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Rita Sattler - Publications

Affiliations: 
Johns Hopkins University, Baltimore, MD 
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49 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Godfrey RK, Alsop E, Bjork RT, Chauhan BS, Ruvalcaba HC, Antone J, Gittings LM, Michael AF, Williams C, Hala'ufia G, Blythe AD, Hall M, Sattler R, Van Keuren-Jensen K, Zarnescu DC. Modelling TDP-43 proteinopathy in Drosophila uncovers shared and neuron-specific targets across ALS and FTD relevant circuits. Acta Neuropathologica Communications. 11: 168. PMID 37864255 DOI: 10.1186/s40478-023-01656-0  0.356
2023 Sattler R, Traynor BJ, Robertson J, Van Den Bosch L, Barmada SJ, Svendsen CN, Disney MD, Gendron TF, Wong PC, Turner MR, Boxer A, Babu S, Benatar M, Kurnellas M, Rohrer JD, et al. Roadmap for C9ORF72 in Frontotemporal Dementia and Amyotrophic Lateral Sclerosis: Report on the C9ORF72 FTD/ALS Summit. Neurology and Therapy. PMID 37847372 DOI: 10.1007/s40120-023-00548-8  0.353
2023 Gittings LM, Alsop EB, Antone J, Singer M, Whitsett TG, Sattler R, Van Keuren-Jensen K. Cryptic exon detection and transcriptomic changes revealed in single-nuclei RNA sequencing of C9ORF72 patients spanning the ALS-FTD spectrum. Acta Neuropathologica. PMID 37466726 DOI: 10.1007/s00401-023-02599-5  0.385
2023 Lorenzini I, Alsop E, Levy J, Gittings LM, Lall D, Rabichow BE, Moore S, Pevey R, Bustos LM, Burciu C, Bhatia D, Singer M, Saul J, McQuade A, Tzioras M, ... ... Sattler R, et al. Moderate intrinsic phenotypic alterations in ALS/FTD iPSC-microglia despite the presence of C9orf72 pathological features. Frontiers in Cellular Neuroscience. 17: 1179796. PMID 37346371 DOI: 10.3389/fncel.2023.1179796  0.672
2021 Lall D, Lorenzini I, Mota TA, Bell S, Mahan TE, Ulrich JD, Davtyan H, Rexach JE, Muhammad AKMG, Shelest O, Landeros J, Vazquez M, Kim J, Ghaffari L, O'Rourke JG, ... ... Sattler R, et al. C9orf72 deficiency promotes microglial-mediated synaptic loss in aging and amyloid accumulation. Neuron. PMID 34133945 DOI: 10.1016/j.neuron.2021.05.020  0.372
2021 Lall D, Lorenzini I, Mota TA, Bell S, Mahan TE, Ulrich JD, Davtyan H, Rexach JE, Muhammad AKMG, Shelest O, Landeros J, Vazquez M, Kim J, Ghaffari L, O'Rourke JG, ... ... Sattler R, et al. C9orf72 deficiency promotes microglial-mediated synaptic loss in aging and amyloid accumulation. Neuron. PMID 34133945 DOI: 10.1016/j.neuron.2021.05.020  0.372
2020 Gittings LM, Sattler R. Recent advances in understanding amyotrophic lateral sclerosis and emerging therapies. Faculty Reviews. 9: 12. PMID 33659944 DOI: 10.12703/b/9-12  0.703
2020 Bakkar N, Starr A, Rabichow BE, Lorenzini I, McEachin ZT, Kraft R, Chaung M, Macklin-Isquierdo S, Wingfield T, Carhart B, Zahler N, Chang WH, Bassell GJ, Betourne A, Boulis N, ... ... Sattler R, et al. The M1311V variant of ATP7A is associated with impaired trafficking and copper homeostasis in models of motor neuron disease. Neurobiology of Disease. 105228. PMID 33359139 DOI: 10.1016/j.nbd.2020.105228  0.32
2020 Moore S, Rabichow BE, Sattler R. The Hitchhiker's Guide to Nucleocytoplasmic Trafficking in Neurodegeneration. Neurochemical Research. PMID 32086712 DOI: 10.1007/S11064-020-02989-1  0.342
2019 Moore S, Alsop E, Lorenzini I, Starr A, Rabichow BE, Mendez E, Levy JL, Burciu C, Reiman R, Chew J, Belzil VV, Dickson D, Robertson J, Staats KA, Ichida JK, ... ... Sattler R, et al. Correction to: ADAR2 mislocalization and widespread RNA editing aberrations in C9orf72-mediated ALS/FTD. Acta Neuropathologica. PMID 31559488 DOI: 10.1007/S00401-019-02076-Y  0.346
2019 Manzo E, Lorenzini I, Barrameda D, O'Conner AG, Barrows JM, Starr A, Kovalik T, Rabichow BE, Lehmkuhl EM, Shreiner DD, Joardar A, Liévens JC, Bowser R, Sattler R, Zarnescu DC. Glycolysis upregulation is neuroprotective as a compensatory mechanism in ALS. Elife. 8. PMID 31180318 DOI: 10.7554/Elife.45114  0.44
2019 Moore S, Alsop E, Lorenzini I, Starr A, Rabichow BE, Mendez E, Levy JL, Burciu C, Reiman R, Chew J, Belzil VV, W Dickson D, Robertson J, Staats KA, Ichida JK, ... ... Sattler R, et al. ADAR2 mislocalization and widespread RNA editing aberrations in C9orf72-mediated ALS/FTD. Acta Neuropathologica. PMID 30945056 DOI: 10.1007/S00401-019-01999-W  0.433
2019 Xu W, Bao P, Jiang X, Wang H, Qin M, Wang R, Wang T, Yang Y, Lorenzini I, Liao L, Sattler R, Xu J. Reactivation of nonsense-mediated mRNA decay protects against C9orf72 dipeptide-repeat neurotoxicity. Brain : a Journal of Neurology. PMID 30938419 DOI: 10.1093/Brain/Awz070  0.421
2019 Miller SJ, Philips T, Kim N, Dastgheyb R, Chen Z, Hsieh YC, Daigle JG, Datta M, Chew J, Vidensky S, Pham JT, Hughes EG, Robinson MB, Sattler R, Tomer R, et al. Molecularly defined cortical astroglia subpopulation modulates neurons via secretion of Norrin. Nature Neuroscience. PMID 30936556 DOI: 10.1038/S41593-019-0366-7  0.427
2019 Manzo E, Lorenzini I, Barrameda D, O'Conner AG, Barrows JM, Starr A, Kovalik T, Rabichow BE, Lehmkuhl EM, Shreiner DD, Joardar A, Liévens J, Bowser R, Sattler R, Zarnescu DC. Author response: Glycolysis upregulation is neuroprotective as a compensatory mechanism in ALS Elife. DOI: 10.7554/Elife.45114.037  0.363
2018 Lorenzini I, Moore S, Sattler R. RNA Editing Deficiency in Neurodegeneration. Advances in Neurobiology. 20: 63-83. PMID 29916016 DOI: 10.1007/978-3-319-89689-2_3  0.333
2018 Ghaffari LT, Starr A, Nelson AT, Sattler R. Representing Diversity in the Dish: Using Patient-DerivedModels to Recreate the Heterogeneity of Neurological Disease. Frontiers in Neuroscience. 12: 56. PMID 29479303 DOI: 10.3389/Fnins.2018.00056  0.422
2018 Starr A, Sattler R. Synaptic dysfunction and altered excitability in C9ORF72 ALS/FTD. Brain Research. PMID 29453960 DOI: 10.1016/J.Brainres.2018.02.011  0.501
2018 Chou CC, Zhang Y, Umoh ME, Vaughan SW, Lorenzini I, Liu F, Sayegh M, Donlin-Asp PG, Chen YH, Duong DM, Seyfried NT, Powers MA, Kukar T, Hales CM, Gearing M, ... ... Sattler R, et al. TDP-43 pathology disrupts nuclear pore complexes and nucleocytoplasmic transport in ALS/FTD. Nature Neuroscience. PMID 29311743 DOI: 10.1038/S41593-017-0047-3  0.466
2017 Bakkar N, Kovalik T, Lorenzini I, Spangler S, Lacoste A, Sponaugle K, Ferrante P, Argentinis E, Sattler R, Bowser R. Artificial intelligence in neurodegenerative disease research: use of IBM Watson to identify additional RNA-binding proteins altered in amyotrophic lateral sclerosis. Acta Neuropathologica. PMID 29134320 DOI: 10.1007/S00401-017-1785-8  0.458
2017 Coyne AN, Lorenzini I, Chou CC, Torvund M, Rogers RS, Starr A, Zaepfel BL, Levy J, Johannesmeyer J, Schwartz JC, Nishimune H, Zinsmaier K, Rossoll W, Sattler R, Zarnescu DC. Post-transcriptional Inhibition of Hsc70-4/HSPA8 Expression Leads to Synaptic Vesicle Cycling Defects in Multiple Models of ALS. Cell Reports. 21: 110-125. PMID 28978466 DOI: 10.1016/J.Celrep.2017.09.028  0.499
2015 Ghosh M, Lane M, Krizman E, Sattler R, Rothstein JD, Robinson MB. Transcription Factor Pax6 Contributes to Induction of GLT-1 Expression in Astrocytes Through an Interaction with a Distal Enhancer Element. Journal of Neurochemistry. PMID 26485579 DOI: 10.1111/Jnc.13406  0.39
2015 Zhang K, Donnelly CJ, Haeusler AR, Grima JC, Machamer JB, Steinwald P, Daley EL, Miller SJ, Cunningham KM, Vidensky S, Gupta S, Thomas MA, Hong I, Chiu SL, Huganir RL, ... ... Sattler R, et al. The C9orf72 repeat expansion disrupts nucleocytoplasmic transport. Nature. 525: 56-61. PMID 26308891 DOI: 10.1038/Nature14973  0.723
2015 Zhang PW, Haidet-Phillips AM, Pham JT, Lee Y, Huo Y, Tienari PJ, Maragakis NJ, Sattler R, Rothstein JD. Generation of GFAP::GFP astrocyte reporter lines from human adult fibroblast-derived iPS cells using zinc-finger nuclease technology. Glia. PMID 26295203 DOI: 10.1002/Glia.22903  0.379
2015 Thomas AG, Sattler R, Tendyke K, Loiacono KA, Hansen H, Sahni V, Hashizume Y, Rojas C, Slusher BS. High-Throughput Assay Development for Cystine-Glutamate Antiporter (xc-) Highlights Faster Cystine Uptake than Glutamate Release in Glioma Cells. Plos One. 10: e0127785. PMID 26252954 DOI: 10.1371/Journal.Pone.0127785  0.338
2015 Li Y, Balasubramanian U, Cohen D, Zhang PW, Mosmiller E, Sattler R, Maragakis NJ, Rothstein JD. A comprehensive library of familial human amyotrophic lateral sclerosis induced pluripotent stem cells. Plos One. 10: e0118266. PMID 25760436 DOI: 10.1371/Journal.Pone.0118266  0.414
2015 Mendez EF, Sattler R. Biomarker development for C9orf72 repeat expansion in ALS. Brain Research. 1607: 26-35. PMID 25261695 DOI: 10.1016/J.Brainres.2014.09.041  0.391
2014 Donnelly CJ, Grima JC, Sattler R. Aberrant RNA homeostasis in amyotrophic lateral sclerosis: potential for new therapeutic targets? Neurodegenerative Disease Management. 4: 417-37. PMID 25531686 DOI: 10.2217/Nmt.14.36  0.459
2014 Abazyan S, Yang EJ, Abazyan B, Xia M, Yang C, Rojas C, Slusher B, Sattler R, Pletnikov M. Mutant disrupted-in-schizophrenia 1 in astrocytes: focus on glutamate metabolism. Journal of Neuroscience Research. 92: 1659-68. PMID 25131692 DOI: 10.1002/Jnr.23459  0.325
2014 Haeusler AR, Donnelly CJ, Periz G, Simko EA, Shaw PG, Kim MS, Maragakis NJ, Troncoso JC, Pandey A, Sattler R, Rothstein JD, Wang J. C9orf72 nucleotide repeat structures initiate molecular cascades of disease. Nature. 507: 195-200. PMID 24598541 DOI: 10.1038/Nature13124  0.395
2013 Donnelly CJ, Zhang PW, Pham JT, Haeusler AR, Heusler AR, Mistry NA, Vidensky S, Daley EL, Poth EM, Hoover B, Fines DM, Maragakis N, Tienari PJ, Petrucelli L, Traynor BJ, ... ... Sattler R, et al. RNA toxicity from the ALS/FTD C9ORF72 expansion is mitigated by antisense intervention. Neuron. 80: 415-28. PMID 24139042 DOI: 10.1016/J.Neuron.2013.10.015  0.491
2013 Roybon L, Lamas NJ, Garcia-Diaz A, Yang EJ, Sattler R, Jackson-Lewis V, Kim YA, Kachel CA, Rothstein JD, Przedborski S, Wichterle H, Henderson CE. Human stem cell-derived spinal cord astrocytes with defined mature or reactive phenotypes. Cell Reports. 4: 1035-48. PMID 23994478 DOI: 10.1016/J.Celrep.2013.06.021  0.302
2013 Sattler R, Tyler B, Hoover B, Coddington LT, Recinos V, Hwang L, Brem H, Rothstein JD. Increased expression of glutamate transporter GLT-1 in peritumoral tissue associated with prolonged survival and decreases in tumor growth in a rat model of experimental malignant glioma. Journal of Neurosurgery. 119: 878-86. PMID 23909244 DOI: 10.3171/2013.6.Jns122319  0.345
2013 Donnelly CJ, Zhang PW, Pham JT, Haeusler AR, Mistry NA, Vidensky S, Daley EL, Poth EM, Hoover B, Fines DM, Maragakis N, Tienari PJ, Petrucelli L, Traynor BJ, Wang J, ... ... Sattler R, et al. RNA Toxicity from the ALS/FTD C9ORF72 expansion is mitigated by antisense intervention [Neuron, 79, (September 18, 2013), 1222-1231] Neuron. 80: 1102. DOI: 10.1016/J.Neuron.2013.10.055  0.425
2011 Sattler R, Ayukawa Y, Coddington L, Sawa A, Block D, Chipkin R, Rothstein JD. Human nasal olfactory epithelium as a dynamic marker for CNS therapy development. Experimental Neurology. 232: 203-11. PMID 21945230 DOI: 10.1016/J.Expneurol.2011.09.002  0.357
2011 Adamczyk A, Gause CD, Sattler R, Vidensky S, Rothstein JD, Singer H, Wang T. Genetic and functional studies of a missense variant in a glutamate transporter, SLC1A3, in Tourette syndrome. Psychiatric Genetics. 21: 90-7. PMID 21233784 DOI: 10.1097/Ypg.0B013E328341A307  0.315
2011 Li Y, Sattler R, Yang EJ, Nunes A, Ayukawa Y, Akhtar S, Ji G, Zhang PW, Rothstein JD. Harmine, a natural beta-carboline alkaloid, upregulates astroglial glutamate transporter expression. Neuropharmacology. 60: 1168-75. PMID 21034752 DOI: 10.1016/J.Neuropharm.2010.10.016  0.396
2008 Zhou W, Zhang L, Guoxiang X, Mojsilovic-Petrovic J, Takamaya K, Sattler R, Huganir R, Kalb R. GluR1 controls dendrite growth through its binding partner, SAP97. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 10220-33. PMID 18842882 DOI: 10.1523/Jneurosci.3434-08.2008  0.494
2006 Sattler R, Rothstein JD. Regulation and dysregulation of glutamate transporters. Handbook of Experimental Pharmacology. 277-303. PMID 16722241 DOI: 10.1007/3-540-29784-7_14  0.367
2005 Kim CH, Takamiya K, Petralia RS, Sattler R, Yu S, Zhou W, Kalb R, Wenthold R, Huganir R. Persistent hippocampal CA1 LTP in mice lacking the C-terminal PDZ ligand of GluR1. Nature Neuroscience. 8: 985-7. PMID 16007085 DOI: 10.1038/Nn1432  0.681
2001 Sattler R, Tymianski M. Molecular mechanisms of glutamate receptor-mediated excitotoxic neuronal cell death. Molecular Neurobiology. 24: 107-29. PMID 11831548 DOI: 10.1385/Mn:24:1-3:107  0.38
2001 Iihara K, Joo DT, Henderson J, Sattler R, Taverna FA, Lourensen S, Orser BA, Roder JC, Tymianski M. The influence of glutamate receptor 2 expression on excitotoxicity in Glur2 null mutant mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 2224-39. PMID 11264298 DOI: 10.1523/Jneurosci.21-07-02224.2001  0.443
2001 Penzes P, Johnson RC, Sattler R, Zhang X, Huganir RL, Kambampati V, Mains RE, Eipper BA. The neuronal Rho-GEF Kalirin-7 interacts with PDZ domain-containing proteins and regulates dendritic morphogenesis. Neuron. 29: 229-42. PMID 11182094 DOI: 10.1016/S0896-6273(01)00193-3  0.661
2000 Sattler R, Tymianski M. Molecular mechanisms of calcium-dependent excitotoxicity. Journal of Molecular Medicine (Berlin, Germany). 78: 3-13. PMID 10759025 DOI: 10.1007/S001090000077  0.358
2000 Sattler R, Xiong Z, Lu WY, MacDonald JF, Tymianski M. Distinct roles of synaptic and extrasynaptic NMDA receptors in excitotoxicity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 22-33. PMID 10627577 DOI: 10.1523/Jneurosci.20-01-00022.2000  0.371
1999 Sattler R, Xiong Z, Lu WY, Hafner M, MacDonald JF, Tymianski M. Specific coupling of NMDA receptor activation to nitric oxide neurotoxicity by PSD-95 protein. Science (New York, N.Y.). 284: 1845-8. PMID 10364559 DOI: 10.1126/Science.284.5421.1845  0.377
1998 Tymianski M, Sattler R, Zabramski JM, Spetzler RF. Characterization of neuroprotection from excitotoxicity by moderate and profound hypothermia in cultured cortical neurons unmasks a temperature-insensitive component of glutamate neurotoxicity. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 18: 848-67. PMID 9701346 DOI: 10.1097/00004647-199808000-00005  0.359
1997 Sattler R, Charlton MP, Hafner M, Tymianski M. Determination of the time course and extent of neurotoxicity at defined temperatures in cultured neurons using a modified multiwell plate fluorescence scanner. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 17: 455-63. PMID 9143228 DOI: 10.1097/00004647-199704000-00011  0.345
1996 Sattler R, Tymianski M, Feyaz I, Hafner M, Tator CH. Voltage-sensitive calcium channels mediate calcium entry into cultured mammalian sympathetic neurons following neurite transection. Brain Research. 719: 239-46. PMID 8782889 DOI: 10.1016/0006-8993(96)00125-4  0.315
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