Hillary D. Protas, Ph.D. - Publications

Affiliations: 
2010 University of California, Los Angeles, Los Angeles, CA 
Area:
Radiology, Aging, Applied Mathematics

45 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Vila-Castelar C, Chen Y, Langella S, Lopera F, Zetterberg H, Hansson O, Dage JL, Janelidzde S, Su Y, Chen K, Pluim McDowell C, Martinez JE, Ramirez-Gomez L, Garcia G, Aguillon D, ... ... Protas HD, et al. Sex differences in blood biomarkers and cognitive performance in individuals with autosomal dominant Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 37279390 DOI: 10.1002/alz.13314  0.318
2023 Malek-Ahmadi M, Su Y, Ghisays V, Luo J, Devadas V, Chen Y, Lee W, Protas H, Chen K, Zetterberg H, Blennow K, Caselli RJ, Reiman EM. Plasma NfL is associated with the APOE ε4 allele, brain imaging measurements of neurodegeneration, and lower recall memory scores in cognitively unimpaired late-middle-aged and older adults. Alzheimer's Research & Therapy. 15: 74. PMID 37038190 DOI: 10.1186/s13195-023-01221-w  0.32
2023 Protas H, Ghisays V, Goradia DD, Bauer R, Devadas V, Chen K, Reiman EM, Su Y. Individualized network analysis: A novel approach to investigate tau PET using graph theory in the Alzheimer's disease continuum. Frontiers in Neuroscience. 17: 1089134. PMID 36937677 DOI: 10.3389/fnins.2023.1089134  0.372
2023 Smith GS, Protas H, Kuwabara H, Savonenko A, Nassery N, Gould NF, Kraut M, Avramopoulos D, Holt D, Dannals RF, Nandi A, Su Y, Reiman EM, Chen K. Molecular imaging of the association between serotonin degeneration and beta-amyloid deposition in mild cognitive impairment. Neuroimage. Clinical. 37: 103322. PMID 36680976 DOI: 10.1016/j.nicl.2023.103322  0.327
2022 Reiman EM, Pruzin JJ, Rios-Romenets S, Brown C, Giraldo M, Acosta-Baena N, Tobon C, Hu N, Chen Y, Ghisays V, Enos J, Goradia DD, Lee W, Luo J, Malek-Ahmadi M, ... Protas H, et al. A public resource of baseline data from the Alzheimer's Prevention Initiative Autosomal-Dominant Alzheimer's Disease Trial. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 36373344 DOI: 10.1002/alz.12843  0.312
2022 Alosco ML, Su Y, Stein TD, Protas H, Cherry JD, Adler CH, Balcer LJ, Bernick C, Pulukuri SV, Abdolmohammadi B, Coleman MJ, Palmisano JN, Tripodis Y, Mez J, Rabinovici GD, et al. Associations between near end-of-life flortaucipir PET and postmortem CTE-related tau neuropathology in six former American football players. European Journal of Nuclear Medicine and Molecular Imaging. PMID 36152064 DOI: 10.1007/s00259-022-05963-x  0.328
2022 Vila-Castelar C, Tariot PN, Sink KM, Clayton D, Langbaum JB, Thomas RG, Chen Y, Su Y, Chen K, Hu N, Giraldo-Chica M, Tobón C, Acosta-Baena N, Luna E, Londoño M, ... ... Protas HD, et al. Sex differences in cognitive resilience in preclinical autosomal-dominant Alzheimer's disease carriers and non-carriers: Baseline findings from the API ADAD Colombia Trial. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 35103388 DOI: 10.1002/alz.12552  0.331
2021 Ghisays V, Lopera F, Goradia DD, Protas HD, Malek-Ahmadi MH, Chen Y, Devadas V, Luo J, Lee W, Baena A, Bocanegra Y, Guzmán-Vélez E, Pardilla-Delgado E, Vila-Castelar C, Fox-Fuller JT, et al. PET evidence of preclinical cerebellar amyloid plaque deposition in autosomal dominant Alzheimer's disease-causing Presenilin-1 E280A mutation carriers. Neuroimage. Clinical. 31: 102749. PMID 34252876 DOI: 10.1016/j.nicl.2021.102749  0.353
2020 Quiroz YT, Zetterberg H, Reiman EM, Chen Y, Su Y, Fox-Fuller JT, Garcia G, Villegas A, Sepulveda-Falla D, Villada M, Arboleda-Velasquez JF, Guzmán-Vélez E, Vila-Castelar C, Gordon BA, Schultz SA, ... Protas HD, et al. Plasma neurofilament light chain in the presenilin 1 E280A autosomal dominant Alzheimer's disease kindred: a cross-sectional and longitudinal cohort study. The Lancet. Neurology. 19: 513-521. PMID 32470423 DOI: 10.1016/S1474-4422(20)30137-X  0.31
2020 Rios-Romenets S, Lopera F, Sink KM, Hu N, Lian Q, Guthrie H, Smith J, Cho W, Mackey H, Langbaum JB, Thomas RG, Giraldo-Chica M, Tobon C, Acosta-Baena N, Muñoz C, ... ... Protas HD, et al. Baseline demographic, clinical, and cognitive characteristics of the Alzheimer's Prevention Initiative (API) Autosomal-Dominant Alzheimer's Disease Colombia Trial. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 32418361 DOI: 10.1002/Alz.12109  0.387
2019 Ghisays V, Goradia DD, Protas H, Bauer RJ, Devadas V, Tariot PN, Lowe VJ, Knopman DS, Petersen RC, Jack CR, Caselli RJ, Su Y, Chen K, Reiman EM. Brain imaging measurements of fibrillar amyloid-β burden, paired helical filament tau burden, and atrophy in cognitively unimpaired persons with two, one, and no copies of the APOE ε4 allele. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 31831374 DOI: 10.1016/J.Jalz.2019.08.195  0.399
2019 Quiroz YT, Tariot PN, Sink K, Clayton D, Langbaum JB, Thomas RG, Giraldo M, Tobon C, Acosta-Baena N, Luna E, Londono M, Ospina P, Tirado V, Alvarez S, Chen K, ... ... Protas H, et al. F4-04-04: Association Between Cerebral Amyloidosis And Worse Cognitive Performance In Preclinical Autosomal Dominant Alzheimer'S Disease: Baseline Findings From The Api Colombia Autosomal Dominant Ad Trial Alzheimers & Dementia. 15. DOI: 10.1016/J.Jalz.2019.06.4728  0.467
2019 Su Y, Rios-Romenets S, Tariot PN, Sink K, Clayton D, Hu N, Guthrie H, Smith J, Cho W, Langbaum JB, Thomas RG, Giraldo M, Tobon C, Acosta-Baena N, Navarro A, ... ... Protas H, et al. F4-04-03: Relationships Between Baseline Brain Imaging Biomarker Measurements And Age In The Api Autosomal Dominant Alzheimer'S Disease Colombia Trial Alzheimers & Dementia. 15. DOI: 10.1016/J.Jalz.2019.06.4727  0.411
2019 Acosta-Baena N, Rios-Romenets S, Muñoz C, Bocanegra Y, Henao E, Giraldo M, Tobon C, Sink K, Hu N, Guthrie H, Smith J, Cho W, Langbaum JB, Thomas RG, Chen K, ... ... Protas H, et al. F4-04-02: Age-Related Changes In Baseline Cognitive Measures In Unimpaired Psen1 E280A Mutation Carriers And Non-Carriers In The Api Autosomal Dominant Alzheimer'S Disease Colombia Trial Alzheimers & Dementia. 15. DOI: 10.1016/J.Jalz.2019.06.4726  0.413
2019 Tariot PN, Lopera F, Sink K, Hu N, Guthrie H, Smith J, Cho W, Langbaum JB, Thomas RG, Giraldo M, Tobon C, Acosta-Baena N, Munoz C, Ospina P, Torado V, ... ... Protas H, et al. F4-04-01: Trial Design, Data Sharing Risk Mitigation, And Baseline Clinical And Cognitive Data From The Api Autosomal Dominant Alzheimer'S Disease Colombia Trial Alzheimers & Dementia. 15. DOI: 10.1016/J.Jalz.2019.06.4725  0.39
2019 Ghisays V, Goradia DD, Protas H, Bauer R, Devadas V, Tariot PN, Lowe VJ, Knopman DS, Petersen RC, Jack CR, Caselli RJ, Su Y, Chen K, Reiman EM. O3-02-02: AMYLOID PET, TAU PET, AND MRI MEASUREMENTS IN COGNITIVELY UNIMPAIRED PERSONS WITH TWO, ONE, AND NO COPIES OF THE APOE4 ALLELE Alzheimer's & Dementia. 15: P878-P878. DOI: 10.1016/J.Jalz.2019.06.4631  0.454
2019 VanGilder PS, Luo J, Goradia DD, Ghisays V, Protas H, Thiyyagura P, Malek-Ahmadi M, Lee W, Chen Y, Devadas V, Reiman EM, Su Y. P4-308: AN ADAPTIVE SAMPLING FRAMEWORK FOR PARTIAL VOLUME CORRECTION OF β-AMYLOID PET Alzheimers & Dementia. 15. DOI: 10.1016/J.Jalz.2019.06.3978  0.32
2019 Protas H, Pardilla-Delgado E, Lopera F, Johnson KA, Sperling RA, Artola A, Baena A, Bocanegra Y, Gatchel JR, Guzman-Velez E, Fuller J, Goradia DD, Thiyyagura P, VanGilder PS, Luo J, et al. Ic-P-058: Covarying Spatial Patterns Of Tau Deposition And Gray Matter Atrophy Unearthed By The Informed Multimodal Partial Least Squares (Mmpls) In Autosomal Dominant Alzheimer'S Disease: Findings From The Colbos Project Alzheimers & Dementia. 15. DOI: 10.1016/J.Jalz.2019.06.2767  0.32
2019 Protas H, Goradia DD, Ghisays V, Luo J, VanGilder PS, Thiyyagura P, Malek-Ahmadi M, Lee W, Chen Y, Devadas V, Bauer R, Landau SM, Weiner MW, Jagust WJ, Chen K, et al. Ic-P-173: Individual-Based Network Analysis: A Novel Approach To Investigate The Pathological Spread Of Phf Tau Using Graph Theory In Clinical And Preclinical Stages Of Alzheimer'S Disease Alzheimers & Dementia. 15. DOI: 10.1016/J.Jalz.2019.06.1023  0.338
2018 Ghisays V, Protas H, Chen Y, DeMarco EL, Tariot PN, Langbaum JB, Quiroz YT, Lopera F, Reiman EM, Chen K. COMPARING CEREBRAL WHITE MATTER, CEREBELLAR, AND PONTINE REFERENCE REGIONS TO CHARACTERIZE FLORBETAPIR PET MEASUREMENTS OF AMYLOID-β BURDEN IN PSEN1 E280A MUTATION CARRIERS AND NONCARRIERS FROM THE COLOMBIAN AUTOSOMAL DOMINANT ALZHEIMER’S DISEASE KINDRED Alzheimers & Dementia. 14: 20. DOI: 10.1016/J.Jalz.2018.06.2074  0.377
2017 Norton DJ, Amariglio R, Protas H, Chen K, Aguirre-Acevedo DC, Pulsifer B, Castrillon G, Tirado V, Munoz C, Tariot P, Langbaum JB, Reiman EM, Lopera F, Sperling RA, Quiroz YT. Subjective memory complaints in preclinical autosomal dominant Alzheimer disease. Neurology. PMID 28878053 DOI: 10.1212/Wnl.0000000000004533  0.316
2017 Reiman EM, Kuang X, Luo J, Chen Y, Thiyyagura P, Bauer R, Lee W, Protas H, Goradia DD, Aisen PS, Johnson K, Langbaum JB, Sperling RA, Tariot P, Jagust WJ, et al. [IC-P-041]: SAMPLE SIZES FOR 24-MONTH ALZHEIMER's PREVENTION TRIALS USING BIOMARKER ENDPOINTS IN COGNITIVELY UNIMPAIRED AMYLOID-POSITIVE ADULTS Alzheimer's & Dementia. 13: P36-P37. DOI: 10.1016/J.Jalz.2017.06.2313  0.365
2015 Quiroz YT, Schultz AP, Chen K, Protas HD, Brickhouse M, Fleisher AS, Langbaum JB, Thiyyagura P, Fagan AM, Shah AR, Muniz M, Arboleda-Velasquez JF, Munoz C, Garcia G, Acosta-Baena N, et al. Brain Imaging and Blood Biomarker Abnormalities in Children With Autosomal Dominant Alzheimer Disease: A Cross-Sectional Study. Jama Neurology. PMID 26121081 DOI: 10.1001/Jamaneurol.2015.1099  0.349
2015 Sabbagh MN, Chen K, Rogers J, Fleisher AS, Liebsack C, Bandy D, Belden C, Protas H, Thiyyagura P, Liu X, Roontiva A, Luo J, Jacobson S, Malek-Ahmadi M, Powell J, et al. Florbetapir PET, FDG PET, and MRI in Down syndrome individuals with and without Alzheimer's dementia. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 25849033 DOI: 10.1016/J.Jalz.2015.01.006  0.412
2015 Chen K, Roontiva A, Thiyyagura P, Lee W, Liu X, Ayutyanont N, Protas H, Luo JL, Bauer R, Reschke C, Bandy D, Koeppe RA, Fleisher AS, Caselli RJ, Landau S, et al. Improved power for characterizing longitudinal amyloid-β PET changes and evaluating amyloid-modifying treatments with a cerebral white matter reference region. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 56: 560-6. PMID 25745091 DOI: 10.2967/Jnumed.114.149732  0.366
2015 Quiroz YT, Protas H, Chen K, Roontiva A, Thiyyagura P, Fagan AM, Shah A, Gutierrez M, Londono M, Giraldo M, Munoz C, Tirado V, Velilla L, Garcia G, Jaimes SY, et al. Relationships between baseline biomarkers and subsequent cognitive decline in cognitively unimpaired PSEN1 E280A mutation carriers from the colombian kindred with autosomal dominant Alzheimer’s disease Alzheimers & Dementia. 11: 888. DOI: 10.1016/J.Jalz.2015.08.098  0.38
2014 Dean DC, Jerskey BA, Chen K, Protas H, Thiyyagura P, Roontiva A, O'Muircheartaigh J, Dirks H, Waskiewicz N, Lehman K, Siniard AL, Turk MN, Hua X, Madsen SK, Thompson PM, et al. Brain differences in infants at differential genetic risk for late-onset Alzheimer disease: a cross-sectional imaging study. Jama Neurology. 71: 11-22. PMID 24276092 DOI: 10.1001/Jamaneurol.2013.4544  0.375
2013 Wu X, Li J, Ayutyanont N, Protas H, Jagust W, Fleisher A, Reiman E, Yao L, Chen K. The receiver operational characteristic for binary classification with multiple indices and its application to the neuroimaging study of Alzheimer's disease. Ieee/Acm Transactions On Computational Biology and Bioinformatics / Ieee, Acm. 10: 173-80. PMID 23702553 DOI: 10.1109/Tcbb.2012.141  0.384
2013 Protas HD, Chen K, Langbaum JB, Fleisher AS, Alexander GE, Lee W, Bandy D, de Leon MJ, Mosconi L, Buckley S, Truran-Sacrey D, Schuff N, Weiner MW, Caselli RJ, Reiman EM. Posterior cingulate glucose metabolism, hippocampal glucose metabolism, and hippocampal volume in cognitively normal, late-middle-aged persons at 3 levels of genetic risk for Alzheimer disease. Jama Neurology. 70: 320-5. PMID 23599929 DOI: 10.1001/2013.Jamaneurol.286  0.354
2013 Fleisher AS, Chen K, Liu X, Ayutyanont N, Roontiva A, Thiyyagura P, Protas H, Joshi AD, Sabbagh M, Sadowsky CH, Sperling RA, Clark CM, Mintun MA, Pontecorvo MJ, Coleman RE, et al. Apolipoprotein E ε4 and age effects on florbetapir positron emission tomography in healthy aging and Alzheimer disease. Neurobiology of Aging. 34: 1-12. PMID 22633529 DOI: 10.1016/J.Neurobiolaging.2012.04.017  0.427
2013 Chen K, Stonnington C, Ayutyanont N, Reschke C, Thyyagura P, Protas H, Liu X, Roontiva A, Parks S, Bauer R, Lee W, Koeppe R, Jagust W, Foster N, Weiner M, et al. Baseline FDG-PET and volumetric MRI predicts Alzheimer's disease conversion from mild cognitive impairment: An ADNI study Alzheimers & Dementia. 9: 844. DOI: 10.1016/J.Jalz.2013.08.007  0.435
2013 Bartell J, Burns C, Thiyyagura P, Li A, Parks S, Protas H, Lee W, Fleisher A, Kaszniak A, Chen K, Reiman E. Association between higher fasting serum glucose levels and the pattern of lower regional gray matter volumes in cognitively normal adults Alzheimers & Dementia. 9: 93. DOI: 10.1016/J.Jalz.2013.05.153  0.333
2013 Protas H, Chen K, Reschke C, Roontiva A, Liu X, Parks S, Lee W, Bauer R, Ayutyanont N, Thiyyagura P, Koeppe R, Jagust W, Foster N, Weiner M, Fleisher A, et al. The pattern of cerebral hypometabolism and its association with clinical ratings in cognitively normal older adults with and without significant fibrillar amyloid burden: Findings from the Alzheimer's Disease Neuroimaging Initiative Alzheimers & Dementia. 9: 68. DOI: 10.1016/J.Jalz.2013.05.109  0.421
2013 Roontiva A, Chen K, Ayutyanont N, Protas H, Liu X, Thiyyagura P, Lee W, Reschke C, Parks S, Bauer R, Koeppe R, Jagust W, Foster N, Weiner M, Fleisher A, et al. Association between the Alzheimer's disease-related hypometabolic convergence index and clinical ratings in cognitively normal older adults with and without significant fibrillar amyloid burden: Findings from the Alzheimer's Disease Neuroimaging Initiative Alzheimers & Dementia. 9: 698. DOI: 10.1016/J.Jalz.2013.04.377  0.437
2012 Wilks MQ, Protas H, Wardak M, Kepe V, Small GW, Barrio JR, Huang SC. Automated VOI Analysis in FDDNP PET Using Structural Warping: Validation through Classification of Alzheimer's Disease Patients. International Journal of Alzheimer's Disease. 2012: 512069. PMID 22482071 DOI: 10.1155/2012/512069  0.649
2012 Protas HD, Kepe V, Hayashi KM, Klunder AD, Braskie MN, Ercoli L, Siddarth P, Bookheimer SY, Thompson PM, Small GW, Barrio JR, Huang SC. Prediction of cognitive decline based on hemispheric cortical surface maps of FDDNP PET. Neuroimage. 61: 749-60. PMID 22401755 DOI: 10.1016/J.Neuroimage.2012.02.056  0.603
2012 Langbaum JB, Chen K, Launer LJ, Fleisher AS, Lee W, Liu X, Protas HD, Reeder SA, Bandy D, Yu M, Caselli RJ, Reiman EM. Blood pressure is associated with higher brain amyloid burden and lower glucose metabolism in healthy late middle-age persons. Neurobiology of Aging. 33: 827.e11-9. PMID 21821316 DOI: 10.1016/J.Neurobiolaging.2011.06.020  0.42
2012 Protas H, Chen K, Reschke C, Roontiva A, Lee W, Nishimura M, Ayutyanont N, Liu X, Thiyyagura P, Parks S, Koeppe R, Jagust W, Foster N, Weiner M, Fleisher A, et al. Capitalizing on complementary FDG-PET and florbetapir-PET data sets to distinguish between early and late mild cognitive impairment using multimodal partial least squares Alzheimers & Dementia. 8: 20. DOI: 10.1016/J.Jalz.2012.05.056  0.441
2010 Protas HD, Huang SC, Kepe V, Hayashi K, Klunder A, Braskie MN, Ercoli L, Bookheimer S, Thompson PM, Small GW, Barrio JR. FDDNP binding using MR derived cortical surface maps. Neuroimage. 49: 240-8. PMID 19703569 DOI: 10.1016/J.Neuroimage.2009.08.035  0.587
2010 Braskie MN, Klunder AD, Hayashi KM, Protas H, Kepe V, Miller KJ, Huang SC, Barrio JR, Ercoli LM, Siddarth P, Satyamurthy N, Liu J, Toga AW, Bookheimer SY, Small GW, et al. Plaque and tangle imaging and cognition in normal aging and Alzheimer's disease. Neurobiology of Aging. 31: 1669-78. PMID 19004525 DOI: 10.1016/J.Neurobiolaging.2008.09.012  0.507
2007 Small GW, Protas HD, Huang S, Kepe V, Siddarth P, Hayashi K, Klunder A, Braskie M, Ercoli LM, Bookheimer SY, Thompson PM, Barrio JR. O2-02-05: FDDNP-PET binding values from cortical hemispheric surface maps correlate with MMSE scores Alzheimer's & Dementia. 3: S186-S186. DOI: 10.1016/J.Jalz.2007.04.039  0.345
2006 Ghisays V, Goradia DD, Protas H, Bauer R, Devadas V, Tariot PN, Lowe VJ, Knopman DS, Petersen RC, Jack CR, Caselli RJ, Chen K, Reiman EM. P4-318: PET MEASUREMENTS OF PHF TAU BURDEN IN COGNITIVELY UNIMPAIRED PERSONS WITH TWO, ONE AND NO COPIES OF THE APOE4 ALLELE Alzheimer's & Dementia. 14: P1580-P1580. DOI: 10.1016/J.Jalz.2018.07.141  0.436
2006 Protas H, Ghisays V, Luo J, DeMarco EL, Thiyyagura P, Devadas V, Bauer R, Landau SM, Weiner M, Jagust WJ, Reiman EM, Chen K. IC-P-106: FLORTAUCIPIR PAIRED HELICAL FILAMENT TAU BURDEN AND CORRELATION WITH COGNITIVE DECLINE IN MCI PATIENTS WITHOUT Aβ Alzheimer's & Dementia. 14: P91-P92. DOI: 10.1016/J.Jalz.2018.06.2172  0.377
2005 Leow A, Yu CL, Lee SJ, Huang SC, Protas H, Nicolson R, Hayashi KM, Toga AW, Thompson PM. Brain structural mapping using a novel hybrid implicit/explicit framework based on the level-set method. Neuroimage. 24: 910-27. PMID 15652325 DOI: 10.1016/J.Neuroimage.2004.09.022  0.573
2005 Protas HD, Thompson PM, Hayashi KM, Yu CL, Bergsneider M, Huang SC. Regional quantitative analysis of cortical surface maps of FDG PET images Ieee Nuclear Science Symposium Conference Record. 3: 1814-1817. DOI: 10.1109/NSSMIC.2005.1596673  0.329
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