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Kenneth R. Crawford, Ph.D. - Publications

Affiliations: 
2002 Johns Hopkins University, Baltimore, MD 
Area:
Medicinal, Organic and Organometallic Chemistry
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7 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2006 Lin X, Murray JM, Rico AC, Wang MX, Chu DT, Zhou Y, Del Rosario M, Kaufman S, Ma S, Fang E, Crawford K, Jefferson AB. Discovery of 2-pyrimidyl-5-amidothiophenes as potent inhibitors for AKT: synthesis and SAR studies. Bioorganic & Medicinal Chemistry Letters. 16: 4163-8. PMID 16765046 DOI: 10.1016/j.bmcl.2006.05.092  0.316
2004 Posner GH, Crawford KR, Yang HW, Kahraman M, Jeon HB, Li H, Lee JK, Suh BC, Hatcher MA, Labonte T, Usera A, Dolan PM, Kensler TW, Peleg S, Jones G, et al. Potent, low-calcemic, selective inhibitors of CYP24 hydroxylase: 24-Sulfone analogs of the hormone 1α,25-dihydroxyvitamin D3 Journal of Steroid Biochemistry and Molecular Biology. 89: 5-12. PMID 15225738 DOI: 10.1016/J.Jsbmb.2004.03.044  0.44
2002 Posner GH, Woodard BT, Crawford KR, Peleg S, Brown AJ, Dolan P, Kensler TW. 2,2-Disubstituted analogues of the natural hormone 1 alpha,25-dihydroxyvitamin D(3): chemistry and biology. Bioorganic & Medicinal Chemistry. 10: 2353-65. PMID 11983533 DOI: 10.1016/S0968-0896(02)00058-5  0.595
2001 Posner GH, Crawford KR, Peleg S, Welsh JE, Romu S, Gewirtz DA, Gupta MS, Dolan P, Kensler TW. A non-calcemic sulfone version of the vitamin D(3) analogue seocalcitol (EB 1089): chemical synthesis, biological evaluation and potency enhancement of the anticancer drug adriamycin. Bioorganic & Medicinal Chemistry. 9: 2365-71. PMID 11553477 DOI: 10.1016/S0968-0896(01)00159-6  0.672
2000 Posner GH, Crawford K, Siu-Caldera ML, Reddy GS, Sarabia SF, Feldman D, van Etten E, Mathieu C, Gennaro L, Vouros P, Peleg S, Dolan PM, Kensler TW. Conceptually new 20-epi-22-oxa sulfone analogues of the hormone 1alpha,25-dihydroxyvitamin D(3): synthesis and biological evaluation. Journal of Medicinal Chemistry. 43: 3581-6. PMID 11000014 DOI: 10.1021/Jm000215J  0.72
1999 Posner GH, Wang Q, Han G, Lee JK, Crawford K, Zand S, Brem H, Peleg S, Dolan P, Kensler TW. Conceptually new sulfone analogues of the hormone 1alpha, 25-dihydroxyvitamin D(3): synthesis and preliminary biological evaluation. Journal of Medicinal Chemistry. 42: 3425-35. PMID 10479276 DOI: 10.1021/Jm990267C  0.64
1998 Crawford KR, Posner GH. A highly stereoselective pentannulation of prochiral cyclic enones using a chiral 1,3-dipole equivalent Chemtracts. 11: 561-564.  0.382
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