Year |
Citation |
Score |
2024 |
Chen TY, Wang FY, Lee PJ, Hsu AL, Ching TT. Mitochondrial S-adenosylmethionine deficiency induces mitochondrial unfolded protein response and extends lifespan in Caenorhabditis elegans. Aging Cell. e14103. PMID 38361361 DOI: 10.1111/acel.14103 |
0.505 |
|
2022 |
Lim CY, Lin HT, Kumsta C, Lu TC, Wang FY, Kang YH, Hansen M, Ching TT, Hsu AL. SAMS-1 coordinates HLH-30/TFEB and PHA-4/FOXA activities through histone methylation to mediate dietary restriction-induced autophagy and longevity. Autophagy. 1-17. PMID 35503435 DOI: 10.1080/15548627.2022.2068267 |
0.541 |
|
2020 |
Chen CC, Lim CY, Lee PJ, Hsu AL, Ching TT. S-adenosyl methionine synthetase SAMS-5 mediates dietary restriction-induced longevity in Caenorhabditis elegans. Plos One. 15: e0241455. PMID 33175851 DOI: 10.1371/journal.pone.0241455 |
0.548 |
|
2020 |
Sural S, Liang CY, Wang FY, Ching TT, Hsu AL. HSB-1/HSF-1 pathway modulates histone H4 in mitochondria to control mtDNA transcription and longevity. Science Advances. 6. PMID 33087356 DOI: 10.1126/sciadv.aaz4452 |
0.538 |
|
2020 |
Lombard DB, Kohler WJ, Guo AH, Gendron C, Han M, Ding W, Lyu Y, Ching TT, Wang FY, Chakraborty TS, Nikolovska-Coleska Z, Duan Y, Girke T, Hsu AL, Pletcher SD, et al. High-throughput small molecule screening reveals Nrf2-dependent and -independent pathways of cellular stress resistance. Science Advances. 6. PMID 33008901 DOI: 10.1126/sciadv.aaz7628 |
0.495 |
|
2020 |
Ching TT, Chen YC, Li G, Liu J, Xu XS, Hsu AL. Short-term enhancement of motor neuron synaptic exocytosis during early aging extends lifespan in . Experimental Biology and Medicine (Maywood, N.J.). 1535370220950639. PMID 32854519 DOI: 10.1177/1535370220950639 |
0.501 |
|
2020 |
Kuo CT, You GT, Jian YJ, Chen TS, Siao YC, Hsu AL, Ching TT. AMPK-mediated formation of stress granules is required for dietary restriction-induced longevity in Caenorhabditis elegans. Aging Cell. e13157. PMID 32432401 DOI: 10.1111/Acel.13157 |
0.577 |
|
2015 |
Yuan Y, Hakimi P, Kao C, Kao A, Liu R, Janocha A, Boyd-Tressler A, Hang X, Alhoraibi H, Slater E, Xia K, Cao P, Shue Q, Ching TT, Hsu AL, et al. Reciprocal changes in phosphoenolpyruvate carboxykinase and pyruvate kinase with age are a determinant of aging in C. elegans. The Journal of Biological Chemistry. PMID 26631730 DOI: 10.1074/Jbc.M115.691766 |
0.535 |
|
2014 |
Kumsta C, Ching TT, Nishimura M, Davis AE, Gelino S, Catan HH, Yu X, Chu CC, Ong B, Panowski SH, Baird N, Bodmer R, Hsu AL, Hansen M. Integrin-linked kinase modulates longevity and thermotolerance in C. elegans through neuronal control of HSF-1. Aging Cell. 13: 419-30. PMID 24314125 DOI: 10.1111/Acel.12189 |
0.574 |
|
2012 |
Yuan Y, Kadiyala CS, Ching TT, Hakimi P, Saha S, Xu H, Yuan C, Mullangi V, Wang L, Fivenson E, Hanson RW, Ewing R, Hsu AL, Miyagi M, Feng Z. Enhanced energy metabolism contributes to the extended life span of calorie-restricted Caenorhabditis elegans. The Journal of Biological Chemistry. 287: 31414-26. PMID 22810224 DOI: 10.1074/Jbc.M112.377275 |
0.488 |
|
2012 |
Chiang WC, Ching TT, Lee HC, Mousigian C, Hsu AL. HSF-1 regulators DDL-1/2 link insulin-like signaling to heat-shock responses and modulation of longevity. Cell. 148: 322-34. PMID 22265419 DOI: 10.1016/j.cell.2011.12.019 |
0.559 |
|
2011 |
Ching TT, Hsu AL. Solid plate-based dietary restriction in Caenorhabditis elegans. Journal of Visualized Experiments : Jove. PMID 21654629 DOI: 10.3791/2701 |
0.514 |
|
2011 |
Ching TT, Chiang WC, Chen CS, Hsu AL. Celecoxib extends C. elegans lifespan via inhibition of insulin-like signaling but not cyclooxygenase-2 activity. Aging Cell. 10: 506-19. PMID 21348927 DOI: 10.1111/j.1474-9726.2011.00688.x |
0.615 |
|
2010 |
Ching TT, Paal AB, Mehta A, Zhong L, Hsu AL. drr-2 encodes an eIF4H that acts downstream of TOR in diet-restriction-induced longevity of C. elegans. Aging Cell. 9: 545-57. PMID 20456299 DOI: 10.1111/j.1474-9726.2010.00580.x |
0.569 |
|
2001 |
Ching TT, Lin HP, Yang CC, Oliveira M, Lu PJ, Chen CS. Specific binding of the C-terminal Src homology 2 domain of the p85alpha subunit of phosphoinositide 3-kinase to phosphatidylinositol 3,4,5-trisphosphate. Localization and engineering of the phosphoinositide-binding motif. The Journal of Biological Chemistry. 276: 43932-8. PMID 11555646 DOI: 10.1074/jbc.M105159200 |
0.41 |
|
2001 |
Ching TT, Hsu AL, Johnson AJ, Chen CS. Phosphoinositide 3-kinase facilitates antigen-stimulated Ca(2+) influx in RBL-2H3 mast cells via a phosphatidylinositol 3,4,5-trisphosphate-sensitive Ca(2+) entry mechanism. The Journal of Biological Chemistry. 276: 14814-20. PMID 11278575 DOI: 10.1074/jbc.M009851200 |
0.606 |
|
2000 |
Wang DS, Ching TT, St Pyrek J, Chen CS. Biotinylated phosphatidylinositol 3,4,5-trisphosphate as affinity ligand. Analytical Biochemistry. 280: 301-7. PMID 10790314 DOI: 10.1006/Abio.2000.4525 |
0.503 |
|
2000 |
Hsu AL, Ching TT, Wang DS, Song X, Rangnekar VM, Chen CS. The cyclooxygenase-2 inhibitor celecoxib induces apoptosis by blocking Akt activation in human prostate cancer cells independently of Bcl-2. The Journal of Biological Chemistry. 275: 11397-403. PMID 10753955 DOI: 10.1074/Jbc.275.15.11397 |
0.643 |
|
2000 |
Hsu AL, Ching TT, Sen G, Wang DS, Bondada S, Authi KS, Chen CS. Novel function of phosphoinositide 3-kinase in T cell Ca2+ signaling. A phosphatidylinositol 3,4,5-trisphosphate-mediated Ca2+ entry mechanism. The Journal of Biological Chemistry. 275: 16242-50. PMID 10748064 DOI: 10.1074/Jbc.M002077200 |
0.607 |
|
1999 |
Ching TT, Wang DS, Hsu AL, Lu PJ, Chen CS. Identification of multiple phosphoinositide-specific phospholipases D as new regulatory enzymes for phosphatidylinositol 3,4, 5-trisphosphate. The Journal of Biological Chemistry. 274: 8611-7. PMID 10085097 |
0.587 |
|
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