Monica M. Montano - Publications

Affiliations: 
Case Western Reserve University School of Medicine, Cleveland, OH, United States 
Area:
Pharmacology, Molecular Biology, Oncology

39 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Sharma V, Joshi J, Yeh IJ, Doughman Y, Blankenberg D, Wald D, Montano MM. Re-Expression of ERα and AR in Receptor Negative Endocrine Cancers GSK3 Inhibition. Frontiers in Oncology. 12: 824594. PMID 35402240 DOI: 10.3389/fonc.2022.824594  0.438
2022 Mozar F, Sharma V, Gorityala S, Albert JM, Xu Y, Montano MM. Downregulation of Dihydrotestosterone and Estradiol Levels by HEXIM1. Endocrinology. 163. PMID 34864989 DOI: 10.1210/endocr/bqab236  0.477
2020 Sharma V, Montano MM. Non-epigenetic induction of HEXIM1 by DNMT1 inhibitors and functional relevance. Scientific Reports. 10: 21015. PMID 33273553 DOI: 10.1038/s41598-020-78058-y  0.474
2019 Montano MM, Yeh IJ, Chen Y, Hernandez C, Kiselar JG, de la Fuente M, Lawes AM, Nieman MT, Kiser PD, Jacobberger J, Exner AA, Lawes MC. Inhibition of the histone demethylase, KDM5B, directly induces re-expression of tumor suppressor protein HEXIM1 in cancer cells. Breast Cancer Research : Bcr. 21: 138. PMID 31805991 DOI: 10.1186/S13058-019-1228-7  0.52
2019 Yeh IJ, Esakov E, Lathia JD, Miyagi M, Reizes O, Montano MM. Phosphorylation of the histone demethylase KDM5B and regulation of the phenotype of triple negative breast cancer. Scientific Reports. 9: 17663. PMID 31776402 DOI: 10.1038/S41598-019-54184-0  0.582
2019 Abd El-Hafeez AA, Khalifa HO, Mahdy EAM, Sharma V, Hosoi T, Ghosh P, Ozawa K, Montano MM, Fujimura T, Ibrahim ARN, Abdelhamid MAA, Pack SP, Shouman SA, Kawamoto S. Anticancer effect of nor-wogonin (5, 7, 8-trihydroxyflavone) on human triple-negative breast cancer cells via downregulation of TAK1, NF-κB, and STAT3. Pharmacological Reports : Pr. 71: 289-298. PMID 30826569 DOI: 10.1016/J.Pharep.2019.01.001  0.584
2018 Abbas SH, Abd El-Hafeez AA, Shoman ME, Montano MM, Hassan HA. New quinoline/chalcone hybrids as anti-cancer agents: Design, synthesis, and evaluations of cytotoxicity and PI3K inhibitory activity. Bioorganic Chemistry. 82: 360-377. PMID 30428415 DOI: 10.1016/J.Bioorg.2018.10.064  0.33
2017 Lama R, Gan C, Idippily N, Bobba V, Danielpour D, Montano M, Su B. HMBA is a putative HSP70 activator stimulating HEXIM1 expression that is down-regulated by estrogen. The Journal of Steroid Biochemistry and Molecular Biology. PMID 28213333 DOI: 10.1016/J.Jsbmb.2017.02.008  0.546
2016 Ketchart W, Yeh IJ, Zhou H, Thiagarajan P, Lathia J, Reizes O, Exner A, Su B, Montano MM. Induction of HEXIM1 activities by HMBA derivative 4a1: Functional consequences and mechanism. Cancer Letters. PMID 27238569 DOI: 10.1016/J.Canlet.2016.05.029  0.487
2015 Krishnamurthy N, Liu L, Xiong X, Zhang J, Montano MM. Downregulation of hPMC2 imparts chemotherapeutic sensitivity to alkylating agents in breast cancer cells. Cancer Biology & Therapy. 16: 518-27. PMID 25849309 DOI: 10.1080/15384047.2015.1016661  0.556
2014 Yeh IJ, Song K, Wittmann BM, Bai X, Danielpour D, Montano MM. HEXIM1 plays a critical role in the inhibition of the androgen receptor by anti-androgens. The Biochemical Journal. 462: 315-27. PMID 24844355 DOI: 10.1042/Bj20140174  0.732
2014 Zhong B, Lama R, Ketchart W, Montano MM, Su B. Lead optimization of HMBA to develop potent HEXIM1 inducers. Bioorganic & Medicinal Chemistry Letters. 24: 1410-3. PMID 24503105 DOI: 10.1016/J.Bmcl.2014.01.025  0.314
2014 Pasupuleti V, Du W, Gupta Y, Yeh IJ, Montano M, Magi-Galuzzi C, Welford SM. Dysregulated D-dopachrome tautomerase, a hypoxia-inducible factor-dependent gene, cooperates with macrophage migration inhibitory factor in renal tumorigenesis. The Journal of Biological Chemistry. 289: 3713-23. PMID 24356968 DOI: 10.1074/Jbc.M113.500694  0.411
2013 Yeh IJ, Ogba N, Bensigner H, Welford SM, Montano MM. HEXIM1 down-regulates hypoxia-inducible factor-1α protein stability. The Biochemical Journal. 456: 195-204. PMID 24015760 DOI: 10.1042/Bj20130592  0.346
2013 Montano MM, Desjardins CL, Doughman YQ, Hsieh YH, Hu Y, Bensinger HM, Wang C, Stelzer JE, Dick TE, Hoit BD, Chandler MP, Yu X, Watanabe M. Inducible re-expression of HEXIM1 causes physiological cardiac hypertrophy in the adult mouse. Cardiovascular Research. 99: 74-82. PMID 23585471 DOI: 10.1093/Cvr/Cvt086  0.316
2013 Ketchart W, Smith KM, Krupka T, Wittmann BM, Hu Y, Rayman PA, Doughman YQ, Albert JM, Bai X, Finke JH, Xu Y, Exner AA, Montano MM. Inhibition of metastasis by HEXIM1 through effects on cell invasion and angiogenesis. Oncogene. 32: 3829-39. PMID 22964639 DOI: 10.1038/Onc.2012.405  0.769
2012 Montano MM, Krishnamurthy N, Sripathy S. TARGETING THE GENOTOXIC EFFECTS OF ESTROGENS. Drug Discovery Today. Disease Mechanisms. 9: e29-e33. PMID 23795205 DOI: 10.1016/J.Ddmec.2012.11.005  0.499
2012 Krishnamurthy N, Hu Y, Siedlak S, Doughman YQ, Watanabe M, Montano MM. Induction of quinone reductase by tamoxifen or DPN protects against mammary tumorigenesis. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 26: 3993-4002. PMID 22700872 DOI: 10.1096/Fj.12-208330  0.612
2011 Smith KM, Ketchart W, Zhou X, Montano MM, Xu Y. Determination of hexamethylene bisacetamide, an antineoplastic compound, in mouse and human plasma by LC-MS/MS. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. 879: 2206-12. PMID 21723208 DOI: 10.1016/J.Jchromb.2011.06.002  0.3
2011 Krishnamurthy N, Ngam CR, Berdis AJ, Montano MM. The exonuclease activity of hPMC2 is required for transcriptional regulation of the QR gene and repair of estrogen-induced abasic sites. Oncogene. 30: 4731-9. PMID 21602889 DOI: 10.1038/Onc.2011.186  0.572
2011 Ketchart W, Ogba N, Kresak A, Albert JM, Pink JJ, Montano MM. HEXIM1 is a critical determinant of the response to tamoxifen. Oncogene. 30: 3563-9. PMID 21423213 DOI: 10.1038/Onc.2011.76  0.61
2010 Bernardo GM, Lozada KL, Miedler JD, Harburg G, Hewitt SC, Mosley JD, Godwin AK, Korach KS, Visvader JE, Kaestner KH, Abdul-Karim FW, Montano MM, Keri RA. FOXA1 is an essential determinant of ERalpha expression and mammary ductal morphogenesis. Development (Cambridge, England). 137: 2045-54. PMID 20501593 DOI: 10.1242/Dev.043299  0.544
2010 Ogba N, Doughman YQ, Chaplin LJ, Hu Y, Gargesha M, Watanabe M, Montano MM. HEXIM1 modulates vascular endothelial growth factor expression and function in breast epithelial cells and mammary gland. Oncogene. 29: 3639-49. PMID 20453883 DOI: 10.1038/Onc.2010.110  0.45
2008 Ogba N, Chaplin LJ, Doughman YQ, Fujinaga K, Montano MM. HEXIM1 regulates 17beta-estradiol/estrogen receptor-alpha-mediated expression of cyclin D1 in mammary cells via modulation of P-TEFb. Cancer Research. 68: 7015-24. PMID 18757415 DOI: 10.1158/0008-5472.Can-08-0814  0.573
2008 Sripathy SP, Chaplin LJ, Gaikwad NW, Rogan EG, Montano MM. hPMC2 is required for recruiting an ERβ coactivator complex to mediate transcriptional upregulation of NQO1 and protection against oxidative DNA damage by tamoxifen Oncogene. 27: 6376-6384. PMID 18663360 DOI: 10.1038/Onc.2008.235  0.464
2008 Montano MM, Doughman YQ, Deng H, Chaplin L, Yang J, Wang N, Zhou Q, Ward NL, Watanabe M. Mutation of the HEXIM1 gene results in defects during heart and vascular development partly through downregulation of vascular endothelial growth factor. Circulation Research. 102: 415-22. PMID 18079413 DOI: 10.1161/Circresaha.107.157859  0.34
2006 Montano MM, Chaplin LJ, Deng H, Mesia-Vela S, Gaikwad N, Zahid M, Rogan E. Protective roles of quinone reductase and tamoxifen against estrogen-induced mammary tumorigenesis. Oncogene. 26: 3587-90. PMID 17160017 DOI: 10.1038/Sj.Onc.1210144  0.598
2005 Wittmann BM, Fujinaga K, Deng H, Ogba N, Montano MM. The breast cell growth inhibitor, estrogen down regulated gene 1, modulates a novel functional interaction between estrogen receptor alpha and transcriptional elongation factor cyclin T1. Oncogene. 24: 5576-88. PMID 15940264 DOI: 10.1038/Sj.Onc.1208728  0.744
2005 Montano MM, Bianco NR, Deng H, Wittmann BM, Chaplin LC, Katzenellenbogen BS. Estrogen receptor regulation of quinone reductase in breast cancer: implications for estrogen-induced breast tumor growth and therapeutic uses of tamoxifen. Frontiers in Bioscience : a Journal and Virtual Library. 10: 1440-61. PMID 15769636 DOI: 10.2741/1630  0.772
2005 Bianco NR, Chaplin LJ, Montano MM. Differential induction of quinone reductase by phytoestrogens and protection against oestrogen-induced DNA damage. The Biochemical Journal. 385: 279-87. PMID 15456407 DOI: 10.1042/Bj20040959  0.775
2004 Montano MM, Deng H, Liu M, Sun X, Singal R. Transcriptional regulation by the estrogen receptor of antioxidative stress enzymes and its functional implications. Oncogene. 23: 2442-53. PMID 14676828 DOI: 10.1038/Sj.Onc.1207358  0.538
2003 Wittmann BM, Wang N, Montano MM. Identification of a novel inhibitor of breast cell growth that is down-regulated by estrogens and decreased in breast tumors. Cancer Research. 63: 5151-8. PMID 12941847  0.789
2003 Bianco NR, Perry G, Smith MA, Templeton DJ, Montano MM. Functional implications of antiestrogen induction of quinone reductase: inhibition of estrogen-induced deoxyribonucleic acid damage. Molecular Endocrinology (Baltimore, Md.). 17: 1344-55. PMID 12714703 DOI: 10.1210/Me.2002-0382  0.775
2002 Bianco NR, Montano MM. Regulation of prothymosin alpha by estrogen receptor alpha: molecular mechanisms and relevance in estrogen-mediated breast cell growth. Oncogene. 21: 5233-44. PMID 12149645 DOI: 10.1038/Sj.Onc.1205645  0.792
2002 Bianco NR, Montano MM. Erratum: Regulation of prothymosin α by estrogen receptor α: Molecular mechanisms and relevance in estrogen-mediated breast cell growth (Oncogne (2002) 21 (5233-5244)) Oncogene. 21. DOI: 10.1038/Sj.Onc.1205995  0.733
2000 Montano MM, Wittmann BM, Bianco NR. Identification and characterization of a novel factor that regulates quinone reductase gene transcriptional activity. The Journal of Biological Chemistry. 275: 34306-13. PMID 10908561 DOI: 10.1074/Jbc.M003880200  0.76
1998 Montano MM, Jaiswal AK, Katzenellenbogen BS. Transcriptional regulation of the human quinone reductase gene by antiestrogen-liganded estrogen receptor-α and estrogen receptor-β Journal of Biological Chemistry. 273: 25443-25449. PMID 9738013 DOI: 10.1074/Jbc.273.39.25443  0.528
1995 Katzenellenbogen BS, Montano MM, Le Goff P, Schodin DJ, Kraus WL, Bhardwaj B, Fujimoto N. Antiestrogens: mechanisms and actions in target cells. The Journal of Steroid Biochemistry and Molecular Biology. 53: 387-93. PMID 7626486 DOI: 10.1016/0960-0760(95)00084-D  0.441
1995 Nicholson RI, Gee JM, Manning DL, Wakeling AE, Montano MM, Katzenellenbogen BS. Responses to pure antiestrogens (ICI 164384, ICI 182780) in estrogen-sensitive and -resistant experimental and clinical breast cancer. Annals of the New York Academy of Sciences. 761: 148-63. PMID 7625718 DOI: 10.1111/J.1749-6632.1995.Tb31376.X  0.404
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