| Year |
Citation |
Score |
| 2023 |
Araujo VG, Dias MS, Hauswirth WW, Linden R, Petrs-Silva H. rAAV-compatible human mini promoters enhance transgene expression in rat retinal ganglion cells. Experimental Eye Research. 239: 109758. PMID 38123011 DOI: 10.1016/j.exer.2023.109758 |
0.485 |
|
| 2022 |
Lani-Louzada R, Marra C, Dias MS, de Araújo VG, Abreu CA, Ribas VT, Adesse D, Allodi S, Chiodo V, Hauswirth W, Petrs-Silva H, Linden R. Neuroprotective Gene Therapy by Overexpression of the Transcription Factor MAX in Rat Models of Glaucomatous Neurodegeneration. Investigative Ophthalmology & Visual Science. 63: 5. PMID 35103748 DOI: 10.1167/iovs.63.2.5 |
0.46 |
|
| 2019 |
Dias MS, Araujo VG, Vasconcelos T, Li Q, Hauswirth WW, Linden R, Petrs-Silva H. Retina transduction by rAAV2 after intravitreal injection: comparison between mouse and rat. Gene Therapy. PMID 31562387 DOI: 10.1038/S41434-019-0100-9 |
0.449 |
|
| 2018 |
Agúndez L, Zárate-Pérez F, Meier AF, Bardelli M, Llosa M, Escalante CR, Linden RM, Henckaerts E. Exchange of functional domains between a bacterial conjugative relaxase and the integrase of the human adeno-associated virus. Plos One. 13: e0200841. PMID 30016371 DOI: 10.1371/Journal.Pone.0200841 |
0.365 |
|
| 2018 |
Tordo J, O'Leary C, Antunes ASLM, Palomar N, Aldrin-Kirk P, Basche M, Bennett A, D'Souza Z, Gleitz H, Godwin A, Holley RJ, Parker H, Liao AY, Rouse P, Youshani AS, ... ... Linden RM, et al. A novel adeno-associated virus capsid with enhanced neurotropism corrects a lysosomal transmembrane enzyme deficiency. Brain : a Journal of Neurology. PMID 29788236 DOI: 10.1093/Brain/Awy126 |
0.423 |
|
| 2018 |
Smith-Moore S, Neil SJD, Fraefel C, Linden RM, Bollen M, Rowe HM, Henckaerts E. Adeno-associated virus Rep proteins antagonize phosphatase PP1 to counteract KAP1 repression of the latent viral genome. Proceedings of the National Academy of Sciences of the United States of America. PMID 29581310 DOI: 10.1073/Pnas.1721883115 |
0.487 |
|
| 2017 |
Cabral-Miranda F, Nicoloso-Simões E, Adão-Novaes J, Chiodo V, Hauswirth WW, Linden R, Chiarini LB, Petrs-Silva H. rAAV8-733-Mediated Gene Transfer of CHIP/Stub-1 Prevents Hippocampal Neuronal Death in Experimental Brain Ischemia. Molecular Therapy : the Journal of the American Society of Gene Therapy. 25: 392-400. PMID 28153090 DOI: 10.1016/J.Ymthe.2016.11.017 |
0.444 |
|
| 2017 |
Seyffert M, Glauser DL, Schraner EM, de Oliveira AP, Mansilla-Soto J, Vogt B, Büning H, Linden RM, Ackermann M, Fraefel C. Novel Mutant AAV2 Rep Proteins Support AAV2 Replication without Blocking HSV-1 Helpervirus Replication. Plos One. 12: e0170908. PMID 28125695 DOI: 10.1371/Journal.Pone.0170908 |
0.487 |
|
| 2016 |
Bardelli M, Zárate-Pérez F, Agúndez L, Linden RM, Escalante CR, Henckaerts E. Identification of a functionally relevant AAV Rep68 oligomeric interface. Journal of Virology. PMID 27170758 DOI: 10.1128/Jvi.00356-16 |
0.396 |
|
| 2015 |
Petri K, Gabriel R, Agundez L, Fronza R, Afzal S, Kaeppel C, Linden RM, Henckaerts E, Schmidt M. Presence of a trs-Like Motif Promotes Rep-Mediated Wild-Type Adeno-Associated Virus Type 2 Integration. Journal of Virology. 89: 7428-32. PMID 25972561 DOI: 10.1128/Jvi.00426-15 |
0.442 |
|
| 2014 |
Cabral Miranda F, Adão-Novaes J, Hauswirth WW, Linden R, Petrs-Silva H, Chiarini LB. CHIP, a carboxy terminus HSP-70 interacting protein, prevents cell death induced by endoplasmic reticulum stress in the central nervous system. Frontiers in Cellular Neuroscience. 8: 438. PMID 25620910 DOI: 10.3389/Fncel.2014.00438 |
0.388 |
|
| 2014 |
Dutheil N, Smith SC, Agúndez L, Vincent-Mistiaen ZI, Escalante CR, Linden RM, Henckaerts E. Adeno-associated virus Rep represses the human integration site promoter by two pathways that are similar to those required for the regulation of the viral p5 promoter. Journal of Virology. 88: 8227-41. PMID 24829354 DOI: 10.1128/Jvi.00412-14 |
0.506 |
|
| 2014 |
Petri K, Fronza R, Gabriel R, Käppel C, Nowrouzi A, Linden RM, Henckaerts E, Schmidt M. Comparative next-generation sequencing of adeno-associated virus inverted terminal repeats. Biotechniques. 56: 269-73. PMID 24806228 DOI: 10.2144/000114170 |
0.306 |
|
| 2013 |
Petrs-Silva H, Linden R. Advances in recombinant adeno-associated viral vectors for gene delivery. Current Gene Therapy. 13: 335-45. PMID 24060313 DOI: 10.2174/15665232113136660028 |
0.305 |
|
| 2013 |
González-Prieto C, Agúndez L, Linden RM, Llosa M. HUH site-specific recombinases for targeted modification of the human genome. Trends in Biotechnology. 31: 305-12. PMID 23545167 DOI: 10.1016/j.tibtech.2013.02.002 |
0.396 |
|
| 2013 |
Zarate-Perez F, Mansilla-Soto J, Bardelli M, Burgner JW, Villamil-Jarauta M, Kekilli D, Samso M, Linden RM, Escalante CR. Oligomeric properties of adeno-associated virus Rep68 reflect its multifunctionality. Journal of Virology. 87: 1232-41. PMID 23152528 DOI: 10.1128/Jvi.02441-12 |
0.388 |
|
| 2012 |
Kohlbrenner E, Henckaerts E, Rapti K, Gordon RE, Linden RM, Hajjar RJ, Weber T. Quantification of AAV particle titers by infrared fluorescence scanning of coomassie-stained sodium dodecyl sulfate-polyacrylamide gels. Human Gene Therapy Methods. 23: 198-203. PMID 22816378 DOI: 10.1089/Hgtb.2012.049 |
0.393 |
|
| 2012 |
Zarate-Perez F, Bardelli M, Burgner JW, Villamil-Jarauta M, Das K, Kekilli D, Mansilla-Soto J, Linden RM, Escalante CR. The interdomain linker of AAV-2 Rep68 is an integral part of its oligomerization domain: role of a conserved SF3 helicase residue in oligomerization. Plos Pathogens. 8: e1002764. PMID 22719256 DOI: 10.1371/Journal.Ppat.1002764 |
0.36 |
|
| 2011 |
Weitzman MD, Linden RM. Adeno-associated virus biology. Methods in Molecular Biology (Clifton, N.J.). 807: 1-23. PMID 22034024 DOI: 10.1007/978-1-61779-370-7_1 |
0.473 |
|
| 2010 |
Henckaerts E, Linden RM. Adeno-associated virus: a key to the human genome? Future Virology. 5: 555-574. PMID 21212830 DOI: 10.2217/Fvl.10.48 |
0.475 |
|
| 2010 |
Wang X, Blanchard J, Kohlbrenner E, Clement N, Linden RM, Radu A, Grundke-Iqbal I, Iqbal K. The carboxy-terminal fragment of inhibitor-2 of protein phosphatase-2A induces Alzheimer disease pathology and cognitive impairment. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 24: 4420-32. PMID 20651003 DOI: 10.1096/Fj.10-158477 |
0.304 |
|
| 2010 |
Linden RM, Berns KI. Viral Vectors for Gene Therapy Topley and Wilson's Microbiology and Microbial Infections. DOI: 10.1002/9780470688618.Taw0274 |
0.643 |
|
| 2009 |
Dutheil N, Henckaerts E, Kohlbrenner E, Linden RM. Transcriptional analysis of the adeno-associated virus integration site. Journal of Virology. 83: 12512-25. PMID 19759129 DOI: 10.1128/Jvi.01754-09 |
0.459 |
|
| 2009 |
Mansilla-Soto J, Yoon-Robarts M, Rice WJ, Arya S, Escalante CR, Linden RM. DNA structure modulates the oligomerization properties of the AAV initiator protein Rep68. Plos Pathogens. 5: e1000513. PMID 19593381 DOI: 10.1371/Journal.Ppat.1000513 |
0.427 |
|
| 2009 |
Henckaerts E, Dutheil N, Zeltner N, Kattman S, Kohlbrenner E, Ward P, Clément N, Rebollo P, Kennedy M, Keller GM, Linden RM. Site-specific integration of adeno-associated virus involves partial duplication of the target locus. Proceedings of the National Academy of Sciences of the United States of America. 106: 7571-6. PMID 19372372 DOI: 10.1073/Pnas.0806821106 |
0.466 |
|
| 2007 |
Ward P, Clément N, Linden RM. cis effects in adeno-associated virus type 2 replication. Journal of Virology. 81: 9976-89. PMID 17626079 DOI: 10.1128/Jvi.00630-07 |
0.476 |
|
| 2007 |
Hirosue S, Senn K, Clément N, Nonnenmacher M, Gigout L, Linden RM, Weber T. Effect of inhibition of dynein function and microtubule-altering drugs on AAV2 transduction. Virology. 367: 10-8. PMID 17588632 DOI: 10.1016/J.Virol.2007.05.009 |
0.341 |
|
| 2007 |
Glauser DL, Strasser R, Laimbacher AS, Saydam O, Clément N, Linden RM, Ackermann M, Fraefel C. Live covisualization of competing adeno-associated virus and herpes simplex virus type 1 DNA replication: molecular mechanisms of interaction. Journal of Virology. 81: 4732-43. PMID 17314170 DOI: 10.1128/Jvi.02476-06 |
0.47 |
|
| 2006 |
Vasileva A, Linden RM, Jessberger R. Homologous recombination is required for AAV-mediated gene targeting. Nucleic Acids Research. 34: 3345-60. PMID 16822856 DOI: 10.1093/Nar/Gkl455 |
0.409 |
|
| 2005 |
Zhang N, Clément N, Chen D, Fu S, Zhang H, Rebollo P, Linden RM, Bromberg JS. Transduction of pancreatic islets with pseudotyped adeno-associated virus: effect of viral capsid and genome conversion. Transplantation. 80: 683-90. PMID 16177645 DOI: 10.1097/01.Tp.0000173381.97556.0D |
0.435 |
|
| 2005 |
Glauser DL, Saydam O, Balsiger NA, Heid I, Linden RM, Ackermann M, Fraefel C. Four-dimensional visualization of the simultaneous activity of alternative adeno-associated virus replication origins. Journal of Virology. 79: 12218-30. PMID 16160148 DOI: 10.1128/Jvi.79.19.12218-12230.2005 |
0.483 |
|
| 2005 |
Gigout L, Rebollo P, Clement N, Warrington KH, Muzyczka N, Linden RM, Weber T. Altering AAV tropism with mosaic viral capsids. Molecular Therapy : the Journal of the American Society of Gene Therapy. 11: 856-65. PMID 15922956 DOI: 10.1016/J.Ymthe.2005.03.005 |
0.409 |
|
| 2005 |
Petrs-Silva H, Chiodo V, Chiarini LB, Hauswirth WW, Linden R. Modulation of the expression of the transcription factor Max in rat retinal ganglion cells by a recombinant adeno-associated viral vector. Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas MéDicas E BiolóGicas / Sociedade Brasileira De BiofíSica ... [Et Al.]. 38: 375-9. PMID 15761617 DOI: 10.1590/S0100-879X2005000300008 |
0.467 |
|
| 2005 |
Henckaerts E, Zeltner N, Kattman S, Dutheil N, Ward P, Kennedy M, Clement N, Rebollo P, Keller G, Linden RM. 20. Targeted Gene Delivery to Embryonic Stem Cells Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.06.023 |
0.391 |
|
| 2004 |
Yoon-Robarts M, Blouin AG, Bleker S, Kleinschmidt JA, Aggarwal AK, Escalante CR, Linden RM. Residues within the B' motif are critical for DNA binding by the superfamily 3 helicase Rep40 of adeno-associated virus type 2. The Journal of Biological Chemistry. 279: 50472-81. PMID 15371437 DOI: 10.1074/Jbc.M403900200 |
0.383 |
|
| 2004 |
James JA, Aggarwal AK, Linden RM, Escalante CR. Structure of adeno-associated virus type 2 Rep40-ADP complex: insight into nucleotide recognition and catalysis by superfamily 3 helicases. Proceedings of the National Academy of Sciences of the United States of America. 101: 12455-60. PMID 15310852 DOI: 10.1073/Pnas.0403454101 |
0.334 |
|
| 2004 |
Dutheil N, Yoon-Robarts M, Ward P, Henckaerts E, Skrabanek L, Berns KI, Campagne F, Linden RM. Characterization of the mouse adeno-associated virus AAVS1 ortholog. Journal of Virology. 78: 8917-21. PMID 15280500 DOI: 10.1128/Jvi.78.16.8917-8921.2004 |
0.687 |
|
| 2003 |
Ward P, Elias P, Linden RM. Rescue of the adeno-associated virus genome from a plasmid vector: evidence for rescue by replication. Journal of Virology. 77: 11480-90. PMID 14557633 DOI: 10.1128/Jvi.77.21.11480-11490.2003 |
0.509 |
|
| 2003 |
James JA, Escalante CR, Yoon-Robarts M, Edwards TA, Linden RM, Aggarwal AK. Crystal structure of the SF3 helicase from adeno-associated virus type 2. Structure (London, England : 1993). 11: 1025-35. PMID 12906833 DOI: 10.1016/S0969-2126(03)00152-7 |
0.429 |
|
| 2003 |
Yoon-Robarts M, Linden RM. Identification of active site residues of the adeno-associated virus type 2 Rep endonuclease. The Journal of Biological Chemistry. 278: 4912-8. PMID 12480938 DOI: 10.1074/Jbc.M209750200 |
0.403 |
|
| 2001 |
Ward P, Falkenberg M, Elias P, Weitzman M, Linden RM. Rep-dependent initiation of adeno-associated virus type 2 DNA replication by a herpes simplex virus type 1 replication complex in a reconstituted system. Journal of Virology. 75: 10250-8. PMID 11581393 DOI: 10.1128/Jvi.75.21.10250-10258.2001 |
0.473 |
|
| 2001 |
Nony P, Tessier J, Chadeuf G, Ward P, Giraud A, Dugast M, Linden RM, Moullier P, Salvetti A. Novel cis-acting replication element in the adeno-associated virus type 2 genome is involved in amplification of integrated rep-cap sequences. Journal of Virology. 75: 9991-4. PMID 11559833 DOI: 10.1128/Jvi.75.20.9991-9994.2001 |
0.456 |
|
| 2001 |
Yoon M, Smith DH, Ward P, Medrano FJ, Aggarwal AK, Linden RM. Amino-terminal domain exchange redirects origin-specific interactions of adeno-associated virus rep78 in vitro. Journal of Virology. 75: 3230-9. PMID 11238849 DOI: 10.1128/Jvi.75.7.3230-3239.2001 |
0.502 |
|
| 2000 |
Linden RM, Berns KI. Molecular biology of adeno-associated viruses. Contributions to Microbiology. 4: 68-84. PMID 10941571 DOI: 10.1159/000060327 |
0.555 |
|
| 2000 |
Dutheil N, Shi F, Dupressoir T, Linden RM. Adeno-associated virus site-specifically integrates into a muscle-specific DNA region. Proceedings of the National Academy of Sciences of the United States of America. 97: 4862-6. PMID 10758163 DOI: 10.1073/Pnas.080079397 |
0.479 |
|
| 2000 |
Ward P, Linden RM. A role for single-stranded templates in cell-free adeno-associated virus DNA replication. Journal of Virology. 74: 744-54. PMID 10623736 DOI: 10.1128/Jvi.74.2.744-754.2000 |
0.385 |
|
| 1999 |
Smith DH, Ward P, Linden RM. Comparative characterization of rep proteins from the helper-dependent adeno-associated virus type 2 and the autonomous goose parvovirus. Journal of Virology. 73: 2930-7. PMID 10074142 DOI: 10.1128/Jvi.73.4.2930-2937.1999 |
0.493 |
|
| 1997 |
Linden RM, Berns KI. Site-specific integration by adeno-associated virus: a basis for a potential gene therapy vector. Gene Therapy. 4: 4-5. PMID 9068788 DOI: 10.1038/Sj.Gt.3300357 |
0.631 |
|
| 1996 |
Linden RM, Ward P, Giraud C, Winocour E, Berns KI. Site-specific integration by adeno-associated virus. Proceedings of the National Academy of Sciences of the United States of America. 93: 11288-94. PMID 8876128 DOI: 10.1073/pnas.93.21.11288 |
0.68 |
|
| 1996 |
Linden RM, Winocour E, Berns KI. The recombination signals for adeno-associated virus site-specific integration. Proceedings of the National Academy of Sciences of the United States of America. 93: 7966-72. PMID 8755586 DOI: 10.1073/Pnas.93.15.7966 |
0.648 |
|
| 1995 |
Berns KI, Linden RM. The cryptic life style of adeno-associated virus. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 17: 237-45. PMID 7748178 DOI: 10.1002/Bies.950170310 |
0.649 |
|
| 1992 |
Kotin RM, Linden RM, Berns KI. Characterization of a preferred site on human chromosome 19q for integration of adeno-associated virus DNA by non-homologous recombination. The Embo Journal. 11: 5071-8. PMID 1334463 DOI: 10.1002/J.1460-2075.1992.Tb05614.X |
0.705 |
|
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