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Mark Tuszynski - Publications

Affiliations: 
University of California, San Diego, La Jolla, CA 
Area:
plasticity, Alzheimer's, regeneration
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195 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Huie JR, Torres-Espin A, Sacramento J, Keller AV, Joiner WM, North R, Reinkensmeyer DJ, Rosenzweig ES, Koffler J, Tuszynski MH, Sparrey CJ, Nielson JL, Beattie MS, Bresnahan JC, Grethe JS, et al. An infrastructure for qualified data sharing and team science in late-stage translational spinal cord injury research. Experimental Neurology. 383: 114995. PMID 39393672 DOI: 10.1016/j.expneurol.2024.114995  0.716
2024 Lu P, Graham L, Tran AN, Villarta A, Koffler J, Tuszynski MH. A Facilitatory role of astrocytes in axonal regeneration after acute and chronic spinal cord injury. Experimental Neurology. 114889. PMID 39019303 DOI: 10.1016/j.expneurol.2024.114889  0.461
2024 Sahoo PK, Hanovice N, Ward P, Agrawal M, Smith TP, SiMa H, Dulin JN, Vaughn LS, Tuszynski M, Welshhans K, Benowitz L, English A, Houle JD, Twiss JL. Disruption of Core Stress Granule Protein Aggregates Promotes CNS Axon Regeneration. Biorxiv : the Preprint Server For Biology. PMID 38895344 DOI: 10.1101/2024.06.07.597743  0.781
2024 Takashima Y, Biane JS, Tuszynski MH. Selective plasticity of layer 2/3 inputs onto distal forelimb controlling layer 5 corticospinal neurons with skilled grasp motor training. Cell Reports. 43: 113986. PMID 38598336 DOI: 10.1016/j.celrep.2024.113986  0.77
2023 Wai G, Zdunowski S, Zhong H, Nielson JL, Ferguson AR, Strand SC, Moseanko R, Hawbecker S, Nout-Lomas YS, Rosenzweig ES, Beattie MS, Bresnahan JC, Tuszynski MH, Roy RR, Edgerton VR. Emergence of functionally aberrant and subsequent reduction of neuromuscular connectivity and improved motor performance after cervical spinal cord injury in Rhesus. Frontiers in Rehabilitation Sciences. 4: 1205456. PMID 37378049 DOI: 10.3389/fresc.2023.1205456  0.744
2023 Zheng B, Tuszynski MH. Regulation of axonal regeneration after mammalian spinal cord injury. Nature Reviews. Molecular Cell Biology. PMID 36604586 DOI: 10.1038/s41580-022-00562-y  0.525
2022 Li Y, Tran A, Graham L, Brock J, Tuszynski MH, Lu P. BDNF guides neural stem cell-derived axons to ventral interneurons and motor neurons after spinal cord injury. Experimental Neurology. 114259. PMID 36309123 DOI: 10.1016/j.expneurol.2022.114259  0.649
2022 Lu P, Freria CM, Graham L, Tran AN, Villarta A, Yassin D, Huie JR, Ferguson AR, Tuszynski MH. Rehabilitation combined with neural progenitor cell grafts enables functional recovery in chronic spinal cord injury. Jci Insight. 7. PMID 35993363 DOI: 10.1172/jci.insight.158000  0.372
2022 Sinopoulou E, Rosenzweig ES, Conner JM, Gibbs D, Weinholtz CA, Weber JL, Brock JH, Nout-Lomas YS, Ovruchesky E, Takashima Y, Biane JS, Kumamaru H, Havton LA, Beattie MS, Bresnahan JC, ... Tuszynski MH, et al. Rhesus macaque versus rat divergence in the corticospinal projectome. Neuron. PMID 35917818 DOI: 10.1016/j.neuron.2022.07.002  0.821
2022 van Niekerk EA, Kawaguchi R, Marques de Freria C, Groeniger K, Marchetto MC, Dupraz S, Bradke F, Geschwind DH, Gage FH, Tuszynski MH. Methods for culturing adult CNS neurons reveal a CNS conditioning effect. Cell Reports Methods. 2: 100255. PMID 35880023 DOI: 10.1016/j.crmeth.2022.100255  0.475
2021 North R, Wurr R, Macon R, Mannion C, Hyde J, Torres-Espin A, Rosenzweig ES, Ferguson AR, Tuszynski MH, Beattie MS, Bresnahan JC, Joiner WM. Quantifying the kinematic features of dexterous finger movements in nonhuman primates with markerless tracking. Annual International Conference of the Ieee Engineering in Medicine and Biology Society. Ieee Engineering in Medicine and Biology Society. Annual International Conference. 2021: 6110-6115. PMID 34892511 DOI: 10.1109/EMBC46164.2021.9630018  0.694
2021 Do JL, Allahwerdy S, David RCC, Weinreb RN, Tuszynski MH, Welsbie DS. Optic Nerve Engraftment of Neural Stem Cells. Investigative Ophthalmology & Visual Science. 62: 30. PMID 34283208 DOI: 10.1167/iovs.62.9.30  0.65
2021 Failli V, Kleitman N, Lammertse DP, Hsieh JTC, Steeves JD, Fawcett JW, Tuszynski MH, Curt A, Fehlings MG, Guest JD, Blight AR. Experimental Treatments for Spinal Cord Injury: What you Should Know. Topics in Spinal Cord Injury Rehabilitation. 27: 50-74. PMID 34108834 DOI: 10.46292/sci2702-50  0.333
2020 Poplawski GH, Tuszynski MH. Regeneration of Corticospinal Axons into Neural Progenitor Cell Grafts After Spinal Cord Injury. Neuroscience Insights. 15: 2633105520974000. PMID 33283187 DOI: 10.1177/2633105520974000  0.505
2020 Biscola NP, Christe KL, Rosenzweig ES, Tuszynski MH, Havton LA. Sexual dimorphism of detrusor function demonstrated by urodynamic studies in rhesus macaques. Scientific Reports. 10: 16170. PMID 32999325 DOI: 10.1038/s41598-020-73016-0  0.646
2020 Ceto S, Sekiguchi KJ, Takashima Y, Nimmerjahn A, Tuszynski MH. Neural Stem Cell Grafts Form Extensive Synaptic Networks that Integrate with Host Circuits after Spinal Cord Injury. Cell Stem Cell. PMID 32758426 DOI: 10.1016/J.Stem.2020.07.007  0.402
2020 Poplawski GHD, Kawaguchi R, Van Niekerk E, Lu P, Mehta N, Canete P, Lie R, Dragatsis I, Meves JM, Zheng B, Coppola G, Tuszynski MH. Injured adult neurons regress to an embryonic transcriptional growth state. Nature. 581: 77-82. PMID 32376949 DOI: 10.1038/S41586-020-2200-5  0.463
2019 Rosenzweig ES, Salegio EA, Liang JJ, Weber JL, Weinholtz CA, Brock JH, Moseanko R, Hawbecker S, Pender R, Cruzen CL, Iaci JF, Caggiano AO, Blight AR, Haenzi B, Huie JR, ... ... Tuszynski MH, et al. Chondroitinase improves anatomical and functional outcomes after primate spinal cord injury. Nature Neuroscience. PMID 31235933 DOI: 10.1038/S41593-019-0424-1  0.824
2019 Lu P, Gomes-Leal W, Anil S, Dobkins G, Huie JR, Ferguson AR, Graham L, Tuszynski M. Origins of Neural Progenitor Cell-Derived Axons Projecting Caudally after Spinal Cord Injury. Stem Cell Reports. PMID 31204300 DOI: 10.1016/J.Stemcr.2019.05.011  0.571
2019 Biane JS, Takashima Y, Conner JM, Scanziani M, Tuszynski MH. Reorganization of Recurrent Layer 5 Corticospinal Networks Following Adult Motor Training. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 30948479 DOI: 10.1523/Jneurosci.3442-17.2019  0.766
2019 Kumamaru H, Lu P, Rosenzweig ES, Kadoya K, Tuszynski MH. Regenerating Corticospinal Axons Innervate Phenotypically Appropriate Neurons within Neural Stem Cell Grafts. Cell Reports. 26: 2329-2339.e4. PMID 30811984 DOI: 10.1016/J.Celrep.2019.01.099  0.806
2019 Lien BV, Tuszynski MH, Lu P. Astrocytes migrate from human neural stem cell grafts and functionally integrate into the injured rat spinal cord. Experimental Neurology. PMID 30653967 DOI: 10.1016/j.expneurol.2019.01.006  0.382
2019 Koffler J, Zhu W, Qu X, Platoshyn O, Dulin JN, Brock J, Graham L, Lu P, Sakamoto J, Marsala M, Chen S, Tuszynski MH. Biomimetic 3D-printed scaffolds for spinal cord injury repair. Nature Medicine. PMID 30643285 DOI: 10.1038/S41591-018-0296-Z  0.798
2018 Kumamaru H, Lu P, Rosenzweig ES, Tuszynski MH. Activation of Intrinsic Growth State Enhances Host Axonal Regeneration into Neural Progenitor Cell Grafts. Stem Cell Reports. PMID 30197116 DOI: 10.1016/J.Stemcr.2018.08.009  0.8
2018 Kumamaru H, Kadoya K, Adler AF, Takashima Y, Graham L, Coppola G, Tuszynski MH. Generation and post-injury integration of human spinal cord neural stem cells. Nature Methods. PMID 30082899 DOI: 10.1038/s41592-018-0074-3  0.41
2018 Poplawski GHD, Lie R, Hunt M, Kumamaru H, Kawaguchi R, Lu P, Schäfer MKE, Woodruff G, Robinson J, Canete P, Dulin JN, Geoffroy CG, Menzel L, Zheng B, Coppola G, ... Tuszynski MH, et al. Adult rat myelin enhances axonal outgrowth from neural stem cells. Science Translational Medicine. 10. PMID 29794059 DOI: 10.1126/Scitranslmed.Aal2563  0.763
2018 Rosenzweig ES, Brock JH, Lu P, Kumamaru H, Salegio EA, Kadoya K, Weber JL, Liang JJ, Moseanko R, Hawbecker S, Huie JR, Havton LA, Nout-Lomas YS, Ferguson AR, Beattie MS, ... ... Tuszynski MH, et al. Restorative effects of human neural stem cell grafts on the primate spinal cord. Nature Medicine. PMID 29480894 DOI: 10.1038/Nm.4502  0.811
2018 Dulin JN, Adler AF, Kumamaru H, Poplawski GHD, Lee-Kubli C, Strobl H, Gibbs D, Kadoya K, Fawcett JW, Lu P, Tuszynski MH. Injured adult motor and sensory axons regenerate into appropriate organotypic domains of neural progenitor grafts. Nature Communications. 9: 84. PMID 29311559 DOI: 10.1038/S41467-017-02613-X  0.819
2017 Brock JH, Graham L, Staufenberg E, Im S, Tuszynski MH. Rodent Neural Progenitor Cells Support Functional Recovery After Cervical Spinal Cord Contusion. Journal of Neurotrauma. PMID 29279015 DOI: 10.1089/Neu.2017.5244  0.608
2017 Brock JH, Rosenzweig ES, Yang H, Tuszynski MH. Enhanced axonal transport: A novel form of "plasticity" after primate and rodent spinal cord injury. Experimental Neurology. 301: 59-69. PMID 29277625 DOI: 10.1016/J.Expneurol.2017.12.009  0.823
2017 Lu P, Ceto S, Wang Y, Graham L, Wu D, Kumamaru H, Staufenberg E, Tuszynski MH. Prolonged human neural stem cell maturation supports recovery in injured rodent CNS. The Journal of Clinical Investigation. PMID 28825600 DOI: 10.1172/Jci92955  0.37
2017 Hunt M, Lu P, Tuszynski MH. Myelination of axons emerging from neural progenitor grafts after spinal cord injury. Experimental Neurology. PMID 28698030 DOI: 10.1016/j.expneurol.2017.07.005  0.464
2017 Adler AF, Lee-Kubli C, Kumamaru H, Kadoya K, Tuszynski MH. Comprehensive Monosynaptic Rabies Virus Mapping of Host Connectivity with Neural Progenitor Grafts after Spinal Cord Injury. Stem Cell Reports. PMID 28479302 DOI: 10.1016/j.stemcr.2017.04.004  0.386
2017 Lu P, Tuszynski MH. Introduction to Neuroscience Letters Special Issue: "Plasticity and Regeneration After Spinal Cord Injury". Neuroscience Letters. PMID 28432027 DOI: 10.1016/j.neulet.2017.04.029  0.374
2017 Shahriari D, Koffler JY, Tuszynski MH, Campana WM, Sakamoto JS. Hierarchically Ordered Porous and High Volume poly caprolactone (PCL) Microchannel Scaffolds Enhanced Axon Growth in Transected Spinal Cords. Tissue Engineering. Part A. PMID 28107810 DOI: 10.1089/Ten.Tea.2016.0378  0.36
2016 Gao M, Lu P, Lynam D, Bednark B, Campana WM, Sakamoto J, Tuszynski M. BDNF gene delivery within and beyond templated agarose multi-channel guidance scaffolds enhances peripheral nerve regeneration. Journal of Neural Engineering. 13: 066011. PMID 27762235 DOI: 10.1088/1741-2560/13/6/066011  0.399
2016 Cai DJ, Aharoni D, Shuman T, Shobe J, Biane J, Song W, Wei B, Veshkini M, La-Vu M, Lou J, Flores SE, Kim I, Sano Y, Zhou M, Baumgaertel K, ... ... Tuszynski M, et al. A shared neural ensemble links distinct contextual memories encoded close in time. Nature. 534: 115-8. PMID 27251287 DOI: 10.1038/Nature17955  0.745
2016 Kadoya K, Lu P, Nguyen K, Lee-Kubli C, Kumamaru H, Yao L, Knackert J, Poplawski G, Dulin JN, Strobl H, Takashima Y, Biane J, Conner J, Zhang SC, Tuszynski MH. Spinal cord reconstitution with homologous neural grafts enables robust corticospinal regeneration. Nature Medicine. PMID 27019328 DOI: 10.1038/Nm.4066  0.853
2016 Biane JS, Takashima Y, Scanziani M, Conner JM, Tuszynski MH. Thalamocortical Projections onto Behaviorally Relevant Neurons Exhibit Plasticity during Adult Motor Learning. Neuron. PMID 26948893 DOI: 10.1016/J.Neuron.2016.02.001  0.779
2016 Chandran V, Coppola G, Nawabi H, Omura T, Versano R, Huebner EA, Zhang A, Costigan M, Yekkirala A, Barrett L, Blesch A, Michaelevski I, Davis-Turak J, Gao F, Langfelder P, ... ... Tuszynski M, et al. A Systems-Level Analysis of the Peripheral Nerve Intrinsic Axonal Growth Program. Neuron. PMID 26898779 DOI: 10.1016/J.Neuron.2016.01.034  0.789
2016 Salegio EA, Bresnahan JC, Sparrey CJ, Camisa W, Fischer J, Leasure J, Buckley J, Nout-Lomas YS, Rosenzweig ES, Moseanko R, Strand S, Hawbecker S, Lemoy MJ, Haefeli J, Ma X, ... ... Tuszynski MH, et al. A Unilateral Cervical Spinal Cord Contusion Injury Model in Non-Human Primates (Macaca mulatta). Journal of Neurotrauma. PMID 26788611 DOI: 10.1089/Neu.2015.3956  0.74
2015 van Niekerk EA, Tuszynski MH, Lu P, Dulin JN. Molecular and Cellular Mechanisms of Axonal Regeneration After Spinal Cord Injury. Molecular & Cellular Proteomics : McP. PMID 26695766 DOI: 10.1074/Mcp.R115.053751  0.769
2015 Shahriari D, Koffler J, Lynam DA, Tuszynski MH, Sakamoto JS. Characterizing the Degradation of Alginate Hydrogel for Use in Multilumen Scaffolds for Spinal Cord Repair. Journal of Biomedical Materials Research. Part A. PMID 26488452 DOI: 10.1002/Jbm.A.35600  0.331
2015 Dulin JN, Antunes-Martins A, Chandran V, Costigan M, Lerch JK, Willis DE, Tuszynski MH. Transcriptomic Approaches to Neural Repair. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 13860-7. PMID 26468186 DOI: 10.1523/Jneurosci.2599-15.2015  0.747
2015 Brock JH, Graham L, Staufenberg E, Collyer E, Koffler Y, Tuszynski MH. Bone Marrow Stromal Cell Intraspinal Transplants Fail to Improve Motor Outcomes in a Severe Model of Spinal Cord Injury. Journal of Neurotrauma. PMID 26414795 DOI: 10.1089/Neu.2015.4009  0.538
2015 Friedli L, Rosenzweig ES, Barraud Q, Schubert M, Dominici N, Awai L, Nielson JL, Musienko P, Nout-Lomas Y, Zhong H, Zdunowski S, Roy RR, Strand SC, van den Brand R, Havton LA, ... ... Tuszynski MH, et al. Pronounced species divergence in corticospinal tract reorganization and functional recovery after lateralized spinal cord injury favors primates. Science Translational Medicine. 7: 302ra134. PMID 26311729 DOI: 10.1126/Scitranslmed.Aac5811  0.761
2015 Tuszynski MH, Yang JH, Barba D, U HS, Bakay RA, Pay MM, Masliah E, Conner JM, Kobalka P, Roy S, Nagahara AH. Nerve Growth Factor Gene Therapy: Activation of Neuronal Responses in Alzheimer Disease. Jama Neurology. PMID 26302439 DOI: 10.1001/Jamaneurol.2015.1807  0.349
2015 Biane JS, Scanziani M, Tuszynski MH, Conner JM. Motor cortex maturation is associated with reductions in recurrent connectivity among functional subpopulations and increases in intrinsic excitability. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 4719-28. PMID 25788688 DOI: 10.1523/Jneurosci.2792-14.2015  0.797
2015 Ramanathan DS, Conner JM, Anilkumar AA, Tuszynski MH. Cholinergic systems are essential for late-stage maturation and refinement of motor cortical circuits. Journal of Neurophysiology. 113: 1585-97. PMID 25505106 DOI: 10.1152/jn.00408.2014  0.613
2014 Nielson JL, Haefeli J, Salegio EA, Liu AW, Guandique CF, Stück ED, Hawbecker S, Moseanko R, Strand SC, Zdunowski S, Brock JH, Roy RR, Rosenzweig ES, Nout-Lomas YS, Courtine G, ... ... Tuszynski MH, et al. Leveraging biomedical informatics for assessing plasticity and repair in primate spinal cord injury. Brain Research. PMID 25451131 DOI: 10.1016/J.Brainres.2014.10.048  0.787
2014 Biane J, Conner JM, Tuszynski MH. Nerve growth factor is primarily produced by GABAergic neurons of the adult rat cortex. Frontiers in Cellular Neuroscience. 8: 220. PMID 25147503 DOI: 10.3389/Fncel.2014.00220  0.776
2014 Lu P, Graham L, Wang Y, Wu D, Tuszynski M. Promotion of survival and differentiation of neural stem cells with fibrin and growth factor cocktails after severe spinal cord injury. Journal of Visualized Experiments : Jove. e50641. PMID 25145787 DOI: 10.3791/50641  0.52
2014 Lu P, Woodruff G, Wang Y, Graham L, Hunt M, Wu D, Boehle E, Ahmad R, Poplawski G, Brock J, Goldstein LS, Tuszynski MH. Long-distance axonal growth from human induced pluripotent stem cells after spinal cord injury. Neuron. 83: 789-96. PMID 25123310 DOI: 10.1016/J.Neuron.2014.07.014  0.649
2014 Tuszynski MH, Wang Y, Graham L, McHale K, Gao M, Wu D, Brock J, Blesch A, Rosenzweig ES, Havton LA, Zheng B, Conner JM, Marsala M, Lu P. Neural stem cells in models of spinal cord injury. Experimental Neurology. 261: 494-500. PMID 25079369 DOI: 10.1016/J.Expneurol.2014.07.011  0.83
2014 Nielson JL, Guandique CF, Liu AW, Burke DA, Lash AT, Moseanko R, Hawbecker S, Strand SC, Zdunowski S, Irvine KA, Brock JH, Nout-Lomas YS, Gensel JC, Anderson KD, Segal MR, ... ... Tuszynski MH, et al. Development of a database for translational spinal cord injury research. Journal of Neurotrauma. 31: 1789-99. PMID 25077610 DOI: 10.1089/Neu.2014.3399  0.745
2014 Lu P, Kadoya K, Tuszynski MH. Axonal growth and connectivity from neural stem cell grafts in models of spinal cord injury. Current Opinion in Neurobiology. 27: 103-9. PMID 24709371 DOI: 10.1016/j.conb.2014.03.010  0.464
2014 Tuszynski MH, Wang Y, Graham L, Gao M, Wu D, Brock J, Blesch A, Rosenzweig ES, Havton LA, Zheng B, Conner JM, Marsala M, Lu P. Neural stem cell dissemination after grafting to CNS injury sites. Cell. 156: 388-9. PMID 24485445 DOI: 10.1016/J.Cell.2014.01.016  0.828
2013 Do JL, Bonni A, Tuszynski MH. SnoN facilitates axonal regeneration after spinal cord injury. Plos One. 8: e71906. PMID 23936531 DOI: 10.1371/Journal.Pone.0071906  0.766
2013 Yoon C, Van Niekerk EA, Henry K, Ishikawa T, Orita S, Tuszynski MH, Campana WM. Low-density lipoprotein receptor-related protein 1 (LRP1)-dependent cell signaling promotes axonal regeneration. The Journal of Biological Chemistry. 288: 26557-68. PMID 23867460 DOI: 10.1074/Jbc.M113.478552  0.429
2013 Gao M, Lu P, Bednark B, Lynam D, Conner JM, Sakamoto J, Tuszynski MH. Templated agarose scaffolds for the support of motor axon regeneration into sites of complete spinal cord transection. Biomaterials. 34: 1529-36. PMID 23182350 DOI: 10.1016/J.Biomaterials.2012.10.070  0.511
2012 Yoon C, Tuszynski MH. Frontiers of spinal cord and spine repair: experimental approaches for repair of spinal cord injury. Advances in Experimental Medicine and Biology. 760: 1-15. PMID 23281510  0.435
2012 Blesch A, Fischer I, Tuszynski MH. Gene therapy, neurotrophic factors and spinal cord regeneration. Handbook of Clinical Neurology. 109: 563-74. PMID 23098737 DOI: 10.1016/B978-0-444-52137-8.00035-8  0.817
2012 Lu P, Wang Y, Graham L, McHale K, Gao M, Wu D, Brock J, Blesch A, Rosenzweig ES, Havton LA, Zheng B, Conner JM, Marsala M, Tuszynski MH. Long-distance growth and connectivity of neural stem cells after severe spinal cord injury. Cell. 150: 1264-73. PMID 22980985 DOI: 10.1016/J.Cell.2012.08.020  0.86
2012 Lu P, Blesch A, Graham L, Wang Y, Samara R, Banos K, Haringer V, Havton L, Weishaupt N, Bennett D, Fouad K, Tuszynski MH. Motor axonal regeneration after partial and complete spinal cord transection. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 8208-18. PMID 22699902 DOI: 10.1523/Jneurosci.0308-12.2012  0.851
2012 Tuszynski MH, Steward O. Concepts and methods for the study of axonal regeneration in the CNS. Neuron. 74: 777-91. PMID 22681683 DOI: 10.1016/j.neuron.2012.05.006  0.386
2012 Nout YS, Rosenzweig ES, Brock JH, Strand SC, Moseanko R, Hawbecker S, Zdunowski S, Nielson JL, Roy RR, Courtine G, Ferguson AR, Edgerton VR, Beattie MS, Bresnahan JC, Tuszynski MH. Animal models of neurologic disorders: a nonhuman primate model of spinal cord injury. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. 9: 380-92. PMID 22427157 DOI: 10.1007/S13311-012-0114-0  0.781
2012 Nout YS, Ferguson AR, Strand SC, Moseanko R, Hawbecker S, Zdunowski S, Nielson JL, Roy RR, Zhong H, Rosenzweig ES, Brock JH, Courtine G, Edgerton VR, Tuszynski MH, Beattie MS, et al. Methods for functional assessment after C7 spinal cord hemisection in the rhesus monkey. Neurorehabilitation and Neural Repair. 26: 556-69. PMID 22331214 DOI: 10.1177/1545968311421934  0.753
2012 Blesch A, Lu P, Tsukada S, Alto LT, Roet K, Coppola G, Geschwind D, Tuszynski MH. Conditioning lesions before or after spinal cord injury recruit broad genetic mechanisms that sustain axonal regeneration: superiority to camp-mediated effects. Experimental Neurology. 235: 162-73. PMID 22227059 DOI: 10.1016/J.Expneurol.2011.12.037  0.79
2012 Mehrotra S, Lynam D, Liu C, Shahriari D, Lee I, Tuszynski M, Sakamoto J, Chan C. Time controlled release of arabinofuranosylcytosine (Ara-C) from agarose hydrogels using layer-by-layer assembly: an in vitro study. Journal of Biomaterials Science. Polymer Edition. 23: 439-63. PMID 21294967 DOI: 10.1163/092050610X552221  0.353
2011 Hollis ER, Tuszynski MH. Neurotrophins: potential therapeutic tools for the treatment of spinal cord injury. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. 8: 694-703. PMID 21904786 DOI: 10.1007/S13311-011-0074-9  0.831
2011 Wang L, Conner JM, Rickert J, Tuszynski MH. Structural plasticity within highly specific neuronal populations identifies a unique parcellation of motor learning in the adult brain. Proceedings of the National Academy of Sciences of the United States of America. 108: 2545-50. PMID 21257908 DOI: 10.1073/Pnas.1014335108  0.783
2010 Rosenzweig ES, Courtine G, Jindrich DL, Brock JH, Ferguson AR, Strand SC, Nout YS, Roy RR, Miller DM, Beattie MS, Havton LA, Bresnahan JC, Edgerton VR, Tuszynski MH. Extensive spontaneous plasticity of corticospinal projections after primate spinal cord injury. Nature Neuroscience. 13: 1505-10. PMID 21076427 DOI: 10.1038/Nn.2691  0.822
2010 Brock JH, Rosenzweig ES, Blesch A, Moseanko R, Havton LA, Edgerton VR, Tuszynski MH. Local and remote growth factor effects after primate spinal cord injury. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 9728-37. PMID 20660255 DOI: 10.1523/Jneurosci.1924-10.2010  0.862
2010 Gros T, Sakamoto JS, Blesch A, Havton LA, Tuszynski MH. Regeneration of long-tract axons through sites of spinal cord injury using templated agarose scaffolds. Biomaterials. 31: 6719-29. PMID 20619785 DOI: 10.1016/J.Biomaterials.2010.04.035  0.814
2010 Giger RJ, Hollis ER, Tuszynski MH. Guidance molecules in axon regeneration. Cold Spring Harbor Perspectives in Biology. 2: a001867. PMID 20519341 DOI: 10.1101/Cshperspect.A001867  0.818
2010 Hollis ER, Jamshidi P, Lorenzana AO, Lee JK, Gray SJ, Samulski RJ, Zheng B, Tuszynski MH. Transient demyelination increases the efficiency of retrograde AAV transduction. Molecular Therapy : the Journal of the American Society of Gene Therapy. 18: 1496-500. PMID 20502445 DOI: 10.1038/Mt.2010.97  0.778
2010 Mehrotra S, Lynam D, Maloney R, Pawelec KM, Tuszynski MH, Lee I, Chan C, Sakamoto J. Time Controlled Protein Release from Layer-by-Layer Assembled Multilayer Functionalized Agarose Hydrogels. Advanced Functional Materials. 20: 247-258. PMID 20200599 DOI: 10.1002/Adfm.200901172  0.33
2010 Löw K, Blesch A, Herrmann J, Tuszynski MH. A dual promoter lentiviral vector for the in vivo evaluation of gene therapeutic approaches to axon regeneration after spinal cord injury. Gene Therapy. 17: 577-91. PMID 20200564 DOI: 10.1038/Gt.2010.14  0.8
2010 Nagahara AH, Mateling M, Eggert S, Blesch A, Rockenstein E, Koo EH, Masliah E, Tuszynski MH. P3-323: Early BDNF gene delivery into entorhinal cortex in APP transgenic mice ameliorates cells loss and preserves context-dependent fear conditioning Alzheimer's & Dementia. 6: S547-S547. DOI: 10.1016/J.Jalz.2010.05.1824  0.677
2010 Blesch A, Tuszynski MH. Neurotrophic Factor Therapy: NGF, BDNF and NT-3 Encyclopedia of Neuroscience. 1093-1100. DOI: 10.1016/B978-008045046-9.00030-9  0.691
2009 Kadoya K, Tsukada S, Lu P, Coppola G, Geschwind D, Filbin MT, Blesch A, Tuszynski MH. Combined intrinsic and extrinsic neuronal mechanisms facilitate bridging axonal regeneration one year after spinal cord injury. Neuron. 64: 165-72. PMID 19874785 DOI: 10.1016/J.Neuron.2009.09.016  0.816
2009 Alto LT, Havton LA, Conner JM, Hollis ER, Blesch A, Tuszynski MH. Chemotropic guidance facilitates axonal regeneration and synapse formation after spinal cord injury. Nature Neuroscience. 12: 1106-13. PMID 19648914 DOI: 10.1038/Nn.2365  0.852
2009 Ramanathan D, Tuszynski MH, Conner JM. The basal forebrain cholinergic system is required specifically for behaviorally mediated cortical map plasticity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 5992-6000. PMID 19420265 DOI: 10.1523/Jneurosci.0230-09.2009  0.605
2009 Blight A, Curt A, Ditunno JF, Dobkin B, Ellaway P, Fawcett J, Fehlings M, Grossman RG, Lammertse DP, Privat A, Steeves J, Tuszynski M, Kalichman M, Guest JD. Position statement on the sale of unproven cellular therapies for spinal cord injury: the international campaign for cures of spinal cord injury paralysis. Spinal Cord. 47: 713-4. PMID 19417762 DOI: 10.1038/Sc.2008.179  0.459
2009 Alfa RW, Tuszynski MH, Blesch A. A novel inducible tyrosine kinase receptor to regulate signal transduction and neurite outgrowth. Journal of Neuroscience Research. 87: 2624-31. PMID 19405107 DOI: 10.1002/Jnr.22101  0.729
2009 Hollis ER, Jamshidi P, Löw K, Blesch A, Tuszynski MH. Induction of corticospinal regeneration by lentiviral trkB-induced Erk activation. Proceedings of the National Academy of Sciences of the United States of America. 106: 7215-20. PMID 19359495 DOI: 10.1073/Pnas.0810624106  0.842
2009 Nagahara AH, Merrill DA, Coppola G, Tsukada S, Schroeder BE, Shaked GM, Wang L, Blesch A, Kim A, Conner JM, Rockenstein E, Chao MV, Koo EH, Geschwind D, Masliah E, ... ... Tuszynski MH, et al. Neuroprotective effects of brain-derived neurotrophic factor in rodent and primate models of Alzheimer's disease. Nature Medicine. 15: 331-7. PMID 19198615 DOI: 10.1038/Nm.1912  0.716
2009 Rosenzweig ES, Brock JH, Culbertson MD, Lu P, Moseanko R, Edgerton VR, Havton LA, Tuszynski MH. Extensive spinal decussation and bilateral termination of cervical corticospinal projections in rhesus monkeys. The Journal of Comparative Neurology. 513: 151-63. PMID 19125408 DOI: 10.1002/Cne.21940  0.818
2009 Nagahara AH, Bernot T, Moseanko R, Brignolo L, Blesch A, Conner JM, Ramirez A, Gasmi M, Tuszynski MH. Long-term reversal of cholinergic neuronal decline in aged non-human primates by lentiviral NGF gene delivery. Experimental Neurology. 215: 153-9. PMID 19013154 DOI: 10.1016/J.Expneurol.2008.10.004  0.72
2009 Blesch A, Tuszynski MH. Spinal cord injury: plasticity, regeneration and the challenge of translational drug development. Trends in Neurosciences. 32: 41-7. PMID 18977039 DOI: 10.1016/J.Tins.2008.09.008  0.764
2009 Hollis ER, Lu P, Blesch A, Tuszynski MH. IGF-I gene delivery promotes corticospinal neuronal survival but not regeneration after adult CNS injury. Experimental Neurology. 215: 53-9. PMID 18938163 DOI: 10.1016/J.Expneurol.2008.09.014  0.859
2009 Nagahara AH, Schroeder BE, Coppola G, Wang L, Blesch A, Rockenstein E, Geschwind D, Masliah E, Koo EH, Tuszynski MH. P2-219: Restorative effects of BDNF gene delivery into entorhinal cortex in APP transgenic mice Alzheimer's & Dementia. 5: P324-P325. DOI: 10.1016/J.Jalz.2009.04.532  0.678
2008 Hollis Ii ER, Kadoya K, Hirsch M, Samulski RJ, Tuszynski MH. Efficient Retrograde Neuronal Transduction Utilizing Self-complementary AAV1. Molecular Therapy : the Journal of the American Society of Gene Therapy. 16: 296-301. PMID 28178539 DOI: 10.1038/Sj.Mt.6300367  0.305
2008 Bishop KM, Hofer EK, Mehta A, Ramirez A, Sun L, Tuszynski M, Bartus RT. Therapeutic potential of CERE-110 (AAV2-NGF): targeted, stable, and sustained NGF delivery and trophic activity on rodent basal forebrain cholinergic neurons. Experimental Neurology. 211: 574-84. PMID 18439998 DOI: 10.1016/J.Expneurol.2008.03.004  0.38
2008 Löw K, Culbertson M, Bradke F, Tessier-Lavigne M, Tuszynski MH. Netrin-1 is a novel myelin-associated inhibitor to axon growth. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 1099-108. PMID 18234888 DOI: 10.1523/Jneurosci.4906-07.2008  0.497
2008 Hollis ER, Kadoya K, Hirsch M, Samulski RJ, Tuszynski MH. Efficient retrograde neuronal transduction utilizing self-complementary AAV1. Molecular Therapy : the Journal of the American Society of Gene Therapy. 16: 296-301. PMID 18223548 DOI: 10.1038/sj.mt.6300367  0.769
2008 Lu P, Tuszynski MH. Growth factors and combinatorial therapies for CNS regeneration. Experimental Neurology. 209: 313-20. PMID 17927983 DOI: 10.1016/j.expneurol.2007.08.004  0.438
2008 Tuszynski MH, Lu P. Axonal plasticity and regeneration in the injured spinal cord Cns Regeneration. 319-335. DOI: 10.1016/B978-012373994-0.50015-4  0.458
2008 Blesch A, Tuszynski MH. Neurotrophic factors in alzheimer's disease Cns Regeneration. 201-221. DOI: 10.1016/B978-012373994-0.50010-5  0.668
2008 Kordower JH, Tuszynski MH. CNS Regeneration Cns Regeneration.  0.302
2007 Blesch A, Tuszynski MH. Transient growth factor delivery sustains regenerated axons after spinal cord injury. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 10535-45. PMID 17898225 DOI: 10.1523/Jneurosci.1903-07.2007  0.819
2007 Fawcett JW, Curt A, Steeves JD, Coleman WP, Tuszynski MH, Lammertse D, Bartlett PF, Blight AR, Dietz V, Ditunno J, Dobkin BH, Havton LA, Ellaway PH, Fehlings MG, Privat A, et al. Guidelines for the conduct of clinical trials for spinal cord injury as developed by the ICCP panel: spontaneous recovery after spinal cord injury and statistical power needed for therapeutic clinical trials. Spinal Cord. 45: 190-205. PMID 17179973 DOI: 10.1038/Sj.Sc.3102007  0.334
2007 Lu P, Jones LL, Tuszynski MH. Axon regeneration through scars and into sites of chronic spinal cord injury. Experimental Neurology. 203: 8-21. PMID 17014846 DOI: 10.1016/j.expneurol.2006.07.030  0.446
2006 Stokols S, Sakamoto J, Breckon C, Holt T, Weiss J, Tuszynski MH. Templated agarose scaffolds support linear axonal regeneration. Tissue Engineering. 12: 2777-87. PMID 17518647 DOI: 10.1089/Ten.2006.12.2777  0.844
2006 Lu P, Yang H, Culbertson M, Graham L, Roskams AJ, Tuszynski MH. Olfactory ensheathing cells do not exhibit unique migratory or axonal growth-promoting properties after spinal cord injury. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 11120-30. PMID 17065452 DOI: 10.1523/Jneurosci.3264-06.2006  0.446
2006 Blurton-Jones M, Tuszynski MH. Estradiol-induced modulation of estrogen receptor-beta and GABA within the adult neocortex: a potential transsynaptic mechanism for estrogen modulation of BDNF. The Journal of Comparative Neurology. 499: 603-12. PMID 17029253 DOI: 10.1002/Cne.21122  0.568
2006 Taylor L, Jones L, Tuszynski MH, Blesch A. Neurotrophin-3 gradients established by lentiviral gene delivery promote short-distance axonal bridging beyond cellular grafts in the injured spinal cord. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 9713-21. PMID 16988042 DOI: 10.1523/Jneurosci.0734-06.2006  0.836
2006 Ramanathan D, Conner JM, Tuszynski MH. A form of motor cortical plasticity that correlates with recovery of function after brain injury. Proceedings of the National Academy of Sciences of the United States of America. 103: 11370-5. PMID 16837575 DOI: 10.1073/Pnas.0601065103  0.624
2006 Blight AR, Tuszynski MH. Clinical trials in spinal cord injury. Journal of Neurotrauma. 23: 586-93. PMID 16629639 DOI: 10.1089/Neu.2006.23.586  0.344
2006 Yang H, Lu P, McKay HM, Bernot T, Keirstead H, Steward O, Gage FH, Edgerton VR, Tuszynski MH. Endogenous neurogenesis replaces oligodendrocytes and astrocytes after primate spinal cord injury. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 2157-66. PMID 16495442 DOI: 10.1523/Jneurosci.4070-05.2005  0.561
2006 Stokols S, Tuszynski MH. Freeze-dried agarose scaffolds with uniaxial channels stimulate and guide linear axonal growth following spinal cord injury. Biomaterials. 27: 443-51. PMID 16099032 DOI: 10.1016/J.Biomaterials.2005.06.039  0.853
2006 Blesch A, Tuszynski MH. NGF gene therapy for Alzheimer's disease Experimental Neurology. 198: 561. DOI: 10.1016/J.Expneurol.2006.02.024  0.673
2005 Blesch A, Conner J, Pfeifer A, Gasmi M, Ramirez A, Britton W, Alfa R, Verma I, Tuszynski MH. Regulated lentiviral NGF gene transfer controls rescue of medial septal cholinergic neurons. Molecular Therapy : the Journal of the American Society of Gene Therapy. 11: 916-25. PMID 15922962 DOI: 10.1016/J.Ymthe.2005.01.007  0.732
2005 Tuszynski MH, Thal L, Pay M, Salmon DP, U HS, Bakay R, Patel P, Blesch A, Vahlsing HL, Ho G, Tong G, Potkin SG, Fallon J, Hansen L, Mufson EJ, et al. A phase 1 clinical trial of nerve growth factor gene therapy for Alzheimer disease. Nature Medicine. 11: 551-5. PMID 15852017 DOI: 10.1038/Nm1239  0.713
2005 Anderson DK, Beattie M, Blesch A, Bresnahan J, Bunge M, Dietrich D, Dietz V, Dobkin B, Fawcett J, Fehlings M, Fischer I, Grossman R, Guest J, Hagg T, Hall ED, ... ... Tuszynski MH, et al. Recommended guidelines for studies of human subjects with spinal cord injury. Spinal Cord. 43: 453-8. PMID 15824756 DOI: 10.1038/Sj.Sc.3101746  0.75
2005 Lu P, Jones LL, Tuszynski MH. BDNF-expressing marrow stromal cells support extensive axonal growth at sites of spinal cord injury. Experimental Neurology. 191: 344-60. PMID 15649491 DOI: 10.1016/j.expneurol.2004.09.018  0.492
2004 Steeves J, Fawcett J, Tuszynski M. Report of international clinical trials workshop on spinal cord injury February 20-21, 2004, Vancouver, Canada. Spinal Cord. 42: 591-7. PMID 15303119 DOI: 10.1038/Sj.Sc.3101669  0.421
2004 Lu P, Yang H, Jones LL, Filbin MT, Tuszynski MH. Combinatorial therapy with neurotrophins and cAMP promotes axonal regeneration beyond sites of spinal cord injury. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 6402-9. PMID 15254096 DOI: 10.1523/Jneurosci.1492-04.2004  0.526
2004 Blesch A, Tuszynski MH. Gene therapy and cell transplantation for Alzheimer's disease and spinal cord injury. Yonsei Medical Journal. 45: 28-31. PMID 15250047 DOI: 10.3349/Ymj.2004.45.Suppl.28  0.755
2004 Lu P, Blesch A, Tuszynski MH. Induction of bone marrow stromal cells to neurons: differentiation, transdifferentiation, or artifact? Journal of Neuroscience Research. 77: 174-91. PMID 15211585 DOI: 10.1002/Jnr.20148  0.714
2004 Stokols S, Tuszynski MH. The fabrication and characterization of linearly oriented nerve guidance scaffolds for spinal cord injury. Biomaterials. 25: 5839-46. PMID 15172496 DOI: 10.1016/J.Biomaterials.2004.01.041  0.84
2004 Lacroix S, Havton LA, McKay H, Yang H, Brant A, Roberts J, Tuszynski MH. Bilateral corticospinal projections arise from each motor cortex in the macaque monkey: a quantitative study. The Journal of Comparative Neurology. 473: 147-61. PMID 15101086 DOI: 10.1002/Cne.20051  0.423
2004 Blesch A, Tuszynski MH. Nucleus hears axon's pain. Nature Medicine. 10: 236-7. PMID 14991043 DOI: 10.1038/Nm0304-236  0.749
2004 Tuszynski MH, Blesch A. Nerve growth factor: from animal models of cholinergic neuronal degeneration to gene therapy in Alzheimer's disease. Progress in Brain Research. 146: 441-9. PMID 14699979 DOI: 10.1016/S0079-6123(03)46028-7  0.722
2004 Blurton-Jones M, Kuan PN, Tuszynski MH. Anatomical evidence for transsynaptic influences of estrogen on brain-derived neurotrophic factor expression. The Journal of Comparative Neurology. 468: 347-60. PMID 14681930 DOI: 10.1002/Cne.10989  0.584
2004 Bishop KM, Hofer K, Rius D, Mehta A, Lawandry S, Brown L, Kruegel B, Gasmi M, Tuszynski M, Bartus RT. 527. CERE-110, an AAV2-based vector to deliver NGF, provides trophic activity to basal forebrain cholinergic neurons in rats and cynomolgous monkeys Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.473  0.371
2003 Tobias CA, Shumsky JS, Shibata M, Tuszynski MH, Fischer I, Tessler A, Murray M. Delayed grafting of BDNF and NT-3 producing fibroblasts into the injured spinal cord stimulates sprouting, partially rescues axotomized red nucleus neurons from loss and atrophy, and provides limited regeneration. Experimental Neurology. 184: 97-113. PMID 14637084 DOI: 10.1016/S0014-4886(03)00394-7  0.479
2003 Blesch A, Tuszynski MH. Cellular GDNF delivery promotes growth of motor and dorsal column sensory axons after partial and complete spinal cord transections and induces remyelination. The Journal of Comparative Neurology. 467: 403-17. PMID 14608602 DOI: 10.1002/Cne.10934  0.829
2003 Jones LL, Sajed D, Tuszynski MH. Axonal regeneration through regions of chondroitin sulfate proteoglycan deposition after spinal cord injury: a balance of permissiveness and inhibition. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 9276-88. PMID 14561854  0.493
2003 Jones LL, Margolis RU, Tuszynski MH. The chondroitin sulfate proteoglycans neurocan, brevican, phosphacan, and versican are differentially regulated following spinal cord injury. Experimental Neurology. 182: 399-411. PMID 12895450 DOI: 10.1016/S0014-4886(03)00087-6  0.424
2003 Lu P, Jones LL, Snyder EY, Tuszynski MH. Neural stem cells constitutively secrete neurotrophic factors and promote extensive host axonal growth after spinal cord injury. Experimental Neurology. 181: 115-29. PMID 12781986 DOI: 10.1016/S0014-4886(03)00037-2  0.467
2003 Tuszynski MH, Grill R, Jones LL, Brant A, Blesch A, Löw K, Lacroix S, Lu P. NT-3 gene delivery elicits growth of chronically injured corticospinal axons and modestly improves functional deficits after chronic scar resection. Experimental Neurology. 181: 47-56. PMID 12710933 DOI: 10.1016/S0014-4886(02)00055-9  0.81
2002 Merrill DA, Blesch A, Tuszynski MH. Therapeutic potential of nervous system growth factors for neurodegenerative disease. Expert Review of Neurotherapeutics. 2: 89-96. PMID 19811018 DOI: 10.1586/14737175.2.1.89  0.714
2002 Lacroix S, Chang L, Rose-John S, Tuszynski MH. Delivery of hyper-interleukin-6 to the injured spinal cord increases neutrophil and macrophage infiltration and inhibits axonal growth. The Journal of Comparative Neurology. 454: 213-28. PMID 12442313 DOI: 10.1002/cne.10407  0.393
2002 Blesch A, Tuszynski MH. Spontaneous and neurotrophin-induced axonal plasticity after spinal cord injury. Progress in Brain Research. 137: 415-23. PMID 12440384 DOI: 10.1016/S0079-6123(02)37033-X  0.833
2002 Tuszynski MH, Conner J, Blesch A, Smith D, Merrill DA, Vahlsing HL. New strategies in neural repair. Progress in Brain Research. 138: 401-9. PMID 12432780 DOI: 10.1016/S0079-6123(02)38089-0  0.666
2002 Blurton-Jones M, Tuszynski MH. Estrogen receptor-beta colocalizes extensively with parvalbumin-labeled inhibitory neurons in the cortex, amygdala, basal forebrain, and hippocampal formation of intact and ovariectomized adult rats. The Journal of Comparative Neurology. 452: 276-87. PMID 12353223 DOI: 10.1002/Cne.10393  0.556
2002 Tuszynski MH, Thal L, U HS, Pay MM, Blesch A, Conner J, Vahlsing HL. Nerve growth factor gene therapy for Alzheimer's disease. Journal of Molecular Neuroscience : Mn. 19: 207. PMID 12212782 DOI: 10.1007/S12031-002-0034-2  0.695
2002 Tuszynski MH, Grill R, Jones LL, McKay HM, Blesch A. Spontaneous and augmented growth of axons in the primate spinal cord: effects of local injury and nerve growth factor-secreting cell grafts. The Journal of Comparative Neurology. 449: 88-101. PMID 12115695 DOI: 10.1002/Cne.10266  0.816
2002 Jones LL, Tuszynski MH. Spinal cord injury elicits expression of keratan sulfate proteoglycans by macrophages, reactive microglia, and oligodendrocyte progenitors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 4611-24. PMID 12040068  0.428
2002 Blesch A, Lu P, Tuszynski MH. Neurotrophic factors, gene therapy, and neural stem cells for spinal cord repair. Brain Research Bulletin. 57: 833-8. PMID 12031281 DOI: 10.1016/S0361-9230(01)00774-2  0.81
2002 Jones LL, Yamaguchi Y, Stallcup WB, Tuszynski MH. NG2 is a major chondroitin sulfate proteoglycan produced after spinal cord injury and is expressed by macrophages and oligodendrocyte progenitors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 2792-803. PMID 11923444  0.443
2002 Weidner N, Tuszynski MH. Spontaneous plasticity in the injured spinal cord-implications for repair strategies. Molecular Psychiatry. 7: 9-11. PMID 11803438 DOI: 10.1038/sj.mp.4001983  0.331
2001 Jones LL, Tuszynski MH. Chronic intrathecal infusions after spinal cord injury cause scarring and compression. Microscopy Research and Technique. 54: 317-24. PMID 11514988 DOI: 10.1002/jemt.1144  0.36
2001 Lu P, Blesch A, Tuszynski MH. Neurotrophism without neurotropism: BDNF promotes survival but not growth of lesioned corticospinal neurons. The Journal of Comparative Neurology. 436: 456-70. PMID 11447589 DOI: 10.1002/Cne.1080  0.815
2001 Blesch A, Tuszynski MH. GDNF gene delivery to injured adult CNS motor neurons promotes axonal growth, expression of the trophic neuropeptide CGRP, and cellular protection. The Journal of Comparative Neurology. 436: 399-410. PMID 11447585 DOI: 10.1002/Cne.1076  0.797
2001 Blesch A, Conner JM, Tuszynski MH. Modulation of neuronal survival and axonal growth in vivo by tetracycline-regulated neurotrophin expression. Gene Therapy. 8: 954-60. PMID 11426336 DOI: 10.1038/Sj.Gt.3301480  0.784
2001 Jones LL, Oudega M, Bunge MB, Tuszynski MH. Neurotrophic factors, cellular bridges and gene therapy for spinal cord injury. The Journal of Physiology. 533: 83-9. PMID 11351016 DOI: 10.1111/J.1469-7793.2001.0083B.X  0.514
2001 Blurton-Jones M, Tuszynski MH. Reactive astrocytes express estrogen receptors in the injured primate brain. The Journal of Comparative Neurology. 433: 115-23. PMID 11283953 DOI: 10.1002/Cne.1129  0.583
2001 Weidner N, Ner A, Salimi N, Tuszynski MH. Spontaneous corticospinal axonal plasticity and functional recovery after adult central nervous system injury. Proceedings of the National Academy of Sciences of the United States of America. 98: 3513-8. PMID 11248109 DOI: 10.1073/pnas.051626798  0.454
2000 Lacroix S, Tuszynski MH. Neurotrophic factors and gene therapy in spinal cord injury. Neurorehabilitation and Neural Repair. 14: 265-75. PMID 11402877 DOI: 10.1310/9A0A-E7P8-Bapd-L8Pm  0.566
2000 Tuszynski MH. Intraparenchymal NGF infusions rescue degenerating cholinergic neurons. Cell Transplantation. 9: 629-36. PMID 11144960  0.344
2000 Bowes M, Tuszynski MH, Conner J, Zivin JA. Continuous intrathecal fluid infusions elevate nerve growth factor levels and prevent functional deficits after spinal cord ischemia. Brain Research. 883: 178-83. PMID 11074046 DOI: 10.1016/S0006-8993(00)02779-7  0.366
2000 Blesch A, Uy HS, Diergardt N, Tuszynski MH. Neurite outgrowth can be modulated in vitro using a tetracycline-repressible gene therapy vector expressing human nerve growth factor. Journal of Neuroscience Research. 59: 402-9. PMID 10679776 DOI: 10.1002/(Sici)1097-4547(20000201)59:3<402::Aid-Jnr14>3.0.Co;2-Q  0.733
2000 Smith D, Roberts J, Gage F, Tuszynski M. 27. Reversal of spontaneous atrophy of cholinergic basal forebrain neurons in the aged primate by ex vivo gene therapy Biological Psychiatry. 47: S7-S8. DOI: 10.1016/S0006-3223(00)00293-6  0.384
2000 Tuszynski MH. Spinal Cord Injury Regeneration Research: Foreword Topics in Spinal Cord Injury Rehabilitation. 6: vii-x.  0.362
1999 Tuszynski M, Edgerton R, Dobkin B. Recovery of locomotion after experimental spinal cord injury: axonal regeneration or modulation of intrinsic spinal cord walking circuitry? The Journal of Spinal Cord Medicine. 22: 143. PMID 10826273 DOI: 10.1080/10790268.1999.11719563  0.528
1999 Weidner N, Grill RJ, Tuszynski MH. Elimination of basal lamina and the collagen "scar" after spinal cord injury fails to augment corticospinal tract regeneration. Experimental Neurology. 160: 40-50. PMID 10630189 DOI: 10.1006/exnr.1999.7200  0.777
1999 Weidner N, Blesch A, Grill RJ, Tuszynski MH. Nerve growth factor-hypersecreting Schwann cell grafts augment and guide spinal cord axonal growth and remyelinate central nervous system axons in a phenotypically appropriate manner that correlates with expression of L1. The Journal of Comparative Neurology. 413: 495-506. PMID 10495438 DOI: 10.1002/(Sici)1096-9861(19991101)413:4<495::Aid-Cne1>3.0.Co;2-Z  0.853
1999 Smith DE, Roberts J, Gage FH, Tuszynski MH. Age-associated neuronal atrophy occurs in the primate brain and is reversible by growth factor gene therapy. Proceedings of the National Academy of Sciences of the United States of America. 96: 10893-8. PMID 10485922 DOI: 10.1073/pnas.96.19.10893  0.4
1999 Tuszynski MH, Gabriel K, Gerhardt K, Szollar S. Human spinal cord retains substantial structural mass in chronic stages after injury. Journal of Neurotrauma. 16: 523-31. PMID 10391368  0.388
1999 Blesch A, Uy HS, Grill RJ, Cheng JG, Patterson PH, Tuszynski MH. Leukemia inhibitory factor augments neurotrophin expression and corticospinal axon growth after adult CNS injury. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 3556-66. PMID 10212315 DOI: 10.1523/Jneurosci.19-09-03556.1999  0.852
1999 Blurton-Jones MM, Roberts JA, Tuszynski MH. Estrogen receptor immunoreactivity in the adult primate brain: neuronal distribution and association with p75, trkA, and choline acetyltransferase. The Journal of Comparative Neurology. 405: 529-42. PMID 10098943 DOI: 10.1002/(Sici)1096-9861(19990322)405:4<529::Aid-Cne6>3.0.Co;2-Y  0.575
1998 Blesch A, Grill RJ, Tuszynski MH. Neurotrophin gene therapy in CNS models of trauma and degeneration. Progress in Brain Research. 117: 473-84. PMID 9932426 DOI: 10.1016/S0079-6123(08)64033-9  0.834
1998 Tuszynski MH, Weidner N, McCormack M, Miller I, Powell H, Conner J. Grafts of genetically modified Schwann cells to the spinal cord: survival, axon growth, and myelination. Cell Transplantation. 7: 187-96. PMID 9588600 DOI: 10.1016/S0963-6897(97)00166-8  0.448
1997 Grill RJ, Blesch A, Tuszynski MH. Robust growth of chronically injured spinal cord axons induced by grafts of genetically modified NGF-secreting cells. Experimental Neurology. 148: 444-52. PMID 9417824 DOI: 10.1006/Exnr.1997.6704  0.867
1997 Grill R, Murai K, Blesch A, Gage FH, Tuszynski MH. Cellular delivery of neurotrophin-3 promotes corticospinal axonal growth and partial functional recovery after spinal cord injury. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 5560-72. PMID 9204937  0.452
1997 Tuszynski MH, Murai K, Blesch A, Grill R, Miller I. Functional characterization of NGF-secreting cell grafts to the acutely injured spinal cord. Cell Transplantation. 6: 361-8. PMID 9171168 DOI: 10.1016/S0963-6897(97)00021-3  0.821
1997 Winkler J, Ramirez GA, Kuhn HG, Peterson DA, Day-Lollini PA, Stewart GR, Tuszynski MH, Gage FH, Thal LJ. Reversible Schwann cell hyperplasia and sprouting of sensory and sympathetic neurites after intraventricular administration of nerve growth factor. Annals of Neurology. 41: 82-93. PMID 9005869 DOI: 10.1002/ana.410410114  0.611
1997 Grill R, Murai K, Blesch A, Gage FH, Tuszynski MH. Cellular Delivery of Neurotrophin-3 Promotes Corticospinal Axonal Growth and Partial Functional Recovery after Spinal Cord Injury The Journal of Neuroscience. 17: 5560-5572. DOI: 10.1523/Jneurosci.17-14-05560.1997  0.816
1996 Tuszynski MH, Mafong E, Meyer S. Central infusions of brain-derived neurotrophic factor and neurotrophin-4/5, but not nerve growth factor and neurotrophin-3, prevent loss of the cholinergic phenotype in injured adult motor neurons. Neuroscience. 71: 761-71. PMID 8867048 DOI: 10.1016/0306-4522(95)00440-8  0.322
1996 Tuszynski MH, Gage FH. Somatic gene therapy for nervous system disease. Ciba Foundation Symposium. 196: 85-94; discussion 94. PMID 8866129 DOI: 10.1002/9780470514863.CH7  0.477
1996 Tuszynski MH, Roberts J, Senut MC, U HS, Gage FH. Gene therapy in the adult primate brain: intraparenchymal grafts of cells genetically modified to produce nerve growth factor prevent cholinergic neuronal degeneration. Gene Therapy. 3: 305-14. PMID 8732162  0.305
1996 Nakahara Y, Gage FH, Tuszynski MH. Grafts of fibroblasts genetically modified to secrete NGF, BDNF, NT-3, or basic FGF elicit differential responses in the adult spinal cord. Cell Transplantation. 5: 191-204. PMID 8689031 DOI: 10.1016/0963-6897(95)02028-4  0.604
1996 Tuszynski MH, Gabriel K, Gage FH, Suhr S, Meyer S, Rosetti A. Nerve growth factor delivery by gene transfer induces differential outgrowth of sensory, motor, and noradrenergic neurites after adult spinal cord injury. Experimental Neurology. 137: 157-73. PMID 8566208 DOI: 10.1006/exnr.1996.0016  0.604
1996 Nakahara Y, Gage FH, Tuszynski MH. Grafts of Fibroblasts Genetically Modified to Secrete Ngf, Bdnf, Nt-3, or Basic Fgf Elicit Differential Responses in the Adult Spinal Cord Cell Transplantation. 5: 191-204. DOI: 10.1177/096368979600500209  0.494
1995 Blesch A, Tuszynski M. Ex vivo gene therapy for Alzheimer's disease and spinal cord injury. Clinical Neuroscience (New York, N.Y.). 3: 268-74. PMID 8914793  0.803
1995 Tuszynski MH, Gage FH. Bridging grafts and transient nerve growth factor infusions promote long-term central nervous system neuronal rescue and partial functional recovery. Proceedings of the National Academy of Sciences of the United States of America. 92: 4621-5. PMID 7753852 DOI: 10.1073/PNAS.92.10.4621  0.538
1995 Tuszynski MH, Gage FH. Maintaining the neuronal phenotype after injury in the adult CNS. Neurotrophic factors, axonal growth substrates, and gene therapy. Molecular Neurobiology. 10: 151-67. PMID 7576305 DOI: 10.1007/BF02740673  0.545
1995 Senut MC, Tuszynski MH, Raymon HK, Suhr ST, Liou NH, Jones KR, Reichardt LF, Gage FH. Regional differences in responsiveness of adult CNS axons to grafts of cells expressing human neurotrophin 3. Experimental Neurology. 135: 36-55. PMID 7556552 DOI: 10.1006/exnr.1995.1064  0.567
1994 Tuszynski MH, Gage FH. Neurotrophic factors and diseases of the nervous system. Annals of Neurology. 35: S9-12. PMID 8185304 DOI: 10.1002/ana.410350705  0.461
1994 Tuszynski MH, Peterson DA, Ray J, Baird A, Nakahara Y, Gage FH. Fibroblasts genetically modified to produce nerve growth factor induce robust neuritic ingrowth after grafting to the spinal cord. Experimental Neurology. 126: 1-14. PMID 8157119 DOI: 10.1006/Exnr.1994.1037  0.611
1993 Hainline B, Posner JB, Tuszynski MH. Re: Spinal cord ataxia Neurology. 43: 1623. PMID 8240525  0.311
1993 Hainline B, Posner JB, Tuszynski MH. Spinal cord ataxia Neurology. 43: 1623-1623. DOI: 10.1212/WNL.43.8.1623-a  0.311
1991 Gage FH, Tuszynski MH, Chen KS, Fagan AM, Higgins GA. Nerve growth factor function in the central nervous system. Current Topics in Microbiology and Immunology. 165: 71-93. PMID 2032465 DOI: 10.1007/978-3-642-75747-1_5  0.401
1991 Tuszynski MH, Gage FH. In vivo assay of neuron-specific effects of nerve growth factor. Methods in Enzymology. 198: 35-48. PMID 1857228 DOI: 10.1016/0076-6879(91)98006-R  0.429
1990 Tuszynski MH, Armstrong DM, Gage FH. Basal forebrain cell loss following fimbria/fornix transection. Brain Research. 508: 241-8. PMID 2306615 DOI: 10.1016/0006-8993(90)90402-W  0.417
1990 Tuszynski MH, U HS, Amaral DG, Gage FH. Nerve growth factor infusion in the primate brain reduces lesion-induced cholinergic neuronal degeneration. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 10: 3604-14. PMID 2230949 DOI: 10.1523/Jneurosci.10-11-03604.1990  0.447
1990 Gage FH, Rosenberg MB, Tuszynski MH, Yoshida K, Armstrong DM, Hayes RC, Friedmann T. Gene therapy in the CNS: intracerebral grafting of genetically modified cells. Progress in Brain Research. 86: 205-17. PMID 2087558 DOI: 10.1016/S0079-6123(08)63178-7  0.408
1990 Gage FH, Fisher LJ, Jinnah HA, Rosenberg MB, Tuszynski MH, Friedmann T. Grafting genetically modified cells to the brain: conceptual and technical issues. Progress in Brain Research. 82: 1-10. PMID 1981271 DOI: 10.1016/S0079-6123(08)62584-4  0.384
1990 Tuszynski MH, Buzsaki G, Gage FH. Nerve growth factor infusions combined with fetal hippocampal grafts enhance reconstruction of the lesioned septohippocampal projection. Neuroscience. 36: 33-44. PMID 1699159 DOI: 10.1016/0306-4522(90)90349-9  0.424
1989 Tuszynski MH, Jinnah HA, Gage FH. Delivery of neuroactive compounds to the brain: potential utility of genetically modified cells. Neurobiology of Aging. 10: 644-5; discussion 64. PMID 2812247 DOI: 10.1016/0197-4580(89)90165-6  0.369
1989 Chen KS, Tuszynski MH, Gage FH. Role of neurotrophic factors in Alzheimer's disease. Neurobiology of Aging. 10: 545-6; discussion 55. PMID 2812224 DOI: 10.1016/0197-4580(89)90124-3  0.397
1989 Gage FH, Tuszynski MH, Chen KS, Armstrong D, Buzsáki G. Survival, growth and function of damaged cholinergic neurons. Exs. 57: 259-74. PMID 2533097 DOI: 10.1007/978-3-0348-9138-7_26  0.493
1988 Rosenberg MB, Friedmann T, Robertson RC, Tuszynski M, Wolff JA, Breakefield XO, Gage FH. Grafting genetically modified cells to the damaged brain: restorative effects of NGF expression. Science (New York, N.Y.). 242: 1575-8. PMID 3201248 DOI: 10.1126/Science.3201248  0.55
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