D. Allan Butterfield, PhD, Duke University 1974 - Publications

Affiliations: 
Chemistry University of Kentucky, Lexington, KY 
Area:
http://www.researchprofiles.collexis.com/jad/expert.asp?u_id=41
Website:
http://www.chem.uky.edu/research/butterfield/

404 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Butterfield DA, Boyd-Kimball D. Mitochondrial Oxidative and Nitrosative Stress and Alzheimer Disease. Antioxidants (Basel, Switzerland). 9. PMID 32887505 DOI: 10.3390/Antiox9090818  0.64
2020 Perluigi M, Tramutola A, Pagnotta S, Barone E, Butterfield DA. The BACH1/Nrf2 Axis in Brain in Down Syndrome and Transition to Alzheimer Disease-Like Neuropathology and Dementia. Antioxidants (Basel, Switzerland). 9. PMID 32839417 DOI: 10.3390/Antiox9090779  0.32
2020 Lanzillotta C, Zuliani I, Tramutola A, Barone E, Blarzino C, Folgiero V, Caforio M, Valentini D, Villani A, Locatelli F, Butterfield DA, Head E, Perluigi M, Abisambra JF, Di Domenico F. Chronic PERK induction promotes Alzheimer-like neuropathology in Down syndrome: Insights for therapeutic intervention. Progress in Neurobiology. 101892. PMID 32795489 DOI: 10.1016/J.Pneurobio.2020.101892  0.32
2020 Tramutola A, Lanzillotta C, Di Domenico F, Head E, Butterfield DA, Perluigi M, Barone E. Brain insulin resistance triggers early onset Alzheimer disease in Down syndrome. Neurobiology of Disease. 104772. PMID 31987911 DOI: 10.1016/J.Nbd.2020.104772  0.32
2019 Lanzillotta C, Di Domenico F, Perluigi M, Butterfield DA. Targeting Mitochondria in Alzheimer Disease: Rationale and Perspectives. Cns Drugs. PMID 31410665 DOI: 10.1007/S40263-019-00658-8  0.32
2019 Di Domenico F, Tramutola A, Barone E, Lanzillotta C, Defever O, Arena A, Zuliani I, Foppoli C, Iavarone F, Vincenzoni F, Castagnola M, Butterfield DA, Perluigi M. Restoration of aberrant mTOR signaling by intranasal rapamycin reduces oxidative damage: Focus on HNE-modified proteins in a mouse model of down syndrome. Redox Biology. 101162. PMID 30876754 DOI: 10.1016/J.Redox.2019.101162  0.32
2019 Sharma N, Tramutola A, Lanzillotta C, Arena A, Blarzino C, Cassano T, Butterfield DA, Di Domenico F, Perluigi M, Barone E. Loss of biliverdin reductase-A favors Tau hyper-phosphorylation in Alzheimer's disease. Neurobiology of Disease. PMID 30738142 DOI: 10.1016/J.Nbd.2019.02.003  0.32
2019 Salameh TS, Mortell WG, Logsdon AF, Butterfield DA, Banks WA. Disruption of the hippocampal and hypothalamic blood-brain barrier in a diet-induced obese model of type II diabetes: prevention and treatment by the mitochondrial carbonic anhydrase inhibitor, topiramate. Fluids and Barriers of the Cns. 16: 1. PMID 30616618 DOI: 10.1186/S12987-018-0121-6  0.36
2019 Barone E, Sharma N, Tramutola A, Lanzillotta C, Butterfield DA, Perluigi M. P4-153: Loss Of Biliverdin Reductase-A Favors Tau Hyper-Phosphorylation In Alzheimer Disease Alzheimers & Dementia. 15: 246. DOI: 10.1016/J.Jalz.2019.06.3815  0.32
2018 Tramutola A, Lanzillotta C, Barone E, Arena A, Zuliani I, Mosca L, Blarzino C, Butterfield DA, Perluigi M, Di Domenico F. Intranasal rapamycin ameliorates Alzheimer-like cognitive decline in a mouse model of Down syndrome. Translational Neurodegeneration. 7: 28. PMID 30410750 DOI: 10.1186/S40035-018-0133-9  0.32
2018 Tramutola A, Abate G, Lanzillotta C, Triani F, Barone E, Iavarone F, Vincenzoni F, Castagnola M, Marziano M, Memo M, Garrafa E, Butterfield DA, Perluigi M, Di Domenico F, Uberti D. Protein nitration profile of CD3 lymphocytes from Alzheimer disease patients: Novel hints on immunosenescence and biomarker detection. Free Radical Biology & Medicine. 129: 430-439. PMID 30321702 DOI: 10.1016/J.Freeradbiomed.2018.10.414  0.32
2018 Butterfield DA, Boyd-Kimball D. Redox Proteomics and Amyloid β-Peptide: Insights into Alzheimer Disease. Journal of Neurochemistry. PMID 30216447 DOI: 10.1111/Jnc.14589  0.64
2018 Keeney JTR, Ren X, Warrier G, Noel T, Powell DK, Brelsfoard JM, Sultana R, Saatman KE, Clair DKS, Butterfield DA. Doxorubicin-induced elevated oxidative stress and neurochemical alterations in brain and cognitive decline: protection by MESNA and insights into mechanisms of chemotherapy-induced cognitive impairment ("chemobrain"). Oncotarget. 9: 30324-30339. PMID 30100992 DOI: 10.18632/Oncotarget.25718  0.6
2018 Barone E, Tramutola A, Triani F, Calcagnini S, Di Domenico F, Ripoli C, Gaetani S, Grassi C, Butterfield DA, Cassano T, Perluigi M. Biliverdin Reductase-A Mediates the Beneficial Effects of Intranasal Insulin in Alzheimer Disease. Molecular Neurobiology. PMID 30073505 DOI: 10.1007/S12035-018-1231-5  0.32
2018 Tramutola A, Sharma N, Barone E, Lanzillotta C, Castellani A, Iavarone F, Vincenzoni F, Castagnola M, Butterfield DA, Gaetani S, Cassano T, Perluigi M, Di Domenico F. Proteomic identification of altered protein O-GlcNAcylation in a triple transgenic mouse model of Alzheimer's disease. Biochimica Et Biophysica Acta. PMID 30031227 DOI: 10.1016/J.Bbadis.2018.07.017  0.32
2018 Butterfield DA, Boyd-Kimball D. Oxidative Stress, Amyloid-β Peptide, and Altered Key Molecular Pathways in the Pathogenesis and Progression of Alzheimer's Disease. Journal of Alzheimer's Disease : Jad. 62: 1345-1367. PMID 29562527 DOI: 10.3233/Jad-170543  0.64
2017 Butterfield DA, Perluigi M. Down Syndrome: From Development to Adult Life to Alzheimer Disease. Free Radical Biology & Medicine. PMID 29079527 DOI: 10.1016/J.Freeradbiomed.2017.10.374  0.32
2017 Di Domenico F, Tramutola A, Foppoli C, Head E, Perluigi M, Butterfield DA. mTOR IN DOWN SYNDROME: ROLE in Aß and TAU NEUROPATHOLOGY and TRANSITION to ALZHEIMER DISEASE-LIKE DEMENTIA. Free Radical Biology & Medicine. PMID 28807816 DOI: 10.1016/J.Freeradbiomed.2017.08.009  0.32
2017 Barone E, Arena A, Head E, Butterfield DA, Perluigi M. Disturbance of redox homeostasis in Down Syndrome: role of iron dysmetabolism. Free Radical Biology & Medicine. PMID 28705658 DOI: 10.1016/J.Freeradbiomed.2017.07.009  0.32
2017 Barone E, Triani F, Tramutola A, Domenico FD, Cassano T, Butterfield DA, Perluigi M. Biliverdin Reductase-A Mediates The Beneficial Effects Of Intranasal Insulin Administration On Ad Pathology In The Brain Of 3Xtg-Ad Mice Alzheimers & Dementia. 13. DOI: 10.1016/J.Jalz.2017.06.1896  0.32
2016 Swomley AM, Triplett JC, Keeney JT, Warrier G, Pearson KJ, Mattison JA, de Cabo R, Cai J, Klein JB, Butterfield DA. Comparative proteomic analyses of the parietal lobe from rhesus monkeys fed a high-fat/sugar diet with and without resveratrol supplementation, relative to a healthy diet: Insights into the roles of unhealthy diets and resveratrol on function. The Journal of Nutritional Biochemistry. 39: 169-179. PMID 27840293 DOI: 10.1016/J.Jnutbio.2016.10.006  0.52
2016 Barone E, Head E, Butterfield DA, Perluigi M. HNE-modified proteins in Down Syndrome: involvement in development of Alzheimer disease neuropathology. Free Radical Biology & Medicine. PMID 27838436 DOI: 10.1016/J.Freeradbiomed.2016.10.508  0.32
2016 Butterfield DA, Perluigi M. REDOX PROTEOMICS: A KEY TOOL FOR NEW INSIGHTS INTO PROTEIN MODIFICATION WITH RELEVANCE TO DISEASE. Antioxidants & Redox Signaling. PMID 27835924 DOI: 10.1089/Ars.2016.6919  0.32
2016 Domenico FD, Tramutola A, Butterfield DA. ROLE OF 4-HYDROXY-2-NONENAL (HNE) IN THE PATHOGENESIS OF ALZHEIMER DISEASE AND OTHER SELECTED AGE-RELATED NEURODEGENERATIVE DISORDERS. Free Radical Biology & Medicine. PMID 27789292 DOI: 10.1016/J.Freeradbiomed.2016.10.490  0.32
2016 Palmieri EM, Menga A, Lebrun A, Hooper DC, Butterfield DA, Mazzone M, Castegna A. Blockade of glutamine synthetase enhances inflammatory response in microglial cells. Antioxidants & Redox Signaling. PMID 27758118 DOI: 10.1089/Ars.2016.6715  1
2016 Tramutola A, Arena A, Cini C, Butterfield DA, Barone E. Modulation of GLP-1 signaling as a novel therapeutic approach in the treatment of Alzheimer's disease pathology. Expert Review of Neurotherapeutics. PMID 27715341 DOI: 10.1080/14737175.2017.1246183  0.32
2016 Tramutola A, Di Domenico F, Barone E, Giorgi A, Di Francesco L, Schinina E, Coccia R, Arena A, Head E, Butterfield DA, Perluigi M. Poly-Ubiquitinylation Profile in Down Syndrome Brain before and after the Development of Alzheimer Neuropathology. Antioxidants & Redox Signaling. PMID 27627691 DOI: 10.1089/ars.2016.6686  0.32
2016 Di Domenico F, Barone E, Perluigi M, Butterfield DA. The "Triangle of Death" in Alzheimer Disease Brain: The Aberrant Cross Talk Among Energy Metabolism, mTOR Signaling and Protein Homeostasis Revealed by Redox Proteomics. Antioxidants & Redox Signaling. PMID 27626216 DOI: 10.1089/ars.2016.6759  0.32
2016 Butterfield DA, Reed TT. Lipid Peroxidation and Tyrosine Nitration in Traumatic Brain Injury: Insights into Secondary Injury from Redox Proteomics. Proteomics. Clinical Applications. PMID 27588567 DOI: 10.1002/Prca.201600003  1
2016 Perluigi M, Barone E, Di Domenico F, Butterfield DA. Aberrant protein phosphorylation in alzheimer disease brain disturbs pro-survival and cell death pathways. Biochimica Et Biophysica Acta. PMID 27425034 DOI: 10.1016/j.bbadis.2016.07.005  0.32
2016 Tramutola A, Lanzillotta C, Perluigi M, Butterfield DA. Oxidative Stress, Protein Modification and Alzheimer Disease. Brain Research Bulletin. PMID 27316747 DOI: 10.1016/J.Brainresbull.2016.06.005  0.32
2016 Triplett JC, Swomley AM, Kirk J, Grimes KM, Lewis KN, Orr ME, Rodriguez KA, Cai J, Klein JB, Buffenstein R, Butterfield DA. Reaching Out to Send a Message: Proteins Associated with Neurite Outgrowth and Neurotransmission are Altered with Age in the Long-Lived Naked Mole-Rat. Neurochemical Research. PMID 26935741 DOI: 10.1007/S11064-016-1877-1  1
2016 Tramutola A, Di Domenico F, Barone E, Perluigi M, Butterfield DA. It Is All about (U)biquitin: Role of Altered Ubiquitin-Proteasome System and UCHL1 in Alzheimer Disease. Oxidative Medicine and Cellular Longevity. 2016: 2756068. PMID 26881020 DOI: 10.1155/2016/2756068  0.32
2016 Butterfield DA, Palmieri EM, Castegna A. Clinical implications from proteomic studies in neurodegenerative diseases: lessons from mitochondrial proteins. Expert Review of Proteomics. PMID 26837425 DOI: 10.1586/14789450.2016.1149470  1
2016 Zhang W, St Clair D, Butterfield DA, Vore M. Loss of Mrp1 potentiates doxorubicin-induced cytotoxicity in neonatal mouse cardiomyocytes and cardiac fibroblasts. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 26822305 DOI: 10.1093/Toxsci/Kfw021  0.32
2016 Di Domenico F, Pupo G, Giraldo E, Lloret A, Badia MC, Schinina ME, Giorgi A, Butterfield DA, Vina J, Perluigi M. Autoantibodies Profile in Matching CSF and Serum from AD and aMCI patients: Potential Pathogenic Role and Link to Oxidative Damage. Current Alzheimer Research. 13: 112-22. PMID 26679861 DOI: 10.2174/1567205013666151218131424  0.32
2016 Di Domenico F, Perluigi M, Butterfield DA. Redox Proteomics in Human Biofluids: Sample Preparation, Separation and Immunochemical Tagging for Analysis of Protein Oxidation. Methods in Molecular Biology (Clifton, N.J.). 1303: 391-403. PMID 26235080 DOI: 10.1007/978-1-4939-2627-5_23  0.32
2015 Barone E, Di Domenico F, Cassano T, Arena A, Tramutola A, Lavecchia MA, Coccia R, Butterfield DA, Perluigi M. Impairment of biliverdin reductase-A promotes brain insulin resistance in Alzheimer disease: A new paradigm. Free Radical Biology & Medicine. 91: 127-142. PMID 26698666 DOI: 10.1016/J.Freeradbiomed.2015.12.012  1
2015 Di Domenico F, Pupo G, Giraldo E, Badìa MC, Monllor P, Lloret A, Eugenia Schininà M, Giorgi A, Cini C, Tramutola A, Butterfield DA, Viña J, Perluigi M. Oxidative signature of cerebrospinal fluid from mild cognitive impairment and Alzheimer disease patients. Free Radical Biology & Medicine. 91: 1-9. PMID 26675344 DOI: 10.1016/J.Freeradbiomed.2015.12.004  0.32
2015 Triplett JC, Swomley AM, Cai J, Klein JB, Butterfield DA. Quantitative Phosphoproteomic Analyses of the Inferior Parietal Lobule from Three Different Pathological Stages of Alzheimer's Disease. Journal of Alzheimer's Disease : Jad. 49: 45-62. PMID 26444780 DOI: 10.3233/JAD-150417  1
2015 Barone E, Cenini G, Di Domenico F, Noel T, Wang C, Perluigi M, St Clair DK, Butterfield DA. Basal brain oxidative and nitrative stress levels are finely regulated by the interplay between superoxide dismutase 2 and p53. Journal of Neuroscience Research. 93: 1728-39. PMID 26251011 DOI: 10.1002/Jnr.23627  1
2015 Triplett JC, Tramutola A, Swomley A, Kirk J, Grimes K, Lewis K, Orr M, Rodriguez K, Cai J, Klein JB, Perluigi M, Buffenstein R, Butterfield DA. Age-related changes in the proteostasis network in the brain of the naked mole-rat: Implications promoting healthy longevity. Biochimica Et Biophysica Acta. 1852: 2213-24. PMID 26248058 DOI: 10.1016/J.Bbadis.2015.08.002  1
2015 Keeney JT, Miriyala S, Noel T, Moscow JA, St Clair DK, Butterfield DA. Superoxide induces protein oxidation in plasma and TNF-α elevation in macrophage culture: Insights into mechanisms of neurotoxicity following doxorubicin chemotherapy. Cancer Letters. 367: 157-61. PMID 26225838 DOI: 10.1016/J.Canlet.2015.07.023  1
2015 Butterfield DA. Redox signaling in neurodegeneration. Neurobiology of Disease. PMID 26171987 DOI: 10.1016/J.Nbd.2015.07.004  1
2015 Keeney JT, Butterfield DA. Vitamin D deficiency and Alzheimer disease: Common links. Neurobiology of Disease. PMID 26160191 DOI: 10.1016/J.Nbd.2015.06.020  1
2015 Triplett JC, Swomley A, Kirk J, Lewis K, Orr M, Rodriguez K, Cai J, Klein JB, Buffenstein R, Butterfield DA. Metabolic clues to salubrious longevity in the brain of the longest-lived rodent: the naked mole-rat. Journal of Neurochemistry. 134: 538-50. PMID 25940666 DOI: 10.1111/Jnc.13149  1
2015 Hayslip J, Dressler EV, Weiss H, Taylor TJ, Chambers M, Noel T, Miriyala S, Keeney JT, Ren X, Sultana R, Vore M, Butterfield DA, St Clair D, Moscow JA. Plasma TNF-α and Soluble TNF Receptor Levels after Doxorubicin with or without Co-Administration of Mesna-A Randomized, Cross-Over Clinical Study. Plos One. 10: e0124988. PMID 25909710 DOI: 10.1371/Journal.Pone.0124988  0.6
2015 Perluigi M, Di Domenico F, Butterfield DA. mTOR signaling in aging and neurodegeneration: At the crossroad between metabolism dysfunction and impairment of autophagy. Neurobiology of Disease. PMID 25796566 DOI: 10.1016/J.Nbd.2015.03.014  1
2015 Tramutola A, Triplett JC, Di Domenico F, Niedowicz DM, Murphy MP, Coccia R, Perluigi M, Butterfield DA. Alteration of mTOR signaling occurs early in the progression of Alzheimer disease (AD): analysis of brain from subjects with pre-clinical AD, amnestic mild cognitive impairment and late-stage AD. Journal of Neurochemistry. 133: 739-49. PMID 25645581 DOI: 10.1111/Jnc.13037  1
2015 Triplett JC, Zhang Z, Sultana R, Cai J, Klein JB, Büeler H, Butterfield DA. Quantitative expression proteomics and phosphoproteomics profile of brain from PINK1 knockout mice: insights into mechanisms of familial Parkinson's disease. Journal of Neurochemistry. 133: 750-65. PMID 25626353 DOI: 10.1111/jnc.13039  1
2015 Di Domenico F, Pupo G, Mancuso C, Barone E, Paolini F, Arena A, Blarzino C, Schmitt FA, Head E, Butterfield DA, Perluigi M. Bach1 overexpression in Down syndrome correlates with the alteration of the HO-1/BVR-a system: insights for transition to Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 44: 1107-20. PMID 25391381 DOI: 10.3233/Jad-141254  0.32
2015 Di Domenico F, Barone E, Perluigi M, Butterfield DA. Strategy to reduce free radical species in Alzheimer's disease: an update of selected antioxidants. Expert Review of Neurotherapeutics. 15: 19-40. PMID 25243342 DOI: 10.1586/14737175.2015.955853  1
2015 Swomley AM, Butterfield DA. Oxidative stress in Alzheimer disease and mild cognitive impairment: evidence from human data provided by redox proteomics Archives of Toxicology. DOI: 10.1007/s00204-015-1556-z  1
2014 Butterfield DA, Di Domenico F, Swomley AM, Head E, Perluigi M. Redox proteomics analysis to decipher the neurobiology of Alzheimer-like neurodegeneration: overlaps in Down's syndrome and Alzheimer's disease brain. The Biochemical Journal. 463: 177-89. PMID 25242166 DOI: 10.1042/Bj20140772  1
2014 Cenini G, Fiorini A, Sultana R, Perluigi M, Cai J, Klein JB, Head E, Butterfield DA. An investigation of the molecular mechanisms engaged before and after the development of Alzheimer disease neuropathology in Down syndrome: a proteomics approach. Free Radical Biology & Medicine. 76: 89-95. PMID 25151119 DOI: 10.1016/J.Freeradbiomed.2014.08.006  1
2014 Butterfield DA. The 2013 SFRBM discovery award: selected discoveries from the butterfield laboratory of oxidative stress and its sequela in brain in cognitive disorders exemplified by Alzheimer disease and chemotherapy induced cognitive impairment. Free Radical Biology & Medicine. 74: 157-74. PMID 24996204 DOI: 10.1016/J.Freeradbiomed.2014.06.006  1
2014 Butterfield DA, Di Domenico F, Barone E. Elevated risk of type 2 diabetes for development of Alzheimer disease: a key role for oxidative stress in brain. Biochimica Et Biophysica Acta. 1842: 1693-706. PMID 24949886 DOI: 10.1016/J.Bbadis.2014.06.010  1
2014 Butterfield DA, Gu L, Di Domenico F, Robinson RA. Mass spectrometry and redox proteomics: applications in disease. Mass Spectrometry Reviews. 33: 277-301. PMID 24930952 DOI: 10.1002/Mas.21374  1
2014 Förster S, Welleford AS, Triplett JC, Sultana R, Schmitz B, Butterfield DA. Increased O-GlcNAc levels correlate with decreased O-GlcNAcase levels in Alzheimer disease brain. Biochimica Et Biophysica Acta. 1842: 1333-9. PMID 24859566 DOI: 10.1016/J.Bbadis.2014.05.014  1
2014 Perluigi M, Pupo G, Tramutola A, Cini C, Coccia R, Barone E, Head E, Butterfield DA, Di Domenico F. Neuropathological role of PI3K/Akt/mTOR axis in Down syndrome brain. Biochimica Et Biophysica Acta. 1842: 1144-53. PMID 24735980 DOI: 10.1016/J.Bbadis.2014.04.007  1
2014 Di Domenico F, Pupo G, Tramutola A, Giorgi A, Schininà ME, Coccia R, Head E, Butterfield DA, Perluigi M. Redox proteomics analysis of HNE-modified proteins in Down syndrome brain: clues for understanding the development of Alzheimer disease. Free Radical Biology & Medicine. 71: 270-80. PMID 24675226 DOI: 10.1016/J.Freeradbiomed.2014.03.027  1
2014 Zhao Y, Miriyala S, Miao L, Mitov M, Schnell D, Dhar SK, Cai J, Klein JB, Sultana R, Butterfield DA, Vore M, Batinic-Haberle I, Bondada S, St Clair DK. Redox proteomic identification of HNE-bound mitochondrial proteins in cardiac tissues reveals a systemic effect on energy metabolism after doxorubicin treatment. Free Radical Biology & Medicine. 72: 55-65. PMID 24632380 DOI: 10.1016/J.Freeradbiomed.2014.03.001  1
2014 Perluigi M, Swomley AM, Butterfield DA. Redox proteomics and the dynamic molecular landscape of the aging brain. Ageing Research Reviews. 13: 75-89. PMID 24374232 DOI: 10.1016/J.Arr.2013.12.005  1
2014 Farr SA, Ripley JL, Sultana R, Zhang Z, Niehoff ML, Platt TL, Murphy MP, Morley JE, Kumar V, Butterfield DA. Antisense oligonucleotide against GSK-3β in brain of SAMP8 mice improves learning and memory and decreases oxidative stress: Involvement of transcription factor Nrf2 and implications for Alzheimer disease. Free Radical Biology & Medicine. 67: 387-95. PMID 24355211 DOI: 10.1016/J.Freeradbiomed.2013.11.014  1
2014 Hardas SS, Sultana R, Warrier G, Dan M, Wu P, Grulke EA, Tseng MT, Unrine JM, Graham UM, Yokel RA, Butterfield DA. Rat hippocampal responses up to 90 days after a single nanoceria dose extends a hierarchical oxidative stress model for nanoparticle toxicity. Nanotoxicology. 8: 155-66. PMID 24350865 DOI: 10.3109/17435390.2013.868059  1
2014 Ulatowski L, Parker R, Warrier G, Sultana R, Butterfield DA, Manor D. Vitamin E is essential for Purkinje neuron integrity. Neuroscience. 260: 120-9. PMID 24342566 DOI: 10.1016/J.Neuroscience.2013.12.001  1
2014 Butterfield DA, Dalle-Donne I. Redox proteomics: from protein modifications to cellular dysfunction and disease. Mass Spectrometry Reviews. 33: 1-6. PMID 24285334 DOI: 10.1002/Mas.21404  1
2014 Barone E, Di Domenico F, Butterfield DA. Statins more than cholesterol lowering agents in Alzheimer disease: their pleiotropic functions as potential therapeutic targets. Biochemical Pharmacology. 88: 605-16. PMID 24231510 DOI: 10.1016/J.Bcp.2013.10.030  1
2014 Tseng MT, Fu Q, Lor K, Fernandez-Botran GR, Deng ZB, Graham U, Butterfield DA, Grulke EA, Yokel RA. Persistent hepatic structural alterations following nanoceria vascular infusion in the rat. Toxicologic Pathology. 42: 984-96. PMID 24178579 DOI: 10.1177/0192623313505780  1
2014 Swomley AM, Förster S, Keeney JT, Triplett J, Zhang Z, Sultana R, Butterfield DA. Abeta, oxidative stress in Alzheimer disease: evidence based on proteomics studies. Biochimica Et Biophysica Acta. 1842: 1248-57. PMID 24120836 DOI: 10.1016/J.Bbadis.2013.09.015  1
2014 Barone E, Di Domenico F, Mancuso C, Butterfield DA. The Janus face of the heme oxygenase/biliverdin reductase system in Alzheimer disease: it's time for reconciliation. Neurobiology of Disease. 62: 144-59. PMID 24095978 DOI: 10.1016/J.Nbd.2013.09.018  1
2014 Graham UM, Tseng MT, Jasinski JB, Yokel RA, Unrine JM, Davis BH, Dozier AK, Hardas SS, Sultana R, Grulke EA, Butterfield DA. In vivo processing of ceria nanoparticles inside liver: Impact on free-radical scavenging activity and oxidative stress Chempluschem. 79: 1083-1088. DOI: 10.1002/cplu.201402080  1
2013 Hardas SS, Sultana R, Clark AM, Beckett TL, Szweda LI, Murphy MP, Butterfield DA. Oxidative modification of lipoic acid by HNE in Alzheimer disease brain. Redox Biology. 1: 80-5. PMID 24024140 DOI: 10.1016/J.Redox.2013.01.002  1
2013 Sultana R, Baglioni M, Cecchetti R, Cai J, Klein JB, Bastiani P, Ruggiero C, Mecocci P, Butterfield DA. Lymphocyte mitochondria: toward identification of peripheral biomarkers in the progression of Alzheimer disease. Free Radical Biology & Medicine. 65: 595-606. PMID 23933528 DOI: 10.1016/J.Freeradbiomed.2013.08.001  1
2013 Keeney JT, Förster S, Sultana R, Brewer LD, Latimer CS, Cai J, Klein JB, Porter NM, Butterfield DA. Dietary vitamin D deficiency in rats from middle to old age leads to elevated tyrosine nitration and proteomics changes in levels of key proteins in brain: implications for low vitamin D-dependent age-related cognitive decline. Free Radical Biology & Medicine. 65: 324-34. PMID 23872023 DOI: 10.1016/J.Freeradbiomed.2013.07.019  0.52
2013 Di Domenico F, Coccia R, Cocciolo A, Murphy MP, Cenini G, Head E, Butterfield DA, Giorgi A, Schinina ME, Mancuso C, Cini C, Perluigi M. Impairment of proteostasis network in Down syndrome prior to the development of Alzheimer's disease neuropathology: redox proteomics analysis of human brain. Biochimica Et Biophysica Acta. 1832: 1249-59. PMID 23603808 DOI: 10.1016/J.Bbadis.2013.04.013  1
2013 Butterfield DA, Swomley AM, Sultana R. Amyloid β-peptide (1-42)-induced oxidative stress in Alzheimer disease: importance in disease pathogenesis and progression. Antioxidants & Redox Signaling. 19: 823-35. PMID 23249141 DOI: 10.1089/Ars.2012.5027  1
2013 Sultana R, Perluigi M, Butterfield DA. Lipid peroxidation triggers neurodegeneration: A redox proteomics view into the Alzheimer disease brain Free Radical Biology and Medicine. 62: 157-169. PMID 23044265 DOI: 10.1016/J.Freeradbiomed.2012.09.027  1
2013 Keeney JT, Swomley AM, Förster S, Harris JL, Sultana R, Butterfield DA. Apolipoprotein A-I: insights from redox proteomics for its role in neurodegeneration. Proteomics. Clinical Applications. 7: 109-22. PMID 23027708 DOI: 10.1002/Prca.201200087  1
2013 Sultana R, Butterfield DA. Oxidative modification of brain proteins in Alzheimer's disease: perspective on future studies based on results of redox proteomics studies. Journal of Alzheimer's Disease : Jad. 33: S243-51. PMID 22683528 DOI: 10.3233/Jad-2012-129018  1
2013 Pocernich C, Butterfield DA, Head E. Diet and Brain Aging: Effects on Cell and Mitochondrial Function and Structure Bioactive Food as Dietary Interventions For the Aging Population. 249-262. DOI: 10.1016/B978-0-12-397155-5.00030-1  1
2013 Robinson RAS, Butterfield DA. Insights from proteomics into mild cognitive impairment, likely the earliest stage of alzheimer's disease Alzheimer's Disease Research Compendium. 97-116.  1
2012 Fiorini A, Sultana R, Barone E, Cenini G, Perluigi M, Mancuso C, Cai J, Klein JB, St Clair D, Butterfield DA. Lack of p53 affects the expression of several brain mitochondrial proteins: insights from proteomics into important pathways regulated by p53. Plos One. 7: e49846. PMID 23209608 DOI: 10.1371/Journal.Pone.0049846  1
2012 Cocciolo A, Di Domenico F, Coccia R, Fiorini A, Cai J, Pierce WM, Mecocci P, Butterfield DA, Perluigi M. Decreased expression and increased oxidation of plasma haptoglobin in Alzheimer disease: Insights from redox proteomics. Free Radical Biology & Medicine. 53: 1868-76. PMID 23000119 DOI: 10.1016/J.Freeradbiomed.2012.08.596  1
2012 Tsyusko OV, Hardas SS, Shoults-Wilson WA, Starnes CP, Joice G, Butterfield DA, Unrine JM. Short-term molecular-level effects of silver nanoparticle exposure on the earthworm, Eisenia fetida. Environmental Pollution (Barking, Essex : 1987). 171: 249-55. PMID 22960366 DOI: 10.1016/J.Envpol.2012.08.003  1
2012 Di Domenico F, Barone E, Mancuso C, Perluigi M, Cocciolo A, Mecocci P, Butterfield DA, Coccia R. HO-1/BVR-a system analysis in plasma from probable Alzheimer's disease and mild cognitive impairment subjects: a potential biochemical marker for the prediction of the disease. Journal of Alzheimer's Disease : Jad. 32: 277-89. PMID 22776971 DOI: 10.3233/Jad-2012-121045  1
2012 Hardas SS, Sultana R, Warrier G, Dan M, Florence RL, Wu P, Grulke EA, Tseng MT, Unrine JM, Graham UM, Yokel RA, Butterfield DA. Rat brain pro-oxidant effects of peripherally administered 5 nm ceria 30 days after exposure. Neurotoxicology. 33: 1147-55. PMID 22750192 DOI: 10.1016/J.Neuro.2012.06.007  1
2012 Erickson MA, Hartvigson PE, Morofuji Y, Owen JB, Butterfield DA, Banks WA. Lipopolysaccharide impairs amyloid β efflux from brain: altered vascular sequestration, cerebrospinal fluid reabsorption, peripheral clearance and transporter function at the blood-brain barrier. Journal of Neuroinflammation. 9: 150. PMID 22747709 DOI: 10.1186/1742-2094-9-150  1
2012 Barone E, Di Domenico F, Sultana R, Coccia R, Mancuso C, Perluigi M, Butterfield DA. Heme oxygenase-1 posttranslational modifications in the brain of subjects with Alzheimer disease and mild cognitive impairment. Free Radical Biology & Medicine. 52: 2292-301. PMID 22549002 DOI: 10.1016/J.Freeradbiomed.2012.03.020  1
2012 Sultana R, Robinson RA, Lange MB, Fiorini A, Galvan V, Fombonne J, Baker A, Gorostiza O, Zhang J, Cai J, Pierce WM, Bredesen DE, Butterfield DA. Do proteomics analyses provide insights into reduced oxidative stress in the brain of an Alzheimer disease transgenic mouse model with an M631L amyloid precursor protein substitution and thereby the importance of amyloid-beta-resident methionine 35 in Alzheimer disease pathogenesis? Antioxidants & Redox Signaling. 17: 1507-14. PMID 22500616 DOI: 10.1089/Ars.2011.4470  0.52
2012 De Marco F, Bucaj E, Foppoli C, Fiorini A, Blarzino C, Filipi K, Giorgi A, Schininà ME, Di Domenico F, Coccia R, Butterfield DA, Perluigi M. Oxidative stress in HPV-driven viral carcinogenesis: redox proteomics analysis of HPV-16 dysplastic and neoplastic tissues. Plos One. 7: e34366. PMID 22470562 DOI: 10.1371/Journal.Pone.0034366  1
2012 Butterfield DA, Keller JN. Antioxidants and antioxidant treatment in disease. Biochimica Et Biophysica Acta. 1822: 615. PMID 22414640 DOI: 10.1016/J.Bbadis.2012.02.020  1
2012 Di Domenico F, Casalena G, Jia J, Sultana R, Barone E, Cai J, Pierce WM, Cini C, Mancuso C, Perluigi M, Davis CM, Alkayed NJ, Butterfield DA, Butterfield AD. Sex differences in brain proteomes of neuron-specific STAT3-null mice after cerebral ischemia/reperfusion. Journal of Neurochemistry. 121: 680-92. PMID 22394374 DOI: 10.1111/J.1471-4159.2012.07721.X  0.52
2012 Colombo G, Dalle-Donne I, Orioli M, Giustarini D, Rossi R, Clerici M, Regazzoni L, Aldini G, Milzani A, Butterfield DA, Gagliano N. Oxidative damage in human gingival fibroblasts exposed to cigarette smoke. Free Radical Biology & Medicine. 52: 1584-96. PMID 22387198 DOI: 10.1016/J.Freeradbiomed.2012.02.030  1
2012 Tseng MT, Lu X, Duan X, Hardas SS, Sultana R, Wu P, Unrine JM, Graham U, Butterfield DA, Grulke EA, Yokel RA. Alteration of hepatic structure and oxidative stress induced by intravenous nanoceria. Toxicology and Applied Pharmacology. 260: 173-82. PMID 22373796 DOI: 10.1016/J.Taap.2012.02.008  1
2012 Yokel RA, Au TC, MacPhail R, Hardas SS, Butterfield DA, Sultana R, Goodman M, Tseng MT, Dan M, Haghnazar H, Unrine JM, Graham UM, Wu P, Grulke EA. Distribution, elimination, and biopersistence to 90 days of a systemically introduced 30 nm ceria-engineered nanomaterial in rats. Toxicological Sciences : An Official Journal of the Society of Toxicology. 127: 256-68. PMID 22367688 DOI: 10.1093/Toxsci/Kfs067  1
2012 Di Domenico F, Sultana R, Ferree A, Smith K, Barone E, Perluigi M, Coccia R, Pierce W, Cai J, Mancuso C, Squillace R, Wiengele M, Dalle-Donne I, Wolozin B, Butterfield DA. Redox proteomics analyses of the influence of co-expression of wild-type or mutated LRRK2 and Tau on C. elegans protein expression and oxidative modification: relevance to Parkinson disease. Antioxidants & Redox Signaling. 17: 1490-506. PMID 22315971 DOI: 10.1089/Ars.2011.4312  1
2012 Jungsuwadee P, Zhao T, Stolarczyk EI, Paumi CM, Butterfield DA, St Clair DK, Vore M. The G671V variant of MRP1/ABCC1 links doxorubicin-induced acute cardiac toxicity to disposition of the glutathione conjugate of 4-hydroxy-2-trans-nonenal. Pharmacogenetics and Genomics. 22: 273-84. PMID 22293538 DOI: 10.1097/Fpc.0B013E328350E270  1
2012 Buizza L, Cenini G, Lanni C, Ferrari-Toninelli G, Prandelli C, Govoni S, Buoso E, Racchi M, Barcikowska M, Styczynska M, Szybinska A, Butterfield DA, Memo M, Uberti D. Conformational altered p53 as an early marker of oxidative stress in Alzheimer's disease. Plos One. 7: e29789. PMID 22242180 DOI: 10.1371/journal.pone.0029789  1
2012 Barone E, Cenini G, Sultana R, Di Domenico F, Fiorini A, Perluigi M, Noel T, Wang C, Mancuso C, St Clair DK, Butterfield DA. Lack of p53 decreases basal oxidative stress levels in the brain through upregulation of thioredoxin-1, biliverdin reductase-A, manganese superoxide dismutase, and nuclear factor kappa-B. Antioxidants & Redox Signaling. 16: 1407-20. PMID 22229939 DOI: 10.1089/Ars.2011.4124  1
2012 Perluigi M, Butterfield DA. Oxidative Stress and Down Syndrome: A Route toward Alzheimer-Like Dementia. Current Gerontology and Geriatrics Research. 2012: 724904. PMID 22203843 DOI: 10.1155/2012/724904  1
2012 Butterfield DA, Perluigi M, Reed T, Muharib T, Hughes CP, Robinson RA, Sultana R. Redox proteomics in selected neurodegenerative disorders: from its infancy to future applications. Antioxidants & Redox Signaling. 17: 1610-55. PMID 22115501 DOI: 10.1089/Ars.2011.4109  1
2012 Perluigi M, Coccia R, Butterfield DA. 4-Hydroxy-2-nonenal, a reactive product of lipid peroxidation, and neurodegenerative diseases: a toxic combination illuminated by redox proteomics studies. Antioxidants & Redox Signaling. 17: 1590-609. PMID 22114878 DOI: 10.1089/Ars.2011.4406  0.32
2012 Evans AR, Miriyala S, St Clair DK, Butterfield DA, Robinson RA. Global effects of adriamycin treatment on mouse splenic protein levels. Journal of Proteome Research. 11: 1054-64. PMID 22112237 DOI: 10.1021/Pr200798G  1
2012 Keeney JT, Swomley AM, Harris JL, Fiorini A, Mitov MI, Perluigi M, Sultana R, Butterfield DA. Cell cycle proteins in brain in mild cognitive impairment: insights into progression to Alzheimer disease. Neurotoxicity Research. 22: 220-30. PMID 22083458 DOI: 10.1007/S12640-011-9287-2  1
2012 Pocernich CB, Butterfield DA. Elevation of glutathione as a therapeutic strategy in Alzheimer disease. Biochimica Et Biophysica Acta. 1822: 625-30. PMID 22015471 DOI: 10.1016/J.Bbadis.2011.10.003  1
2012 Cenini G, Dowling AL, Beckett TL, Barone E, Mancuso C, Murphy MP, Levine H, Lott IT, Schmitt FA, Butterfield DA, Head E. Association between frontal cortex oxidative damage and beta-amyloid as a function of age in Down syndrome. Biochimica Et Biophysica Acta. 1822: 130-8. PMID 22009041 DOI: 10.1016/J.Bbadis.2011.10.001  1
2012 Barone E, Mancuso C, Di Domenico F, Sultana R, Murphy MP, Head E, Butterfield DA. Biliverdin reductase-A: a novel drug target for atorvastatin in a dog pre-clinical model of Alzheimer disease. Journal of Neurochemistry. 120: 135-46. PMID 22004509 DOI: 10.1111/J.1471-4159.2011.07538.X  1
2012 Butterfield DA, Barone E, Di Domenico F, Cenini G, Sultana R, Murphy MP, Mancuso C, Head E. Atorvastatin treatment in a dog preclinical model of Alzheimer's disease leads to up-regulation of haem oxygenase-1 and is associated with reduced oxidative stress in brain. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 15: 981-7. PMID 21767440 DOI: 10.1017/S1461145711001118  1
2011 Butterfield DA, Sultana R. Methionine-35 of aβ(1-42): importance for oxidative stress in Alzheimer disease. Journal of Amino Acids. 2011: 198430. PMID 22312456 DOI: 10.4061/2011/198430  0.6
2011 Di Domenico F, Coccia R, Butterfield DA, Perluigi M. Circulating biomarkers of protein oxidation for Alzheimer disease: expectations within limits. Biochimica Et Biophysica Acta. 1814: 1785-95. PMID 22019699 DOI: 10.1016/J.Bbapap.2011.10.001  1
2011 Siciliano R, Barone E, Calabrese V, Rispoli V, Butterfield DA, Mancuso C. Experimental research on nitric oxide and the therapy of Alzheimer disease: a challenging bridge. Cns & Neurological Disorders Drug Targets. 10: 766-76. PMID 21999733 DOI: 10.2174/187152711798072356  1
2011 Wattamwar PP, Hardas SS, Butterfield DA, Anderson KW, Dziubla TD. Tuning of the pro-oxidant and antioxidant activity of trolox through the controlled release from biodegradable poly(trolox ester) polymers. Journal of Biomedical Materials Research. Part A. 99: 184-91. PMID 21976443 DOI: 10.1016/J.Freeradbiomed.2010.10.525  1
2011 Robinson RA, Joshi G, Huang Q, Sultana R, Baker AS, Cai J, Pierce W, St Clair DK, Markesbery WR, Butterfield DA. Proteomic analysis of brain proteins in APP/PS-1 human double mutant knock-in mice with increasing amyloid β-peptide deposition: insights into the effects of in vivo treatment with N-acetylcysteine as a potential therapeutic intervention in mild cognitive impairment and Alzheimer's disease. Proteomics. 11: 4243-56. PMID 21954051 DOI: 10.1002/Pmic.201000523  0.52
2011 Perluigi M, Butterfield DA. The identification of protein biomarkers for oxidative stress in Down syndrome. Expert Review of Proteomics. 8: 427-9. PMID 21819296 DOI: 10.1586/Epr.11.36  1
2011 Mancuso C, Siciliano R, Barone E, Butterfield DA, Preziosi P. Pharmacologists and Alzheimer disease therapy: to boldly go where no scientist has gone before. Expert Opinion On Investigational Drugs. 20: 1243-61. PMID 21810032 DOI: 10.1517/13543784.2011.601740  1
2011 Martin SB, Cenini G, Barone E, Dowling AL, Mancuso C, Butterfield DA, Murphy MP, Head E. Coenzyme Q10 and cognition in atorvastatin treated dogs. Neuroscience Letters. 501: 92-5. PMID 21763754 DOI: 10.1016/J.Neulet.2011.06.054  1
2011 Sultana R, Robinson RA, Di Domenico F, Abdul HM, St Clair DK, Markesbery WR, Cai J, Pierce WM, Butterfield DA. Proteomic identification of specifically carbonylated brain proteins in APP(NLh)/APP(NLh) × PS-1(P264L)/PS-1(P264L) human double mutant knock-in mice model of Alzheimer disease as a function of age. Journal of Proteomics. 74: 2430-40. PMID 21726674 DOI: 10.1016/J.Jprot.2011.06.015  1
2011 Pocernich CB, Lange ML, Sultana R, Butterfield DA. Nutritional approaches to modulate oxidative stress in Alzheimer's disease. Current Alzheimer Research. 8: 452-69. PMID 21605052 DOI: 10.2174/156720511796391908  1
2011 Butterfield DA, Barone E, Mancuso C. Cholesterol-independent neuroprotective and neurotoxic activities of statins: perspectives for statin use in Alzheimer disease and other age-related neurodegenerative disorders. Pharmacological Research : the Official Journal of the Italian Pharmacological Society. 64: 180-6. PMID 21536132 DOI: 10.1016/J.Phrs.2011.04.007  1
2011 Di Domenico F, Sultana R, Barone E, Perluigi M, Cini C, Mancuso C, Cai J, Pierce WM, Butterfield DA. Quantitative proteomics analysis of phosphorylated proteins in the hippocampus of Alzheimer's disease subjects. Journal of Proteomics. 74: 1091-103. PMID 21515431 DOI: 10.1016/J.Jprot.2011.03.033  1
2011 Barone E, Di Domenico F, Cenini G, Sultana R, Coccia R, Preziosi P, Perluigi M, Mancuso C, Butterfield DA. Oxidative and nitrosative modifications of biliverdin reductase-A in the brain of subjects with Alzheimer's disease and amnestic mild cognitive impairment. Journal of Alzheimer's Disease : Jad. 25: 623-33. PMID 21483094 DOI: 10.3233/Jad-2011-110092  1
2011 Aluise CD, Miriyala S, Noel T, Sultana R, Jungsuwadee P, Taylor TJ, Cai J, Pierce WM, Vore M, Moscow JA, St Clair DK, Butterfield DA. 2-Mercaptoethane sulfonate prevents doxorubicin-induced plasma protein oxidation and TNF-α release: implications for the reactive oxygen species-mediated mechanisms of chemobrain. Free Radical Biology & Medicine. 50: 1630-8. PMID 21421044 DOI: 10.1016/J.Freeradbiomed.2011.03.009  1
2011 Sultana R, Mecocci P, Mangialasche F, Cecchetti R, Baglioni M, Butterfield DA. Increased protein and lipid oxidative damage in mitochondria isolated from lymphocytes from patients with Alzheimer's disease: insights into the role of oxidative stress in Alzheimer's disease and initial investigations into a potential biomarker for this dementing disorder. Journal of Alzheimer's Disease : Jad. 24: 77-84. PMID 21383494 DOI: 10.3233/Jad-2011-101425  1
2011 Perluigi M, di Domenico F, Fiorini A, Cocciolo A, Giorgi A, Foppoli C, Butterfield DA, Giorlandino M, Giorlandino C, Schininà ME, Coccia R. Oxidative stress occurs early in Down syndrome pregnancy: A redox proteomics analysis of amniotic fluid. Proteomics. Clinical Applications. 5: 167-78. PMID 21360684 DOI: 10.1002/Prca.201000121  1
2011 Butterfield DA, Owen JB. Lectin-affinity chromatography brain glycoproteomics and Alzheimer disease: insights into protein alterations consistent with the pathology and progression of this dementing disorder. Proteomics. Clinical Applications. 5: 50-6. PMID 21280237 DOI: 10.1002/Prca.201000070  1
2011 Barone E, Di Domenico F, Cenini G, Sultana R, Cini C, Preziosi P, Perluigi M, Mancuso C, Butterfield DA. Biliverdin reductase--a protein levels and activity in the brains of subjects with Alzheimer disease and mild cognitive impairment. Biochimica Et Biophysica Acta. 1812: 480-7. PMID 21241799 DOI: 10.1016/J.Bbadis.2011.01.005  1
2011 Robinson RA, Lange MB, Sultana R, Galvan V, Fombonne J, Gorostiza O, Zhang J, Warrier G, Cai J, Pierce WM, Bredesen DE, Butterfield DA. Differential expression and redox proteomics analyses of an Alzheimer disease transgenic mouse model: effects of the amyloid-β peptide of amyloid precursor protein. Neuroscience. 177: 207-22. PMID 21223993 DOI: 10.1016/J.Neuroscience.2011.01.005  1
2011 Barone E, Cenini G, Di Domenico F, Martin S, Sultana R, Mancuso C, Murphy MP, Head E, Butterfield DA. Long-term high-dose atorvastatin decreases brain oxidative and nitrosative stress in a preclinical model of Alzheimer disease: a novel mechanism of action. Pharmacological Research : the Official Journal of the Italian Pharmacological Society. 63: 172-80. PMID 21193043 DOI: 10.1016/J.Phrs.2010.12.007  1
2011 Butterfield DA. Atorvastatin and Aβ(1-40): not as simple as cholesterol reduction in brain and relevance to Alzheimer disease. Experimental Neurology. 228: 15-8. PMID 21192930 DOI: 10.1016/J.Expneurol.2010.12.014  1
2011 Sultana R, Butterfield DA. Identification of the oxidative stress proteome in the brain. Free Radical Biology & Medicine. 50: 487-94. PMID 21111808 DOI: 10.1016/J.Freeradbiomed.2010.11.021  1
2011 Butterfield DA, Reed T, Sultana R. Roles of 3-nitrotyrosine- and 4-hydroxynonenal-modified brain proteins in the progression and pathogenesis of Alzheimer's disease. Free Radical Research. 45: 59-72. PMID 20942567 DOI: 10.3109/10715762.2010.520014  1
2011 Aluise CD, Robinson RA, Cai J, Pierce WM, Markesbery WR, Butterfield DA. Redox proteomics analysis of brains from subjects with amnestic mild cognitive impairment compared to brains from subjects with preclinical Alzheimer's disease: insights into memory loss in MCI. Journal of Alzheimer's Disease : Jad. 23: 257-69. PMID 20930294 DOI: 10.3233/Jad-2010-101083  1
2011 Butterfield DA. Preface for the special issue of neuromolecular medicine in memory of the life and legacy of William R. Markesbery, M.D. Neuromolecular Medicine. 13: 1-2. PMID 20625940 DOI: 10.1007/S12017-010-8129-3  1
2011 Butterfield DA. Oxidative stress in Alzheimer disease: synergy between the Butterfield and Markesbery laboratories. Neuromolecular Medicine. 13: 19-22. PMID 20596797 DOI: 10.1007/S12017-010-8123-9  1
2011 Sowell RA, Butterfield DA. Spontaneous vertebrate models of Alzheimer dementia: Selectively bred strains (SAM strains) Neuromethods. 48: 271-293. DOI: 10.1007/978-1-60761-898-0_15  1
2011 Sowell RA, Butterfield DA. Insights from proteomics into mild cognitive impairment, likely the earliest stage of Alzheimer's disease Alzheimer's Disease Research Journal. 3: 95-114.  1
2010 Di Domenico F, Perluigi M, Butterfield DA, Cornelius C, Calabrese V. Oxidative damage in rat brain during aging: interplay between energy and metabolic key target proteins. Neurochemical Research. 35: 2184-92. PMID 20963486 DOI: 10.1007/s11064-010-0295-z  1
2010 Sultana R, Di Domenico F, Tseng M, Cai J, Noel T, Chelvarajan RL, Pierce WD, Cini C, Bondada S, St Clair DK, Butterfield DA. Doxorubicin-induced thymus senescence. Journal of Proteome Research. 9: 6232-41. PMID 20945937 DOI: 10.1021/Pr100465M  1
2010 Di Domenico F, Owen JB, Sultana R, Sowell RA, Perluigi M, Cini C, Cai J, Pierce WM, Butterfield DA. The wheat germ agglutinin-fractionated proteome of subjects with Alzheimer's disease and mild cognitive impairment hippocampus and inferior parietal lobule: Implications for disease pathogenesis and progression. Journal of Neuroscience Research. 88: 3566-77. PMID 20936705 DOI: 10.1002/Jnr.22528  1
2010 Perluigi M, Di Domenico F, Giorgi A, Schininà ME, Coccia R, Cini C, Bellia F, Cambria MT, Cornelius C, Butterfield DA, Calabrese V. Redox proteomics in aging rat brain: involvement of mitochondrial reduced glutathione status and mitochondrial protein oxidation in the aging process. Journal of Neuroscience Research. 88: 3498-507. PMID 20936692 DOI: 10.1002/jnr.22500  1
2010 Di Domenico F, Casalena G, Sultana R, Cai J, Pierce WM, Perluigi M, Cini C, Baracca A, Solaini G, Lenaz G, Jia J, Dziennis S, Murphy SJ, Alkayed NJ, Butterfield DA. Involvement of Stat3 in mouse brain development and sexual dimorphism: a proteomics approach. Brain Research. 1362: 1-12. PMID 20875800 DOI: 10.1016/J.Brainres.2010.09.074  1
2010 Owen JB, Sultana R, Aluise CD, Erickson MA, Price TO, Bu G, Banks WA, Butterfield DA. Oxidative modification to LDL receptor-related protein 1 in hippocampus from subjects with Alzheimer disease: implications for Aβ accumulation in AD brain. Free Radical Biology & Medicine. 49: 1798-803. PMID 20869432 DOI: 10.1016/J.Freeradbiomed.2010.09.013  1
2010 Haskew-Layton RE, Payappilly JB, Smirnova NA, Ma TC, Chan KK, Murphy TH, Guo H, Langley B, Sultana R, Butterfield DA, Santagata S, Alldred MJ, Gazaryan IG, Bell GW, Ginsberg SD, et al. Controlled enzymatic production of astrocytic hydrogen peroxide protects neurons from oxidative stress via an Nrf2-independent pathway. Proceedings of the National Academy of Sciences of the United States of America. 107: 17385-90. PMID 20855618 DOI: 10.1073/Pnas.1003996107  1
2010 Aluise CD, Sultana R, Tangpong J, Vore M, St Clair D, Moscow JA, Butterfield DA. Chemo brain (chemo fog) as a potential side effect of doxorubicin administration: role of cytokine-induced, oxidative/nitrosative stress in cognitive dysfunction. Advances in Experimental Medicine and Biology. 678: 147-56. PMID 20738017 DOI: 10.1007/978-1-4419-6306-2_19  1
2010 Owen JB, Butterfield DA. Measurement of oxidized/reduced glutathione ratio. Methods in Molecular Biology (Clifton, N.J.). 648: 269-77. PMID 20700719 DOI: 10.1007/978-1-60761-756-3_18  1
2010 Huang Q, Aluise CD, Joshi G, Sultana R, St Clair DK, Markesbery WR, Butterfield DA. Potential in vivo amelioration by N-acetyl-L-cysteine of oxidative stress in brain in human double mutant APP/PS-1 knock-in mice: toward therapeutic modulation of mild cognitive impairment. Journal of Neuroscience Research. 88: 2618-29. PMID 20648652 DOI: 10.1002/Jnr.22422  1
2010 Hardas SS, Butterfield DA, Sultana R, Tseng MT, Dan M, Florence RL, Unrine JM, Graham UM, Wu P, Grulke EA, Yokel RA. Brain distribution and toxicological evaluation of a systemically delivered engineered nanoscale ceria. Toxicological Sciences : An Official Journal of the Society of Toxicology. 116: 562-76. PMID 20457660 DOI: 10.1093/Toxsci/Kfq137  1
2010 Aluise CD, Robinson RA, Beckett TL, Murphy MP, Cai J, Pierce WM, Markesbery WR, Butterfield DA. Preclinical Alzheimer disease: brain oxidative stress, Abeta peptide and proteomics. Neurobiology of Disease. 39: 221-8. PMID 20399861 DOI: 10.1016/J.Nbd.2010.04.011  1
2010 Butterfield DA. William R. Markesbery, M.D.: A legacy of excellence in Alzheimer's disease research and a life well-lived. Journal of Alzheimer's Disease : Jad. 20: 3-4. PMID 20378955 DOI: 10.3233/Jad-2010-100246  1
2010 Di Domenico F, Sultana R, Tiu GF, Scheff NN, Perluigi M, Cini C, Butterfield DA. Protein levels of heat shock proteins 27, 32, 60, 70, 90 and thioredoxin-1 in amnestic mild cognitive impairment: an investigation on the role of cellular stress response in the progression of Alzheimer disease. Brain Research. 1333: 72-81. PMID 20362559 DOI: 10.1016/J.Brainres.2010.03.085  1
2010 Butterfield DA, Bader Lange ML, Sultana R. Involvements of the lipid peroxidation product, HNE, in the pathogenesis and progression of Alzheimer's disease. Biochimica Et Biophysica Acta. 1801: 924-9. PMID 20176130 DOI: 10.1016/J.Bbalip.2010.02.005  1
2010 Butterfield DA, Hardas SS, Lange ML. Oxidatively modified glyceraldehyde-3-phosphate dehydrogenase (GAPDH) and Alzheimer's disease: many pathways to neurodegeneration. Journal of Alzheimer's Disease : Jad. 20: 369-93. PMID 20164570 DOI: 10.3233/Jad-2010-1375  1
2010 Joshi G, Aluise CD, Cole MP, Sultana R, Pierce WM, Vore M, St Clair DK, Butterfield DA. Alterations in brain antioxidant enzymes and redox proteomic identification of oxidized brain proteins induced by the anti-cancer drug adriamycin: implications for oxidative stress-mediated chemobrain. Neuroscience. 166: 796-807. PMID 20096337 DOI: 10.1016/J.Neuroscience.2010.01.021  1
2010 Bader Lange ML, St Clair D, Markesbery WR, Studzinski CM, Murphy MP, Butterfield DA. Age-related loss of phospholipid asymmetry in APP(NLh)/APP(NLh) x PS-1(P264L)/PS-1(P264L) human double mutant knock-in mice: relevance to Alzheimer disease. Neurobiology of Disease. 38: 104-15. PMID 20083199 DOI: 10.1016/J.Nbd.2010.01.004  1
2010 Cenini G, MacCarinelli G, Lanni C, Bonini SA, Ferrari-Toninelli G, Govoni S, Racchi M, Butterfield DA, Memo M, Uberti D. Wild type but not mutant APP is involved in protective adaptive responses against oxidants Amino Acids. 39: 271-283. PMID 20063202 DOI: 10.1007/s00726-009-0438-1  1
2010 Sultana R, Butterfield DA. Role of oxidative stress in the progression of Alzheimer's disease Journal of Alzheimer's Disease. 19: 341-353. PMID 20061649 DOI: 10.3233/Jad-2010-1222  1
2010 Calabrese V, Cornelius C, Mancuso C, Lentile R, Stella AMG, Butterfield DA. Redox homeostasis and cellular stress response in aging and neurodegeneration Methods in Molecular Biology (Clifton, N.J.). 610: 285-308. PMID 20013185 DOI: 10.1007/978-1-60327-029-8_17  1
2010 Butterfield DA, Galvan V, Lange MB, Tang H, Sowell RA, Spilman P, Fombonne J, Gorostiza O, Zhang J, Sultana R, Bredesen DE. In vivo oxidative stress in brain of Alzheimer disease transgenic mice: Requirement for methionine 35 in amyloid β-peptide of APP Free Radical Biology and Medicine. 48: 136-144. PMID 19854267 DOI: 10.1016/J.Freeradbiomed.2009.10.035  1
2010 Sultana R, Banks WA, Butterfield DA. Decreased levels of PSD95 and two associated proteins and increased levels of BCl2 and caspase 3 in hippocampus from subjects with amnestic mild cognitive impairment: Insights into their potential roles for loss of synapses and memory, accumulation of Aβ, and neurodegeneration in a prodromal stage of Alzheimer's disease Journal of Neuroscience Research. 88: 469-477. PMID 19774677 DOI: 10.1002/Jnr.22227  1
2010 Suzuki YJ, Carini M, Butterfield DA. Protein carbonylation. Antioxidants & Redox Signaling. 12: 323-5. PMID 19743917 DOI: 10.1089/ars.2009.2887  1
2010 Sultana R, Perluigi M, Newman SF, Pierce WM, Cini C, Coccia R, Butterfield DA. Redox proteomic analysis of carbonylated brain proteins in mild cognitive impairment and early Alzheimer's disease. Antioxidants & Redox Signaling. 12: 327-36. PMID 19686046 DOI: 10.1089/Ars.2009.2810  1
2010 Perluigi M, Di Domenico F, Blarzino C, Foppoli C, Cini C, Giorgi A, Grillo C, De Marco F, Butterfield DA, Schininà ME, Coccia R. Effects of UVB-induced oxidative stress on protein expression and specific protein oxidation in normal human epithelial keratinocytes: A proteomic approach Proteome Science. 8. DOI: 10.1186/1477-5956-8-13  1
2010 Butterfield DA, Opii WO. Mitochondrial Dysfunction in Nervous System Injury Encyclopedia of Neuroscience. 887-894. DOI: 10.1016/B978-008045046-9.00506-4  1
2009 Perluigi M, Sultana R, Cenini G, Di Domenico F, Memo M, Pierce WM, Coccia R, Butterfield DA. Redox proteomics identification of 4-hydroxynonenal-modified brain proteins in Alzheimer's disease: Role of lipid peroxidation in Alzheimer's disease pathogenesis. Proteomics. Clinical Applications. 3: 682-693. PMID 20333275 DOI: 10.1002/Prca.200800161  0.6
2009 Butterfield DA, Lange MLB. Multifunctional roles of enolase in Alzheimer's disease brain: Beyond altered glucose metabolism Journal of Neurochemistry. 111: 915-933. PMID 19780894 DOI: 10.1111/J.1471-4159.2009.06397.X  1
2009 Sultana R, Butterfield DA. Oxidatively modified, mitochondria-relevant brain proteins in subjects with Alzheimer disease and mild cognitive impairment Journal of Bioenergetics and Biomembranes. 41: 441-446. PMID 19777328 DOI: 10.1007/S10863-009-9241-7  1
2009 Calabrese V, Cornelius C, Rizzarelli E, Owen JB, Dinkova-Kostova AT, Butterfield DA. Nitric oxide in cell survival: A Janus molecule Antioxidants and Redox Signaling. 11: 2717-2739. PMID 19558211 DOI: 10.1089/Ars.2009.2721  1
2009 Sultana R, Perluigi M, Butterfield DA. Proteomics identification of oxidatively modified proteins in brain Methods in Molecular Biology (Clifton, N.J.). 564: 291-301. PMID 19544029 DOI: 10.1007/978-1-60761-157-8_16  1
2009 Sultana R, Reed T, Butterfield DA. Detection of 4-hydroxy-2-nonenal- and 3-nitrotyrosine-modified proteins using a proteomics approach. Methods in Molecular Biology (Clifton, N.J.). 519: 351-61. PMID 19381594 DOI: 10.1007/978-1-59745-281-6_22  1
2009 Reed TT, Pierce WM, Markesbery WR, Butterfield DA. Proteomic identification of HNE-bound proteins in early Alzheimer disease: Insights into the role of lipid peroxidation in the progression of AD. Brain Research. 1274: 66-76. PMID 19374891 DOI: 10.1016/J.Brainres.2009.04.009  1
2009 Aluise CD, St Clair D, Vore M, Butterfield DA. In vivo amelioration of adriamycin induced oxidative stress in plasma by gamma-glutamylcysteine ethyl ester (GCEE). Cancer Letters. 282: 25-9. PMID 19342159 DOI: 10.1016/J.Canlet.2009.02.047  1
2009 Sultana R, Perluigi M, Butterfield DA. Oxidatively modified proteins in Alzheimer's disease (AD), mild cognitive impairment and animal models of AD: Role of Abeta in pathogenesis Acta Neuropathologica. 118: 131-150. PMID 19288120 DOI: 10.1007/S00401-009-0517-0  1
2009 Di Domenico F, Perluigi M, Foppoli C, Blarzino C, Coccia R, De Marco F, Butterfield DA, Cini C. Protective effect of ferulic acid ethyl ester against oxidative stress mediated by UVB irradiation in human epidermal melanocytes Free Radical Research. 43: 365-375. PMID 19274591 DOI: 10.1080/10715760902777329  1
2009 Perluigi M, Giorgi A, Blarzino C, De Marco F, Foppoli C, Di Domenico F, Butterfield DA, Schininà ME, Cini C, Coccia R. Proteomics analysis of protein expression and specific protein oxidation in human papillomavirus transformed keratinocytes upon UVB irradiation Journal of Cellular and Molecular Medicine. 13: 1809-1822. PMID 19267883 DOI: 10.1111/J.1582-4934.2008.00465.X  1
2009 Jungsuwadee P, Nithipongvanitch R, Chen Y, Oberley TD, Butterfield DA, St Clair DK, Vore M. Mrp1 localization and function in cardiac mitochondria after doxorubicin Molecular Pharmacology. 75: 1117-1126. PMID 19233900 DOI: 10.1124/Mol.108.052209  1
2009 Di Domenico F, Cenini G, Sultana R, Perluigi M, Uberti D, Memo M, Butterfield DA. Glutathionylation of the pro-apoptotic protein p53 in alzheimer's disease brain: Implications for AD pathogenesis Neurochemical Research. 34: 727-733. PMID 19199029 DOI: 10.1007/S11064-009-9924-9  1
2009 Ribeiro LR, Fighera MR, Oliveira MS, Furian AF, Rambo LM, Ferreira AP, Saraiva AL, Souza MA, Lima FD, Magni DV, Dezengrini R, Flores EF, Butterfield DA, Ferreira J, dos Santos AR, et al. Methylmalonate-induced seizures are attenuated in inducible nitric oxide synthase knockout mice. International Journal of Developmental Neuroscience : the Official Journal of the International Society For Developmental Neuroscience. 27: 157-63. PMID 19073247 DOI: 10.1016/J.Ijdevneu.2008.11.005  1
2009 Owen JB, Domenico FD, Suitana R, Perluigi M, Cini C, Pierce WM, Butterfield DA. Proteomics-determined differences in the concanavalin-A-fractionated proteome of hippocampus and inferior parietal lobule in subjects with alzheimer's disease and mild cognitive impairment: Implications for progression of AD Journal of Proteome Research. 8: 471-482. PMID 19072283 DOI: 10.1021/Pr800667A  1
2009 Reed TT, Owen J, Pierce WM, Sebastian A, Sullivan PG, Butterfield DA. Proteomic identification of nitrated brain proteins in traumatic brain-injured rats treated postinjury with gamma-glutamylcysteine ethyl ester: insights into the role of elevation of glutathione as a potential therapeutic strategy for traumatic brain injury. Journal of Neuroscience Research. 87: 408-17. PMID 18803298 DOI: 10.1002/Jnr.21872  1
2009 Reed TT, Pierce WM, Turner DM, Markesbery WR, Butterfield DA. Proteomic identification of nitrated brain proteins in early Alzheimer's disease inferior parietal lobule. Journal of Cellular and Molecular Medicine. 13: 2019-29. PMID 18752637 DOI: 10.1111/J.1582-4934.2008.00478.X  0.36
2009 Ansari MA, Abdul HM, Joshi G, Opii WO, Butterfield DA. Protective effect of quercetin in primary neurons against Aβ(1-42): relevance to Alzheimer's disease Journal of Nutritional Biochemistry. 20: 269-275. PMID 18602817 DOI: 10.1016/J.Jnutbio.2008.03.002  1
2009 Yokel RA, Florence RL, Unrine JM, Tseng MT, Graham UM, Wu P, Grulke EA, Sultana R, Hardas SS, Butterfield DA. Biodistribution and oxidative stress effects of a systemically-introduced commercial ceria engineered nanomaterial Nanotoxicology. 3: 234-248. DOI: 10.1080/17435390902974496  1
2009 Domenico FD, Cenini G, Sultana R, Perluigi M, Uberti D, Memo M, Butterfield DA. Erratum: Glutathionylation of the pro-apoptotic protein p53 in alzheimer's disease brain: Implications for AD pathogenesis (Neurochemical Research (2009) 34 (727-733) DOI 10.1007/s11064-009-9924-9 Neurochemical Research. 34. DOI: 10.1007/S11064-009-9955-2  0.6
2009 Sultana R, Butterfield DA. Proteomics identification of carbonylated and HNE-bound brain proteins in Alzheimer's disease Methods in Molecular Biology. 566: 123-135. DOI: 10.1007/978-1-59745-562-6_9  1
2009 Perluigi M, Sultana R, Cenini G, Di Domenico F, Memo M, Pierce WM, Coccia R, Butterfield DA. Redox proteomics identification of 4-hydroxynonenalmodified brain proteins in Alzheimer's disease: Role of lipid peroxidation in Alzheimer's disease pathogenesis Proteomics - Clinical Applications. 3: 682-693. DOI: 10.1002/prca.200800161  1
2008 Sultana R, Newman SF, Huang Q, Butterfield DA. Detection of carbonylated proteins in two-dimensional sodium dodecyl sulfate polyacrylamide gel electrophoresis separations. Methods in Molecular Biology (Clifton, N.J.). 476: 153-63. PMID 19157015 DOI: 10.1007/978-1-59745-129-1_11  1
2008 Owen JB, Opii WO, Ramassamy C, Pierce WM, Butterfield DA. Proteomic analysis of brain protein expression levels in NF-κβ p50 -/- homozygous knockout mice Brain Research. 1240: 22-30. PMID 18817763 DOI: 10.1016/J.Brainres.2008.09.001  1
2008 Abdul HM, Sultana R, St Clair DK, Markesbery WR, Butterfield DA. Oxidative damage in brain from human mutant APP/PS-1 double knock-in mice as a function of age. Free Radical Biology & Medicine. 45: 1420-5. PMID 18762245 DOI: 10.1016/J.Freeradbiomed.2008.08.012  1
2008 Aluise CD, Sowell RA, Butterfield DA. Peptides and proteins in plasma and cerebrospinal fluid as biomarkers for the prediction, diagnosis, and monitoring of therapeutic efficacy of Alzheimer's disease. Biochimica Et Biophysica Acta. 1782: 549-58. PMID 18760351 DOI: 10.1016/J.Bbadis.2008.07.008  1
2008 Cenini G, Sultana R, Memo M, Butterfield DA. Elevated levels of pro-apoptotic p53 and its oxidative modification by the lipid peroxidation product, HNE,in brain from subjects with amnestic mild cognitive impairment and Alzheimer's disease Journal of Cellular and Molecular Medicine. 12: 987-994. PMID 18494939 DOI: 10.1111/J.1582-4934.2008.00163.X  1
2008 Butterfield DA, Sultana R. Redox proteomics: Understanding oxidative stress in the progression of age-related neurodegenerative disorders Expert Review of Proteomics. 5: 157-160. PMID 18466047 DOI: 10.1586/14789450.5.2.157  1
2008 Oesterling E, Chopra N, Gavalas V, Arzuaga X, Lim EJ, Sultana R, Butterfield DA, Bachas L, Hennig B. Alumina nanoparticles induce expression of endothelial cell adhesion molecules. Toxicology Letters. 178: 160-6. PMID 18456438 DOI: 10.1016/J.Toxlet.2008.03.011  1
2008 Cenini G, Sultana R, Memo M, Butterfield DA. Effects of oxidative and nitrosative stress in brain on p53 proapoptotic protein in amnestic mild cognitive impairment and Alzheimer disease Free Radical Biology and Medicine. 45: 81-85. PMID 18439434 DOI: 10.1016/J.Freeradbiomed.2008.03.015  1
2008 Sultana R, Butterfield DA. Slot-Blot Analysis of 3-Nitrotyrosine-Modified Brain Proteins Methods in Enzymology. 440: 309-316. PMID 18423227 DOI: 10.1016/S0076-6879(07)00820-8  1
2008 Butterfield DA, Sultana R. Identification of 3-Nitrotyosine-Modified Brain Proteins by Redox Proteomics Methods in Enzymology. 440: 295-308. PMID 18423226 DOI: 10.1016/S0076-6879(07)00819-1  1
2008 Reed T, Perluigi M, Sultana R, Pierce WM, Klein JB, Turner DM, Coccia R, Markesbery WR, Butterfield DA. Redox proteomic identification of 4-hydroxy-2-nonenal-modified brain proteins in amnestic mild cognitive impairment: insight into the role of lipid peroxidation in the progression and pathogenesis of Alzheimer's disease. Neurobiology of Disease. 30: 107-20. PMID 18325775 DOI: 10.1016/J.Nbd.2007.12.007  1
2008 Sultana R, Piroddi M, Galli F, Butterfield DA. Protein levels and activity of some antioxidant enzymes in hippocampus of subjects with amnestic mild cognitive impairment Neurochemical Research. 33: 2540-2546. PMID 18320305 DOI: 10.1007/S11064-008-9593-0  1
2008 Farr SA, Yamada KA, Butterfield DA, Abdul HM, Xu L, Miller NE, Banks WA, Morley JE. Obesity and hypertriglyceridemia produce cognitive impairment. Endocrinology. 149: 2628-36. PMID 18276751 DOI: 10.1210/En.2007-1722  1
2008 Bader Lange ML, Cenini G, Piroddi M, Abdul HM, Sultana R, Galli F, Memo M, Butterfield DA. Loss of phospholipid asymmetry and elevated brain apoptotic protein levels in subjects with amnestic mild cognitive impairment and Alzheimer disease. Neurobiology of Disease. 29: 456-64. PMID 18077176 DOI: 10.1016/J.Nbd.2007.11.004  1
2008 Opii WO, Joshi G, Head E, Milgram NW, Muggenburg BA, Klein JB, Pierce WM, Cotman CW, Butterfield DA. Proteomic identification of brain proteins in the canine model of human aging following a long-term treatment with antioxidants and a program of behavioral enrichment: relevance to Alzheimer's disease. Neurobiology of Aging. 29: 51-70. PMID 17055614 DOI: 10.1016/J.Neurobiolaging.2006.09.012  1
2008 Mecocci P, Mariani E, Polidori MC, Hensley K, Butterfield DA. Antioxidant agents in Alzheimer's disease Central Nervous System Agents in Medicinal Chemistry. 8: 48-63. DOI: 10.2174/187152408783790613  1
2008 Butterfield DA. An overview of biofunctional membranes for tunable separations, metal-ion capture, and enzyme catalysis based on research from the laboratories of Allan Butterfield and Dibakar Bhattacharyya Separation Science and Technology. 43: 3942-3954. DOI: 10.1080/01496390802414551  1
2008 Sultana R, Butterfield DA. Redox proteomics studies of in vivo amyloid beta-peptide animal models of Alzheimer's disease: Insight into the role of oxidative stress Proteomics - Clinical Applications. 2: 685-696. DOI: 10.1002/Prca.200780024  1
2008 Sultana R, Reed T, Butterfield DA. Redox Proteomics and Metabolic Proteins in Brain of Subjects with Alzheimer's Disease, Mild Cognitive Impairment, and Models Thereof Neural Degeneration and Repair: Gene Expression Profiling, Proteomics and Systems Biology. 181-207. DOI: 10.1002/9783527622467.ch9  1
2007 Sultana R, Butterfield DA. Alterations of some membrane transport proteins in Alzheimer's disease: Role of amyloid β-peptide Molecular Biosystems. 4: 36-41. PMID 18075672 DOI: 10.1039/B715278G  1
2007 Mancuso C, Bates TE, Butterfield DA, Calafato S, Cornelius C, De Lorenzo A, Dinkova Kostova AT, Calabrese V. Natural antioxidants in Alzheimer's disease. Expert Opinion On Investigational Drugs. 16: 1921-31. PMID 18042001 DOI: 10.1517/13543784.16.12.1921  1
2007 Calabrese V, Mancuso C, Calvani M, Rizzarelli E, Butterfield DA, Giuffrida Stella AM. Nitric oxide in the central nervous system: Neuroprotection versus neurotoxicity Nature Reviews Neuroscience. 8: 766-775. PMID 17882254 DOI: 10.1038/Nrn2214  1
2007 Butterfield DA, Sultana R. Redox proteomics identification of oxidatively modified brain proteins in Alzheimer's disease and mild cognitive impairment: Insights into the progression of this dementing disorder Journal of Alzheimer's Disease. 12: 61-72. PMID 17851195 DOI: 10.3233/Jad-2007-12107  1
2007 Sultana R, Reed T, Perluigi M, Coccia R, Pierce WM, Butterfield DA. Proteomic identification of nitrated brain proteins in amnestic mild cognitive impairment: a regional study. Journal of Cellular and Molecular Medicine. 11: 839-51. PMID 17760844 DOI: 10.1111/J.1582-4934.2007.00065.X  1
2007 Butterfield DA, Reed T, Newman SF, Sultana R. Roles of amyloid beta-peptide-associated oxidative stress and brain protein modifications in the pathogenesis of Alzheimer's disease and mild cognitive impairment. Free Radical Biology & Medicine. 43: 658-77. PMID 17664130 DOI: 10.1016/J.Freeradbiomed.2007.05.037  1
2007 Mello CF, Sultana R, Piroddi M, Cai J, Pierce WM, Klein JB, Butterfield DA. Acrolein induces selective protein carbonylation in synaptosomes. Neuroscience. 147: 674-9. PMID 17570602 DOI: 10.1016/J.Neuroscience.2007.04.003  1
2007 Sultana R, Boyd-Kimball D, Cai J, Pierce WM, Klein JB, Merchant M, Butterfield DA. Proteomics analysis of the Alzheimer's disease hippocampal proteome. Journal of Alzheimer's Disease : Jad. 11: 153-64. PMID 17522440 DOI: 10.3233/Jad-2007-11203  1
2007 Opii WO, Nukala VN, Sultana R, Pandya JD, Day KM, Merchant ML, Klein JB, Sullivan PG, Butterfield DA. Proteomic identification of oxidized mitochondrial proteins following experimental traumatic brain injury. Journal of Neurotrauma. 24: 772-89. PMID 17518533 DOI: 10.1089/Neu.2006.0229  1
2007 Butterfield DA, Reed TT, Perluigi M, De Marco C, Coccia R, Keller JN, Markesbery WR, Sultana R. Elevated levels of 3-nitrotyrosine in brain from subjects with amnestic mild cognitive impairment: implications for the role of nitration in the progression of Alzheimer's disease. Brain Research. 1148: 243-8. PMID 17395167 DOI: 10.1016/J.Brainres.2007.02.084  1
2007 Newman SF, Sultana R, Perluigi M, Coccia R, Cai J, Pierce WM, Klein JB, Turner DM, Butterfield DA. An increase in S-glutathionylated proteins in the Alzheimer's disease inferior parietal lobule, a proteomics approach. Journal of Neuroscience Research. 85: 1506-14. PMID 17387692 DOI: 10.1002/Jnr.21275  1
2007 Mello CF, Rubin MA, Sultana R, Barron S, Littleton JM, Butterfield DA. Difluoromethylornithine decreases long-lasting protein oxidation induced by neonatal ethanol exposure in the hippocampus of adolescent rats. Alcoholism, Clinical and Experimental Research. 31: 887-94. PMID 17386069 DOI: 10.1111/J.1530-0277.2007.00369.X  1
2007 Tangpong J, Cole MP, Sultana R, Estus S, Vore M, St Clair W, Ratanachaiyavong S, St Clair DK, Butterfield DA. Adriamycin-mediated nitration of manganese superoxide dismutase in the central nervous system: insight into the mechanism of chemobrain. Journal of Neurochemistry. 100: 191-201. PMID 17227439 DOI: 10.1111/J.1471-4159.2006.04179.X  1
2007 Joshi G, Hardas S, Sultana R, St. Clair DK, Vore M, Butterfield DA. Glutathione elevation by γ-glutamyl cysteine ethyl ester as a potential therapeutic strategy for preventing oxidative stress in brain mediated by in vivo administration of adriamycin: Implication for chemobrain Journal of Neuroscience Research. 85: 497-503. PMID 17171703 DOI: 10.1002/Jnr.21158  1
2007 Vaishnav RA, Getchell ML, Poon HF, Barnett KR, Hunter SA, Pierce WM, Klein JB, Butterfield DA, Getchell TV. Oxidative stress in the aging murine olfactory bulb: redox proteomics and cellular localization. Journal of Neuroscience Research. 85: 373-85. PMID 17131389 DOI: 10.1002/Jnr.21130  1
2007 Mancuso C, Scapagnini G, Currò D, Giuffrida Stella AM, De Marco C, Butterfield DA, Calabrese V. Mitochondrial dysfunction, free radical generation and cellular stress response in neurodegenerative disorders Frontiers in Bioscience. 12: 1107-1123. PMID 17127365 DOI: 10.2741/2130  1
2007 Opii WO, Sultana R, Abdul HM, Ansari MA, Nath A, Butterfield DA. Oxidative stress and toxicity induced by the nucleoside reverse transcriptase inhibitor (NRTI)--2',3'-dideoxycytidine (ddC): relevance to HIV-dementia. Experimental Neurology. 204: 29-38. PMID 17069802 DOI: 10.1016/J.Expneurol.2006.09.010  0.6
2007 Sultana R, Butterfield DA. Regional expression of key cell cycle proteins in brain from subjects with amnestic mild cognitive impairment Neurochemical Research. 32: 655-662. PMID 17006763 DOI: 10.1007/S11064-006-9123-X  1
2006 Butterfield DA, Gnjec A, Poon HF, Castegna A, Pierce WM, Klein JB, Martins RN. Redox proteomics identification of oxidatively modified brain proteins in inherited Alzheimer's disease: an initial assessment. Journal of Alzheimer's Disease : Jad. 10: 391-7. PMID 17183150 DOI: 10.3233/Jad-2006-10407  1
2006 Ansari MA, Joshi G, Huang Q, Opii WO, Abdul HM, Sultana R, Butterfield DA. In vivo administration of D609 leads to protection of subsequently isolated gerbil brain mitochondria subjected to in vitro oxidative stress induced by amyloid beta-peptide and other oxidative stressors: relevance to Alzheimer's disease and other oxidative stress-related neurodegenerative disorders. Free Radical Biology & Medicine. 41: 1694-703. PMID 17145558 DOI: 10.1016/J.Freeradbiomed.2006.09.002  0.6
2006 Jungsuwadee P, Cole MP, Sultana R, Joshi G, Tangpong J, Butterfield DA, St Clair DK, Vore M. Increase in Mrp1 expression and 4-hydroxy-2-nonenal adduction in heart tissue of Adriamycin-treated C57BL/6 mice. Molecular Cancer Therapeutics. 5: 2851-60. PMID 17121932 DOI: 10.1158/1535-7163.Mct-06-0297  0.6
2006 Smuleac V, Butterfield DA, Bhattacharyya D. Layer-by-layer-assembled microfiltration membranes for biomolecule immobilization and enzymatic catalysis. Langmuir : the Acs Journal of Surfaces and Colloids. 22: 10118-24. PMID 17107008 DOI: 10.1021/La061124D  1
2006 Steiner J, Haughey N, Li W, Venkatesan A, Anderson C, Reid R, Malpica T, Pocernich C, Butterfield DA, Nath A. Oxidative stress and therapeutic approaches in HIV dementia. Antioxidants & Redox Signaling. 8: 2089-100. PMID 17034352 DOI: 10.1089/Ars.2006.8.2089  1
2006 Sultana R, Perluigi M, Butterfield DA. Protein oxidation and lipid peroxidation in brain of subjects with Alzheimer's disease: Insights into mechanism of neurodegeneration from redox proteomics Antioxidants and Redox Signaling. 8: 2021-2037. PMID 17034347 DOI: 10.1089/Ars.2006.8.2021  1
2006 Calabrese V, Sultana R, Scapagnini G, Guagliano E, Sapienza M, Bella R, Kanski J, Pennisi G, Mancuso C, Stella AM, Butterfield DA. Nitrosative stress, cellular stress response, and thiol homeostasis in patients with Alzheimer's disease. Antioxidants & Redox Signaling. 8: 1975-86. PMID 17034343 DOI: 10.1089/Ars.2006.8.1975  1
2006 Chen Y, Daosukho C, Opii WO, Turner DM, Pierce WM, Klein JB, Vore M, Butterfield DA, St Clair DK. Redox proteomic identification of oxidized cardiac proteins in adriamycin-treated mice. Free Radical Biology & Medicine. 41: 1470-7. PMID 17023274 DOI: 10.1016/J.Freeradbiomed.2006.08.006  1
2006 Butterfield DA, Abdul HM, Opii W, Newman SF, Joshi G, Ansari MA, Sultana R. Pin1 in Alzheimer's disease. Journal of Neurochemistry. 98: 1697-706. PMID 16945100 DOI: 10.1111/J.1471-4159.2006.03995.X  1
2006 Butterfield DA, Perluigi M, Sultana R. Oxidative stress in Alzheimer's disease brain: New insights from redox proteomics European Journal of Pharmacology. 545: 39-50. PMID 16860790 DOI: 10.1016/J.Ejphar.2006.06.026  1
2006 Butterfield DA, Abdul HM, Newman S, Reed T. Redox proteomics in some age-related neurodegenerative disorders or models thereof. Neurorx : the Journal of the American Society For Experimental Neurotherapeutics. 3: 344-57. PMID 16815218 DOI: 10.1016/J.Nurx.2006.05.003  1
2006 Langer AK, Poon HF, Münch G, Lynn BC, Arendt T, Butterfield DA. Identification of AGE-modified proteins in SH-SY5Y and OLN-93 cells. Neurotoxicity Research. 9: 255-68. PMID 16782585 DOI: 10.1007/Bf03033316  1
2006 Tangpong J, Cole MP, Sultana R, Joshi G, Estus S, Vore M, St Clair W, Ratanachaiyavong S, St Clair DK, Butterfield DA. Adriamycin-induced, TNF-alpha-mediated central nervous system toxicity. Neurobiology of Disease. 23: 127-39. PMID 16697651 DOI: 10.1016/J.Nbd.2006.02.013  1
2006 Calabrese V, Butterfield DA, Scapagnini G, Stella AMG, Maines MD. Redox regulation of heat shock protein expression by signaling involving nitric oxide and carbon monoxide: Relevance to brain aging, neurodegenerative disorders, and longevity Antioxidants and Redox Signaling. 8: 444-477. PMID 16677090 DOI: 10.1089/Ars.2006.8.444  1
2006 Calabrese V, Colombrita C, Sultana R, Scapagnini G, Calvani M, Butterfield DA, Giuffrida Stella AM. Redox modulation of heat shock protein expression by acetylcarnitine in aging brain: Relationship to antioxidant status and mitochondrial function Antioxidants and Redox Signaling. 8: 404-416. PMID 16677087 DOI: 10.1089/ars.2006.8.404  1
2006 Poon HF, Calabrese V, Calvani M, Butterfield DA. Proteomics analyses of specific protein oxidation and protein expression in aged rat brain and its modulation by l-acetylcarnitine: Insights into the mechanisms of action of this proposed therapeutic agent for CNS disorders associated with oxidative stress Antioxidants and Redox Signaling. 8: 381-394. PMID 16677085 DOI: 10.1089/Ars.2006.8.381  1
2006 Chinta SJ, Rajagopalan S, Butterfield DA, Andersen JK. In vitro and in vivo neuroprotection by gamma-glutamylcysteine ethyl ester against MPTP: relevance to the role of glutathione in Parkinson's disease. Neuroscience Letters. 402: 137-41. PMID 16644116 DOI: 10.1016/J.Neulet.2006.03.056  1
2006 Perluigi M, Joshi G, Sultana R, Calabrese V, De Marco C, Coccia R, Cini C, Butterfield DA. In vivo protective effects of ferulic acid ethyl ester against amyloid-beta peptide 1-42-induced oxidative stress Journal of Neuroscience Research. 84: 418-426. PMID 16634068 DOI: 10.1002/Jnr.20879  1
2006 Abdul HM, Calabrese V, Calvani M, Butterfield DA. Acetyl-L-carnitine-induced up-regulation of heat shock proteins protects cortical neurons against amyloid-beta peptide 1-42-mediated oxidative stress and neurotoxicity: implications for Alzheimer's disease. Journal of Neuroscience Research. 84: 398-408. PMID 16634066 DOI: 10.1002/Jnr.20877  1
2006 Sultana R, Newman SF, Abdul HM, Cai J, Pierce WM, Klein JB, Merchant M, Butterfield DA. Protective effect of D609 against amyloid-beta1-42-induced oxidative modification of neuronal proteins: redox proteomics study. Journal of Neuroscience Research. 84: 409-17. PMID 16634065 DOI: 10.1002/Jnr.20876  1
2006 Mohmmad Abdul H, Sultana R, Keller JN, St Clair DK, Markesbery WR, Butterfield DA. Mutations in amyloid precursor protein and presenilin-1 genes increase the basal oxidative stress in murine neuronal cells and lead to increased sensitivity to oxidative stress mediated by amyloid beta-peptide (1-42), HO and kainic acid: implications for Alzheimer's disease. Journal of Neurochemistry. 96: 1322-35. PMID 16478525 DOI: 10.1111/J.1471-4159.2005.03647.X  1
2006 Butterfield DA, Poon HF, St Clair D, Keller JN, Pierce WM, Klein JB, Markesbery WR. Redox proteomics identification of oxidatively modified hippocampal proteins in mild cognitive impairment: insights into the development of Alzheimer's disease. Neurobiology of Disease. 22: 223-32. PMID 16466929 DOI: 10.1016/J.Nbd.2005.11.002  1
2006 Perluigi M, Joshi G, Sultana R, Calabrese V, De Marco C, Coccia R, Butterfield DA. In vivo protection by the xanthate tricyclodecan-9-yl-xanthogenate against amyloid β-peptide (1-42)-induced oxidative stress Neuroscience. 138: 1161-1170. PMID 16427207 DOI: 10.1016/j.neuroscience.2005.12.004  1
2006 Butterfield DA, Reed T, Perluigi M, De Marco C, Coccia R, Cini C, Sultana R. Elevated protein-bound levels of the lipid peroxidation product, 4-hydroxy-2-nonenal, in brain from persons with mild cognitive impairment. Neuroscience Letters. 397: 170-3. PMID 16413966 DOI: 10.1016/J.Neulet.2005.12.017  1
2006 Calabrese V, Stella AMG, Calvani M, Butterfield DA. Acetylcarnitine and cellular stress response: Roles in nutritional redox homeostasis and regulation of longevity genes Journal of Nutritional Biochemistry. 17: 73-88. PMID 16413418 DOI: 10.1016/J.Jnutbio.2005.03.027  1
2006 Bartov O, Sultana R, Butterfield DA, Atlas D. Low molecular weight thiol amides attenuate MAPK activity and protect primary neurons from Abeta(1-42) toxicity. Brain Research. 1069: 198-206. PMID 16386719 DOI: 10.1016/J.Brainres.2005.10.079  0.6
2006 Joshi G, Perluigi M, Sultana R, Agrippino R, Calabrese V, Butterfield DA. In vivo protection of synaptosomes by ferulic acid ethyl ester (FAEE) from oxidative stress mediated by 2,2-azobis(2-amidino-propane)dihydrochloride (AAPH) or Fe2+/H2O2: Insight into mechanisms of neuroprotection and relevance to oxidative stress-related neurodegenerative disorders Neurochemistry International. 48: 318-327. PMID 16386335 DOI: 10.1016/J.Neuint.2005.11.006  1
2006 Sultana R, Poon HF, Cai J, Pierce WM, Merchant M, Klein JB, Markesbery WR, Butterfield DA. Identification of nitrated proteins in Alzheimer's disease brain using a redox proteomics approach. Neurobiology of Disease. 22: 76-87. PMID 16378731 DOI: 10.1016/J.Nbd.2005.10.004  1
2006 Sultana R, Boyd-Kimball D, Poon HF, Cai J, Pierce WM, Klein JB, Merchant M, Markesbery WR, Butterfield DA. Redox proteomics identification of oxidized proteins in Alzheimer's disease hippocampus and cerebellum: an approach to understand pathological and biochemical alterations in AD. Neurobiology of Aging. 27: 1564-76. PMID 16271804 DOI: 10.1016/J.Neurobiolaging.2005.09.021  1
2006 Sultana R, Perluigi M, Butterfield DA. Redox proteomics identification of oxidatively modified proteins in Alzheimer's disease brain and in vivo and in vitro models of AD centered around Aβ(1-42) Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences. 833: 3-11. PMID 16236561 DOI: 10.1016/J.Jchromb.2005.09.024  1
2006 Boyd-Kimball D, Poon HF, Lynn BC, Cai J, Pierce WM, Klein JB, Ferguson J, Link CD, Butterfield DA. Proteomic identification of proteins specifically oxidized in Caenorhabditis elegans expressing human Abeta(1-42): implications for Alzheimer's disease. Neurobiology of Aging. 27: 1239-49. PMID 16099075 DOI: 10.1016/J.Neurobiolaging.2005.07.001  1
2006 Poon HF, Shepherd HM, Reed TT, Calabrese V, Stella AM, Pennisi G, Cai J, Pierce WM, Klein JB, Butterfield DA. Proteomics analysis provides insight into caloric restriction mediated oxidation and expression of brain proteins associated with age-related impaired cellular processes: Mitochondrial dysfunction, glutamate dysregulation and impaired protein synthesis. Neurobiology of Aging. 27: 1020-34. PMID 15996793 DOI: 10.1016/J.Neurobiolaging.2005.05.014  1
2006 Poon HF, Vaishnav RA, Getchell TV, Getchell ML, Butterfield DA. Quantitative proteomics analysis of differential protein expression and oxidative modification of specific proteins in the brains of old mice. Neurobiology of Aging. 27: 1010-9. PMID 15979213 DOI: 10.1016/J.Neurobiolaging.2005.05.006  1
2006 Sultana R, Boyd-Kimball D, Poon HF, Cai J, Pierce WM, Klein JB, Markesbery WR, Zhou XZ, Lu KP, Butterfield DA. Oxidative modification and down-regulation of Pin1 in Alzheimer's disease hippocampus: A redox proteomics analysis. Neurobiology of Aging. 27: 918-25. PMID 15950321 DOI: 10.1016/J.Neurobiolaging.2005.05.005  1
2006 Ranjan D, Chen C, Johnston TD, Jeon H, Ibrahim M, Drake J, Butterfield DA. Stimulation of Epstein-Barr virus-infected human B cell growth by physiological concentrations of 4-hydroxynonenal Cell Biochemistry and Function. 24: 147-152. PMID 15651079 DOI: 10.1002/Cbf.1201  1
2006 Butterfield DA, Sultana R, Poon HF. Redox Proteomics: A New Approach to Investigate Oxidative Stress in Alzheimer's Disease Redox Proteomics: From Protein Modifications to Cellular Dysfunction and Diseases. 563-603. DOI: 10.1002/0471973122.ch18  1
2005 Joshi G, Sultana R, Tangpong J, Cole MP, St Clair DK, Vore M, Estus S, Butterfield DA. Free radical mediated oxidative stress and toxic side effects in brain induced by the anti cancer drug adriamycin: insight into chemobrain. Free Radical Research. 39: 1147-54. PMID 16298740 DOI: 10.1080/10715760500143478  1
2005 Poon HF, Hensley K, Thongboonkerd V, Merchant ML, Lynn BC, Pierce WM, Klein JB, Calabrese V, Butterfield DA. Redox proteomics analysis of oxidatively modified proteins in G93A-SOD1 transgenic mice--a model of familial amyotrophic lateral sclerosis. Free Radical Biology & Medicine. 39: 453-62. PMID 16043017 DOI: 10.1016/J.Freeradbiomed.2005.03.030  1
2005 Butterfield DA, Poon HF. The senescence-accelerated prone mouse (SAMP8): A model of age-related cognitive decline with relevance to alterations of the gene expression and protein abnormalities in Alzheimer's disease Experimental Gerontology. 40: 774-783. PMID 16026957 DOI: 10.1016/J.Exger.2005.05.007  1
2005 Poon HF, Vaishnav RA, Butterfield DA, Getchell ML, Getchell TV. Proteomic identification of differentially expressed proteins in the aging murine olfactory system and transcriptional analysis of the associated genes. Journal of Neurochemistry. 94: 380-92. PMID 15998289 DOI: 10.1111/J.1471-4159.2005.03215.X  1
2005 Perluigi M, Poon HF, Maragos W, Pierce WM, Klein JB, Calabrese V, Cini C, De Marco C, Butterfield DA. Proteomic analysis of protein expression and oxidative modification in r6/2 transgenic mice: a model of Huntington disease. Molecular & Cellular Proteomics : McP. 4: 1849-61. PMID 15968004 DOI: 10.1074/Mcp.M500090-Mcp200  1
2005 Poon HF, Farr SA, Banks WA, Pierce WM, Klein JB, Morley JE, Butterfield DA. Proteomic identification of less oxidized brain proteins in aged senescence-accelerated mice following administration of antisense oligonucleotide directed at the Abeta region of amyloid precursor protein. Brain Research. Molecular Brain Research. 138: 8-16. PMID 15932783 DOI: 10.1016/J.Molbrainres.2005.02.020  1
2005 Calabrese V, Lodi R, Tonon C, D'Agata V, Sapienza M, Scapagnini G, Mangiameli A, Pennisi G, Stella AMG, Butterfield DA. Oxidative stress, mitochondrial dysfunction and cellular stress response in Friedreich's ataxia Journal of the Neurological Sciences. 233: 145-162. PMID 15896810 DOI: 10.1016/J.Jns.2005.03.012  1
2005 Pocernich CB, Sultana R, Mohmmad-Abdul H, Nath A, Butterfield DA. HIV-dementia, Tat-induced oxidative stress, and antioxidant therapeutic considerations. Brain Research. Brain Research Reviews. 50: 14-26. PMID 15890409 DOI: 10.1016/J.Brainresrev.2005.04.002  1
2005 Boyd-Kimball D, Castegna A, Sultana R, Poon HF, Petroze R, Lynn BC, Klein JB, Butterfield DA. Proteomic identification of proteins oxidized by Abeta(1-42) in synaptosomes: implications for Alzheimer's disease. Brain Research. 1044: 206-15. PMID 15885219 DOI: 10.1016/J.Brainres.2005.02.086  1
2005 Keller JN, Schmitt FA, Scheff SW, Ding Q, Chen Q, Butterfield DA, Markesbery WR. Evidence of increased oxidative damage in subjects with mild cognitive impairment. Neurology. 64: 1152-6. PMID 15824339 DOI: 10.1212/01.Wnl.0000156156.13641.Ba  1
2005 Boyd-Kimball D, Sultana R, Poon HF, Lynn BC, Casamenti F, Pepeu G, Klein JB, Butterfield DA. Proteomic identification of proteins specifically oxidized by intracerebral injection of amyloid beta-peptide (1-42) into rat brain: implications for Alzheimer's disease. Neuroscience. 132: 313-24. PMID 15802185 DOI: 10.1016/J.Neuroscience.2004.12.022  1
2005 Joshi G, Sultana R, Perluigi M, Butterfield DA. In vivo protection of synaptosomes from oxidative stress mediated by Fe2+/H2O2 or 2,2-azobis-(2-amidinopropane) dihydrochloride by the glutathione mimetic tricyclodecan-9-yl-xanthogenate Free Radical Biology and Medicine. 38: 1023-1031. PMID 15780760 DOI: 10.1016/J.Freeradbiomed.2004.12.027  0.6
2005 Poon HF, Frasier M, Shreve N, Calabrese V, Wolozin B, Butterfield DA. Mitochondrial associated metabolic proteins are selectively oxidized in A30P alpha-synuclein transgenic mice--a model of familial Parkinson's disease. Neurobiology of Disease. 18: 492-8. PMID 15755676 DOI: 10.1016/J.Nbd.2004.12.009  1
2005 Boyd-Kimball D, Sultana R, Mohmmad-Abdul H, Butterfield DA. Neurotoxicity and oxidative stress in D1M-substituted Alzheimer's Aβ(1-42): relevance to N-terminal methionine chemistry in small model peptides Peptides. 26: 665-673. PMID 15752582 DOI: 10.1016/J.Peptides.2004.11.001  0.64
2005 Perluigi M, Fai Poon H, Hensley K, Pierce WM, Klein JB, Calabrese V, De Marco C, Butterfield DA. Proteomic analysis of 4-hydroxy-2-nonenal-modified proteins in G93A-SOD1 transgenic mice--a model of familial amyotrophic lateral sclerosis. Free Radical Biology & Medicine. 38: 960-8. PMID 15749392 DOI: 10.1016/J.Freeradbiomed.2004.12.021  1
2005 Pocernich CB, Boyd-Kimball D, Poon HF, Thongboonkerd V, Lynn BC, Klein JB, Calebrese V, Nath A, Butterfield DA. Proteomics analysis of human astrocytes expressing the HIV protein Tat. Brain Research. Molecular Brain Research. 133: 307-16. PMID 15710248 DOI: 10.1016/J.Molbrainres.2004.10.023  1
2005 Pocernich CB, Poon HF, Boyd-Kimball D, Lynn BC, Nath A, Klein JB, Butterfield DA. Proteomic analysis of oxidatively modified proteins induced by the mitochondrial toxin 3-nitropropionic acid in human astrocytes expressing the HIV protein tat. Brain Research. Molecular Brain Research. 133: 299-306. PMID 15710247 DOI: 10.1016/J.Molbrainres.2004.10.024  1
2005 Sultana R, Ravagna A, Mohmmad-Abdul H, Calabrese V, Butterfield DA. Ferulic acid ethyl ester protects neurons against amyloid β-peptide(1-42)-induced oxidative stress and neurotoxicity: Relationship to antioxidant activity Journal of Neurochemistry. 92: 749-758. PMID 15686476 DOI: 10.1111/J.1471-4159.2004.02899.X  1
2005 Boyd-Kimball D, Sultana R, Abdul HM, Butterfield DA. Gamma-glutamylcysteine ethyl ester-induced up-regulation of glutathione protects neurons against Abeta(1-42)-mediated oxidative stress and neurotoxicity: implications for Alzheimer's disease. Journal of Neuroscience Research. 79: 700-6. PMID 15678514 DOI: 10.1002/Jnr.20394  0.64
2005 Boyd-Kimball D, Sultana R, Poon HF, Mohmmad-Abdul H, Lynn BC, Klein JB, Butterfield DA. Gamma-glutamylcysteine ethyl ester protection of proteins from Abeta(1-42)-mediated oxidative stress in neuronal cell culture: a proteomics approach. Journal of Neuroscience Research. 79: 707-13. PMID 15672443 DOI: 10.1002/Jnr.20393  1
2005 Calabrese V, Ravagna A, Colombrita C, Scapagnini G, Guagliano E, Calvani M, Butterfield DA, Giuffrida Stella AM. Acetylcarnitine induces heme oxygenase in rat astrocytes and protects against oxidative stress: Involvement of the transcription factor Nrf2 Journal of Neuroscience Research. 79: 509-521. PMID 15641110 DOI: 10.1002/Jnr.20386  1
2005 Poon HF, Farr SA, Thongboonkerd V, Lynn BC, Banks WA, Morley JE, Klein JB, Butterfield DA. Proteomic analysis of specific brain proteins in aged SAMP8 mice treated with alpha-lipoic acid: implications for aging and age-related neurodegenerative disorders. Neurochemistry International. 46: 159-68. PMID 15627516 DOI: 10.1016/J.Neuint.2004.07.008  1
2004 Sultana R, Butterfield DA. Oxidatively modified GST and MRP1 in Alzheimer's disease brain: Implications for accumulation of reactive lipid peroxidation products Neurochemical Research. 29: 2215-2220. PMID 15672542 DOI: 10.1007/S11064-004-7028-0  1
2004 Boyd-Kimball D, Abdul HM, Reed T, Sultana R, Butterfield DA. Role of phenylalanine 20 in Alzheimer's amyloid β-peptide (1-42)-induced oxidative stress and neurotoxicity Chemical Research in Toxicology. 17: 1743-1749. PMID 15606152 DOI: 10.1021/Tx049796W  1
2004 Calabrese V, Calvani M, Butterfield DA. Increased formation of short-chain organic acids after chronic ethanol administration and its interaction with the carnitine pool in rat Archives of Biochemistry and Biophysics. 431: 271-278. PMID 15488476 DOI: 10.1016/J.Abb.2004.08.020  1
2004 Antony JM, van Marle G, Opii W, Butterfield DA, Mallet F, Yong VW, Wallace JL, Deacon RM, Warren K, Power C. Human endogenous retrovirus glycoprotein-mediated induction of redox reactants causes oligodendrocyte death and demyelination. Nature Neuroscience. 7: 1088-95. PMID 15452578 DOI: 10.1038/Nn1319  1
2004 Mohmmad Abdul H, Wenk GL, Gramling M, Hauss-Wegrzyniak B, Butterfield DA. APP and PS-1 mutations induce brain oxidative stress independent of dietary cholesterol: implications for Alzheimer's disease. Neuroscience Letters. 368: 148-50. PMID 15351438 DOI: 10.1016/J.Neulet.2004.06.077  1
2004 Calabrese V, Giuffrida Stella AM, Butterfield DA, Scapagnini G. Redox regulation in neurodegeneration and longevity: Role of the heme oxygenase and HSP70 systems in brain stress tolerance Antioxidants and Redox Signaling. 6: 895-913. PMID 15345150 DOI: 10.1089/Ars.2004.6.895  1
2004 Scapagnini G, Butterfield DA, Colombrita C, Sultana R, Pascale A, Calabrese V. Ethyl ferulate, a lipophilic polyphenol, induces HO-1 and protects rat neurons against oxidative stress Antioxidants and Redox Signaling. 6: 811-818. PMID 15345140 DOI: 10.1089/Ars.2004.6.811  1
2004 Sultana R, Newman S, Mohmmad-Abdul H, Keller JN, Butterfield DA. Protective effect of the xanthate, D609, on Alzheimer's amyloid β-peptide (1-42)-induced oxidative stress in primary neuronal cells Free Radical Research. 38: 449-458. PMID 15293552 DOI: 10.1080/1071576042000206478  1
2004 Pocernich CB, Sultana R, Hone E, Turchan J, Martins RN, Calabrese V, Nath A, Butterfield DA. Effects of apolipoprotein E on the human immunodeficiency virus protein Tat in neuronal cultures and synaptosomes. Journal of Neuroscience Research. 77: 532-9. PMID 15264223 DOI: 10.1002/Jnr.20182  1
2004 Poon HF, Joshi G, Sultana R, Farr SA, Banks WA, Morley JE, Calabrese V, Butterfield DA. Antisense directed at the Aβ region of APP decreases brain oxidative markers in aged senescence accelerated mice Brain Research. 1018: 86-96. PMID 15262209 DOI: 10.1016/J.Brainres.2004.05.048  1
2004 Poon HF, Castegna A, Farr SA, Thongboonkerd V, Lynn BC, Banks WA, Morley JE, Klein JB, Butterfield DA. Quantitative proteomics analysis of specific protein expression and oxidative modification in aged senescence-accelerated-prone 8 mice brain. Neuroscience. 126: 915-26. PMID 15207326 DOI: 10.1016/J.Neuroscience.2004.04.046  1
2004 Poon HF, Calabrese V, Scapagnini G, Butterfield DA. Free radicals and brain aging Clinics in Geriatric Medicine. 20: 329-359. PMID 15182885 DOI: 10.1016/J.Cger.2004.02.005  1
2004 Poon HF, Calabrese V, Scapagnini G, Butterfield DA. Free radicals: Key to brain aging and heme oxygenase as a cellular response to oxidative stress Journals of Gerontology - Series a Biological Sciences and Medical Sciences. 59: 478-493. PMID 15123759 DOI: 10.1093/Gerona/59.5.M478  1
2004 Maragos WF, Young KL, Altman CS, Pocernich CB, Drake J, Butterfield DA, Seif I, Holschneider DP, Chen K, Shih JC. Striatal damage and oxidative stress induced by the mitochondrial toxin malonate are reduced in clorgyline-treated rats and MAO-A deficient mice. Neurochemical Research. 29: 741-6. PMID 15098936 DOI: 10.1023/B:Nere.0000018845.82808.45  1
2004 Drake J, Petroze R, Castegna A, Ding Q, Keller JN, Markesbery WR, Lovell MA, Butterfield DA. 4-Hydroxynonenal oxidatively modifies histones: implications for Alzheimer's disease. Neuroscience Letters. 356: 155-8. PMID 15036618 DOI: 10.1016/J.Neulet.2003.11.047  1
2004 Castegna A, Lauderback CM, Mohmmad-Abdul H, Butterfield DA. Modulation of phospholipid asymmetry in synaptosomal membranes by the lipid peroxidation products, 4-hydroxynonenal and acrolein: implications for Alzheimer's disease. Brain Research. 1004: 193-7. PMID 15033435 DOI: 10.1016/J.Brainres.2004.01.036  1
2004 Castegna A, Thongboonkerd V, Klein J, Lynn BC, Wang YL, Osaka H, Wada K, Butterfield DA. Proteomic analysis of brain proteins in the gracile axonal dystrophy (gad) mouse, a syndrome that emanates from dysfunctional ubiquitin carboxyl-terminal hydrolase L-1, reveals oxidation of key proteins. Journal of Neurochemistry. 88: 1540-6. PMID 15009655 DOI: 10.1046/J.1471-4159.2003.02288.X  1
2004 Smuleac V, Butterfield DA, Bhattacharyya D. Permeability and separation characteristics of polypeptide-functionalized polycarbonate track-etched membranes Chemistry of Materials. 16: 2762-2771. DOI: 10.1021/cm035323j  1
2003 Pocernich CB, Butterfield DA. Acrolein inhibits NADH-linked mitochondrial enzyme activity: implications for Alzheimer's disease. Neurotoxicity Research. 5: 515-20. PMID 14715435 DOI: 10.1007/Bf03033161  1
2003 Calabrese V, Scapagnini G, Colombrita C, Ravagna A, Pennisi G, Giuffrida Stella AM, Galli F, Butterfield DA. Redox regulation of heat shock protein expression in aging and neurodegenerative disorders associated with oxidative stress: A nutritional approach Amino Acids. 25: 437-444. PMID 14661103 DOI: 10.1007/s00726-003-0048-2  1
2003 Butterfield DA, Castegna A. Proteomics for the identification of specifically oxidized proteins in brain: technology and application to the study of neurodegenerative disorders. Amino Acids. 25: 419-25. PMID 14661101 DOI: 10.1007/S00726-003-0027-7  1
2003 Drake J, Sultana R, Aksenova M, Calabrese V, Butterfield DA. Elevation of Mitochondrial Glutathione by γ-Glutamylcysteine Ethyl Ester Protects Mitochondria Against Peroxynitrite-Induced Oxidative Stress Journal of Neuroscience Research. 74: 917-927. PMID 14648597 DOI: 10.1002/Jnr.10810  1
2003 Butterfield DA, Castegna A. Proteomic analysis of oxidatively modified proteins in Alzheimer's disease brain: insights into neurodegeneration. Cellular and Molecular Biology (Noisy-Le-Grand, France). 49: 747-51. PMID 14528911  1
2003 Kanski J, Sultana R, Klunk W, Butterfield DA. Antioxidant activity of X-34 in synaptosomal and neuronal systems. Brain Research. 988: 173-9. PMID 14519539 DOI: 10.1016/S0006-8993(03)03369-9  1
2003 Downie AB, Zhang D, Dirk LM, Thacker RR, Pfeiffer JA, Drake JL, Levy AA, Butterfield DA, Buxton JW, Snyder JC. Communication between the maternal testa and the embryo and/or endosperm affect testa attributes in tomato. Plant Physiology. 133: 145-60. PMID 12970482 DOI: 10.1104/Pp.103.022632  1
2003 Butterfield DA, Boyd-Kimball D, Castegna A. Proteomics in Alzheimer's disease: insights into potential mechanisms of neurodegeneration. Journal of Neurochemistry. 86: 1313-27. PMID 12950441 DOI: 10.1046/J.1471-4159.2003.01948.X  1
2003 Calabrese V, Scapagnini G, Ravagna A, Bella R, Butterfield DA, Calvani M, Pennisi G, Giuffrida Stella AM. Disruption of Thiol Homeostasis and Nitrosative Stress in the Cerebrospinal Fluid of Patients with Active Multiple Sclerosis: Evidence for a Protective Role of Acetylcarnitine Neurochemical Research. 28: 1321-1328. PMID 12938853 DOI: 10.1023/A:1024984013069  1
2003 Ding Q, Reinacker K, Dimayuga E, Nukala V, Drake J, Butterfield DA, Dunn JC, Martin S, Bruce-Keller AJ, Keller JN. Role of the proteasome in protein oxidation and neural viability following low-level oxidative stress Febs Letters. 546: 228-232. PMID 12832045 DOI: 10.1016/S0014-5793(03)00582-9  1
2003 Butterfield DA, Pocernich CB. The glutamatergic system and Alzheimer's disease: therapeutic implications. Cns Drugs. 17: 641-52. PMID 12828500 DOI: 10.2165/00023210-200317090-00004  1
2003 Castegna A, Thongboonkerd V, Klein JB, Lynn B, Markesbery WR, Butterfield DA. Proteomic identification of nitrated proteins in Alzheimer's disease brain. Journal of Neurochemistry. 85: 1394-401. PMID 12787059 DOI: 10.1046/J.1471-4159.2003.01786.X  1
2003 Lauderback CM, Drake J, Zhou D, Hackett JM, Castegna A, Kanski J, Tsoras M, Varadarajan S, Butterfield DA. Derivatives of xanthic acid are novel antioxidants: application to synaptosomes. Free Radical Research. 37: 355-65. PMID 12747729 DOI: 10.1080/1071576021000040664  1
2003 Farr SA, Poon HF, Dogrukol-Ak D, Drake J, Banks WA, Eyerman E, Butterfield DA, Morley JE. The antioxidants alpha-lipoic acid and N-acetylcysteine reverse memory impairment and brain oxidative stress in aged SAMP8 mice. Journal of Neurochemistry. 84: 1173-83. PMID 12603840 DOI: 10.1046/J.1471-4159.2003.01580.X  0.56
2003 Drake J, Link CD, Butterfield DA. Oxidative stress precedes fibrillar deposition of Alzheimer's disease amyloid beta-peptide (1-42) in a transgenic Caenorhabditis elegans model. Neurobiology of Aging. 24: 415-20. PMID 12600717 DOI: 10.1016/S0197-4580(02)00225-7  0.56
2003 Turchan J, Pocernich CB, Gairola C, Chauhan A, Schifitto G, Butterfield DA, Buch S, Narayan O, Sinai A, Geiger J, Berger JR, Elford H, Nath A. Oxidative stress in HIV demented patients and protection ex vivo with novel antioxidants. Neurology. 60: 307-14. PMID 12552050 DOI: 10.1212/01.Wnl.0000042048.85204.3D  1
2003 Chauhan A, Turchan J, Pocernich C, Bruce-Keller A, Roth S, Butterfield DA, Major EO, Nath A. Intracellular human immunodeficiency virus Tat expression in astrocytes promotes astrocyte survival but induces potent neurotoxicity at distant sites via axonal transport. The Journal of Biological Chemistry. 278: 13512-9. PMID 12551932 DOI: 10.1074/Jbc.M209381200  1
2003 Butterfield DA, Bhattacharyya D. Chapter 11 Biofunctional membranes: site-specifically immobilized enzyme arrays Membrane Science and Technology. 8: 233-240. DOI: 10.1016/S0927-5193(03)80014-1  1
2002 Kanski J, Aksenova M, Butterfield DA. The hydrophobic environment of Met35 of Alzheimer's Abeta(1-42) is important for the neurotoxic and oxidative properties of the peptide. Neurotoxicity Research. 4: 219-23. PMID 12829402 DOI: 10.1080/10298420290023945  1
2002 Butterfield DA, Castegna A, Lauderback CM, Drake J. Evidence that amyloid beta-peptide-induced lipid peroxidation and its sequelae in Alzheimer's disease brain contribute to neuronal death. Neurobiology of Aging. 23: 655-64. PMID 12392766 DOI: 10.1016/S0197-4580(01)00340-2  1
2002 Castegna A, Aksenov M, Thongboonkerd V, Klein JB, Pierce WM, Booze R, Markesbery WR, Butterfield DA. Proteomic identification of oxidatively modified proteins in Alzheimer's disease brain. Part II: dihydropyrimidinase-related protein 2, alpha-enolase and heat shock cognate 71. Journal of Neurochemistry. 82: 1524-32. PMID 12354300 DOI: 10.1046/J.1471-4159.2002.01103.X  1
2002 Butterfield DA, Griffin S, Munch G, Pasinetti GM. Amyloid beta-peptide and amyloid pathology are central to the oxidative stress and inflammatory cascades under which Alzheimer's disease brain exists. Journal of Alzheimer's Disease : Jad. 4: 193-201. PMID 12226538 DOI: 10.3233/Jad-2002-4309  1
2002 LaFontaine MA, Geddes JW, Butterfield DA. 3-Nitropropionic acid-induced changes in bilayer fluidity in synaptosomal membranes: Implications for Huntington's disease Neurochemical Research. 27: 507-511. PMID 12199156 DOI: 10.1023/A:1019852720521  1
2002 Butterfield DA, Castegna A, Drake J, Scapagnini G, Calabrese V. Vitamin E and neurodegenerative disorders associated with oxidative stress. Nutritional Neuroscience. 5: 229-39. PMID 12168685 DOI: 10.1080/10284150290028954  1
2002 Butterfield D, Castegna A, Pocernich C, Drake J, Scapagnini G, Calabrese V. Nutritional approaches to combat oxidative stress in Alzheimer's disease. The Journal of Nutritional Biochemistry. 13: 444. PMID 12165357 DOI: 10.1016/S0955-2863(02)00205-X  1
2002 Castegna A, Aksenov M, Aksenova M, Thongboonkerd V, Klein JB, Pierce WM, Booze R, Markesbery WR, Butterfield DA. Proteomic identification of oxidatively modified proteins in Alzheimer's disease brain. Part I: creatine kinase BB, glutamine synthase, and ubiquitin carboxy-terminal hydrolase L-1. Free Radical Biology & Medicine. 33: 562-71. PMID 12160938 DOI: 10.1016/S0891-5849(02)00914-0  1
2002 Calabrese V, Scapagnini G, Ravagna A, Giuffrida Stella AM, Butterfield DA. Molecular chaperones and their roles in neural cell differentiation Developmental Neuroscience. 24: 1-13. PMID 12145406 DOI: 10.1159/000064941  1
2002 Butterfield DA, Kanski J. Methionine residue 35 is critical for the oxidative stress and neurotoxic properties of Alzheimer's amyloid beta-peptide 1-42. Peptides. 23: 1299-309. PMID 12128086 DOI: 10.1016/S0196-9781(02)00066-9  1
2002 Drake J, Kanski J, Varadarajan S, Tsoras M, Butterfield DA. Elevation of brain glutathione by gamma-glutamylcysteine ethyl ester protects against peroxynitrite-induced oxidative stress. Journal of Neuroscience Research. 68: 776-84. PMID 12111838 DOI: 10.1002/Jnr.10266  1
2002 LaFontaine MA, Mattson MP, Butterfield DA. Oxidative stress in synaptosomal proteins from mutant presenilin-1 knock-in mice: Implications for familial Alzheimer's disease Neurochemical Research. 27: 417-421. PMID 12064358 DOI: 10.1023/A:1015560116208  1
2002 Kanski J, Aksenova M, Schöneich C, Butterfield DA. Substitution of isoleucine-31 by helical-breaking proline abolishes oxidative stress and neurotoxic properties of Alzheimer's amyloid beta-peptide. Free Radical Biology & Medicine. 32: 1205-11. PMID 12031904 DOI: 10.1016/S0891-5849(02)00821-3  1
2002 Butterfield DA, Lauderback CM. Lipid peroxidation and protein oxidation in Alzheimer's disease brain: potential causes and consequences involving amyloid beta-peptide-associated free radical oxidative stress. Free Radical Biology & Medicine. 32: 1050-60. PMID 12031889 DOI: 10.1016/S0891-5849(02)00794-3  1
2002 Kanski J, Aksenova M, Stoyanova A, Butterfield DA. Ferulic acid antioxidant protection against hydroxyl and peroxyl radical oxidation in synaptosomal and neuronal cell culture systems in vitro: structure-activity studies. The Journal of Nutritional Biochemistry. 13: 273-281. PMID 12015157 DOI: 10.1016/S0955-2863(01)00215-7  1
2002 Kanski J, Varadarajan S, Aksenova M, Butterfield DA. Role of glycine-33 and methionine-35 in Alzheimer's amyloid beta-peptide 1-42-associated oxidative stress and neurotoxicity. Biochimica Et Biophysica Acta. 1586: 190-8. PMID 11959460 DOI: 10.1016/S0925-4439(01)00097-7  1
2002 Lauderback CM, Kanski J, Hackett JM, Maeda N, Kindy MS, Butterfield DA. Apolipoprotein E modulates Alzheimer's Abeta(1-42)-induced oxidative damage to synaptosomes in an allele-specific manner. Brain Research. 924: 90-7. PMID 11743999 DOI: 10.1016/S0006-8993(01)03228-0  1
2002 Butterfield DA, Pocernich CB, Drake J. Elevated glutathione as a therapeutic strategy in Alzheimer's disease Drug Development Research. 56: 428-437. DOI: 10.1002/Ddr.10095  1
2001 Butterfield DA, Drake J, Pocernich C, Castegna A. Evidence of oxidative damage in Alzheimer's disease brain: central role for amyloid beta-peptide. Trends in Molecular Medicine. 7: 548-54. PMID 11733217 DOI: 10.1016/S1471-4914(01)02173-6  1
2001 Kanski J, Drake J, Aksenova M, Engman L, Butterfield DA. Antioxidant activity of the organotellurium compound 3-[4-(N,N-dimethylamino)benzenetellurenyl]propanesulfonic acid against oxidative stress in synaptosomal membrane systems and neuronal cultures. Brain Research. 911: 12-21. PMID 11489439 DOI: 10.1016/S0006-8993(01)02541-0  1
2001 Lauderback CM, Hackett JM, Huang FF, Keller JN, Szweda LI, Markesbery WR, Butterfield DA. The glial glutamate transporter, GLT-1, is oxidatively modified by 4-hydroxy-2-nonenal in the Alzheimer's disease brain: the role of Abeta1-42. Journal of Neurochemistry. 78: 413-6. PMID 11461977 DOI: 10.1046/J.1471-4159.2001.00451.X  1
2001 Zhou D, Lauderback CM, Yu T, Brown SA, Butterfield DA, Thompson JS. D609 inhibits ionizing radiation-induced oxidative damage by acting as a potent antioxidant. The Journal of Pharmacology and Experimental Therapeutics. 298: 103-9. PMID 11408530  1
2001 Pocernich CB, Cardin AL, Racine CL, Lauderback CM, Butterfield DA. Glutathione elevation and its protective role in acrolein-induced protein damage in synaptosomal membranes: relevance to brain lipid peroxidation in neurodegenerative disease. Neurochemistry International. 39: 141-9. PMID 11408093 DOI: 10.1016/S0197-0186(01)00012-2  1
2001 Varadarajan S, Kanski J, Aksenova M, Lauderback C, Butterfield DA. Different mechanisms of oxidative stress and neurotoxicity for Alzheimer's A beta(1--42) and A beta(25--35). Journal of the American Chemical Society. 123: 5625-31. PMID 11403592 DOI: 10.1021/ja010452r  1
2001 Kanski J, Lauderback C, Butterfield DA. 5-Aminosalicylic acid protection against oxidative damage to synaptosomal membranes by alkoxyl radicals in vitro. Neurochemical Research. 26: 23-9. PMID 11358278 DOI: 10.1023/A:1007620330168  1
2001 Butterfield DA, Kanski J. Brain protein oxidation in age-related neurodegenerative disorders that are associated with aggregated proteins. Mechanisms of Ageing and Development. 122: 945-62. PMID 11348660 DOI: 10.1016/S0047-6374(01)00249-4  1
2001 Lauderback CM, Hackett JM, Keller JN, Varadarajan S, Szweda L, Kindy M, Markesbery WR, Butterfield DA. Vulnerability of synaptosomes from apoE knock-out mice to structural and oxidative modifications induced by A beta(1-40): implications for Alzheimer's disease. Biochemistry. 40: 2548-54. PMID 11327877 DOI: 10.1021/Bi002312K  1
2001 Aksenov MY, Aksenova MV, Butterfield DA, Geddes JW, Markesbery WR. Protein oxidation in the brain in Alzheimer's disease. Neuroscience. 103: 373-83. PMID 11246152 DOI: 10.1016/S0306-4522(00)00580-7  1
2001 Yatin SM, Yatin M, Varadarajan S, Ain KB, Butterfield DA. Role of spermine in amyloid beta-peptide-associated free radical-induced neurotoxicity. Journal of Neuroscience Research. 63: 395-401. PMID 11223914 DOI: 10.1002/1097-4547(20010301)63:5<395::Aid-Jnr1034>3.0.Co;2-Q  0.76
2001 Butterfield DA, Bhattacharyya D, Daunert S, Bachas L. Catalytic biofunctional membranes containing site-specifically immobilized enzyme arrays: A review Journal of Membrane Science. 181: 29-37. DOI: 10.1016/S0376-7388(00)00342-2  1
2000 Yatin SM, Varadarajan S, Butterfield DA. Vitamin E Prevents Alzheimer's Amyloid beta-Peptide (1-42)-Induced Neuronal Protein Oxidation and Reactive Oxygen Species Production. Journal of Alzheimer's Disease : Jad. 2: 123-131. PMID 12214102 DOI: 10.3233/Jad-2000-2212  0.76
2000 Wondrak GT, Varadarajan S, Butterfield DA, Jacobson MK. Formation of a protein-bound pyrazinium free radical cation during glycation of histone H1. Free Radical Biology & Medicine. 29: 557-67. PMID 11025199 DOI: 10.1016/S0891-5849(00)00406-8  1
2000 Maragos WF, Jakel R, Chesnut D, Pocernich CB, Butterfield DA, St Clair D, Cass WA. Methamphetamine toxicity is attenuated in mice that overexpress human manganese superoxide dismutase. Brain Research. 878: 218-22. PMID 10996156 DOI: 10.1016/S0006-8993(00)02707-4  1
2000 La Fontaine MA, Geddes JW, Banks A, Allan Butterfield D. Effect of exogenous and endogenous antioxidants on 3-nitropropionic acid-induced in vivo oxidative stress and striatal lesions: Insights into Huntington's disease Journal of Neurochemistry. 75: 1709-1715. PMID 10987854 DOI: 10.1046/J.1471-4159.2000.0751709.X  0.36
2000 Varadarajan S, Yatin S, Aksenova M, Butterfield DA. Review: Alzheimer's amyloid beta-peptide-associated free radical oxidative stress and neurotoxicity. Journal of Structural Biology. 130: 184-208. PMID 10940225 DOI: 10.1006/Jsbi.2000.4274  1
2000 Lauderback CM, Breier AM, Hackett J, Varadarajan S, Goodlett-Mercer J, Butterfield DA. The pyrrolopyrimidine U101033E is a potent free radical scavenger and prevents Fe(II)-induced lipid peroxidation in synaptosomal membranes. Biochimica Et Biophysica Acta. 1501: 149-61. PMID 10838188 DOI: 10.1016/S0925-4439(00)00015-6  1
2000 Keller JN, Lauderback CM, Butterfield DA, Kindy MS, Yu J, Markesbery WR. Amyloid beta-peptide effects on synaptosomes from apolipoprotein E-deficient mice. Journal of Neurochemistry. 74: 1579-86. PMID 10737615 DOI: 10.1046/J.1471-4159.2000.0741579.X  1
2000 La Fontaine MA, Geddes JW, Banks A, Butterfield DA. 3-nitropropionic acid induced in vivo protein oxidation in striatal and cortical synaptosomes: insights into Huntington's disease. Brain Research. 858: 356-62. PMID 10708687 DOI: 10.1016/S0006-8993(00)01948-X  1
2000 Pocernich CB, La Fontaine M, Butterfield DA. In-vivo glutathione elevation protects against hydroxyl free radical-induced protein oxidation in rat brain. Neurochemistry International. 36: 185-91. PMID 10676851 DOI: 10.1016/S0197-0186(99)00126-6  1
1999 Lauderback CM, Harris-White ME, Wang Y, Pedigo NW, Carney JM, Butterfield DA. Amyloid beta-peptide inhibits Na+-dependent glutamate uptake. Life Sciences. 65: 1977-81. PMID 10576449 DOI: 10.1016/S0024-3205(99)00459-2  1
1999 Varadarajan S, Yatin S, Kanski J, Jahanshahi F, Butterfield DA. Methionine residue 35 is important in amyloid beta-peptide-associated free radical oxidative stress. Brain Research Bulletin. 50: 133-41. PMID 10535332 DOI: 10.1016/S0361-9230(99)00093-3  1
1999 Butterfield DA, Yatin SM, Varadarajan S, Koppal T. Amyloid beta-peptide-associated free radical oxidative stress, neurotoxicity, and Alzheimer's disease. Methods in Enzymology. 309: 746-68. PMID 10507060 DOI: 10.1016/S0076-6879(99)09050-3  1
1999 Aksenova MV, Aksenov MY, Markesbery WR, Butterfield DA. Aging in a dish: age-dependent changes of neuronal survival, protein oxidation, and creatine kinase BB expression in long-term hippocampal cell culture. Journal of Neuroscience Research. 58: 308-17. PMID 10502287 DOI: 10.1002/(Sici)1097-4547(19991015)58:2<308::Aid-Jnr11>3.0.Co;2-#  1
1999 Aksenov MY, Tucker HM, Nair P, Aksenova MV, Butterfield DA, Estus S, Markesbery WR. The expression of several mitochondrial and nuclear genes encoding the subunits of electron transport chain enzyme complexes, cytochrome c oxidase, and NADH dehydrogenase, in different brain regions in Alzheimer's disease. Neurochemical Research. 24: 767-74. PMID 10447460 DOI: 10.1023/A:1020783614031  1
1999 DeAtley SM, Aksenov MY, Aksenova MV, Jordan B, Carney JM, Butterfield DA. Adriamycin-induced changes of creatine kinase activity in vivo and in cardiomyocyte culture. Toxicology. 134: 51-62. PMID 10413188 DOI: 10.1016/S0300-483X(99)00039-6  1
1999 Yatin SM, Aksenov M, Butterfield DA. The antioxidant vitamin E modulates amyloid beta-peptide-induced creatine kinase activity inhibition and increased protein oxidation: implications for the free radical hypothesis of Alzheimer's disease. Neurochemical Research. 24: 427-35. PMID 10215518 DOI: 10.1023/A:1020997903147  1
1999 DeAtley SM, Aksenov MY, Aksenova MV, Harris B, Hadley R, Cole Harper P, Carney JM, Butterfield DA. Antioxidants protect against reactive oxygen species associated with adriamycin-treated cardiomyocytes. Cancer Letters. 136: 41-6. PMID 10211937 DOI: 10.1016/S0304-3835(98)00306-1  1
1999 Koppal T, Drake J, Butterfield DA. In vivo modulation of rodent glutathione and its role in peroxynitrite-induced neocortical synaptosomal membrane protein damage. Biochimica Et Biophysica Acta. 1453: 407-411. PMID 10101259 DOI: 10.1016/S0925-4439(99)00014-9  0.56
1999 Kanski J, Koppal T, Butterfield DA. Investigation of Peroxynitrite Induced Oxidative Stress in Red Blood Cells Monitored by Luminol-Dependent Chemiluminescence. Analytical Letters. 32: 1183-1192. DOI: 10.1080/00032719908542887  1
1998 Aksenov MY, Tucker HM, Nair P, Aksenova MV, Butterfield DA, Estus S, Markesbery WR. The expression of key oxidative stress-handling genes in different brain regions in Alzheimer's disease. Journal of Molecular Neuroscience : Mn. 11: 151-64. PMID 10096042 DOI: 10.1385/Jmn:11:2:151  1
1998 Butterfield DA, Koppal T, Howard B, Subramaniam R, Hall N, Hensley K, Yatin S, Allen K, Aksenov M, Aksenova M, Carney J. Structural and functional changes in proteins induced by free radical-mediated oxidative stress and protective action of the antioxidants N-tert-butyl-alpha-phenylnitrone and vitamin E. Annals of the New York Academy of Sciences. 854: 448-62. PMID 9928452 DOI: 10.1111/J.1749-6632.1998.Tb09924.X  1
1998 DeAtley SM, Aksenov MY, Aksenova MV, Carney JM, Butterfield DA. Adriamycin induces protein oxidation in erythrocyte membranes. Pharmacology & Toxicology. 83: 62-8. PMID 9783322 DOI: 10.1111/J.1600-0773.1998.Tb01445.X  1
1998 Aksenov MY, Aksenova MV, Markesbery WR, Butterfield DA. Amyloid beta-peptide (1-40)-mediated oxidative stress in cultured hippocampal neurons. Protein carbonyl formation, CK BB expression, and the level of Cu, Zn, and Mn SOD mRNA. Journal of Molecular Neuroscience : Mn. 10: 181-92. PMID 9770641 DOI: 10.1007/Bf02761773  1
1998 Gabbita SP, Subramaniam R, Allouch F, Carney JM, Butterfield DA. Effects of mitochondrial respiratory stimulation on membrane lipids and proteins: an electron paramagnetic resonance investigation. Biochimica Et Biophysica Acta. 1372: 163-73. PMID 9675268 DOI: 10.1016/S0005-2736(98)00040-6  1
1998 Koppal T, Subramaniam R, Drake J, Prasad MR, Dhillon H, Butterfield DA. Vitamin E protects against Alzheimer's amyloid peptide (25-35)-induced changes in neocortical synaptosomal membrane lipid structure and composition. Brain Research. 786: 270-3. PMID 9555054 DOI: 10.1016/S0006-8993(97)01466-2  0.56
1998 Aksenova MV, Aksenov MY, Carney JM, Butterfield DA. Protein oxidation and enzyme activity decline in old brown Norway rats are reduced by dietary restriction. Mechanisms of Ageing and Development. 100: 157-68. PMID 9541136 DOI: 10.1016/S0047-6374(97)00133-4  1
1998 Bruce-Keller AJ, Begley JG, Fu W, Butterfield DA, Bredesen DE, Hutchins JB, Hensley K, Mattson MP. Bcl-2 protects isolated plasma and mitochondrial membranes against lipid peroxidation induced by hydrogen peroxide and amyloid beta-peptide. Journal of Neurochemistry. 70: 31-9. PMID 9422344 DOI: 10.1046/J.1471-4159.1998.70010031.X  1
1997 Gabbita SP, Butterfield DA, Hensley K, Shaw W, Carney JM. Aging and caloric restriction affect mitochondrial respiration and lipid membrane status: an electron paramagnetic resonance investigation. Free Radical Biology & Medicine. 23: 191-201. PMID 9199881 DOI: 10.1016/S0891-5849(97)00043-9  1
1997 Butterfield DA, Hensley K, Cole P, Subramaniam R, Aksenov M, Aksenova M, Bummer PM, Haley BE, Carney JM. Oxidatively induced structural alteration of glutamine synthetase assessed by analysis of spin label incorporation kinetics: relevance to Alzheimer's disease. Journal of Neurochemistry. 68: 2451-7. PMID 9166739 DOI: 10.1046/J.1471-4159.1997.68062451.X  1
1997 Hall NC, Carney JM, Plante OJ, Cheng M, Butterfield DA. Effect of 2-cyclohexene-1-one-induced glutathione diminution on ischemia/reperfusion-induced alterations in the physical state of brain synaptosomal membrane proteins and lipids. Neuroscience. 77: 283-90. PMID 9044393 DOI: 10.1016/S0306-4522(96)00430-7  1
1997 Butterfield DA, Howard BJ, Yatin S, Allen KL, Carney JM. Free radical oxidation of brain proteins in accelerated senescence and its modulation by N-tert-butyl-alpha-phenylnitrone. Proceedings of the National Academy of Sciences of the United States of America. 94: 674-8. PMID 9012843 DOI: 10.1073/Pnas.94.2.674  1
1996 Butterfield DA, Martin L, Carney JM, Hensley K. A beta (25-35) peptide displays H2O2-like reactivity towards aqueous Fe2+, nitroxide spin probes, and synaptosomal membrane proteins. Life Sciences. 58: 217-28. PMID 9499162 DOI: 10.1016/0024-3205(95)02279-1  1
1996 Aksenov MY, Aksenova MV, Carney JM, Butterfield DA. Alpha 1-antichymotrypsin interaction with A beta (1-42) does not inhibit fibril formation but attenuates the peptide toxicity. Neuroscience Letters. 217: 117-20. PMID 8916086 DOI: 10.1016/0304-3940(96)13082-2  1
1996 Howard BJ, Yatin S, Hensley K, Allen KL, Kelly JP, Carney J, Butterfield DA. Prevention of hyperoxia-induced alterations in synaptosomal membrane-associated proteins by N-tert-butyl-alpha-phenylnitrone and 4-hydroxy-2,2,6,6-tetramethylpiperidin-1-oxyl (Tempol). Journal of Neurochemistry. 67: 2045-50. PMID 8863512 DOI: 10.1046/J.1471-4159.1996.67052045.X  0.4
1996 Aksenova MV, Aksenov MY, Butterfield DA, Carney JM. alpha-1-antichymotrypsin interaction with A beta (1-40) inhibits fibril formation but does not affect the peptide toxicity. Neuroscience Letters. 211: 45-8. PMID 8809844 DOI: 10.1016/0304-3940(96)12717-8  1
1996 Aksenov MY, Aksenova MV, Butterfield DA, Hensley K, Vigo-Pelfrey C, Carney JM. Glutamine synthetase-induced enhancement of beta-amyloid peptide A beta (1-40) neurotoxicity accompanied by abrogation of fibril formation and A beta fragmentation. Journal of Neurochemistry. 66: 2050-6. PMID 8780035 DOI: 10.1046/j.1471-4159.1996.66052050.x  1
1996 Harris ME, Wang Y, Pedigo NW, Hensley K, Butterfield DA, Carney JM. Amyloid beta peptide (25-35) inhibits Na+-dependent glutamate uptake in rat hippocampal astrocyte cultures. Journal of Neurochemistry. 67: 277-86. PMID 8667003 DOI: 10.1046/J.1471-4159.1996.67010277.X  1
1995 Hall NC, Dempsey RJ, Carney JM, Donaldson DL, Butterfield DA. Structural alterations in synaptosomal membrane-associated proteins and lipids by transient middle cerebral artery occlusion in the cat. Neurochemical Research. 20: 1161-9. PMID 8746801 DOI: 10.1007/BF00995379  1
1995 Hall NC, Carney JM, Cheng M, Butterfield DA. Prevention of ischemia/reperfusion-induced alterations in synaptosomal membrane-associated proteins and lipids by N-tert-butyl-alpha-phenylnitrone and difluoromethylornithine. Neuroscience. 69: 591-600. PMID 8552252 DOI: 10.1016/0306-4522(95)00289-U  1
1995 Harris ME, Hensley K, Butterfield DA, Leedle RA, Carney JM. Direct evidence of oxidative injury produced by the Alzheimer's beta-amyloid peptide (1-40) in cultured hippocampal neurons. Experimental Neurology. 131: 193-202. PMID 7895820 DOI: 10.1016/0014-4886(95)90041-1  1
1995 Mattson MP, Carney JW, Butterfield DA. A tombstone in Alzheimer's? [8] Nature. 373: 481. PMID 7845457 DOI: 10.1038/373481A0  1
1995 Hensley K, Howard BJ, Carney JM, Butterfield DA. Membrane protein alterations in rodent erythrocytes and synaptosomes due to aging and hyperoxia. Biochimica Et Biophysica Acta. 1270: 203-6. PMID 7727544 DOI: 10.1016/0925-4439(95)00043-4  1
1995 Hall NC, Carney JM, Cheng MS, Butterfield DA. Ischemia/reperfusion-induced changes in membrane proteins and lipids of gerbil cortical synaptosomes. Neuroscience. 64: 81-9. PMID 7708217 DOI: 10.1016/0306-4522(94)00385-I  1
1995 Hensley K, Hall N, Subramaniam R, Cole P, Harris M, Aksenov M, Aksenova M, Gabbita SP, Wu JF, Carney JM. Brain regional correspondence between Alzheimer's disease histopathology and biomarkers of protein oxidation. Journal of Neurochemistry. 65: 2146-56. PMID 7595501 DOI: 10.1046/J.1471-4159.1995.65052146.X  1
1995 Aksenov MYu, Aksenova MV, Harris ME, Hensley K, Butterfield DA, Carney JM. Enhancement of beta-amyloid peptide A beta(1-40)-mediated neurotoxicity by glutamine synthetase. Journal of Neurochemistry. 65: 1899-902. PMID 7561891 DOI: 10.1046/j.1471-4159.1995.65041899.x  1
1994 Butterfield DA, Sun B, Bellary S, Arden WA, Anderson KW. Effect of endotoxin on lipid order and motion in erythrocyte membranes. Biochimica Et Biophysica Acta. 1225: 231-4. PMID 8280792 DOI: 10.1016/0925-4439(94)90083-3  1
1994 Carney JM, Smith CD, Carney AM, Butterfield DA. Aging- and oxygen-induced modifications in brain biochemistry and behavior. Annals of the New York Academy of Sciences. 738: 44-53. PMID 7832454 DOI: 10.1111/j.1749-6632.1994.tb21788.x  1
1991 Yacko MA, Vanaman TC, Butterfield DA. Spin labeling studies of wheat germ calmodulin in solution Bba - Biomembranes. 1064: 7-12. PMID 1851042 DOI: 10.1016/0005-2736(91)90405-W  1
1991 Butterfield DA, Schneider AM, Rangachari A. Electron paramagnetic resonance studies of the effects of tri-n-butyltin on the physical state of proteins and lipids in erythrocyte membranes. Chemical Research in Toxicology. 4: 141-3. PMID 1664254 DOI: 10.1021/TX00020A002  1
1989 Wyse JW, Blank ME, Maynard CL, Diedrich DF, Butterfield DA. Electron spin resonance investigation of the interaction of the anion and glucose transport inhibitor, p-azidobenzylphlorizin, with the human red cell membrane Bba - Biomembranes. 979: 127-131. PMID 2537105 DOI: 10.1016/0005-2736(89)90532-4  1
1989 Wyse JW, Butterfield DA. Interaction of hemin with erythrocyte membranes: alterations in the physical state of the major sialoglycoprotein Bba - Biomembranes. 979: 121-126. PMID 2537104 DOI: 10.1016/0005-2736(89)90531-2  1
1987 Wyse JW, Barker R, Franco RS, Martelo O, Butterfield DA. Electron spin resonance (ESR) studies of skeletal protein interactions in human erythrocyte membranes exposed to polyanions and in membranes prepared from inositol hexaphosphate (IHP)-incorporated low-affinity erythrocytes Biochemical and Biophysical Research Communications. 144: 779-786. PMID 3034263 DOI: 10.1016/S0006-291X(87)80032-3  1
1982 Feix JB, Green LL, Butterfield DA. Effects of phytohaemagglutinin, wheat-germ agglutinin, and concanavalin-A on the physical state of sialic acid and membrane proteins in human erythrocyte ghosts: a spin label study. Life Sciences. 31: 1001-9. PMID 6290810 DOI: 10.1016/0024-3205(82)90172-2  1
1980 Markesbery WR, Leung PK, Butterfield DA. Spin label and biochemical studies of erythrocyte membranes in Alzheimer's disease Journal of the Neurological Sciences. 45: 323-330. PMID 6245187 DOI: 10.1016/0022-510X(80)90175-6  1
1978 Butterfield DA, Leung PK. Erythrocyte membrane fluidity in chicken muscular dystrophy Life Sciences. 22: 1783-1787. PMID 209273 DOI: 10.1016/0024-3205(78)90593-3  1
1976 Butterfield DA, Roses AD, Appel SH, Chesnut DB. Electron spin resonance studies of membrane proteins in erythrocytes in myotonic muscular dystrophy. Archives of Biochemistry and Biophysics. 177: 226-34. PMID 187121 DOI: 10.1016/0003-9861(76)90432-X  1
1975 Butterfield DA, Crumbliss AL, Chesnut DB. Radical decay kinetics in ferrocytochrome c model membranes. A spin label study. Journal of the American Chemical Society. 97: 1388-93. PMID 166112 DOI: 10.1002/Chin.197522411  0.48
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