 DOI: 10.1111/j.1365-2141.2010.08213.x  0.96
2010 Ren C, Fan-Havard P, Schlabritz-Loutsevitch N, Ling Y, Chan KK, Liu Z. A sensitive and specific liquid chromatography/tandem mass spectrometry method for quantification of nevirapine and its five metabolites and their pharmacokinetics in baboons. Biomedical Chromatography : Bmc. 24: 717-26. PMID 19882749 DOI: 10.1002/bmc.1353  0.96
2009 Ling Y, Ren C, Mallery SR, Ugalde CM, Pei P, Saradhi UV, Stoner GD, Chan KK, Liu Z. A rapid and sensitive LC-MS/MS method for quantification of four anthocyanins and its application in a clinical pharmacology study of a bioadhesive black raspberry gel. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. 877: 4027-34. PMID 19896910 DOI: 10.1016/j.jchromb.2009.10.026  0.96
2009 Liu Z, Wu J, Xie Z, Liu S, Fan-Havard P, Huang TH, Plass C, Marcucci G, Chan KK. Quantification of regional DNA methylation by liquid chromatography/tandem mass spectrometry. Analytical Biochemistry. 391: 106-13. PMID 19442645 DOI: 10.1016/j.ab.2009.05.012  0.96
2009 Yu J, Ershler M, Yu L, Wei M, Hackanson B, Yokohama A, Mitsui T, Liu C, Mao H, Liu S, Liu Z, Trotta R, Liu CG, Liu X, Huang K, et al. TSC-22 contributes to hematopoietic precursor cell proliferation and repopulation and is epigenetically silenced in large granular lymphocyte leukemia. Blood. 113: 5558-67. PMID 19329776 DOI: 10.1182/blood-2009-02-205732  0.96
2009 Chen P, Liu Z, Liu S, Xie Z, Aimiuwu J, Pang J, Klisovic R, Blum W, Grever MR, Marcucci G, Chan KK. A LC-MS/MS method for the analysis of intracellular nucleoside triphosphate levels. Pharmaceutical Research. 26: 1504-15. PMID 19291372 DOI: 10.1007/s11095-009-9863-9  0.96
2009 Garzon R, Liu S, Fabbri M, Liu Z, Heaphy CE, Callegari E, Schwind S, Pang J, Yu J, Muthusamy N, Havelange V, Volinia S, Blum W, Rush LJ, Perrotti D, et al. MicroRNA-29b induces global DNA hypomethylation and tumor suppressor gene reexpression in acute myeloid leukemia by targeting directly DNMT3A and 3B and indirectly DNMT1. Blood. 113: 6411-8. PMID 19211935 DOI: 10.1182/blood-2008-07-170589  0.96
2009 Liu Z, Liu S, Xie Z, Pavlovicz RE, Wu J, Chen P, Aimiuwu J, Pang J, Bhasin D, Neviani P, Fuchs JR, Plass C, Li PK, Li C, Huang TH, et al. Modulation of DNA methylation by a sesquiterpene lactone parthenolide. The Journal of Pharmacology and Experimental Therapeutics. 329: 505-14. PMID 19201992 DOI: 10.1124/jpet.108.147934  0.96
2009 Ugalde CM, Liu Z, Ren C, Chan KK, Rodrigo KA, Ling Y, Larsen PE, Chacon GE, Stoner GD, Mumper RJ, Fields HW, Mallery SR. Distribution of anthocyanins delivered from a bioadhesive black raspberry gel following topical intraoral application in normal healthy volunteers. Pharmaceutical Research. 26: 977-86. PMID 19137418 DOI: 10.1007/s11095-008-9806-x  0.96
2009 Liu Z, Xie Z, Jones W, Pavlovicz RE, Liu S, Yu J, Li PK, Lin J, Fuchs JR, Marcucci G, Li C, Chan KK. Curcumin is a potent DNA hypomethylation agent. Bioorganic & Medicinal Chemistry Letters. 19: 706-9. PMID 19112019 DOI: 10.1016/j.bmcl.2008.12.041  0.96
2008 Liu Z, Zhang Y, Hua YF, Covey JM, Benbrook DM, Chan KK. Metabolism of a sulfur-containing heteroarotionoid antitumor agent, SHetA2, using liquid chromatography/tandem mass spectrometry. Rapid Communications in Mass Spectrometry : Rcm. 22: 3371-81. PMID 18837006 DOI: 10.1002/rcm.3744  0.96
2008 Wei X, Dai G, Liu Z, Cheng H, Xie Z, Klisovic R, Marcucci G, Chan KK. Enzyme kinetics of GTI-2040, a phosphorothioate oligonucleotide targeting ribonucleotide reductase. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 36: 2227-33. PMID 18653746 DOI: 10.1124/dmd.108.021295  0.96
2008 Klisovic RB, Blum W, Wei X, Liu S, Liu Z, Xie Z, Vukosavljevic T, Kefauver C, Huynh L, Pang J, Zwiebel JA, Devine S, Byrd JC, Grever MR, Chan K, et al. Phase I study of GTI-2040, an antisense to ribonucleotide reductase, in combination with high-dose cytarabine in patients with acute myeloid leukemia. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 14: 3889-95. PMID 18559610 DOI: 10.1158/1078-0432.CCR-08-0109  0.96
2008 Liu S, Liu Z, Xie Z, Pang J, Yu J, Lehmann E, Huynh L, Vukosavljevic T, Takeki M, Klisovic RB, Baiocchi RA, Blum W, Porcu P, Garzon R, Byrd JC, et al. Bortezomib induces DNA hypomethylation and silenced gene transcription by interfering with Sp1/NF-kappaB-dependent DNA methyltransferase activity in acute myeloid leukemia. Blood. 111: 2364-73. PMID 18083845 DOI: 10.1182/blood-2007-08-110171  0.96
2007 Fabbri M, Garzon R, Cimmino A, Liu Z, Zanesi N, Callegari E, Liu S, Alder H, Costinean S, Fernandez-Cymering C, Volinia S, Guler G, Morrison CD, Chan KK, Marcucci G, et al. MicroRNA-29 family reverts aberrant methylation in lung cancer by targeting DNA methyltransferases 3A and 3B. Proceedings of the National Academy of Sciences of the United States of America. 104: 15805-10. PMID 17890317 DOI: 10.1073/pnas.0707628104  0.96
2007 Blum W, Klisovic RB, Hackanson B, Liu Z, Liu S, Devine H, Vukosavljevic T, Huynh L, Lozanski G, Kefauver C, Plass C, Devine SM, Heerema NA, Murgo A, Chan KK, et al. Phase I study of decitabine alone or in combination with valproic acid in acute myeloid leukemia. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 25: 3884-91. PMID 17679729 DOI: 10.1200/JCO.2006.09.4169  0.96
2007 Liu Z, Fan-Havard P, Xie Z, Ren C, Chan KK. A liquid chromatography/atmospheric pressure ionization tandem mass spectrometry quantitation method for nevirapine and its two oxidative metabolites, 2-hydroxynevirapine and nevirapine 4-carboxylic acid, and pharmacokinetics in baboons. Rapid Communications in Mass Spectrometry : Rcm. 21: 2734-42. PMID 17654464 DOI: 10.1002/rcm.3136  0.96
2007 Liu S, Klisovic RB, Vukosavljevic T, Yu J, Paschka P, Huynh L, Pang J, Neviani P, Liu Z, Blum W, Chan KK, Perrotti D, Marcucci G. Targeting AML1/ETO-histone deacetylase repressor complex: a novel mechanism for valproic acid-mediated gene expression and cellular differentiation in AML1/ETO-positive acute myeloid leukemia cells. The Journal of Pharmacology and Experimental Therapeutics. 321: 953-60. PMID 17389244 DOI: 10.1124/jpet.106.118406  0.96
2007 Liu Z, Liu S, Xie Z, Blum W, Perrotti D, Paschka P, Klisovic R, Byrd J, Chan KK, Marcucci G. Characterization of in vitro and in vivo hypomethylating effects of decitabine in acute myeloid leukemia by a rapid, specific and sensitive LC-MS/MS method. Nucleic Acids Research. 35: e31. PMID 17264127 DOI: 10.1093/nar/gkl1156  0.96
2007 Cheng H, Liu Z, Blum W, Byrd JC, Klisovic R, Grever MR, Marcucci G, Chan KK. Quantification of valproic acid and its metabolite 2-propyl-4-pentenoic acid in human plasma using HPLC-MS/MS. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. 850: 206-12. PMID 17147984 DOI: 10.1016/j.jchromb.2006.11.027  0.96
2006 Wei X, Dai G, Liu Z, Cheng H, Xie Z, Marcucci G, Chan KK. Metabolism of GTI-2040, a phosphorothioate oligonucleotide antisense, using ion-pair reversed phase high performance liquid chromatography (HPLC) coupled with electrospray ion-trap mass spectrometry. The Aaps Journal. 8: E743-55. PMID 17285740  0.96
2006 Wei X, Dai G, Marcucci G, Liu Z, Hoyt D, Blum W, Chan KK. A specific picomolar hybridization-based ELISA assay for the determination of phosphorothioate oligonucleotides in plasma and cellular matrices. Pharmaceutical Research. 23: 1251-64. PMID 16718617 DOI: 10.1007/s11095-006-0082-3  0.96
2006 Zhang Y, Hua Y, Benbrook DM, Covey JM, Dai G, Liu Z, Chan KK. High performance liquid chromatographic analysis and preclinical pharmacokinetics of the heteroarotinoid antitumor agent, SHetA2. Cancer Chemotherapy and Pharmacology. 58: 561-9. PMID 16534614 DOI: 10.1007/s00280-006-0211-z  0.96
2006 Liu Z, Marcucci G, Byrd JC, Grever M, Xiao J, Chan KK. Characterization of decomposition products and preclinical and low dose clinical pharmacokinetics of decitabine (5-aza-2'-deoxycytidine) by a new liquid chromatography/tandem mass spectrometry quantification method. Rapid Communications in Mass Spectrometry : Rcm. 20: 1117-26. PMID 16523529 DOI: 10.1002/rcm.2423  0.96
2005 Dai G, Wei X, Liu Z, Liu S, Marcucci G, Chan KK. Characterization and quantification of Bcl-2 antisense G3139 and metabolites in plasma and urine by ion-pair reversed phase HPLC coupled with electrospray ion-trap mass spectrometry. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. 825: 201-13. PMID 16111926 DOI: 10.1016/j.jchromb.2005.05.049  0.96
2005 Liu Z, Chan KK, Wang JJ. Tandem mass spectrometric analysis of cyclophosphamide, ifosfamide and their metabolites. Rapid Communications in Mass Spectrometry : Rcm. 19: 2581-90. PMID 16106352 DOI: 10.1002/rcm.2099  0.96
2005 Liu Z, Floss HG, Cassady JM, Chan KK. Metabolism studies of the anti-tumor agent maytansine and its analog ansamitocin P-3 using liquid chromatography/tandem mass spectrometry. Journal of Mass Spectrometry : Jms. 40: 389-99. PMID 15674857 DOI: 10.1002/jms.800  0.96
2004 Liu Z, Floss HG, Cassady JM, Xiao J, Chan KK. An API LC/MS/MS quantitation method for ansamitocin P-3 (AP3) and its preclinical pharmacokinetics. Journal of Pharmaceutical and Biomedical Analysis. 36: 815-21. PMID 15533675 DOI: 10.1016/j.jpba.2004.07.045  0.96
2004 Liu Z, Minkler PE, Lin D, Sayre LM. Derivatization of amino acids with N,N-dimethyl-2,4-dinitro-5-fluorobenzylamine for liquid chromatography/electrospray ionization mass spectrometry. Rapid Communications in Mass Spectrometry : Rcm. 18: 1059-65. PMID 15150828 DOI: 10.1002/rcm.1443  0.96
2003 Liu Z, Minkler PE, Sayre LM. Mass spectroscopic characterization of protein modification by 4-hydroxy-2-(E)-nonenal and 4-oxo-2-(E)-nonenal. Chemical Research in Toxicology. 16: 901-11. PMID 12870893 DOI: 10.1021/tx0300030  0.96
2003 Liu Z, Sayre LM. Model studies on the modification of proteins by lipoxidation-derived 2-hydroxyaldehydes. Chemical Research in Toxicology. 16: 232-41. PMID 12588195 DOI: 10.1021/tx020095d  0.96
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