| Year | Citation | Score | |||
|---|---|---|---|---|---|
| 2020 | Dutta K, Thammisetty SS, Boutej H, Bareil C, Julien JP. Mitigation of ALS pathology by neuron-specific inhibition of nuclear factor kappa B signaling. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 32457070 DOI: 10.1523/Jneurosci.0536-20.2020 | 0.325 | |||
| 2016 | Dutta K, Patel P, Rahimian R, Phaneuf D, Julien JP. Withania somnifera Reverses Transactive Response DNA Binding Protein 43 Proteinopathy in a Mouse Model of Amyotrophic Lateral Sclerosis/Frontotemporal Lobar Degeneration. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. PMID 27928708 DOI: 10.1007/S13311-016-0499-2 | 0.318 | |||
| 2006 | Millecamps S, Robertson J, Lariviere R, Mallet J, Julien JP. Defective axonal transport of neurofilament proteins in neurons overexpressing peripherin. Journal of Neurochemistry. 98: 926-38. PMID 16787413 DOI: 10.1111/J.1471-4159.2006.03932.X | 0.321 | |||
| 2006 | Sasaki T, Gotow T, Shiozaki M, Sakaue F, Saito T, Julien JP, Uchiyama Y, Hisanaga S. Aggregate formation and phosphorylation of neurofilament-L Pro22 Charcot-Marie-Tooth disease mutants. Human Molecular Genetics. 15: 943-52. PMID 16452125 DOI: 10.1093/Hmg/Ddl011 | 0.31 | |||
| 2006 | Veglianese P, Lo Coco D, Bao Cutrona M, Magnoni R, Pennacchini D, Pozzi B, Gowing G, Julien JP, Tortarolo M, Bendotti C. Activation of the p38MAPK cascade is associated with upregulation of TNF alpha receptors in the spinal motor neurons of mouse models of familial ALS. Molecular and Cellular Neurosciences. 31: 218-31. PMID 16219474 DOI: 10.1016/j.mcn.2005.09.009 | 0.303 | |||
| 2005 | Kriz J, Beaulieu JM, Julien JP, Krnjević K. Up-regulation of peripherin is associated with alterations in synaptic plasticity in CA1 and CA3 regions of hippocampus. Neurobiology of Disease. 18: 409-20. PMID 15686970 DOI: 10.1016/J.Nbd.2004.10.009 | 0.475 | |||
| 2004 | Nguyen MD, Shu T, Sanada K, Larivière RC, Tseng HC, Park SK, Julien JP, Tsai LH. A NUDEL-dependent mechanism of neurofilament assembly regulates the integrity of CNS neurons. Nature Cell Biology. 6: 595-608. PMID 15208636 DOI: 10.1038/Ncb1139 | 0.318 | |||
| 2004 | Zhang G, Spencer PH, Jin LQ, Cohlberg JA, Beaulieu JM, Julien JP, Selzer ME. The single neurofilament subunit of lamprey may need another element for filament assembly. The Journal of Comparative Neurology. 471: 188-200. PMID 14986312 DOI: 10.1002/Cne.20026 | 0.515 | |||
| 2004 | Lariviere RC, Julien JP. Functions of intermediate filaments in neuronal development and disease. Journal of Neurobiology. 58: 131-48. PMID 14598376 DOI: 10.1002/Neu.10270 | 0.374 | |||
| 2003 | Larivière RC, Beaulieu JM, Nguyen MD, Julien JP. Peripherin is not a contributing factor to motor neuron disease in a mouse model of amyotrophic lateral sclerosis caused by mutant superoxide dismutase. Neurobiology of Disease. 13: 158-66. PMID 12828939 DOI: 10.1016/S0969-9961(03)00036-6 | 0.563 | |||
| 2003 | Nguyen MD, Boudreau M, Kriz J, Couillard-Després S, Kaplan DR, Julien JP. Cell cycle regulators in the neuronal death pathway of amyotrophic lateral sclerosis caused by mutant superoxide dismutase 1. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 2131-40. PMID 12657672 DOI: 10.1523/Jneurosci.23-06-02131.2003 | 0.331 | |||
| 2003 | Robertson J, Doroudchi MM, Nguyen MD, Durham HD, Strong MJ, Shaw G, Julien JP, Mushynski WE. A neurotoxic peripherin splice variant in a mouse model of ALS. The Journal of Cell Biology. 160: 939-49. PMID 12642616 DOI: 10.1083/Jcb.200205027 | 0.647 | |||
| 2003 | Beaulieu JM, Julien JP. Peripherin-mediated death of motor neurons rescued by overexpression of neurofilament NF-H proteins. Journal of Neurochemistry. 85: 248-56. PMID 12641746 DOI: 10.1046/J.1471-4159.2003.01653.X | 0.599 | |||
| 2002 | Robertson J, Kriz J, Nguyen MD, Julien JP. Pathways to motor neuron degeneration in transgenic mouse models. Biochimie. 84: 1151-60. PMID 12595144 DOI: 10.1016/S0300-9084(02)00025-1 | 0.343 | |||
| 2002 | Nguyen MD, Mushynski WE, Julien JP. Cycling at the interface between neurodevelopment and neurodegeneration. Cell Death and Differentiation. 9: 1294-306. PMID 12478466 DOI: 10.1038/Sj.Cdd.4401108 | 0.62 | |||
| 2002 | Beaulieu JM, Kriz J, Julien JP. Induction of peripherin expression in subsets of brain neurons after lesion injury or cerebral ischemia. Brain Research. 946: 153-61. PMID 12137917 DOI: 10.1016/S0006-8993(02)02830-5 | 0.526 | |||
| 2002 | Zhang Z, Casey DM, Julien JP, Xu Z. Normal dendritic arborization in spinal motoneurons requires neurofilament subunit L. The Journal of Comparative Neurology. 450: 144-52. PMID 12124759 DOI: 10.1002/Cne.10306 | 0.307 | |||
| 2001 | Robertson J, Beaulieu JM, Doroudchi MM, Durham HD, Julien JP, Mushynski WE. Apoptotic death of neurons exhibiting peripherin aggregates is mediated by the proinflammatory cytokine tumor necrosis factor-alpha. The Journal of Cell Biology. 155: 217-26. PMID 11604419 DOI: 10.1083/Jcb.200107058 | 0.687 | |||
| 2001 | Nguyen MD, Larivière RC, Julien JP. Deregulation of Cdk5 in a mouse model of ALS: toxicity alleviated by perikaryal neurofilament inclusions. Neuron. 30: 135-47. PMID 11343650 DOI: 10.1016/S0896-6273(01)00268-9 | 0.369 | |||
| 2000 | Julien JP, Beaulieu JM. Cytoskeletal abnormalities in amyotrophic lateral sclerosis: beneficial or detrimental effects? Journal of the Neurological Sciences. 180: 7-14. PMID 11090858 DOI: 10.1016/S0022-510X(00)00422-6 | 0.593 | |||
| 2000 | Nguyen MD, Larivière RC, Julien JP. Reduction of axonal caliber does not alleviate motor neuron disease caused by mutant superoxide dismutase 1. Proceedings of the National Academy of Sciences of the United States of America. 97: 12306-11. PMID 11050249 DOI: 10.1073/Pnas.97.22.12306 | 0.323 | |||
| 2000 | Couillard-Després S, Meier J, Julien JP. Extra axonal neurofilaments do not exacerbate disease caused by mutant Cu,Zn superoxide dismutase. Neurobiology of Disease. 7: 462-70. PMID 10964615 DOI: 10.1006/Nbdi.2000.0296 | 0.304 | |||
| 2000 | Beaulieu JM, Jacomy H, Julien JP. Formation of intermediate filament protein aggregates with disparate effects in two transgenic mouse models lacking the neurofilament light subunit. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 5321-8. PMID 10884316 | 0.583 | |||
| 1999 | Beaulieu JM, Nguyen MD, Julien JP. Late onset of motor neurons in mice overexpressing wild-type peripherin. The Journal of Cell Biology. 147: 531-44. PMID 15132161 DOI: 10.1083/Jcb.147.3.531 | 0.568 | |||
| 1999 | Meier J, Couillard-Després S, Jacomy H, Gravel C, Julien JP. Extra neurofilament NF-L subunits rescue motor neuron disease caused by overexpression of the human NF-H gene in mice. Journal of Neuropathology and Experimental Neurology. 58: 1099-110. PMID 10515233 DOI: 10.1097/00005072-199910000-00009 | 0.349 | |||
| 1999 | Julien JP. Neurofilament functions in health and disease. Current Opinion in Neurobiology. 9: 554-60. PMID 10508735 DOI: 10.1016/S0959-4388(99)00004-5 | 0.309 | |||
| 1999 | Jacomy H, Zhu Q, Couillard-Després S, Beaulieu JM, Julien JP. Disruption of type IV intermediate filament network in mice lacking the neurofilament medium and heavy subunits. Journal of Neurochemistry. 73: 972-84. PMID 10461886 DOI: 10.1046/J.1471-4159.1999.0730972.X | 0.552 | |||
| 1999 | Yang Y, Bauer C, Strasser G, Wollman R, Julien JP, Fuchs E. Integrators of the cytoskeleton that stabilize microtubules. Cell. 98: 229-38. PMID 10428034 DOI: 10.1016/S0092-8674(00)81017-X | 0.301 | |||
| 1999 | Beaulieu JM, Robertson J, Julien JP. Interactions between peripherin and neurofilaments in cultured cells: disruption of peripherin assembly by the NF-M and NF-H subunits. Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire. 77: 41-5. PMID 10426285 DOI: 10.1139/bcb-77-1-41 | 0.539 | |||
| 1998 | Julien JP, Couillard-Després S, Meier J. Transgenic mice in the study of ALS: the role of neurofilaments. Brain Pathology (Zurich, Switzerland). 8: 759-69. PMID 9804382 DOI: 10.1111/J.1750-3639.1998.Tb00199.X | 0.354 | |||
| 1998 | Zhu Q, Lindenbaum M, Levavasseur F, Jacomy H, Julien JP. Disruption of the NF-H gene increases axonal microtubule content and velocity of neurofilament transport: relief of axonopathy resulting from the toxin beta,beta'-iminodipropionitrile. The Journal of Cell Biology. 143: 183-93. PMID 9763430 DOI: 10.1083/Jcb.143.1.183 | 0.312 | |||
| 1998 | Julien JP, Mushynski WE. Neurofilaments in health and disease. Progress in Nucleic Acid Research and Molecular Biology. 61: 1-23. PMID 9752717 DOI: 10.1016/S0079-6603(08)60823-5 | 0.651 | |||
| 1998 | Williamson TL, Bruijn LI, Zhu Q, Anderson KL, Anderson SD, Julien JP, Cleveland DW. Absence of neurofilaments reduces the selective vulnerability of motor neurons and slows disease caused by a familial amyotrophic lateral sclerosis-linked superoxide dismutase 1 mutant. Proceedings of the National Academy of Sciences of the United States of America. 95: 9631-6. PMID 9689132 DOI: 10.1073/Pnas.95.16.9631 | 0.327 | |||
| 1998 | Couillard-Després S, Zhu Q, Wong PC, Price DL, Cleveland DW, Julien JP. Protective effect of neurofilament heavy gene overexpression in motor neuron disease induced by mutant superoxide dismutase. Proceedings of the National Academy of Sciences of the United States of America. 95: 9626-30. PMID 9689131 DOI: 10.1073/Pnas.95.16.9626 | 0.333 | |||
| 1997 | Tu PH, Gurney ME, Julien JP, Lee VM, Trojanowski JQ. Oxidative stress, mutant SOD1, and neurofilament pathology in transgenic mouse models of human motor neuron disease. Laboratory Investigation; a Journal of Technical Methods and Pathology. 76: 441-56. PMID 9111507 | 0.323 | |||
| 1995 | Julien JP. A role for neurofilaments in the pathogenesis of amyotrophic lateral sclerosis. Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire. 73: 593-7. PMID 8714677 DOI: 10.1139/O95-064 | 0.334 | |||
| 1995 | Charron G, Guy LG, Bazinet M, Julien JP. Multiple neuron-specific enhancers in the gene coding for the human neurofilament light chain. The Journal of Biological Chemistry. 270: 30604-10. PMID 8530496 DOI: 10.1074/Jbc.270.51.30604 | 0.307 | |||
| 1995 | Julien JP, Côté F, Collard JF. Mice overexpressing the human neurofilament heavy gene as a model of ALS. Neurobiology of Aging. 16: 487-90; discussion 4. PMID 7566355 DOI: 10.1016/0197-4580(94)00170-6 | 0.359 | |||
| 1988 | Julien JP, Côté F, Beaudet L, Sidky M, Flavell D, Grosveld F, Mushynski W. Sequence and structure of the mouse gene coding for the largest neurofilament subunit. Gene. 68: 307-14. PMID 3220257 DOI: 10.1016/0378-1119(88)90033-9 | 0.679 | |||
| 1987 | Hurst J, Flavell D, Julien JP, Meijer D, Mushynski W, Grosveld F. The human neurofilament gene (NEFL) is located on the short arm of chromosome 8. Cytogenetics and Cell Genetics. 45: 30-2. PMID 3036423 DOI: 10.1159/000132421 | 0.623 | |||
| 1987 | Julien JP, Grosveld F, Yazdanbaksh K, Flavell D, Meijer D, Mushynski W. The structure of a human neurofilament gene (NF-L): a unique exon-intron organization in the intermediate filament gene family. Biochimica Et Biophysica Acta. 909: 10-20. PMID 3034332 DOI: 10.1016/0167-4781(87)90041-8 | 0.663 | |||
| 1987 | Julien JP, Tretjakoff I, Beaudet L, Peterson A. Expression and assembly of a human neurofilament protein in transgenic mice provide a novel neuronal marking system. Genes & Development. 1: 1085-95. PMID 2828164 DOI: 10.1101/GAD.1.10.1085 | 0.311 | |||
| 1986 | Liesi P, Julien JP, Vilja P, Grosveld F, Rechardt L. Specific detection of neuronal cell bodies: in situ hybridization with a biotin-labeled neurofilament cDNA probe. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 34: 923-6. PMID 3458811 DOI: 10.1177/34.7.3458811 | 0.468 | |||
| 1986 | Julien JP, Meyer D, Flavell D, Hurst J, Grosveld F. Cloning and developmental expression of the murine neurofilament gene family. Brain Research. 387: 243-50. PMID 3103856 DOI: 10.1016/0169-328X(86)90030-6 | 0.488 | |||
| 1985 | Julien JP, Ramachandran K, Grosveld F. Cloning of a cDNA encoding the smallest neurofilament protein from the rat. Biochimica Et Biophysica Acta. 825: 398-404. PMID 3925999 DOI: 10.1016/0167-4781(85)90067-3 | 0.448 | |||
| 1983 | Julien JP, Smoluk GD, Mushynski WE. Characteristics of the protein kinase activity associated with rat neurofilament preparations. Biochimica Et Biophysica Acta. 755: 25-31. PMID 6681714 DOI: 10.1016/0304-4165(83)90268-4 | 0.614 | |||
| 1983 | Julien JP, Mushynski WE. The distribution of phosphorylation sites among identified proteolytic fragments of mammalian neurofilaments. The Journal of Biological Chemistry. 258: 4019-25. PMID 6339492 | 0.598 | |||
| 1982 | Julien JP, Mushynski WE. Multiple phosphorylation sites in mammalian neurofilament polypeptides. The Journal of Biological Chemistry. 257: 10467-70. PMID 7202005 | 0.594 | |||
| 1981 | Julien JP, Mushynski WE. A comparison of in vitro- and in vivo-phosphorylated neurofilament polypeptides. Journal of Neurochemistry. 37: 1579-85. PMID 7199562 DOI: 10.1111/J.1471-4159.1981.Tb06330.X | 0.597 | |||
| 1981 | Julien JP, Mushynski WE, Duncan ID, Griffiths IR. Giant axonal neuropathy: neurofilaments isolated from diseased dogs have a normal polypeptide composition. Experimental Neurology. 72: 619-27. PMID 7195344 DOI: 10.1016/0014-4886(81)90010-8 | 0.589 | |||
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