Year |
Citation |
Score |
2012 |
Schmechel DE, Edwards CL. Fibromyalgia, mood disorders, and intense creative energy: A1AT polymorphisms are not always silent. Neurotoxicology. 33: 1454-72. PMID 22414631 DOI: 10.1016/J.Neuro.2012.03.001 |
0.301 |
|
2010 |
Liang WS, Dunckley T, Beach TG, Grover A, Mastroeni D, Ramsey K, Caselli RJ, Kukull WA, McKeel D, Morris JC, Hulette CM, Schmechel D, Reiman EM, Rogers J, Stephan DA. Neuronal gene expression in non-demented individuals with intermediate Alzheimer's Disease neuropathology. Neurobiology of Aging. 31: 549-66. PMID 18572275 DOI: 10.1016/J.Neurobiolaging.2008.05.013 |
0.42 |
|
2008 |
Züchner S, Gilbert JR, Martin ER, Leon-Guerrero CR, Xu PT, Browning C, Bronson PG, Whitehead P, Schmechel DE, Haines JL, Pericak-Vance MA. Linkage and association study of late-onset Alzheimer disease families linked to 9p21.3. Annals of Human Genetics. 72: 725-31. PMID 18761660 DOI: 10.1111/J.1469-1809.2008.00474.X |
0.378 |
|
2008 |
Sullivan PM, Mace BE, Estrada JC, Schmechel DE, Alberts MJ. Human apolipoprotein E4 targeted replacement mice show increased prevalence of intracerebral hemorrhage associated with vascular amyloid deposition. Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association. 17: 303-11. PMID 18755411 DOI: 10.1016/J.Jstrokecerebrovasdis.2008.03.011 |
0.352 |
|
2008 |
Carney RM, Slifer MA, Lin PI, Gaskell PC, Scott WK, Potocky CF, Hulette CM, Welsh-Bohmer KA, Schmechel DE, Vance JM, Pericak-Vance MA. Longitudinal follow-up of late-onset Alzheimer disease families. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 147: 571-8. PMID 18361431 DOI: 10.1002/Ajmg.B.30590 |
0.319 |
|
2008 |
Liang WS, Reiman EM, Valla J, Dunckley T, Beach TG, Grover A, Niedzielko TL, Schneider LE, Mastroeni D, Caselli R, Kukull W, Morris JC, Hulette CM, Schmechel D, Rogers J, et al. Alzheimer's disease is associated with reduced expression of energy metabolism genes in posterior cingulate neurons. Proceedings of the National Academy of Sciences of the United States of America. 105: 4441-6. PMID 18332434 DOI: 10.1073/Pnas.0709259105 |
0.389 |
|
2008 |
Liang WS, Dunckley T, Beach TG, Grover A, Mastroeni D, Ramsey K, Caselli RJ, Kukull WA, McKeel D, Morris JC, Hulette CM, Schmechel D, Reiman EM, Rogers J, Stephan DA. Altered neuronal gene expression in brain regions differentially affected by Alzheimer's disease: a reference data set. Physiological Genomics. 33: 240-56. PMID 18270320 DOI: 10.1152/Physiolgenomics.00242.2007 |
0.429 |
|
2007 |
Xu PT, Li YJ, Qin XJ, Kroner C, Green-Odlum A, Xu H, Wang TY, Schmechel DE, Hulette CM, Ervin J, Hauser M, Haines J, Pericak-Vance MA, Gilbert JR. A SAGE study of apolipoprotein E3/3, E3/4 and E4/4 allele-specific gene expression in hippocampus in Alzheimer disease. Molecular and Cellular Neurosciences. 36: 313-31. PMID 17822919 DOI: 10.1016/J.Mcn.2007.06.009 |
0.416 |
|
2007 |
Liang WS, Dunckley T, Beach TG, Grover A, Mastroeni D, Walker DG, Caselli RJ, Kukull WA, McKeel D, Morris JC, Hulette C, Schmechel D, Alexander GE, Reiman EM, Rogers J, et al. Gene expression profiles in anatomically and functionally distinct regions of the normal aged human brain. Physiological Genomics. 28: 311-22. PMID 17077275 DOI: 10.1152/Physiolgenomics.00208.2006 |
0.405 |
|
2006 |
Lin PI, Martin ER, Bronson PG, Browning-Large C, Small GW, Schmechel DE, Welsh-Bohmer KA, Haines JL, Gilbert JR, Pericak-Vance MA. Exploring the association of glyceraldehyde-3-phosphate dehydrogenase gene and Alzheimer disease. Neurology. 67: 64-8. PMID 16832079 DOI: 10.1212/01.Wnl.0000223438.90113.4E |
0.333 |
|
2006 |
Lin PI, Martin ER, Browning-Large CA, Schmechel DE, Welsh-Bohmer KA, Doraiswamy PM, Gilbert JR, Haines JL, Pericak-Vance MA. Parsing the genetic heterogeneity of chromosome 12q susceptibility genes for Alzheimer disease by family-based association analysis. Neurogenetics. 7: 157-65. PMID 16770605 DOI: 10.1007/S10048-006-0047-Z |
0.316 |
|
2006 |
Dunckley T, Beach TG, Ramsey KE, Grover A, Mastroeni D, Walker DG, LaFleur BJ, Coon KD, Brown KM, Caselli R, Kukull W, Higdon R, McKeel D, Morris JC, Hulette C, ... Schmechel D, et al. Gene expression correlates of neurofibrillary tangles in Alzheimer's disease. Neurobiology of Aging. 27: 1359-71. PMID 16242812 DOI: 10.1016/J.Neurobiolaging.2005.08.013 |
0.424 |
|
2006 |
Xu PT, Li YJ, Qin XJ, Scherzer CR, Xu H, Schmechel DE, Hulette CM, Ervin J, Gullans SR, Haines J, Pericak-Vance MA, Gilbert JR. Differences in apolipoprotein E3/3 and E4/4 allele-specific gene expression in hippocampus in Alzheimer disease. Neurobiology of Disease. 21: 256-75. PMID 16198584 DOI: 10.1016/J.Nbd.2005.07.004 |
0.412 |
|
2006 |
Bronson PG, Wall NN, Haines JL, Schmechel DE, Gilbert JR, Pericak-Vance MA, Martin ER. P1-345: Evidence for association between late-onset Alzheimer's disease and MTHFR on chromosome 1 Alzheimer's & Dementia. 2: S198-S198. DOI: 10.1016/J.Jalz.2006.05.723 |
0.353 |
|
2005 |
Martin ER, Bronson PG, Li YJ, Wall N, Chung RH, Schmechel DE, Small G, Xu PT, Bartlett J, Schnetz-Boutaud N, Haines JL, Gilbert JR, Pericak-Vance MA. Interaction between the alpha-T catenin gene (VR22) and APOE in Alzheimer's disease. Journal of Medical Genetics. 42: 787-92. PMID 16199552 DOI: 10.1136/Jmg.2004.029553 |
0.395 |
|
2005 |
Malek G, Johnson LV, Mace BE, Saloupis P, Schmechel DE, Rickman DW, Toth CA, Sullivan PM, Bowes Rickman C. Apolipoprotein E allele-dependent pathogenesis: a model for age-related retinal degeneration. Proceedings of the National Academy of Sciences of the United States of America. 102: 11900-5. PMID 16079201 DOI: 10.1016/J.Ajo.2006.01.010 |
0.332 |
|
2005 |
Corder EH, Ervin JF, Lockhart E, Szymanski MH, Schmechel DE, Hulette CM. Cardiovascular damage in Alzheimer disease: autopsy findings from the Bryan ADRC. Journal of Biomedicine & Biotechnology. 2005: 189-97. PMID 16046825 DOI: 10.1155/Jbb.2005.189 |
0.386 |
|
2005 |
Mott RT, Dickson DW, Trojanowski JQ, Zhukareva V, Lee VM, Forman M, Van Deerlin V, Ervin JF, Wang DS, Schmechel DE, Hulette CM. Neuropathologic, biochemical, and molecular characterization of the frontotemporal dementias. Journal of Neuropathology and Experimental Neurology. 64: 420-8. PMID 15892300 DOI: 10.1093/Jnen/64.5.420 |
0.326 |
|
2005 |
Wang C, Wilson WA, Moore SD, Mace BE, Maeda N, Schmechel DE, Sullivan PM. Human apoE4-targeted replacement mice display synaptic deficits in the absence of neuropathology. Neurobiology of Disease. 18: 390-8. PMID 15686968 DOI: 10.1016/J.Nbd.2004.10.013 |
0.378 |
|
2004 |
Nicodemus KK, Stenger JE, Schmechel DE, Welsh-Bohmer KA, Saunders AM, Roses AD, Gilbert JR, Vance JM, Haines JL, Pericak-Vance MA, Martin ER. Comprehensive association analysis of APOE regulatory region polymorphisms in Alzheimer disease. Neurogenetics. 5: 201-8. PMID 15455263 DOI: 10.1007/S10048-004-0189-9 |
0.381 |
|
2004 |
Ervin JF, Pannell C, Szymanski M, Welsh-Bohmer K, Schmechel DE, Hulette CM. Vascular smooth muscle actin is reduced in Alzheimer disease brain: a quantitative analysis. Journal of Neuropathology and Experimental Neurology. 63: 735-41. PMID 15290898 DOI: 10.1093/Jnen/63.7.735 |
0.384 |
|
2004 |
van der Walt JM, Dementieva YA, Martin ER, Scott WK, Nicodemus KK, Kroner CC, Welsh-Bohmer KA, Saunders AM, Roses AD, Small GW, Schmechel DE, Murali Doraiswamy P, Gilbert JR, Haines JL, Vance JM, et al. Analysis of European mitochondrial haplogroups with Alzheimer disease risk. Neuroscience Letters. 365: 28-32. PMID 15234467 DOI: 10.1016/J.Neulet.2004.04.051 |
0.37 |
|
2004 |
Sullivan PM, Mace BE, Maeda N, Schmechel DE. Marked regional differences of brain human apolipoprotein E expression in targeted replacement mice. Neuroscience. 124: 725-33. PMID 15026113 DOI: 10.1016/J.Neuroscience.2003.10.011 |
0.36 |
|
2004 |
Colton CA, Needham LK, Brown C, Cook D, Rasheed K, Burke JR, Strittmatter WJ, Schmechel DE, Vitek MP. APOE genotype-specific differences in human and mouse macrophage nitric oxide production. Journal of Neuroimmunology. 147: 62-7. PMID 14741429 DOI: 10.1016/J.Jneuroim.2003.10.015 |
0.379 |
|
2004 |
Quan H, Haines JL, Sanchez-Boutard N, Small G, Roses A, Schmechel D, Welsh-Bohmer K, Xu P, Li Y, Gilbert JR, Vance JM, Pericak-Vance MA. P4-138 Genomic convergence on chromosome 12 in Alzheimer's disease Neurobiology of Aging. 25: S514. DOI: 10.1016/S0197-4580(04)81696-8 |
0.313 |
|
2004 |
Martin E, Bronson P, Jiang L, Welsh-Bohmer K, Schmechel D, Small G, Haines J, Gilbert J, Pericak-Vance M, Moore J. P4-134 A multilocus association analysis of APOE, LRP1 and A2M in Alzheimer disease Neurobiology of Aging. 25: S513. DOI: 10.1016/S0197-4580(04)81692-0 |
0.38 |
|
2004 |
Gilbert JR, Xu P, Li Y, Qin X, Schmechel D, Hulette C, McLaurin A, Scherzer C, Gullans SR, Haines JL, Pericak-Vance MA. P4-103 APOE allele specific gene expression in Alzheimer's and control hippocampus Neurobiology of Aging. 25. DOI: 10.1016/S0197-4580(04)81661-0 |
0.368 |
|
2004 |
Li Y, Oliveira SA, Qin X, Roses AD, Schmechel D, Welsh-Bohmer KA, Haines JL, Pericak-Vance MA, Vance JM. P4-088 Association analysis of interleukin 1 (IL-1) polymorphisms with age-at-onset and risk of Alzheimer disease Neurobiology of Aging. 25: S499. DOI: 10.1016/S0197-4580(04)81646-4 |
0.31 |
|
2004 |
Pericak-Vance MA, Bronson P, Martin ER, Browning C, Rayner M, Xu P, Small GW, Roses AD, Schmechel DE, Doraiswamy PM, Welsh-Bohmer KA, Haines JL, Gilbert JR. P4-080 Genetic studies of Alzheimer disease on chromosome 9P Neurobiology of Aging. 25. DOI: 10.1016/S0197-4580(04)81638-5 |
0.318 |
|
2004 |
Browning C, Vance DD, Bronson PG, Schmechel D, Welsh-Bohmer K, Scott W, Haines JL, Vance JM, Pericak-Vance MA. P4-072 Follow-up analysis of chromosome 2 linkage in early-onset Alzheimer disease Neurobiology of Aging. 25. DOI: 10.1016/S0197-4580(04)81630-0 |
0.343 |
|
2004 |
Xu P, Hulette C, Hauser M, Schmechel DE, Pericak-Vance MA, Gilbert JR. O1-03-06 Transcription analysis of APOE specific hippocampus in Alzheimer's disease (AD) using serial analysis of gene expression (SAGE) and long-SAGE Neurobiology of Aging. 25. DOI: 10.1016/S0197-4580(04)80049-6 |
0.373 |
|
2003 |
Kulasingam SL, Samsa GP, Zarin DA, Rutschmann OT, Patwardhan MB, McCrory DC, Schmechel DE, Matchar DB. When should functional neuroimaging techniques be used in the diagnosis and management of Alzheimer's dementia? A decision analysis. Value in Health : the Journal of the International Society For Pharmacoeconomics and Outcomes Research. 6: 542-50. PMID 14627060 DOI: 10.1046/J.1524-4733.2003.65248.X |
0.334 |
|
2003 |
Li YJ, Oliveira SA, Xu P, Martin ER, Stenger JE, Scherzer CR, Hauser MA, Scott WK, Small GW, Nance MA, Watts RL, Hubble JP, Koller WC, Pahwa R, Stern MB, ... ... Schmechel DE, et al. Glutathione S-transferase omega-1 modifies age-at-onset of Alzheimer disease and Parkinson disease. Human Molecular Genetics. 12: 3259-67. PMID 14570706 DOI: 10.1093/Hmg/Ddg357 |
0.394 |
|
2003 |
Scott WK, Hauser ER, Schmechel DE, Welsh-Bohmer KA, Small GW, Roses AD, Saunders AM, Gilbert JR, Vance JM, Haines JL, Pericak-Vance MA. Ordered-subsets linkage analysis detects novel Alzheimer disease loci on chromosomes 2q34 and 15q22. American Journal of Human Genetics. 73: 1041-51. PMID 14564669 DOI: 10.1086/379083 |
0.335 |
|
2003 |
Oliveira SA, Martin ER, Scott WK, Nicodemus KK, Small GW, Schmechel DE, Doraiswamy PM, Roses AD, Saunders AM, Gilbert JR, Haines JL, Vance JM, Pericak-Vance MA. The Q7R Saitohin gene polymorphism is not associated with Alzheimer disease. Neuroscience Letters. 347: 143-6. PMID 12875906 DOI: 10.1016/S0304-3940(03)00670-0 |
0.403 |
|
2003 |
Trembath Y, Rosenberg C, Ervin JF, Schmechel DE, Gaskell P, Pericak-Vance M, Vance J, Hulette CM. Lewy body pathology is a frequent co-pathology in familial Alzheimer's disease. Acta Neuropathologica. 105: 484-8. PMID 12677449 DOI: 10.1007/S00401-003-0670-9 |
0.334 |
|
2002 |
Colton CA, Brown CM, Cook D, Needham LK, Xu Q, Czapiga M, Saunders AM, Schmechel DE, Rasheed K, Vitek MP. APOE and the regulation of microglial nitric oxide production: a link between genetic risk and oxidative stress. Neurobiology of Aging. 23: 777-85. PMID 12392781 DOI: 10.1016/S0197-4580(02)00016-7 |
0.344 |
|
2002 |
Li YJ, Scott WK, Hedges DJ, Zhang F, Gaskell PC, Nance MA, Watts RL, Hubble JP, Koller WC, Pahwa R, Stern MB, Hiner BC, Jankovic J, Allen FA, Goetz CG, ... ... Schmechel DE, et al. Age at onset in two common neurodegenerative diseases is genetically controlled. American Journal of Human Genetics. 70: 985-93. PMID 11875758 DOI: 10.1086/339815 |
0.36 |
|
2001 |
Sullivan P, Schmechel D, Hulette C, Ange R, Alberts MJ. Apolipoprotein E Transgenic Mouse Model of Cerebral Amyloid Angiopathy Stroke. 32: 329-329. DOI: 10.1161/01.Str.32.Suppl_1.329-C |
0.35 |
|
2000 |
Martin ER, Lai EH, Gilbert JR, Rogala AR, Afshari AJ, Riley J, Finch KL, Stevens JF, Livak KJ, Slotterbeck BD, Slifer SH, Warren LL, Conneally PM, Schmechel DE, Purvis I, et al. SNPing away at complex diseases: analysis of single-nucleotide polymorphisms around APOE in Alzheimer disease. American Journal of Human Genetics. 67: 383-94. PMID 10869235 DOI: 10.1086/303003 |
0.365 |
|
2000 |
Martin ER, Gilbert JR, Lai EH, Riley J, Rogala AR, Slotterbeck BD, Sipe CA, Grubber JM, Warren LL, Conneally PM, Saunders AM, Schmechel DE, Purvis I, Pericak-Vance MA, Roses AD, et al. Analysis of association at single nucleotide polymorphisms in the APOE region. Genomics. 63: 7-12. PMID 10662539 DOI: 10.1006/Geno.1999.6057 |
0.319 |
|
2000 |
Hulette CM, Pannell C, Ervin JF, Rosenberg CK, Saunders AM, Strittmatter WJ, Schmechel DE. Vascular abnormalities in APOE4,4 and APOE3,3 Alzheimer's disease Neurobiology of Aging. 21: 271. DOI: 10.1016/S0197-4580(00)83173-5 |
0.352 |
|
2000 |
Sullivan PM, Mace BE, Schmechel DE. Targeted human apoE replacement mice provide a model for studying the role of apoE in Alzheimer's disease Neurobiology of Aging. 21: 18. DOI: 10.1016/S0197-4580(00)82756-6 |
0.356 |
|
1999 |
Hulette CM, Pericak-Vance MA, Roses AD, Schmechel DE, Yamaoka LH, Gaskell PC, Welsh-Bohmer KA, Crowther RA, Spillantini MG. Neuropathological features of frontotemporal dementia and parkinsonism linked to chromosome 17q21-22 (FTDP-17): Duke Family 1684. Journal of Neuropathology and Experimental Neurology. 58: 859-66. PMID 10446810 DOI: 10.1097/00005072-199908000-00008 |
0.383 |
|
1999 |
Rogaeva EA, Premkumar S, Grubber J, Serneels L, Scott WK, Kawarai T, Song Y, Hill DL, Abou-Donia SM, Martin ER, Vance JJ, Yu G, Orlacchio A, Pei Y, Nishimura M, ... ... Schmechel D, et al. An alpha-2-macroglobulin insertion-deletion polymorphism in Alzheimer disease. Nature Genetics. 22: 19-22. PMID 10319855 DOI: 10.1038/8729 |
0.393 |
|
1999 |
Xu PT, Schmechel D, Qiu HL, Herbstreith M, Rothrock-Christian T, Eyster M, Roses AD, Gilbert JR. Sialylated human apolipoprotein E (apoEs) is preferentially associated with neuron-enriched cultures from APOE transgenic mice. Neurobiology of Disease. 6: 63-75. PMID 10078974 DOI: 10.1006/Nbdi.1998.0213 |
0.391 |
|
1999 |
Xu PT, Gilbert JR, Qiu HL, Ervin J, Rothrock-Christian TR, Hulette C, Schmechel DE. Specific regional transcription of apolipoprotein E in human brain neurons. The American Journal of Pathology. 154: 601-11. PMID 10027417 DOI: 10.1016/S0002-9440(10)65305-9 |
0.413 |
|
1998 |
Einstein G, Patel V, Bautista P, Kenna M, Melone L, Fader R, Karson K, Mann S, Saunders AM, Hulette C, Mash D, Roses AD, Schmechel DE. Intraneuronal ApoE in human visual cortical areas reflects the staging of Alzheimer disease pathology. Journal of Neuropathology and Experimental Neurology. 57: 1190-201. PMID 9862642 DOI: 10.1097/00005072-199812000-00011 |
0.433 |
|
1998 |
Xu PT, Gilbert JR, Qiu HL, Rothrock-Christian T, Settles DL, Roses AD, Schmechel DE. Regionally specific neuronal expression of human APOE gene in transgenic mice. Neuroscience Letters. 246: 65-8. PMID 9627181 DOI: 10.1016/S0304-3940(98)00247-X |
0.439 |
|
1998 |
Roses AD, Gilbert J, Xu PT, Sullivan P, Popko B, Burkhart DS, Christian-Rothrock T, Saunders AM, Maeda N, Schmechel DE. Cis-acting human ApoE tissue expression element is associated with human pattern of intraneuronal ApoE in transgenic mice. Neurobiology of Aging. 19: S53-8. PMID 9562469 DOI: 10.1016/S0197-4580(98)00030-X |
0.398 |
|
1998 |
Laskowitz DT, Matthew WD, Bennett ER, Schmechel D, Herbstreith MH, Goel S, McMillian MK. Endogenous apolipoprotein E suppresses LPS-stimulated microglial nitric oxide production. Neuroreport. 9: 615-8. PMID 9559926 DOI: 10.1097/00001756-199803090-00010 |
0.342 |
|
1998 |
Sheng H, Laskowitz DT, Bennett E, Schmechel DE, Bart RD, Saunders AM, Pearlstein RD, Roses AD, Warner DS. Apolipoprotein E isoform-specific differences in outcome from focal ischemia in transgenic mice. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 18: 361-6. PMID 9538900 DOI: 10.1097/00004647-199804000-00003 |
0.338 |
|
1997 |
Piantadosi CA, Zhang J, Levin ED, Folz RJ, Schmechel DE. Apoptosis and delayed neuronal damage after carbon monoxide poisoning in the rat. Experimental Neurology. 147: 103-14. PMID 9294407 DOI: 10.1006/Exnr.1997.6584 |
0.305 |
|
1996 |
Xu PT, Schmechel D, Rothrock-Christian T, Burkhart DS, Qiu HL, Popko B, Sullivan P, Maeda N, Saunders AM, Roses AD, Gilbert JR. Human apolipoprotein E2, E3, and E4 isoform-specific transgenic mice: human-like pattern of glial and neuronal immunoreactivity in central nervous system not observed in wild-type mice. Neurobiology of Disease. 3: 229-45. PMID 8980023 DOI: 10.1006/Nbdi.1996.0023 |
0.384 |
|
1996 |
Lane SC, Jolly RD, Schmechel DE, Alroy J, Boustany RM. Apoptosis as the mechanism of neurodegeneration in Batten's disease. Journal of Neurochemistry. 67: 677-83. PMID 8764595 DOI: 10.1046/J.1471-4159.1996.67020677.X |
0.346 |
|
1996 |
Saunders AM, Hulette O, Welsh-Bohmer KA, Schmechel DE, Crain B, Burke JR, Alberts MJ, Strittmatter WJ, Breitner JC, Rosenberg C. Specificity, sensitivity, and predictive value of apolipoprotein-E genotyping for sporadic Alzheimer's disease. Lancet (London, England). 348: 90-3. PMID 8676723 DOI: 10.1016/S0140-6736(96)01251-2 |
0.382 |
|
1996 |
Roses AD, Einstein G, Gilbert J, Goedert M, Han SH, Huang D, Hulette C, Masliah E, Pericak-Vance MA, Saunders AM, Schmechel DE, Strittmatter WJ, Weisgraber KH, Xi PT. Morphological, biochemical, and genetic support for an apolipoprotein E effect on microtubular metabolism. Annals of the New York Academy of Sciences. 777: 146-57. PMID 8624078 DOI: 10.1111/J.1749-6632.1996.Tb34413.X |
0.419 |
|
1996 |
Stopa E, Vitek M, Rubin B, Schmechel D, Kuo-Leblanc. V, Wei Y, Song P, King J, Boteva K, Mitsuda N, Gilbert J, Roses A. 67 In-situ localization of S182 mRNA in sporadic Alzheimer's disease (AD) Neurobiology of Aging. 17: S17. DOI: 10.1016/S0197-4580(96)80069-8 |
0.362 |
|
1996 |
Roses A, Saunders A, Pericak-Vance M, Einstein G, Hulette C, Schmechel D, Huang D, Strittmatter W. Apolipoprotein is a susceptibility genetic locus that affects the expression of late-onset familial and sporadic Alzheimer's disease Biological Psychiatry. 39: 562. DOI: 10.1016/0006-3223(96)84162-X |
0.352 |
|
1995 |
Roses AD, Saunders AM, Alberts MA, Strittmatter WJ, Schmechel D, Gorder E, Pericak-Vance MA. Apolipoprotein E E4 allele and risk of dementia. Jama. 273: 374-5; author reply . PMID 7823377 DOI: 10.1001/Jama.1995.03520290026015 |
0.376 |
|
1994 |
Roses AD, Pericak-Vance MA, Saunders AM, Schmechel D, Goldgaber D, Strittmatter W. Complex genetic disease: can genetic strategies in Alzheimer's disease and new genetic mechanisms be applied to epilepsy? Epilepsia. 35: S20-8. PMID 8293721 DOI: 10.1111/J.1528-1157.1994.Tb05925.X |
0.334 |
|
1994 |
Han SH, Einstein G, Weisgraber KH, Strittmatter WJ, Saunders AM, Pericak-Vance M, Roses AD, Schmechel DE. Apolipoprotein E is localized to the cytoplasm of human cortical neurons: a light and electron microscopic study. Journal of Neuropathology and Experimental Neurology. 53: 535-44. PMID 8083695 DOI: 10.1097/00005072-199409000-00013 |
0.413 |
|
1994 |
Han SH, Hulette C, Saunders AM, Einstein G, Pericak-Vance M, Strittmatter WJ, Roses AD, Schmechel DE. Apolipoprotein E is present in hippocampal neurons without neurofibrillary tangles in Alzheimer's disease and in age-matched controls. Experimental Neurology. 128: 13-26. PMID 8070517 DOI: 10.1006/Exnr.1994.1108 |
0.454 |
|
1994 |
Strittmatter WJ, Saunders AM, Goedert M, Weisgraber KH, Dong LM, Jakes R, Huang DY, Pericak-Vance M, Schmechel D, Roses AD. Isoform-specific interactions of apolipoprotein E with microtubule-associated protein tau: implications for Alzheimer disease. Proceedings of the National Academy of Sciences of the United States of America. 91: 11183-6. PMID 7972031 DOI: 10.1073/Pnas.91.23.11183 |
0.366 |
|
1994 |
Corder EH, Saunders AM, Risch NJ, Strittmatter WJ, Schmechel DE, Gaskell PC, Rimmler JB, Locke PA, Conneally PM, Schmader KE. Protective effect of apolipoprotein E type 2 allele for late onset Alzheimer disease. Nature Genetics. 7: 180-4. PMID 7920638 DOI: 10.1038/Ng0694-180 |
0.404 |
|
1994 |
Huang DY, Goedert M, Jakes R, Weisgraber KH, Garner CC, Saunders AM, Pericak-Vance MA, Schmechel DE, Roses AD, Strittmatter WJ. Isoform-specific interactions of apolipoprotein E with the microtubule-associated protein MAP2c: implications for Alzheimer's disease. Neuroscience Letters. 182: 55-8. PMID 7891887 DOI: 10.1016/0304-3940(94)90204-6 |
0.374 |
|
1994 |
Roses A, Saunders A, Corder E, Risch N, Haines J, Pericak-Vance M, Han S, Einstein G, Hulette C, Schmechel D, Goedert M, Jakes R, Dong L, Weisgraber K, Holsti M, et al. Apolipoprotein E-e4 and apolipoprotein E-e2 are susceptibility genes that affect the rate of disease expressivity of late-onset familial and sporadic Alzheimer disease Journal of the Neurological Sciences. 127: 2. DOI: 10.1016/0022-510X(94)90109-0 |
0.325 |
|
1993 |
Strittmatter WJ, Saunders AM, Schmechel D, Pericak-Vance M, Enghild J, Salvesen GS, Roses AD. Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease. Proceedings of the National Academy of Sciences of the United States of America. 90: 1977-81. PMID 8446617 DOI: 10.1073/Pnas.90.5.1977 |
0.397 |
|
1993 |
Schmechel DE, Saunders AM, Strittmatter WJ, Crain BJ, Hulette CM, Joo SH, Pericak-Vance MA, Goldgaber D, Roses AD. Increased amyloid beta-peptide deposition in cerebral cortex as a consequence of apolipoprotein E genotype in late-onset Alzheimer disease. Proceedings of the National Academy of Sciences of the United States of America. 90: 9649-53. PMID 8415756 DOI: 10.1073/Pnas.90.20.9649 |
0.382 |
|
1993 |
Saunders AM, Strittmatter WJ, Schmechel D, George-Hyslop PH, Pericak-Vance MA, Joo SH, Rosi BL, Gusella JF, Crapper-MacLachlan DR, Alberts MJ. Association of apolipoprotein E allele epsilon 4 with late-onset familial and sporadic Alzheimer's disease. Neurology. 43: 1467-72. PMID 8350998 DOI: 10.1212/Wnl.43.8.1467 |
0.42 |
|
1993 |
Corder EH, Saunders AM, Strittmatter WJ, Schmechel DE, Gaskell PC, Small GW, Roses AD, Haines JL, Pericak-Vance MA. Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families. Science (New York, N.Y.). 261: 921-3. PMID 8346443 DOI: 10.1126/Science.8346443 |
0.406 |
|
1988 |
Schmechel DE, Goldgaber D, Burkhart DS, Gilbert JR, Gajdusek DC, Roses AD. Cellular localization of messenger RNA encoding amyloid-beta-protein in normal tissue and in Alzheimer disease. Alzheimer Disease and Associated Disorders. 2: 96-111. PMID 3063300 DOI: 10.1097/00002093-198802020-00002 |
0.413 |
|
1987 |
Fitzpatrick D, Lund JS, Schmechel DE, Towles AC. Distribution of GABAergic neurons and axon terminals in the macaque striate cortex. The Journal of Comparative Neurology. 264: 73-91. PMID 3680625 DOI: 10.1002/Cne.902640107 |
0.309 |
|
1987 |
Schmechel DE, Marangos PJ, Martin BM, Winfield S, Burkhart DS, Roses AD, Ginns EI. Localization of neuron-specific enolase (NSE) mRNA in human brain. Neuroscience Letters. 76: 233-8. PMID 3587757 DOI: 10.1016/0304-3940(87)90721-X |
0.377 |
|
1986 |
Lin CS, Lu SM, Schmechel DE. Glutamic acid decarboxylase and somatostatin immunoreactivities in rat visual cortex. The Journal of Comparative Neurology. 244: 369-83. PMID 2870090 DOI: 10.1002/Cne.902440309 |
0.319 |
|
1985 |
Walker LC, Kitt CA, Struble RG, Schmechel DE, Oertel WH, Cork LC, Price DL. Glutamic acid decarboxylase-like immunoreactive neurites in senile plaques. Neuroscience Letters. 59: 165-9. PMID 2997667 DOI: 10.1016/0304-3940(85)90194-6 |
0.331 |
|
1984 |
Fitzpatrick D, Penny GR, Schmechel DE. Glutamic acid decarboxylase-immunoreactive neurons and terminals in the lateral geniculate nucleus of the cat. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 4: 1809-29. PMID 6376726 DOI: 10.1523/Jneurosci.04-07-01809.1984 |
0.32 |
|
1984 |
Elde R, Seybold V, Sorenson RL, Cummings S, Holets V, Onstott D, Sasek C, Schmechel DE, Oertel WH. Peptidergic regulation in neuroendocrine and autonomic systems. Peptides. 5: 101-7. PMID 6148735 DOI: 10.1016/0196-9781(84)90269-9 |
0.316 |
|
1984 |
Schmechel DE, Vickrey BG, Fitzpatrick D, Elde RP. GABAergic neurons of mammalian cerebral cortex: widespread subclass defined by somatostatin content. Neuroscience Letters. 47: 227-32. PMID 6147798 DOI: 10.1016/0304-3940(84)90518-4 |
0.31 |
|
1983 |
Penny GR, Fitzpatrick D, Schmechel DE, Diamond IT. Glutamic acid decarboxylase-immunoreactive neurons and horseradish peroxidase-labeled projection neurons in the ventral posterior nucleus of the cat and Galago senegalensis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 3: 1868-87. PMID 6886749 DOI: 10.1523/Jneurosci.03-09-01868.1983 |
0.322 |
|
1983 |
Kirino T, Brightman MW, Oertel WH, Schmechel DE, Marangos PJ. Neuron-specific enolase as an index of neuronal regeneration and reinnervation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 3: 915-23. PMID 6842284 DOI: 10.1523/Jneurosci.03-05-00915.1983 |
0.306 |
|
1983 |
Oertel WH, Riethmüller G, Mugnaini E, Schmechel DE, Weindl A, Gramsch C, Herz A. Opioid peptide-like immunoreactivity localized in GABAErgic neurons of rat neostriatum and central amygdaloid nucleus. Life Sciences. 33: 73-6. PMID 6664248 DOI: 10.1016/0024-3205(83)90447-2 |
0.324 |
|
1981 |
Oertel WH, Schmechel DE, Mugnaini E, Tappaz ML, Kopin IJ. Immunocytochemical localization of glutamate decarboxylase in rat cerebellum with a new antiserum. Neuroscience. 6: 2715-35. PMID 7033824 DOI: 10.1016/0306-4522(81)90115-9 |
0.314 |
|
1980 |
Schmechel DE, Brightman MW, Barker JL. Localization of neuron-specific enolase in mouse spinal neurons grown in tissue culture. Brain Research. 181: 391-400. PMID 6985809 DOI: 10.1016/0006-8993(80)90621-6 |
0.309 |
|
1980 |
Schmechel DE, Brightman MW, Marangos PJ. Neurons switch from non-neuronal enolase to neuron-specific enolase during differentiation. Brain Research. 190: 195-214. PMID 6769533 DOI: 10.1016/0006-8993(80)91169-5 |
0.333 |
|
1980 |
Marangos PJ, Schmechel DE, Parma AM, Goodwin FK. Developmental profile of neuron-specific (NSE) and non-neuronal (NNE) enolase. Brain Research. 190: 185-93. PMID 6769532 DOI: 10.1016/0006-8993(80)91168-3 |
0.333 |
|
1979 |
Marangos PJ, Schmechel D, Parma AM, Clark RL, Goodwin FK. Measurement of neuron-specific (NSE) and non-neuronal (NNE) isoenzymes of enolase in rat, monkey and human nervous tissue. Journal of Neurochemistry. 33: 319-29. PMID 110910 DOI: 10.1111/J.1471-4159.1979.Tb11735.X |
0.341 |
|
1978 |
Schmechel D, Marangos PJ, Zis AP, Brightman M, Goodwin FK. Brain endolases as specific markers of neuronal and glial cells. Science (New York, N.Y.). 199: 313-5. PMID 339349 DOI: 10.1126/Science.339349 |
0.333 |
|
1978 |
Schmechel D, Marangos PJ, Brightman M. Neurone-specific enolase is a molecular marker for peripheral and central neuroendocrine cells. Nature. 276: 834-6. PMID 31568 DOI: 10.1038/276834A0 |
0.353 |
|
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