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George Perry, AA, BA, PhD, HonD - Publications

Affiliations: 
Biology University of Texas at San Antonio, San Antonio, TX, United States 
Area:
Alzheimer's disease, oxidative stress, cytoskeleton
Website:
http://bio.utsa.edu/faculty/perry.html

500 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Kelley AR, Colley ME, Dyer S, Bach SBH, Zhu X, Perry G. Ethanol-fixed, paraffin-embedded tissue imaging: implications for Alzheimer's disease research. Journal of the American Society For Mass Spectrometry. PMID 32803969 DOI: 10.1021/jasms.0c00195  1
2020 Plascencia-Villa G, Perry G. Status and future directions of clinical trials in Alzheimer's disease. International Review of Neurobiology. 154: 3-50. PMID 32739008 DOI: 10.1016/bs.irn.2020.03.022  1
2020 Reyes-Pablo AE, Campa-Córdoba BB, Luna-Viramontes NI, Ontiveros-Torres MÁ, Villanueva-Fierro I, Bravo-Muñoz M, Sáenz-Ibarra B, Barbosa O, Guadarrama-Ortíz P, Garcés-Ramírez L, de la Cruz F, Harrington CR, Martínez-Robles S, González-Ballesteros E, Perry G, et al. National Dementia BioBank: A Strategy for the Diagnosis and Study of Neurodegenerative Diseases in México. Journal of Alzheimer's Disease : Jad. PMID 32568191 DOI: 10.3233/JAD-191015  1
2020 Veurink G, Perry G, Singh SK. Role of antioxidants and a nutrient rich diet in Alzheimer's disease. Open Biology. 10: 200084. PMID 32543351 DOI: 10.1098/rsob.200084  1
2020 Hernandes-Alejandro M, Montaño S, Harrington CR, Wischik CM, Salas-Casas A, Cortes-Reynosa P, Pérez Salazar E, Cazares-Apatiga J, Apatiga-Perez R, Ontiveros Torres MÁ, Perry G, Pacheco-Herrero M, Luna-Muñoz J. Analysis of the Relationship Between Metalloprotease-9 and Tau Protein in Alzheimer's Disease. Journal of Alzheimer's Disease : Jad. PMID 32538846 DOI: 10.3233/JAD-200146  1
2020 Plascencia-Villa G, Perry G. Preventive and therapeutic strategies in Alzheimer's disease: focus on oxidative stress, redox metals and ferroptosis. Antioxidants & Redox Signaling. PMID 32486897 DOI: 10.1089/ars.2020.8134  1
2020 Wang W, Zhao F, Ma X, Perry G, Zhu X. Mitochondria dysfunction in the pathogenesis of Alzheimer's disease: recent advances. Molecular Neurodegeneration. 15: 30. PMID 32471464 DOI: 10.1186/s13024-020-00376-6  1
2020 Reddy VP, Aryal P, Robinson S, Rafiu R, Obrenovich M, Perry G. Polyphenols in Alzheimer's Disease and in the Gut-Brain Axis. Microorganisms. 8. PMID 32023969 DOI: 10.3390/microorganisms8020199  0.8
2019 Gao J, Wang L, Gao C, Arakawa H, Perry G, Wang X. TDP-43 inhibitory peptide alleviates neurodegeneration and memory loss in an APP transgenic mouse model for Alzheimer's disease. Biochimica Et Biophysica Acta. Molecular Basis of Disease. 165580. PMID 31678156 DOI: 10.1016/j.bbadis.2019.165580  1
2019 Iverson GL, Gardner AJ, Shultz SR, Solomon GS, McCrory P, Zafonte R, Perry G, Hazrati LN, Keene CD, Castellani RJ. Chronic traumatic encephalopathy neuropathology might not be inexorably progressive or unique to repetitive neurotrauma. Brain : a Journal of Neurology. PMID 31670780 DOI: 10.1093/brain/awz286  1
2019 Castellani RJ, Smith M, Bailey K, Perry G, deJong JL. Neuropathology in Consecutive Forensic Consultation Cases with a History of Remote Traumatic Brain Injury. Journal of Alzheimer's Disease : Jad. PMID 31609691 DOI: 10.3233/JAD-190782  1
2019 Singh SK, Srivastav S, Castellani RJ, Plascencia-Villa G, Perry G. Neuroprotective and Antioxidant Effect of Ginkgo biloba Extract Against AD and Other Neurological Disorders. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. PMID 31376068 DOI: 10.1007/s13311-019-00767-8  1
2019 Liu M, Wang L, Gao J, Dong Q, Perry G, Ma X, Wang X. Inhibition of Calpain Protects Against Tauopathy in Transgenic P301S Tau Mice. Journal of Alzheimer's Disease : Jad. PMID 31156179 DOI: 10.3233/JAD-190281  1
2019 Hampel H, Lista S, Mango D, Nisticò R, Perry G, Avila J, Hernandez F, Geerts H, Vergallo A. Lithium as a Treatment for Alzheimer's Disease: The Systems Pharmacology Perspective. Journal of Alzheimer's Disease : Jad. PMID 31156173 DOI: 10.3233/JAD-190197  1
2019 Jones L, Kumar J, Mistry A, Sankar Chittoor Mana T, Perry G, Reddy VP, Obrenovich M. The Transformative Possibilities of the Microbiota and Mycobiota for Health, Disease, Aging, and Technological Innovation. Biomedicines. 7. PMID 30925795 DOI: 10.3390/biomedicines7020024  0.8
2019 Castellani RJ, Plascencia-Villa G, Perry G. The amyloid cascade and Alzheimer's disease therapeutics: theory versus observation. Laboratory Investigation; a Journal of Technical Methods and Pathology. PMID 30760863 DOI: 10.1038/s41374-019-0231-z  1
2019 Tripathy A, Shade A, Erskine B, Bailey K, Grande A, deJong JJ, Perry G, Castellani RJ. No Evidence of Increased Chronic Traumatic Encephalopathy Pathology or Neurodegenerative Proteinopathy in Former Military Service Members: A Preliminary Study. Journal of Alzheimer's Disease : Jad. PMID 30741674 DOI: 10.3233/JAD-181039  1
2019 Rodriguez RA, Liang H, Chen LY, Plascencia-Villa G, Perry G. Single-channel permeability and glycerol affinity of human aquaglyceroporin AQP3. Biochimica Et Biophysica Acta. Biomembranes. PMID 30659792 DOI: 10.1016/j.bbamem.2019.01.008  1
2018 Castellani RJ, Perry G. Tau Biology, Tauopathy, Traumatic Brain Injury, and Diagnostic Challenges. Journal of Alzheimer's Disease : Jad. PMID 30584140 DOI: 10.3233/JAD-180721  1
2018 Wang C, Zhao F, Shen K, Wang W, Siedlak SL, Lee HG, Phelix CF, Perry G, Shen L, Tang B, Yan R, Zhu X. The sterol regulatory element-binding protein 2 is likely dysregulated by tau alterations in Alzheimer disease. Brain Pathology (Zurich, Switzerland). PMID 30515907 DOI: 10.1111/bpa.12691  1
2018 Kelley AR, Bach SBH, Perry G. Analysis of post-translational modifications in Alzheimer's disease by mass spectrometry. Biochimica Et Biophysica Acta. Molecular Basis of Disease. PMID 30481587 DOI: 10.1016/j.bbadis.2018.11.002  1
2018 Pinho TS, Correia SC, Perry G, Ambrósio AF, Moreira PI. Diminished O-GlcNAcylation in Alzheimer's disease is strongly correlated with mitochondrial anomalies. Biochimica Et Biophysica Acta. Molecular Basis of Disease. PMID 30412792 DOI: 10.1016/j.bbadis.2018.10.037  1
2018 Frank L, Wesson Ashford J, Bayley P, Borson S, Buschke H, Cohen D, Cummings JL, Davies P, Dean M, Finkel SI, Hyer L, Perry G, Powers RE, Schmitt F. Genetic Risk of Alzheimer's Disease: Three Wishes Now That the Genie is Out of the Bottle. Journal of Alzheimer's Disease : Jad. PMID 30282369 DOI: 10.3233/JAD-180629  0.8
2018 Wang L, Gao J, Liu J, Siedlak SL, Torres S, Fujioka H, Huntley ML, Jiang Y, Ji H, Yan T, Harland M, Termsarasab P, Zeng S, Jiang Z, Liang J, ... Perry G, et al. Mitofusin 2 Regulates Axonal Transport of Calpastatin to Prevent Neuromuscular Synaptic Elimination in Skeletal Muscles. Cell Metabolism. PMID 30017354 DOI: 10.1016/j.cmet.2018.06.011  1
2018 Liang H, Bourdon A, Chen LY, Phelix CF, Perry G. Gibbs free-energy gradient along the path of glucose transport through human glucose transporter 3. Acs Chemical Neuroscience. PMID 29865792 DOI: 10.1021/acschemneuro.8b00223  1
2018 Mahmoudi M, Pakpour S, Perry G. Drug-Abuse Nanotechnology: Opportunities and Challenges. Acs Chemical Neuroscience. PMID 29851334 DOI: 10.1021/acschemneuro.8b00127  1
2018 Smith MA, Bowen RL, Nguyen RQ, Perry G, Atwood CS, Rimm AA. Putative Gonadotropin Releasing Hormone Agonist Therapy and Dementia: An Application of Medicare Hospitalization Claims Data. Journal of Alzheimer's Disease : Jad. PMID 29782310 DOI: 10.3233/JAD-170847  1
2018 Mondragón Rodríguez S, Salas Gallardo A, Gonzalez Pereyra P, Macías M, Ordaz B, Peña Ortega F, Aguilar Vazquez A, Orta Salazar E, Díaz Cintra S, Perry G, Williams S. Phosphorylation of tau protein correlates with changes in hippocampal theta oscillations and reduces hippocampal excitability in Alzheimer's model. The Journal of Biological Chemistry. PMID 29632073 DOI: 10.1074/jbc.RA117.001187  1
2018 Paley EL, Perry G. Towards an Integrative Understanding of tRNA Aminoacylation-Diet-Host-Gut Microbiome Interactions in Neurodegeneration. Nutrients. 10. PMID 29587458 DOI: 10.3390/nu10040410  1
2018 Perry G, Avila J, Zhu X. Birth of JAD: 20 Years Later. Journal of Alzheimer's Disease : Jad. 62: 901. PMID 29562547 DOI: 10.3233/JAD-180120  1
2018 Yan T, Wang L, Gao J, Siedlak SL, Huntley ML, Termsarasab P, Perry G, Chen SG, Wang X. Rab10 Phosphorylation is a Prominent Pathological Feature in Alzheimer's Disease. Journal of Alzheimer's Disease : Jad. PMID 29562525 DOI: 10.3233/JAD-180023  1
2018 Gao J, Wang L, Huntley ML, Perry G, Wang X. Pathomechanisms of TDP-43 in neurodegeneration. Journal of Neurochemistry. PMID 29486049 DOI: 10.1111/jnc.14327  1
2018 Jiang S, Nandy P, Wang W, Ma X, Hsia J, Wang C, Wang Z, Niu M, Siedlak SL, Torres S, Fujioka H, Xu Y, Lee HG, Perry G, Liu J, et al. Mfn2 ablation causes an oxidative stress response and eventual neuronal death in the hippocampus and cortex. Molecular Neurodegeneration. 13: 5. PMID 29391029 DOI: 10.1186/s13024-018-0238-8  1
2018 Plascencia-Villa G, Perry G. Iron·ic facts about dementia. Journal of Neurology, Neurosurgery, and Psychiatry. PMID 29353235 DOI: 10.1136/jnnp-2017-317164  1
2018 Kelley AR, Perry G, Bach SBH. Characterization of Proteins Present in Isolated Senile Plaques from Alzheimer's Diseased Brains by MALDI-TOF MS with MS/MS. Acs Chemical Neuroscience. PMID 29301075 DOI: 10.1021/acschemneuro.7b00445  1
2017 Henderson LE, Abdelmegeed MA, Yoo SH, Rhee SG, Zhu X, Smith MA, Nguyen RQ, Perry G, Song BJ. Enhanced Phosphorylation of Bax and Its Translocation into Mitochondria in the Brains of Individuals Affiliated with Alzheimer's Disease. The Open Neurology Journal. 11: 48-58. PMID 29290835 DOI: 10.2174/1874205X01711010048  1
2017 Rodriguez RA, Chen LY, Plascencia-Villa G, Perry G. Thermodynamics of amyloid-β fibril elongation: atomistic details of the transition state. Acs Chemical Neuroscience. PMID 29239603 DOI: 10.1021/acschemneuro.7b00409  1
2017 Martín-Maestro P, Gargini R, García E, Perry G, Avila J, García-Escudero V. Slower Dynamics and Aged Mitochondria in Sporadic Alzheimer's Disease. Oxidative Medicine and Cellular Longevity. 2017: 9302761. PMID 29201274 DOI: 10.1155/2017/9302761  1
2017 Kelley AR, Colley ME, Perry G, Bach SBH. Incubation with Cu(II) and Zn(II) salts enhances MALDI-TOF mass spectra of amyloid-beta and α-synuclein toward in-vivo analysis. Journal of Mass Spectrometry : Jms. PMID 29111606 DOI: 10.1002/jms.4044  1
2017 Iverson GL, Keene CD, Perry G, Castellani RJ. The Need to Separate Chronic Traumatic Encephalopathy Neuropathology from Clinical Features. Journal of Alzheimer's Disease : Jad. PMID 29103039 DOI: 10.3233/JAD-170654  1
2017 Castellani RJ, Perry G. Dementia Pugilistica Revisited. Journal of Alzheimer's Disease : Jad. 60: 1209-1221. PMID 29036831 DOI: 10.3233/JAD-170669  1
2017 Wambo TO, Chen LY, Phelix C, Perry G. Affinity and path of binding xylopyranose unto E. coli xylose permease. Biochemical and Biophysical Research Communications. PMID 29032199 DOI: 10.1016/j.bbrc.2017.10.053  1
2017 Wang W, Yin J, Ma X, Zhao F, Siedlak SL, Wang Z, Fujioka H, Xu Y, Perry G, Zhu X. Inhibition of mitochondrial fragmentation protects against Alzheimer's disease in rodent model. Human Molecular Genetics. PMID 28973308 DOI: 10.1093/hmg/ddx299  1
2017 Nunomura A, Lee HG, Zhu X, Perry G. Consequences of RNA oxidation on protein synthesis rate and fidelity: implications for the pathophysiology of neuropsychiatric disorders. Biochemical Society Transactions. PMID 28778984 DOI: 10.1042/BST20160433  1
2017 Putta S, Yarla NS, Peluso I, Tiwari DK, Reddy GV, Giri PV, Kumar N, Malla R, Chari VB, Reddy D RS, Bade R, Mannarapu M, Barretto G, Lu DY, Tarasov VV, ... ... Perry G, et al. Anthocyanins: Possible role as Multitarget therapeutic agents for prevention and therapy of chronic diseases. Current Pharmaceutical Design. PMID 28741457 DOI: 10.2174/1381612823666170519151801  1
2017 Siedlak SL, Jiang Y, Huntley ML, Wang L, Gao J, Xie F, Liu J, Su B, Perry G, Wang X. TMEM230 Accumulation in Granulovacuolar Degeneration Bodies and Dystrophic Neurites of Alzheimer's Disease. Journal of Alzheimer's Disease : Jad. PMID 28527219 DOI: 10.3233/JAD-170190  1
2017 Rodriguez RA, Chen LY, Plascencia-Villa G, Perry G. Elongation affinity, activation barrier, and stability of Aβ42 oligomers/fibrils in physiological saline. Biochemical and Biophysical Research Communications. PMID 28427941 DOI: 10.1016/j.bbrc.2017.04.084  1
2016 Forero DA, Prada CF, Perry G. Functional and Genomic Features of Human Genes Mutated in Neuropsychiatric Disorders. The Open Neurology Journal. 10: 143-148. PMID 27990183 DOI: 10.2174/1874205X01610010143  1
2016 Castellani RJ, Mojica G, Perry G. The Role of the Iron Stain in Assessing Intracranial Hemorrhage. The Open Neurology Journal. 10: 136-142. PMID 27857815 DOI: 10.2174/1874205X01610010136  1
2016 Kelley AR, Perry G, Bethea C, Castellani RJ, Bach SB. Molecular Mapping Alzheimer's Disease: MALDI Imaging of Formalin-fixed, Paraffin-embedded Human Hippocampal Tissue. The Open Neurology Journal. 10: 88-98. PMID 27843502 DOI: 10.2174/1874205X01610010088  1
2016 Nunomura A, Zhu X, Perry G. Modulation of Parkinson's Disease Associated Protein Rescues Alzheimer's Disease Degeneration. Journal of Alzheimer's Disease : Jad. PMID 27802241 DOI: 10.3233/JAD-160878  1
2016 Rueli RH, Torres DJ, Dewing AS, Kiyohara AC, Barayuga SM, Bellinger MT, Uyehara-Lock JH, White LR, Moreira PI, Berry MJ, Perry G, Bellinger FP. Selenoprotein S Reduces Endoplasmic Reticulum Stress-Induced Phosphorylation of Tau: Potential Role in Selenate Mitigation of Tau Pathology. Journal of Alzheimer's Disease : Jad. PMID 27802219 DOI: 10.3233/JAD-151208  1
2016 Mondragón-Rodríguez S, Perry G, Peña-Ortega F, Williams S. Tau, Amyloid beta and Deep brain stimulation: Aiming to restore cognitive deficit in Alzheimer's disease. Current Alzheimer Research. PMID 27539594 DOI: 10.2174/1567205013666160819131336  1
2016 Correia SC, Perry G, Moreira PI. Mitochondrial traffic jams in Alzheimer's disease - pinpointing the roadblocks. Biochimica Et Biophysica Acta. PMID 27460705 DOI: 10.1016/j.bbadis.2016.07.010  1
2016 Manassero G, Guglielmotto M, Zamfir R, Borghi R, Colombo L, Salmona M, Perry G, Odetti P, Arancio O, Tamagno E, Tabaton M. Beta-amyloid 1-42 monomers, but not oligomers, produce PHF-like conformation of Tau protein. Aging Cell. PMID 27406053 DOI: 10.1111/acel.12500  1
2016 Hofer T, Perry G. Nucleic acid oxidative damage in Alzheimer's disease-explained by the hepcidin-ferroportin neuronal iron overload hypothesis? Journal of Trace Elements in Medicine and Biology : Organ of the Society For Minerals and Trace Elements (Gms). PMID 27329321 DOI: 10.1016/j.jtemb.2016.06.005  0.92
2016 Plascencia-Villa G, Ponce A, Collingwood JF, Arellano-Jiménez MJ, Zhu X, Rogers JT, Betancourt I, José-Yacamán M, Perry G. High-resolution analytical imaging and electron holography of magnetite particles in amyloid cores of Alzheimer's disease. Scientific Reports. 6: 24873. PMID 27121137 DOI: 10.1038/srep24873  1
2016 Forero DA, González-Giraldo Y, López-Quintero C, Castro-Vega LJ, Barreto GE, Perry G. Meta-analysis of Telomere Length in Alzheimer's Disease. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. PMID 27091133 DOI: 10.1093/gerona/glw053  1
2016 Singh SK, Srivastav S, Yadav AK, Srikrishna S, Perry G. Overview of Alzheimer's Disease and Some Therapeutic Approaches Targeting Aβ by Using Several Synthetic and Herbal Compounds. Oxidative Medicine and Cellular Longevity. 2016: 7361613. PMID 27034741 DOI: 10.1155/2016/7361613  1
2016 Ontiveros-Torres MÁ, Labra-Barrios ML, Díaz-Cintra S, Aguilar-Vázquez AR, Moreno-Campuzano S, Flores-Rodríguez P, Luna-Herrera C, Mena R, Perry G, Florán-Garduño B, Luna-Muñoz J, Luna-Arias JP. Fibrillar Amyloid-β Accumulation Triggers an Inflammatory Mechanism Leading to Hyperphosphorylation of the Carboxyl-Terminal End of Tau Polypeptide in the Hippocampal Formation of the 3×Tg-AD Transgenic Mouse. Journal of Alzheimer's Disease : Jad. 52: 243-69. PMID 27031470 DOI: 10.3233/JAD-150837  1
2016 Itzhaki RF, Lathe R, Balin BJ, Ball MJ, Bearer EL, Braak H, Bullido MJ, Carter C, Clerici M, Cosby SL, Del Tredici K, Field H, Fulop T, Grassi C, Griffin WS, ... ... Perry G, et al. Microbes and Alzheimer's Disease. Journal of Alzheimer's Disease : Jad. PMID 26967229 DOI: 10.3233/JAD-160152  1
2016 Wang C, Zhang F, Jiang S, Siedlak SL, Shen L, Perry G, Wang X, Tang B, Zhu X. Estrogen receptor-α is localized to neurofibrillary tangles in Alzheimer's disease. Scientific Reports. 6: 20352. PMID 26837465 DOI: 10.1038/srep20352  1
2016 Calderón-Garcidueñas L, Reynoso-Robles R, Vargas-Martínez J, Gómez-Maqueo-Chew A, Pérez-Guillé B, Mukherjee PS, Torres-Jardón R, Perry G, Gónzalez-Maciel A. Prefrontal white matter pathology in air pollution exposed Mexico City young urbanites and their potential impact on neurovascular unit dysfunction and the development of Alzheimer's disease. Environmental Research. 146: 404-417. PMID 26829765 DOI: 10.1016/j.envres.2015.12.031  1
2016 Forero DA, González-Giraldo Y, López-Quintero C, Castro-Vega LJ, Barreto GE, Perry G. Telomere length in Parkinson's disease: A meta-analysis. Experimental Gerontology. 75: 53-5. PMID 26772888 DOI: 10.1016/j.exger.2016.01.002  1
2016 Forero DA, Wonkam A, Wang W, Laissue P, López-Correa C, Fernández-López JC, Mugasimangalam R, Perry G. Current needs for human and medical genomics research infrastructure in low and middle income countries. Journal of Medical Genetics. PMID 26740506 DOI: 10.1136/jmedgenet-2015-103631  1
2016 Martín-Maestro P, Gargini R, Perry G, Avila J, García-Escudero V. PARK2 enhancement is able to compensate mitophagy alterations found in sporadic Alzheimer's disease. Human Molecular Genetics. 25: 792-806. PMID 26721933 DOI: 10.1093/hmg/ddv616  1
2016 Singh SK, Srivastav S, Yadav AK, Srikrishna S, Perry G. Overview of Alzheimer's disease and some therapeutic approaches targeting A β by using several synthetic and herbal compounds Oxidative Medicine and Cellular Longevity. 2016. DOI: 10.1155/2016/7361613  1
2016 Forero DA, González-Giraldo Y, López-Quintero C, Castro-Vega LJ, Barreto GE, Perry G. Telomere length in Parkinson's disease: A meta-analysis Experimental Gerontology. 75: 53-55. DOI: 10.1016/j.exger.2016.01.002  1
2015 Kelley AR, Perry G, Castellani RJ, Bach SB. Laser-Induced In-Source Decay Applied to the Determination of Amyloid-Beta in Alzheimer's Brains. Acs Chemical Neuroscience. PMID 26720297 DOI: 10.1021/acschemneuro.5b00295  1
2015 Sharoar MG, Shi Q, Ge Y, He W, Hu X, Perry G, Zhu X, Yan R. Dysfunctional tubular endoplasmic reticulum constitutes a pathological feature of Alzheimer's disease. Molecular Psychiatry. PMID 26619807 DOI: 10.1038/mp.2015.181  1
2015 Zivkovic L, Bajic V, Perry G, Spremo-Potparevica B. Alterations of the X Chromosome in Lymphocytes of Alzheimer's Disease Patients. Current Alzheimer Research. PMID 26502819  0.16
2015 Yu L, Villarreal OD, Laurie Chen L, Chen LY. 1,3-Propanediol binds inside the water-conducting pore of aquaporin 4: Does this efficacious inhibitor have sufficient potency? Protein Science : a Publication of the Protein Society. PMID 26481430 DOI: 10.1002/pro.2832  1
2015 Jiang Z, Wang W, Perry G, Zhu X, Wang X. Mitochondrial dynamic abnormalities in amyotrophic lateral sclerosis. Translational Neurodegeneration. 4: 14. PMID 26225210 DOI: 10.1186/s40035-015-0037-x  1
2015 Zhang F, Wang W, Siedlak SL, Liu Y, Liu J, Jiang K, Perry G, Zhu X, Wang X. Miro1 deficiency in amyotrophic lateral sclerosis. Frontiers in Aging Neuroscience. 7: 100. PMID 26074815 DOI: 10.3389/fnagi.2015.00100  1
2015 Calderón-Garcidueñas L, Franco-Lira M, D'Angiulli A, Rodríguez-Díaz J, Blaurock-Busch E, Busch Y, Chao CK, Thompson C, Mukherjee PS, Torres-Jardón R, Perry G. Mexico City normal weight children exposed to high concentrations of ambient PM2.5 show high blood leptin and endothelin-1, vitamin D deficiency, and food reward hormone dysregulation versus low pollution controls. Relevance for obesity and Alzheimer disease. Environmental Research. 140: 579-92. PMID 26037109 DOI: 10.1016/j.envres.2015.05.012  1
2015 Zhang F, Su B, Wang C, Siedlak SL, Mondragon-Rodriguez S, Lee HG, Wang X, Perry G, Zhu X. Posttranslational modifications of α-tubulin in alzheimer disease. Translational Neurodegeneration. 4: 9. PMID 26029362 DOI: 10.1186/s40035-015-0030-4  1
2015 Avila J, Perry G, Strange BA, Hernandez F. Alternative neural circuitry that might be impaired in the development of Alzheimer disease. Frontiers in Neuroscience. 9: 145. PMID 25954151 DOI: 10.3389/fnins.2015.00145  1
2015 Castellani RJ, Perry G, Iverson GL. Chronic effects of mild neurotrauma: putting the cart before the horse? Journal of Neuropathology and Experimental Neurology. 74: 493-9. PMID 25933385 DOI: 10.1097/NEN.0000000000000193  1
2015 Pelcovits A, Marriotti R, Heath J, Perry G, Castellani RJ. Simultaneous onset of Alzheimer's disease in a husband and wife in their mid-fifties: what do we really know about environmental factors? The Open Neurology Journal. 9: 1-3. PMID 25932054 DOI: 10.2174/1874205X01509010001  1
2015 Gerenu G, Liu K, Chojnacki JE, Saathoff JM, Martínez-Martín P, Perry G, Zhu X, Lee HG, Zhang S. Curcumin/Melatonin Hybrid 5-(4-Hydroxy-phenyl)-3-oxo-pentanoic Acid [2-(5-Methoxy-1H-indol-3-yl)-ethyl]-amide Ameliorates AD-Like Pathology in the APP/PS1 Mouse Model. Acs Chemical Neuroscience. PMID 25893520 DOI: 10.1021/acschemneuro.5b00082  1
2015 Rodriguez AR, Plascencia-Villa G, Witt CM, Yu JJ, José-Yacamán M, Chambers JP, Perry G, Guentzel MN, Arulanandam BP. Chlamydia pneumoniae promotes dysfunction of pancreatic beta cells. Cellular Immunology. 295: 83-91. PMID 25863744 DOI: 10.1016/j.cellimm.2015.03.010  1
2015 Luna-Muñoz J, Perry G, Guevara J. Raúl Mena: 1953-2014. Journal of Alzheimer's Disease : Jad. 45: 325-7. PMID 25757649 DOI: 10.3233/JAD-150134  1
2015 Petersen RB, Lissemore FM, Appleby B, Aggarwal N, Boyatzis R, Casadesus G, Cummings J, Jack A, Perry G, Safar J, Sajatovic M, Surewicz W, Wang Y, Whitehouse P, Lerner A. From Neurodegeneration to Brain Health: An Integrated Approach. Journal of Alzheimer's Disease : Jad. PMID 25720413 DOI: 10.3233/JAD-150043  1
2015 Perry G. Two hundred treasured issues! Journal of Alzheimer's Disease : Jad. 44: 725. PMID 25663057 DOI: 10.3233/JAD-142264  0.01
2015 Carvalho C, Correia SC, Perry G, Castellani RJ, Moreira PI. Cerebrovascular and mitochondrial abnormalities in Alzheimer's disease: a brief overview. Journal of Neural Transmission (Vienna, Austria : 1996). PMID 25608860 DOI: 10.1007/s00702-015-1367-7  1
2015 Bowen RL, Perry G, Xiong C, Smith MA, Atwood CS. A clinical study of lupron depot in the treatment of women with Alzheimer's disease: preservation of cognitive function in patients taking an acetylcholinesterase inhibitor and treated with high dose lupron over 48 weeks. Journal of Alzheimer's Disease : Jad. 44: 549-60. PMID 25310993 DOI: 10.3233/JAD-141626  1
2015 Hammack CD, Perry G, LeBaron RG, Villareal G, Phelix CF. Low Dose Pioglitazone Attenuates Oxidative Damage in Early Alzheimer's Disease by Binding mitoNEET International Journal of Knowledge Discovery in Bioinformatics. 5: 24-45. DOI: 10.4018/IJKDB.2015010103  1
2015 Avila J, Perry G, Strange BA, Hernandez F. Alternative neural circuitry that might be impaired in the development of Alzheimer disease Frontiers in Neuroscience. 9. DOI: 10.3389/fnins.2015.00145  1
2015 Perry G. Two hundred treasured issues! Journal of Alzheimer's Disease. 44: 725. DOI: 10.3233/JAD-142264  1
2015 Correia SC, Moreira PI, Perry G. Autophagy in alzheimer’s disease: A cleaning service out-of-order? Toxicity and Autophagy in Neurodegenerative Disorders. 123-142. DOI: 10.1007/978-3-319-13939-5_7  1
2015 Perry G. Meet our editorial board member Mini-Reviews in Medicinal Chemistry. 15: 719.  1
2015 Pelcovits A, Marriotti R, Heath J, Perry G, Castellani RJ. Simultaneous Onset of Alzheimer’s Disease in a Husband and Wife in their Mid-Fifties: What do we Really know about Environmental Factors? Open Neurology Journal. 9: 1-3.  1
2015 Rahman AU, Choudhary MI, Perry G. Overview Mini-Reviews in Medicinal Chemistry. 15: 2-3.  1
2015 Perry G. Meet the editorial board Current Protein and Peptide Science. 16: 181.  1
2015 Atta-ur-Rahman, Iqbal Choudhary M, Perry G. Recent Advances in Medicinal Chemistry Recent Advances in Medicinal Chemistry. 1: 1-469.  1
2015 Perry G. Preface Recent Advances in Medicinal Chemistry. 1: ix.  1
2014 Habibi L, Perry G, Mahmoudi M. Global warming and neurodegenerative disorders: speculations on their linkage. Bioimpacts : Bi. 4: 167-70. PMID 25671171 DOI: 10.15171/bi.2014.013  1
2014 Fornicola W, Pelcovits A, Li BX, Heath J, Perry G, Castellani RJ. Alzheimer Disease Pathology in Middle Age Reveals a Spatial-Temporal Disconnect Between Amyloid-β and Phosphorylated Tau. The Open Neurology Journal. 8: 22-6. PMID 25628768 DOI: 10.2174/1874205X01408010022  1
2014 Forero DA, Vélez-van-Meerbeke A, Deshpande SN, Nicolini H, Perry G. Neuropsychiatric genetics in developing countries: Current challenges. World Journal of Psychiatry. 4: 69-71. PMID 25540721 DOI: 10.5498/wjp.v4.i4.69  1
2014 Fawver JN, Ghiwot Y, Koola C, Carrera W, Rodriguez-Rivera J, Hernandez C, Dineley KT, Kong Y, Li J, Jhamandas J, Perry G, Murray IV. Islet amyloid polypeptide (IAPP): a second amyloid in Alzheimer's disease. Current Alzheimer Research. 11: 928-40. PMID 25387341  1
2014 Xia J, Rocke DM, Perry G, Ray M. Differential network analyses of Alzheimer's disease identify early events in Alzheimer's disease pathology. International Journal of Alzheimer's Disease. 2014: 721453. PMID 25147748 DOI: 10.1155/2014/721453  0.16
2014 Rodrigues R, Petersen RB, Perry G. Parallels between major depressive disorder and Alzheimer's disease: role of oxidative stress and genetic vulnerability. Cellular and Molecular Neurobiology. 34: 925-49. PMID 24927694 DOI: 10.1007/s10571-014-0074-5  1
2014 Brinkley WR, Perry G. Lester (Skip) Binder (1949-2013): in the beginning was tau. Journal of Alzheimer's Disease : Jad. 40: S5. PMID 24867914 DOI: 10.3233/JAD-140877  1
2014 Bonda DJ, Wang X, Lee HG, Smith MA, Perry G, Zhu X. Neuronal failure in Alzheimer's disease: a view through the oxidative stress looking-glass. Neuroscience Bulletin. 30: 243-52. PMID 24733654 DOI: 10.1007/s12264-013-1424-x  1
2014 Blair JA, Siedlak SL, Wolfram JA, Nunomura A, Castellani RJ, Ferreira ST, Klein WL, Wang Y, Casadesus G, Smith MA, Perry G, Zhu X, Lee HG. Accumulation of intraneuronal amyloid-β is common in normal brain. Current Alzheimer Research. 11: 317-24. PMID 24597504 DOI: 10.2174/1567205011666140302200902  1
2014 Rosen AC, Ashford JW, Perry G. Ethics review as a catalyst for progress. Journal of Alzheimer's Disease : Jad. 40: 233-5. PMID 24583402 DOI: 10.3233/JAD-132762  1
2014 Perry G, Castellani R. Plaques and tangles: Birthmarks of the aging soul Biochemical Pharmacology. 88: 423-425. PMID 24486570 DOI: 10.1016/j.bcp.2014.01.028  1
2014 Castellani RJ, Perry G. The complexities of the pathology-pathogenesis relationship in Alzheimer disease. Biochemical Pharmacology. 88: 671-6. PMID 24447936 DOI: 10.1016/j.bcp.2014.01.009  1
2014 Johnston JM, Hu WT, Fardo DW, Greco SJ, Perry G, Montine TJ, Trojanowski JQ, Shaw LM, Ashford JW, Tezapsidis N. Low plasma leptin in cognitively impaired ADNI subjects: gender differences and diagnostic and therapeutic potential. Current Alzheimer Research. 11: 165-74. PMID 24359504 DOI: 10.2174/1567205010666131212114156  1
2014 Wang X, Wang W, Li L, Perry G, Lee HG, Zhu X. Oxidative stress and mitochondrial dysfunction in Alzheimer's disease. Biochimica Et Biophysica Acta. 1842: 1240-7. PMID 24189435 DOI: 10.1016/j.bbadis.2013.10.015  1
2014 Mondragón-Rodríguez S, Perry G, Luna-Muñoz J, Acevedo-Aquino MC, Williams S. Phosphorylation of tau protein at sites Ser(396-404) is one of the earliest events in Alzheimer's disease and Down syndrome. Neuropathology and Applied Neurobiology. 40: 121-35. PMID 24033439 DOI: 10.1111/nan.12084  1
2014 Bonda DJ, Stone JG, Torres SL, Siedlak SL, Perry G, Kryscio R, Jicha G, Casadesus G, Smith MA, Zhu X, Lee HG. Dysregulation of leptin signaling in Alzheimer disease: evidence for neuronal leptin resistance. Journal of Neurochemistry. 128: 162-72. PMID 23895348 DOI: 10.1111/jnc.12380  1
2014 Perry G. Looking at Alzheimer's disease from a different angle Future Neurology. 9: 19-22. DOI: 10.2217/fnl.13.68  1
2014 Blair JA, Siedlak SL, Wolfram JA, Nunomura A, Castellani RJ, Ferreira ST, Klein WL, Wang Y, Casadesus G, Smith MA, Perry G, Zhu X, Lee Hg. Accumulation of intraneuronal amyloid-β is common in normal brain Current Alzheimer Research. 11: 317-324. DOI: 10.2174/1567205011666140302200902  1
2014 Habibi L, Perry G, Mahmoudi M. Global warming and neurodegenerative disorders: Speculations on their linkage Bioimpacts. 4: 167-170. DOI: 10.15171/bi.2014.013  1
2014 Phelix CF, Villareal G, Lebaron RG, Perry G, Roberson DJ. Precision medicine using individualized biosimulations of drug dosing: Alzheimer's disease 2014 Ieee Healthcare Innovation Conference, Hic 2014. 292-295. DOI: 10.1109/HIC.2014.7038932  1
2014 Castellani RJ, Zhu X, Perry G, Moreira PI. Alzheimer's Disease: An Overview Reference Module in Biomedical Research. DOI: 10.1016/B978-0-12-801238-3.04491-3  1
2014 Castellani RJ, Moreira PI, Zhu X, Perry G. Alzheimer's Disease: Pathology and Pathogenesis Reference Module in Biomedical Research. DOI: 10.1016/B978-0-12-801238-3.00160-4  1
2014 Fawver JN, Ghiwot Y, Koola C, Carrera W, Rodriguez-Rivera J, Hernandez C, Dineley KT, Kong Y, Li J, Jhamandas J, Perry G, Murray IVJ. Islet amyloid polypeptide (iapp): A second amyloid in alzheimer’s disease Current Alzheimer Research. 11: 928-940.  1
2014 Fornicola W, Pelcovits A, Li BX, Heath J, Perry G, Castellani RJ. Alzheimer Disease Pathology in Middle Age Reveals a Spatial-Temporal Disconnect Between Amyloid-β and Phosphorylated Tau Open Neurology Journal. 8: 22-26.  1
2014 Johnston JM, Perry G, Ashford JW, Tezapsidis N. Leptin in alzheimer's disease and other cognitive disorders and its association with underlying lipid abnormalities Leptin: Biosynthesis, Functions and Clinical Significance. 1-15.  1
2013 Bharadwaj PR, Bates KA, Porter T, Teimouri E, Perry G, Steele JW, Gandy S, Groth D, Martins RN, Verdile G. Latrepirdine: molecular mechanisms underlying potential therapeutic roles in Alzheimer's and other neurodegenerative diseases. Translational Psychiatry. 3: e332. PMID 24301650 DOI: 10.1038/tp.2013.97  1
2013 Fujioka H, Phelix CF, Friedland RP, Zhu X, Perry EA, Castellani RJ, Perry G. Apolipoprotein E4 prevents growth of malaria at the intraerythrocyte stage: implications for differences in racial susceptibility to Alzheimer's disease. Journal of Health Care For the Poor and Underserved. 24: 70-8. PMID 24241262 DOI: 10.1353/hpu.2014.0009  1
2013 Jarero-Basulto JJ, Luna-Muñoz J, Mena R, Kristofikova Z, Ripova D, Perry G, Binder LI, Garcia-Sierra F. Proteolytic cleavage of polymeric tau protein by caspase-3: implications for Alzheimer disease. Journal of Neuropathology and Experimental Neurology. 72: 1145-61. PMID 24226268 DOI: 10.1097/NEN.0000000000000013  0.44
2013 Williams WM, Torres S, Siedlak SL, Castellani RJ, Perry G, Smith MA, Zhu X. Antimicrobial peptide β-defensin-1 expression is upregulated in Alzheimer's brain. Journal of Neuroinflammation. 10: 127. PMID 24139179 DOI: 10.1186/1742-2094-10-127  1
2013 Paley EL, Perry G, Sokolova O. Tryptamine induces axonopathy and mitochondriopathy mimicking neurodegenerative diseases via tryptophanyl-tRNA deficiency. Current Alzheimer Research. 10: 987-1004. PMID 24117115 DOI: 10.2174/15672050113106660164  1
2013 Correia SC, Perry G, Castellani R, Moreira PI. Is exercise-in-a-bottle likely to proffer new insights into Alzheimer's disease? Journal of Neurochemistry. 127: 4-6. PMID 24074055 DOI: 10.1111/jnc.12406  1
2013 Mondragón-Rodríguez S, Perry G, Zhu X, Moreira PI, Acevedo-Aquino MC, Williams S. Phosphorylation of tau protein as the link between oxidative stress, mitochondrial dysfunction, and connectivity failure: implications for Alzheimer's disease. Oxidative Medicine and Cellular Longevity. 2013: 940603. PMID 23936615 DOI: 10.1155/2013/940603  1
2013 Schrag M, Mueller C, Zabel M, Crofton A, Kirsch WM, Ghribi O, Squitti R, Perry G. Oxidative stress in blood in Alzheimer's disease and mild cognitive impairment: a meta-analysis. Neurobiology of Disease. 59: 100-10. PMID 23867235 DOI: 10.1016/j.nbd.2013.07.005  1
2013 García-Escudero V, Martín-Maestro P, Perry G, Avila J. Deconstructing mitochondrial dysfunction in Alzheimer disease. Oxidative Medicine and Cellular Longevity. 2013: 162152. PMID 23840916 DOI: 10.1155/2013/162152  1
2013 Hou L, Lee HG, Han F, Tedesco JM, Perry G, Smith MA, Zagorski MG. Modification of amyloid-β1-42 fibril structure by methionine-35 oxidation. Journal of Alzheimer's Disease : Jad. 37: 9-18. PMID 23719512 DOI: 10.3233/JAD-122389  1
2013 Perry EA, Castellani RJ, Moreira PI, Nunomura A, Lui Q, Harris PL, Sayre LM, Szweda PA, Szweda LI, Zhu X, Smith MA, Perry G. Neurofilaments are the major neuronal target of hydroxynonenal-mediated protein cross-links. Free Radical Research. 47: 507-10. PMID 23566300 DOI: 10.3109/10715762.2013.794265  1
2013 Durán-González J, Michi ED, Elorza B, Perez-Córdova MG, Pacheco-Otalora LF, Touhami A, Paulson P, Perry G, Murray IV, Colom LV. Amyloid β peptides modify the expression of antioxidant repair enzymes and a potassium channel in the septohippocampal system. Neurobiology of Aging. 34: 2071-6. PMID 23473707 DOI: 10.1016/j.neurobiolaging.2013.02.005  1
2013 Perry G. The Largest Unmet Market: Chronic Diseases of Aging Mini-Reviews in Medicinal Chemistry. 13: 1. PMID 23447815  1
2013 Coskuner O, Wise-Scira O, Perry G, Kitahara T. The structures of the E22Δ mutant-type amyloid-β alloforms and the impact of E22Δ mutation on the structures of the wild-type amyloid-β alloforms. Acs Chemical Neuroscience. 4: 310-20. PMID 23421682 DOI: 10.1021/cn300149j  1
2013 Zivković L, Spremo-Potparević B, Siedlak SL, Perry G, PlećaÅ¡-Solarović B, Milićević Z, Bajić VP. DNA damage in Alzheimer disease lymphocytes and its relation to premature centromere division. Neuro-Degenerative Diseases. 12: 156-63. PMID 23406622 DOI: 10.1159/000346114  1
2013 Perry G, Zhu X, Smith MA, Sorensen A, Avila J. Preface. Alzheimer's disease: advances for a new century. Journal of Alzheimer's Disease : Jad. 33: S1. PMID 23397602  1
2013 Haldar S, Beveridge 'J, Wong J, Singh A, Galimberti D, Borroni B, Zhu X, Blevins J, Greenlee J, Perry G, Mukhopadhyay CK, Schmotzer C, Singh N. A low-molecular-weight ferroxidase is increased in the CSF of sCJD cases: CSF ferroxidase and transferrin as diagnostic biomarkers for sCJD. Antioxidants & Redox Signaling. 19: 1662-75. PMID 23379482 DOI: 10.1089/ars.2012.5032  1
2013 Colom LV, Perry G, Kuljis RO. Tackling the elusive challenges relevant to conquering the 100-plus year old problem of Alzheimer's disease. Current Alzheimer Research. 10: 108-16. PMID 23368433  1
2013 Santos RX, Correia SC, Zhu X, Smith MA, Moreira PI, Castellani RJ, Nunomura A, Perry G. Mitochondrial DNA oxidative damage and repair in aging and Alzheimer's disease. Antioxidants & Redox Signaling. 18: 2444-57. PMID 23216311 DOI: 10.1089/ars.2012.5039  1
2013 Correia SC, Santos RX, Santos MS, Casadesus G, Lamanna JC, Perry G, Smith MA, Moreira PI. Mitochondrial abnormalities in a streptozotocin-induced rat model of sporadic Alzheimer's disease. Current Alzheimer Research. 10: 406-19. PMID 23061885 DOI: 10.2174/1567205011310040006  1
2013 Zhu X, Perry G, Smith MA, Wang X. Abnormal mitochondrial dynamics in the pathogenesis of Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 33: S253-62. PMID 22531428 DOI: 10.3233/JAD-2012-129005  1
2013 Perry G, Zhu X, Smith MA, Sorensen A, Avila J. Alzheimer's disease: Advances for a new century Journal of Alzheimer's Disease. 33: S1. DOI: 10.3233/JAD-2012-129045  1
2013 Phelix C, LeBaron R, Roberson D, Villareal G, Perry G. P2-003: Flux and metabolite pathway mapping in the aging and Alzheimer's disease hippocampus Alzheimer's & Dementia. 9: P346-P347. DOI: 10.1016/j.jalz.2013.05.645  1
2013 Joseph JA, Casadesus G, Smith MA, Perry G, Shukitt-Hale B. Nutrients and Food Constituents in Cognitive Decline and Neurodegenerative Disease Nutrition in the Prevention and Treatment of Disease. 373-390. DOI: 10.1016/B978-0-12-391884-0.00020-2  1
2013 Bonda DJ, Castellani RJ, Lee HG, Tabaton M, Casadesus G, Perry G, Zhu X, Smith MA. Down syndrome and Alzheimer disease: A "multi-hit" hypothesis based on multiple contributing factors resulting in pleotrophic consequences Alzheimer's Disease Research Compendium. 183-193.  1
2012 Candeias E, Duarte AI, Carvalho C, Correia SC, Cardoso S, Santos RX, Plácido AI, Perry G, Moreira PI. The impairment of insulin signaling in Alzheimer's disease. Iubmb Life. 64: 951-7. PMID 23129399 DOI: 10.1002/iub.1098  1
2012 Miklossy J, Donta S, Mueller K, Nolte O, Perry G. Chronic or late lyme neuroborreliosis: present and future. The Open Neurology Journal. 6: 78. PMID 23091567 DOI: 10.2174/1874205X01206010078  1
2012 Rodrigues R, Smith MA, Wang X, Perry G, Lee HG, Zhu X, Petersen RB. Molecular neuropathogenesis of Alzheimer's disease: an interaction model stressing the central role of oxidative stress. Future Neurology. 7: 287-305. PMID 23086377 DOI: 10.2217/fnl.12.27  1
2012 Castellani RJ, Perry G. Pathogenesis and disease-modifying therapy in Alzheimer's disease: the flat line of progress. Archives of Medical Research. 43: 694-8. PMID 23085451 DOI: 10.1016/j.arcmed.2012.09.009  1
2012 Morelli L, Perry G, Tagliavini F. The contribution of the amyloid hypothesis to the understanding of Alzheimer's disease: a critical overview. International Journal of Alzheimer's Disease. 2012: 709613. PMID 22970405 DOI: 10.1155/2012/709613  1
2012 Greco SJ, Hamzelou A, Johnston JM, Richardson S, Smith MA, Perry G, Ashford JW, Tezapsidis N. Isotyping the human TOMM40 variable-length polymorphism by gene amplification and restriction digest. Current Alzheimer Research. 9: 1168-73. PMID 22950840 DOI: 10.2174/156720512804142921  1
2012 Liu G, Men P, Zhu X, Perry G. Iron chelation and nanoparticle target delivery in the development of new multifunctional disease-modifying drugs for Alzheimer's disease. Therapeutic Delivery. 3: 571-4. PMID 22834400 DOI: 10.4155/tde.12.32  1
2012 Mondragón-Rodríguez S, Perry G, Zhu X, Moreira PI, Williams S. Glycogen synthase kinase 3: a point of integration in Alzheimer's disease and a therapeutic target? International Journal of Alzheimer's Disease. 2012: 276803. PMID 22779025 DOI: 10.1155/2012/276803  1
2012 Piccini A, Borghi R, Guglielmotto M, Tamagno E, Cirmena G, Garuti A, Pollero V, Cammarata S, Fornaro M, Messa M, Colombo L, Salmona M, Perry G, Tabaton M. β-amyloid 1-42 induces physiological transcriptional regulation of BACE1. Journal of Neurochemistry. 122: 1023-31. PMID 22708832 DOI: 10.1111/j.1471-4159.2012.07834.x  1
2012 Wise-Scira O, Xu L, Perry G, Coskuner O. Structures and free energy landscapes of aqueous zinc(II)-bound amyloid-β(1-40) and zinc(II)-bound amyloid-β(1-42) with dynamics. Journal of Biological Inorganic Chemistry : Jbic : a Publication of the Society of Biological Inorganic Chemistry. 17: 927-38. PMID 22674434 DOI: 10.1007/s00775-012-0909-9  1
2012 Nunomura A, Moreira PI, Castellani RJ, Lee HG, Zhu X, Smith MA, Perry G. Oxidative damage to RNA in aging and neurodegenerative disorders. Neurotoxicity Research. 22: 231-48. PMID 22669748 DOI: 10.1007/s12640-012-9331-x  1
2012 Williams WM, Castellani RJ, Weinberg A, Perry G, Smith MA. Do β-defensins and other antimicrobial peptides play a role in neuroimmune function and neurodegeneration? Thescientificworldjournal. 2012: 905785. PMID 22606066 DOI: 10.1100/2012/905785  1
2012 Mondragón-Rodríguez S, Perry G, Zhu X, Boehm J. Amyloid Beta and tau proteins as therapeutic targets for Alzheimer's disease treatment: rethinking the current strategy. International Journal of Alzheimer's Disease. 2012: 630182. PMID 22482074 DOI: 10.1155/2012/630182  1
2012 Castellani RJ, Moreira PI, Perry G, Zhu X. The role of iron as a mediator of oxidative stress in Alzheimer disease. Biofactors (Oxford, England). 38: 133-8. PMID 22447715 DOI: 10.1002/biof.1010  1
2012 Correia SC, Santos RX, Perry G, Zhu X, Moreira PI, Smith MA. Mitochondrial importance in Alzheimer's, Huntington's and Parkinson's diseases. Advances in Experimental Medicine and Biology. 724: 205-21. PMID 22411245 DOI: 10.1007/978-1-4614-0653-2_16  1
2012 Reed-Cossairt A, Zhu X, Lee HG, Reed C, Perry G, Petersen RB. Alzheimer's disease and vascular deficiency: lessons from imaging studies and down syndrome. Current Gerontology and Geriatrics Research. 2012: 929734. PMID 22400025 DOI: 10.1155/2012/929734  1
2012 Perry G, Phelix CF, Nunomura A, Colom LV, Castellani RJ, Petersen RB, Lee HG, Zhu X. Untangling the vascular web from Alzheimer disease and oxidative stress. The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques. 39: 4. PMID 22384486  1
2012 Perry G. Editorial: a new era for medicinal chemistry Mini Reviews in Medicinal Chemistry. 12: 1. PMID 22360667  1
2012 Nunomura A, Tamaoki T, Motohashi N, Nakamura M, McKeel DW, Tabaton M, Lee HG, Smith MA, Perry G, Zhu X. The earliest stage of cognitive impairment in transition from normal aging to Alzheimer disease is marked by prominent RNA oxidation in vulnerable neurons. Journal of Neuropathology and Experimental Neurology. 71: 233-41. PMID 22318126 DOI: 10.1097/NEN.0b013e318248e614  1
2012 Zhu X, Castellani RJ, Ziats NP, Petersen RB, Gon Lee H, Perry G. Mark A. Smith: neurocytochemistry innovator. Journal of Neurochemistry. 120: 1139-40. PMID 22268813 DOI: 10.1111/j.1471-4159.2012.07656.x  1
2012 Bonda DJ, Liu G, Men P, Perry G, Smith MA, Zhu X. Nanoparticle delivery of transition-metal chelators to the brain: Oxidative stress will never see it coming! Cns & Neurological Disorders Drug Targets. 11: 81-5. PMID 22229318  1
2012 Wang X, Yan MH, Fujioka H, Liu J, Wilson-Delfosse A, Chen SG, Perry G, Casadesus G, Zhu X. LRRK2 regulates mitochondrial dynamics and function through direct interaction with DLP1. Human Molecular Genetics. 21: 1931-44. PMID 22228096 DOI: 10.1093/hmg/dds003  1
2012 Santos RX, Correia SC, Zhu X, Lee HG, Petersen RB, Nunomura A, Smith MA, Perry G, Moreira PI. Nuclear and mitochondrial DNA oxidation in Alzheimer's disease. Free Radical Research. 46: 565-76. PMID 22149654 DOI: 10.3109/10715762.2011.648188  1
2012 Zhu X, Castellani RJ, Moreira PI, Aliev G, Shenk JC, Siedlak SL, Harris PL, Fujioka H, Sayre LM, Szweda PA, Szweda LI, Smith MA, Perry G. Hydroxynonenal-generated crosslinking fluorophore accumulation in Alzheimer disease reveals a dichotomy of protein turnover. Free Radical Biology & Medicine. 52: 699-704. PMID 22137893 DOI: 10.1016/j.freeradbiomed.2011.11.004  1
2012 Kudo W, Lee HP, Zou WQ, Wang X, Perry G, Zhu X, Smith MA, Petersen RB, Lee HG. Cellular prion protein is essential for oligomeric amyloid-β-induced neuronal cell death. Human Molecular Genetics. 21: 1138-44. PMID 22100763 DOI: 10.1093/hmg/ddr542  1
2012 Sheng B, Wang X, Su B, Lee HG, Casadesus G, Perry G, Zhu X. Impaired mitochondrial biogenesis contributes to mitochondrial dysfunction in Alzheimer's disease. Journal of Neurochemistry. 120: 419-29. PMID 22077634 DOI: 10.1111/j.1471-4159.2011.07581.x  1
2012 Calderón-Garcidueas L, Kavanaugh M, Block M, D'Angiulli A, Delgado-Chávez R, Torres-Jardón R, González-Maciel A, Reynoso-Robles R, Osnaya N, Villarreal-Calderon R, Guo R, Hua Z, Zhu H, Perry G, Diaz P. Neuroinflammation, hyperphosphorylated tau, diffuse amyloid plaques, and down-regulation of the cellular prion protein in air pollution exposed children and young adults Journal of Alzheimer's Disease. 28: 93-107. PMID 21955814 DOI: 10.3233/JAD-2011-110722  1
2012 Guglielmotto M, Aragno M, Tamagno E, Vercellinatto I, Visentin S, Medana C, Catalano MG, Smith MA, Perry G, Danni O, Boccuzzi G, Tabaton M. AGEs/RAGE complex upregulates BACE1 via NF-κB pathway activation. Neurobiology of Aging. 33: 196.e13-27. PMID 20638753 DOI: 10.1016/j.neurobiolaging.2010.05.026  1
2012 Perry G. Journal of huntington's disease -The family gets bigger Journal of Alzheimer's Disease. 30: 735. DOI: 10.3233/JAD-2012-129909  1
2012 Perry G, Zhu X, Smith MA, Sorensen A, Avila J. Preface: Alzheimer's disease: Advances for a new century Advances in Alzheimer's Disease. 3: 1. DOI: 10.3233/978-1-61499-154-0-1  1
2012 Perry G. A new era for medicinal chemistry Mini-Reviews in Medicinal Chemistry. 12: 1. DOI: 10.2174/138955712798869002  1
2012 Lee HG, Perry G, Zhu X. Mark Smith: Pioneer of Alzheimer disease research Neurotoxicity Research. 22: 181. DOI: 10.1007/s12640-012-9341-8  1
2011 Wise-Scira O, Xu L, Kitahara T, Perry G, Coskuner O. Amyloid-β peptide structure in aqueous solution varies with fragment size. The Journal of Chemical Physics. 135: 205101. PMID 22128957 DOI: 10.1063/1.3662490  1
2011 Colom LV, Castaneda MT, Hernandez S, Perry G, Jaime S, Touhami A. Intrahippocampal amyloid-β (1-40) injections injure medial septal neurons in rats. Current Alzheimer Research. 8: 832-40. PMID 22044024 DOI: 10.2174/156720511798192763  1
2011 Ashford JW, Salehi A, Furst A, Bayley P, Frisoni GB, Jack CR, Sabri O, Adamson MM, Coburn KL, Olichney J, Schuff N, Spielman D, Edland SD, Black S, Rosen A, ... ... Perry G, et al. Imaging the Alzheimer brain. Journal of Alzheimer's Disease : Jad. 26: 1-27. PMID 21971448 DOI: 10.3233/JAD-2011-0073  1
2011 Castellani RJ, Gupta Y, Sheng B, Siedlak SL, Harris PL, Coller JM, Perry G, Lee HG, Tabaton M, Smith MA, Wang X, Zhu X. A novel origin for granulovacuolar degeneration in aging and Alzheimer's disease: parallels to stress granules. Laboratory Investigation; a Journal of Technical Methods and Pathology. 91: 1777-86. PMID 21968813 DOI: 10.1038/labinvest.2011.149  1
2011 Castellani RJ, Petersen RB, Lee HG, Zhu X, Perry G. Mark A. Smith: the scientist, the man. International Journal of Experimental Pathology. 92: 297-8. PMID 21917030 DOI: 10.1111/j.1365-2613.2011.00785.x  1
2011 Liu Q, Xie F, Alvarado-Diaz A, Smith MA, Moreira PI, Zhu X, Perry G. Neurofilamentopathy in neurodegenerative diseases. The Open Neurology Journal. 5: 58-62. PMID 21915226 DOI: 10.2174/1874205X01105010058  1
2011 Bonda DJ, Smith MA, Perry G, Lee HG, Wang X, Zhu X. The mitochondrial dynamics of Alzheimer's disease and Parkinson's disease offer important opportunities for therapeutic intervention. Current Pharmaceutical Design. 17: 3374-80. PMID 21902671 DOI: 10.2174/138161211798072562  1
2011 Correia SC, Cardoso S, Santos RX, Carvalho C, Santos MS, Perry G, Smith MA, Moreira PI. New insights into the mechanisms of mitochondrial preconditioning-triggered neuroprotection. Current Pharmaceutical Design. 17: 3381-9. PMID 21902670 DOI: 10.2174/138161211798072490  1
2011 Stone JG, Casadesus G, Gustaw-Rothenberg K, Siedlak SL, Wang X, Zhu X, Perry G, Castellani RJ, Smith MA. Frontiers in Alzheimer's disease therapeutics. Therapeutic Advances in Chronic Disease. 2: 9-23. PMID 21743833 DOI: 10.1177/2040622310382817  1
2011 Stone JG, Siedlak SL, Tabaton M, Hirano A, Castellani RJ, Santocanale C, Perry G, Smith MA, Zhu X, Lee HG. The cell cycle regulator phosphorylated retinoblastoma protein is associated with tau pathology in several tauopathies. Journal of Neuropathology and Experimental Neurology. 70: 578-87. PMID 21666500 DOI: 10.1097/NEN.0b013e3182204414  1
2011 Wang X, Su B, Liu W, He X, Gao Y, Castellani RJ, Perry G, Smith MA, Zhu X. DLP1-dependent mitochondrial fragmentation mediates 1-methyl-4-phenylpyridinium toxicity in neurons: implications for Parkinson's disease. Aging Cell. 10: 807-23. PMID 21615675 DOI: 10.1111/j.1474-9726.2011.00721.x  1
2011 Bonda DJ, Castellani RJ, Zhu X, Nunomura A, Lee HG, Perry G, Smith MA. A novel perspective on tau in Alzheimer's disease. Current Alzheimer Research. 8: 639-42. PMID 21605042 DOI: 10.2174/156720511796717131  1
2011 Britton GB, Smith MA, Perry G, Sambamurti K, Jagannatha Rao KS. Drug discovery for neurodegenerative diseases: challenges and novel biochemical targets dedicated to the memory of Mark A. Smith for his inspiring contribution to Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 24: 1-2. PMID 21525570 DOI: 10.3233/JAD-2011-110021  1
2011 Valdez CM, Phelix CF, Smith MA, Perry G, Santamaria F. Modeling cholesterol metabolism by gene expression profiling in the hippocampus. Molecular Biosystems. 7: 1891-901. PMID 21451815 DOI: 10.1039/c0mb00282h  1
2011 Perry G, Zhu X. Mark Anthony Smith (1965-2010): Visionary, Alzheimer researcher, and editor-in-chief of the Journal of Alzheimer's Disease. Journal of Alzheimer's Disease : Jad. 24: 1-2. PMID 21383496 DOI: 10.3233/JAD-2011-111437  1
2011 Bonda DJ, Lee HG, Blair JA, Zhu X, Perry G, Smith MA. Role of metal dyshomeostasis in Alzheimer's disease. Metallomics : Integrated Biometal Science. 3: 267-70. PMID 21298161 DOI: 10.1039/c0mt00074d  1
2011 Correia SC, Santos RX, Perry G, Zhu X, Moreira PI, Smith MA. Insulin-resistant brain state: the culprit in sporadic Alzheimer's disease? Ageing Research Reviews. 10: 264-73. PMID 21262392 DOI: 10.1016/j.arr.2011.01.001  1
2011 Phelix CF, LeBaron RG, Roberson DJ, Villanueva RE, Villareal G, Rahimi OB, Siedlak S, Zhu X, Perry G. Transcriptome-To-Metabolome™ Biosimulation Reveals Human Hippocampal Hypometabolism with Age and Alzheimer’s Disease International Journal of Knowledge Discovery in Bioinformatics. 2: 1-18. DOI: 10.4018/jkdb.2011040101  1
2011 Phelix CF, LeBaron RG, Roberson DJ, Villanueva RE, Villareal G, Rahimi OB, Siedlak S, Zhu X, Perry G. Transcriptome-To-Metabolome™ Biosimulation Reveals Human Hippocampal Hypometabolism with Age and Alzheimer’s Disease International Journal of Knowledge Discovery in Bioinformatics. 2: 1-18. DOI: 10.4018/ijkdb.2011040101  1
2011 Castellani RJ, Lee HG, Petersen RB, Zhu X, Perry G. Pathological phenotype in familial neurodegenerative disease: Implications for families and therapeutic constructs Therapy. 8: 475-479. DOI: 10.2217/thy.11.62  1
2011 Castellani RJ, Zhu X, Perry G. Alzheimer's disease therapy: A moving target Therapy. 8: 457-458. DOI: 10.2217/thy.11.56  1
2011 Rothenberg KG, Siedlak SL, Lee HG, Zhu X, Perry G, Smith MA. Neurodegenerative processes in Alzheimer's disease: An overview of pathogenesis with strategic biomarker potential Future Neurology. 6: 173-185. DOI: 10.2217/fnl.10.81  1
2011 Carvalho C, Correia SC, Santos RX, Cardoso S, Moreira PI, Zhu X, Smith MA, Perry G. Association of mitochondrial signaling in Alzheimer's disease and hypoxia Molecular Aspects of Neurodegeneration and Neuroprotection. 50-61. DOI: 10.2174/978160805092511101010050  1
2011 Phelix CF, LeBaron RG, Roberson DJ, Villanueva RE, Villareal G, Rahimi OB, Siedlak S, Zhu X, Perry G. In vivo and in silico evidence: Hippocampal cholesterol metabolism decreases with aging and increases with Alzheimers disease modeling brain aging and disease Proceedings - Ieee International Conference On Data Mining, Icdm. 1064-1070. DOI: 10.1109/ICDMW.2011.98  1
2011 Collins GH, Mondragón-Rodríguez S, Nunomura A, Zhu X, Moreira PI, Smith MA. Oxidative Stress and Balance in Neurodegenerative Diseases Neurodegeneration: the Molecular Pathology of Dementia and Movement Disorders: Second Edition. 10-12. DOI: 10.1002/9781444341256.ch3  0.76
2010 Dwyer BE, Zacharski LR, Balestra DJ, Lerner AJ, Perry G, Zhu X, Smith MA. Potential role of iron in a Mediterranean-style diet. Archives of Neurology. 67: 1286-7; author reply. PMID 20937965 DOI: 10.1001/archneurol.2010.245  1
2010 Borghi R, Piccini A, Barini E, Cirmena G, Guglielmotto M, Tamagno E, Fornaro M, Perry G, Smith MA, Garuti A, Tabaton M. Upregulation of presenilin 1 in brains of sporadic, late-onset Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 22: 771-5. PMID 20847436 DOI: 10.3233/JAD-2010-100729  1
2010 Correia SC, Carvalho C, Cardoso S, Santos RX, Santos MS, Oliveira CR, Perry G, Zhu X, Smith MA, Moreira PI. Mitochondrial preconditioning: a potential neuroprotective strategy. Frontiers in Aging Neuroscience. 2. PMID 20838473 DOI: 10.3389/fnagi.2010.00138  1
2010 Buxton GA, Siedlak SL, Perry G, Smith MA. Mathematical modeling of microtubule dynamics: insights into physiology and disease. Progress in Neurobiology. 92: 478-83. PMID 20713128 DOI: 10.1016/j.pneurobio.2010.08.003  1
2010 Zou WQ, Puoti G, Xiao X, Yuan J, Qing L, Cali I, Shimoji M, Langeveld JP, Castellani R, Notari S, Crain B, Schmidt RE, Geschwind M, Dearmond SJ, Cairns NJ, ... ... Perry G, et al. Variably protease-sensitive prionopathy: a new sporadic disease of the prion protein. Annals of Neurology. 68: 162-72. PMID 20695009 DOI: 10.1002/ana.22094  1
2010 Bonda DJ, Mailankot M, Stone JG, Garrett MR, Staniszewska M, Castellani RJ, Siedlak SL, Zhu X, Lee HG, Perry G, Nagaraj RH, Smith MA. Indoleamine 2,3-dioxygenase and 3-hydroxykynurenine modifications are found in the neuropathology of Alzheimer's disease. Redox Report : Communications in Free Radical Research. 15: 161-8. PMID 20663292 DOI: 10.1179/174329210X12650506623645  1
2010 Storace D, Cammarata S, Borghi R, Sanguineti R, Giliberto L, Piccini A, Pollero V, Novello C, Caltagirone C, Smith MA, Bossù P, Perry G, Odetti P, Tabaton M. Elevation of {beta}-amyloid 1-42 autoantibodies in the blood of amnestic patients with mild cognitive impairment. Archives of Neurology. 67: 867-72. PMID 20625095 DOI: 10.1001/archneurol.2010.137  1
2010 Moreira PI, Santos RX, Zhu X, Lee HG, Smith MA, Casadesus G, Perry G. Autophagy in Alzheimer's disease. Expert Review of Neurotherapeutics. 10: 1209-18. PMID 20586699 DOI: 10.1586/ern.10.84  1
2010 Lee HP, Zhu X, Casadesus G, Castellani RJ, Nunomura A, Smith MA, Lee HG, Perry G. Antioxidant approaches for the treatment of Alzheimer's disease. Expert Review of Neurotherapeutics. 10: 1201-8. PMID 20586698 DOI: 10.1586/ern.10.74  1
2010 Moh CF, Siedlak SL, Tabaton M, Perry G, Castellani RJ, Smith MA. Paraffin-embedded tissue (PET) blot method: application to Alzheimer disease. Journal of Neuroscience Methods. 190: 244-7. PMID 20580647 DOI: 10.1016/j.jneumeth.2010.05.010  1
2010 Correia SC, Santos RX, Perry G, Zhu X, Moreira PI, Smith MA. Mitochondria: the missing link between preconditioning and neuroprotection. Journal of Alzheimer's Disease : Jad. 20: S475-85. PMID 20463394 DOI: 10.3233/JAD-2010-100669  1
2010 Santos RX, Correia SC, Wang X, Perry G, Smith MA, Moreira PI, Zhu X. A synergistic dysfunction of mitochondrial fission/fusion dynamics and mitophagy in Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 20: S401-12. PMID 20463393 DOI: 10.3233/JAD-2010-100666  1
2010 Poeggeler B, Sambamurti K, Siedlak SL, Perry G, Smith MA, Pappolla MA. A novel endogenous indole protects rodent mitochondria and extends rotifer lifespan. Plos One. 5: e10206. PMID 20421998 DOI: 10.1371/journal.pone.0010206  1
2010 Mondragón-Rodríguez S, Basurto-Islas G, Lee HG, Perry G, Zhu X, Castellani RJ, Smith MA. Causes versus effects: the increasing complexities of Alzheimer's disease pathogenesis. Expert Review of Neurotherapeutics. 10: 683-91. PMID 20420489 DOI: 10.1586/ern.10.27  1
2010 Bonda DJ, Wang X, Perry G, Nunomura A, Tabaton M, Zhu X, Smith MA. Oxidative stress in Alzheimer disease: a possibility for prevention. Neuropharmacology. 59: 290-4. PMID 20394761 DOI: 10.1016/j.neuropharm.2010.04.005  1
2010 Gustaw-Rothenberg K, Lerner A, Bonda DJ, Lee HG, Zhu X, Perry G, Smith MA. Biomarkers in Alzheimer's disease: past, present and future. Biomarkers in Medicine. 4: 15-26. PMID 20387301 DOI: 10.2217/bmm.09.86  1
2010 Heath JE, Siedlak SL, Zhu X, Lee HG, Thakur A, Yan R, Perry G, Smith MA, Castellani RJ. Widespread distribution of reticulon-3 in various neurodegenerative diseases. Neuropathology : Official Journal of the Japanese Society of Neuropathology. 30: 574-9. PMID 20374499 DOI: 10.1111/j.1440-1789.2010.01107.x  1
2010 Nakamura M, Shishido N, Nunomura A, Smith MA, Perry G, Akutsu H, Hayashi T. Specific reaction of Met 35 in amyloid beta peptide with hypochlorous acid. Free Radical Research. 44: 734-41. PMID 20370566 DOI: 10.3109/10715761003745954  1
2010 Lee HP, Zhu X, Liu G, Chen SG, Perry G, Smith MA, Lee HG. Divalent metal transporter, iron, and Parkinson's disease: a pathological relationship. Cell Research. 20: 397-9. PMID 20357807 DOI: 10.1038/cr.2010.39  1
2010 Bonda DJ, Wang X, Perry G, Smith MA, Zhu X. Mitochondrial dynamics in Alzheimer's disease: opportunities for future treatment strategies. Drugs & Aging. 27: 181-92. PMID 20210366 DOI: 10.2165/11532140-000000000-00000  1
2010 Nair NG, Perry G, Smith MA, Reddy VP. NMR studies of zinc, copper, and iron binding to histidine, the principal metal ion complexing site of amyloid-beta peptide. Journal of Alzheimer's Disease : Jad. 20: 57-66. PMID 20164601 DOI: 10.3233/JAD-2010-1346  1
2010 Wang X, Perry G, Smith MA, Zhu X. Amyloid-beta-derived diffusible ligands cause impaired axonal transport of mitochondria in neurons. Neuro-Degenerative Diseases. 7: 56-9. PMID 20160460 DOI: 10.1159/000283484  1
2010 Smith MA, Zhu X, Tabaton M, Liu G, McKeel DW, Cohen ML, Wang X, Siedlak SL, Dwyer BE, Hayashi T, Nakamura M, Nunomura A, Perry G. Increased iron and free radical generation in preclinical Alzheimer disease and mild cognitive impairment. Journal of Alzheimer's Disease : Jad. 19: 363-72. PMID 20061651 DOI: 10.3233/JAD-2010-1239  1
2010 Valdez CM, Smith MA, Perry G, Phelix CF, Santamaria F. Cholesterol homeostasis markers are localized to mouse hippocampal pyramidal and granule layers. Hippocampus. 20: 902-5. PMID 20054815 DOI: 10.1002/hipo.20743  1
2010 Nunomura A, Tamaoki T, Tanaka K, Motohashi N, Nakamura M, Hayashi T, Yamaguchi H, Shimohama S, Lee HG, Zhu X, Smith MA, Perry G. Intraneuronal amyloid beta accumulation and oxidative damage to nucleic acids in Alzheimer disease. Neurobiology of Disease. 37: 731-7. PMID 20034567 DOI: 10.1016/j.nbd.2009.12.012  1
2010 Tabaton M, Perry G, Zhu X, Lee HG, Casadesus G, Smith MA. Memantine: "hypothesis testing" not "disease modifying" in Alzheimer's disease. The American Journal of Pathology. 176: 540-1. PMID 20019185 DOI: 10.2353/ajpath.2010.090856  1
2010 Moreira PI, Sayre LM, Zhu X, Nunomura A, Smith MA, Perry G. Detection and localization of markers of oxidative stress by in situ methods: application in the study of Alzheimer disease. Methods in Molecular Biology (Clifton, N.J.). 610: 419-34. PMID 20013193 DOI: 10.1007/978-1-60327-029-8_25  1
2010 Liu G, Men P, Perry G, Smith MA. Nanoparticle and iron chelators as a potential novel Alzheimer therapy. Methods in Molecular Biology (Clifton, N.J.). 610: 123-44. PMID 20013176 DOI: 10.1007/978-1-60327-029-8_8  1
2010 Moreira PI, Carvalho C, Zhu X, Smith MA, Perry G. Mitochondrial dysfunction is a trigger of Alzheimer's disease pathophysiology. Biochimica Et Biophysica Acta. 1802: 2-10. PMID 19853658 DOI: 10.1016/j.bbadis.2009.10.006  1
2010 Moreira PI, Zhu X, Wang X, Lee HG, Nunomura A, Petersen RB, Perry G, Smith MA. Mitochondria: a therapeutic target in neurodegeneration. Biochimica Et Biophysica Acta. 1802: 212-20. PMID 19853657 DOI: 10.1016/j.bbadis.2009.10.007  1
2010 Su B, Wang X, Zheng L, Perry G, Smith MA, Zhu X. Abnormal mitochondrial dynamics and neurodegenerative diseases. Biochimica Et Biophysica Acta. 1802: 135-42. PMID 19799998 DOI: 10.1016/j.bbadis.2009.09.013  1
2010 Tabaton M, Zhu X, Perry G, Smith MA, Giliberto L. Signaling effect of amyloid-beta(42) on the processing of AbetaPP. Experimental Neurology. 221: 18-25. PMID 19747481 DOI: 10.1016/j.expneurol.2009.09.002  1
2010 Zhu X, Beal MF, Wang X, Perry G, Smith MA. Preface: Mitochondria and neurodegenerative diseases Journal of Alzheimer's Disease. 20: S253. DOI: 10.3233/JAD-2010-1424  1
2010 Prakash Reddy V, Perry G, Smith MA. Brain composition: Age-related changes Encyclopedia of Neuroscience. 313-316. DOI: 10.1016/B978-008045046-9.00108-X  1
2010 Rodrigues R, Bonda DJ, Perry G, Castellani RJ, Casadesus G, Lee HG, Lee HP, Wang X, Zhu X, Petersen RB, Smith MA. Oxidative stress and neurodegeneration: An inevitable consequence of aging? Implications for therapy Brain Protection in Schizophrenia, Mood and Cognitive Disorders. 305-323. DOI: 10.1007/978-90-481-8553-5_10  1
2009 Cardoso S, Santos R, Correia S, Carvalho C, Zhu X, Lee HG, Casadesus G, Smith MA, Perry G, Moreira PI. Insulin and Insulin-Sensitizing Drugs in Neurodegeneration: Mitochondria as Therapeutic Targets. Pharmaceuticals (Basel, Switzerland). 2: 250-286. PMID 27713238 DOI: 10.3390/ph2030250  1
2009 Friedlich AL, Rolston RK, Zhu X, Marlatt MW, Castellani RJ, Nunomura A, Lee HG, Casadesus G, Perry G, Smith MA. Treatment advances in Alzheimer's disease based on the oxidative stress model. F1000 Medicine Reports. 1. PMID 20948726 DOI: 10.3410/M1-54  1
2009 Bonda DJ, Wang X, Gustaw-Rothenberg KA, Perry G, Smith MA, Zhu X. Mitochondrial Drugs for Alzheimer Disease. Pharmaceuticals (Basel, Switzerland). 2: 287-298. PMID 20657666 DOI: 10.3390/ph2030287  1
2009 Liu G, Men P, Perry G, Smith MA. Chapter 5 - Development of iron chelator-nanoparticle conjugates as potential therapeutic agents for Alzheimer disease. Progress in Brain Research. 180: 97-108. PMID 20302830 DOI: 10.1016/S0079-6123(08)80005-2  1
2009 Perry G, Moreira PI, Siedlak SL, Nunomura A, Zhu X, Smith MA. Natural oxidant balance in Parkinson disease. Archives of Neurology. 66: 1445. PMID 20008647 DOI: 10.1001/archneurol.2009.261  1
2009 Bonda DJ, Evans TA, Santocanale C, Llosá JC, Viña J, Bajic V, Castellani RJ, Siedlak SL, Perry G, Smith MA, Lee HG. Evidence for the progression through S-phase in the ectopic cell cycle re-entry of neurons in Alzheimer disease. Aging. 1: 382-8. PMID 19946466 DOI: 10.18632/AGING.100044  1
2009 Liu G, Men P, Perry G, Smith MA. Metal chelators coupled with nanoparticles as potential therapeutic agents for Alzheimer's disease. Journal of Nanoneuroscience. 1: 42-55. PMID 19936278 DOI: 10.1166/JNS.2009.005  1
2009 Lee HP, Casadesus G, Zhu X, Lee HG, Perry G, Smith MA, Gustaw-Rothenberg K, Lerner A. All-trans retinoic acid as a novel therapeutic strategy for Alzheimer's disease. Expert Review of Neurotherapeutics. 9: 1615-21. PMID 19903021 DOI: 10.1586/ern.09.86  1
2009 Crain BJ, Terry RD, Perry G. 2009 award recipients--Peter C. Burger, MD, Pierluigi Gambetti, MD, and Nicholas K. Gonatas, MD. Journal of Neuropathology and Experimental Neurology. 68: 1244-6. PMID 19901633 DOI: 10.1097/NEN.0b013e3181bfa55e  1
2009 Su B, Liu H, Wang X, Chen SG, Siedlak SL, Kondo E, Choi R, Takeda A, Castellani RJ, Perry G, Smith MA, Zhu X, Lee HG. Ectopic localization of FOXO3a protein in Lewy bodies in Lewy body dementia and Parkinson's disease. Molecular Neurodegeneration. 4: 32. PMID 19627592 DOI: 10.1186/1750-1326-4-32  1
2009 Wang X, Su B, Lee HG, Li X, Perry G, Smith MA, Zhu X. Impaired balance of mitochondrial fission and fusion in Alzheimer's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 9090-103. PMID 19605646 DOI: 10.1523/JNEUROSCI.1357-09.2009  1
2009 Castellani RJ, Lee HG, Siedlak SL, Nunomura A, Hayashi T, Nakamura M, Zhu X, Perry G, Smith MA. Reexamining Alzheimer's disease: evidence for a protective role for amyloid-beta protein precursor and amyloid-beta. Journal of Alzheimer's Disease : Jad. 18: 447-52. PMID 19584435 DOI: 10.3233/JAD-2009-1151  1
2009 Cardoso S, Correia S, Santos RX, Carvalho C, Santos MS, Oliveira CR, Perry G, Smith MA, Zhu X, Moreira PI. Insulin is a two-edged knife on the brain. Journal of Alzheimer's Disease : Jad. 18: 483-507. PMID 19542630 DOI: 10.3233/JAD-2009-1155  1
2009 Dwyer BE, Smith MA, Richardson SL, Perry G, Zhu X. Down-regulation of aminolevulinate synthase, the rate-limiting enzyme for heme biosynthesis in Alzheimer's disease. Neuroscience Letters. 460: 180-4. PMID 19477221 DOI: 10.1016/j.neulet.2009.05.058  1
2009 Perez M, Santa-Maria I, Gomez de Barreda E, Zhu X, Cuadros R, Cabrero JR, Sanchez-Madrid F, Dawson HN, Vitek MP, Perry G, Smith MA, Avila J. Tau--an inhibitor of deacetylase HDAC6 function. Journal of Neurochemistry. 109: 1756-66. PMID 19457097 DOI: 10.1111/j.1471-4159.2009.06102.x  1
2009 Liu G, Men P, Kudo W, Perry G, Smith MA. Nanoparticle-chelator conjugates as inhibitors of amyloid-beta aggregation and neurotoxicity: a novel therapeutic approach for Alzheimer disease. Neuroscience Letters. 455: 187-90. PMID 19429118 DOI: 10.1016/j.neulet.2009.03.064  1
2009 Castellani RJ, Zhu X, Lee HG, Smith MA, Perry G. Molecular pathogenesis of Alzheimer's disease: reductionist versus expansionist approaches. International Journal of Molecular Sciences. 10: 1386-406. PMID 19399255 DOI: 10.3390/ijms10031386  1
2009 Wang X, Su B, Zheng L, Perry G, Smith MA, Zhu X. The role of abnormal mitochondrial dynamics in the pathogenesis of Alzheimer's disease. Journal of Neurochemistry. 109: 153-9. PMID 19393022 DOI: 10.1111/j.1471-4159.2009.05867.x  1
2009 Reddy VP, Zhu X, Perry G, Smith MA. Oxidative stress in diabetes and Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 16: 763-74. PMID 19387111 DOI: 10.3233/JAD-2009-1013  1
2009 Tezapsidis N, Johnston JM, Smith MA, Ashford JW, Casadesus G, Robakis NK, Wolozin B, Perry G, Zhu X, Greco SJ, Sarkar S. Leptin: a novel therapeutic strategy for Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 16: 731-40. PMID 19387109 DOI: 10.3233/JAD-2009-1021  1
2009 Obrenovich ME, Morales LA, Cobb CJ, Shenk JC, Méndez GM, Fischbach K, Smith MA, Qasimov EK, Perry G, Aliev G. Insights into cerebrovascular complications and Alzheimer disease through the selective loss of GRK2 regulation. Journal of Cellular and Molecular Medicine. 13: 853-65. PMID 19292735 DOI: 10.1111/j.1582-4934.2008.00512.x  1
2009 Nunomura A, Hofer T, Moreira PI, Castellani RJ, Smith MA, Perry G. RNA oxidation in Alzheimer disease and related neurodegenerative disorders. Acta Neuropathologica. 118: 151-66. PMID 19271225 DOI: 10.1007/s00401-009-0508-1  1
2009 Perry G, Zhu X, Moreira PI, Smith MA. Altered redox balance in disease: can we change the new equilibria? Annals of Neurology. 65: 121-3. PMID 19259960 DOI: 10.1002/ana.21608  1
2009 Rajendran R, Minqin R, Ynsa MD, Casadesus G, Smith MA, Perry G, Halliwell B, Watt F. A novel approach to the identification and quantitative elemental analysis of amyloid deposits--insights into the pathology of Alzheimer's disease. Biochemical and Biophysical Research Communications. 382: 91-5. PMID 19258010 DOI: 10.1016/j.bbrc.2009.02.136  1
2009 Guglielmotto M, Aragno M, Autelli R, Giliberto L, Novo E, Colombatto S, Danni O, Parola M, Smith MA, Perry G, Tamagno E, Tabaton M. The up-regulation of BACE1 mediated by hypoxia and ischemic injury: role of oxidative stress and HIF1alpha. Journal of Neurochemistry. 108: 1045-56. PMID 19196431 DOI: 10.1111/j.1471-4159.2008.05858.x  1
2009 Dwyer BE, Zacharski LR, Balestra DJ, Lerner AJ, Perry G, Zhu X, Smith MA. Getting the iron out: phlebotomy for Alzheimer's disease? Medical Hypotheses. 72: 504-9. PMID 19195795 DOI: 10.1016/j.mehy.2008.12.029  1
2009 Lee HP, Zhu X, Zhu X, Skidmore SC, Perry G, Sayre LM, Smith MA, Lee HG. The essential role of ERK in 4-oxo-2-nonenal-mediated cytotoxicity in SH-SY5Y human neuroblastoma cells. Journal of Neurochemistry. 108: 1434-41. PMID 19183271 DOI: 10.1111/j.1471-4159.2009.05883.x  1
2009 Lee HG, Casadesus G, Nunomura A, Zhu X, Castellani RJ, Richardson SL, Perry G, Felsher DW, Petersen RB, Smith MA. The neuronal expression of MYC causes a neurodegenerative phenotype in a novel transgenic mouse. The American Journal of Pathology. 174: 891-7. PMID 19164506 DOI: 10.2353/ajpath.2009.080583  1
2009 Siedlak SL, Casadesus G, Webber KM, Pappolla MA, Atwood CS, Smith MA, Perry G. Chronic antioxidant therapy reduces oxidative stress in a mouse model of Alzheimer's disease. Free Radical Research. 43: 156-64. PMID 19160110 DOI: 10.1080/10715760802644694  1
2009 Aliev G, Liu J, Shenk JC, Fischbach K, Pacheco GJ, Chen SG, Obrenovich ME, Ward WF, Richardson AG, Smith MA, Gasimov E, Perry G, Ames BN. Neuronal mitochondrial amelioration by feeding acetyl-L-carnitine and lipoic acid to aged rats. Journal of Cellular and Molecular Medicine. 13: 320-33. PMID 18373733 DOI: 10.1111/j.1582-4934.2008.00324.x  1
2009 Castellani RJ, Perry G, Smith MA. Is Alzheimer's disease a myth? When is disease a disease? Current Alzheimer Research. 6: 82. DOI: 10.2174/156720509787313925  1
2009 Casadesus G, Bryan KJ, Perry G, Smith MA. Involvement of gonadotropins in cognitive function: Implications for Alzheimer's disease Hormones, Cognition and Dementia: State of the Art and Emergent Therapeutic Strategies. 251-258. DOI: 10.1017/CBO9780511635700.027  1
2009 Nunomura A, Takeda A, Moreira PI, Castellani RJ, Lee HG, Zhu X, Smith MA, Perry G. Neurofibrillary tangle formation as a protective response to oxidative stress in Alzheimer's disease Current Hypotheses and Research Milestones in Alzheimer's Disease. 103-113. DOI: 10.1007/978-0-387-87995-6_9  1
2009 Maccioni RB, Perry G. Preface Current Hypotheses and Research Milestones in Alzheimer's Disease. v-vi. DOI: 10.1007/978-0-387-87995-6  1
2008 Myung NH, Zhu X, Kruman II, Castellani RJ, Petersen RB, Siedlak SL, Perry G, Smith MA, Lee HG. Evidence of DNA damage in Alzheimer disease: phosphorylation of histone H2AX in astrocytes. Age (Dordrecht, Netherlands). 30: 209-15. PMID 19424844 DOI: 10.1007/s11357-008-9050-7  1
2008 Castellani RJ, Nunomura A, Rolston RK, Moreira PI, Takeda A, Perry G, Smith MA. Sublethal RNA oxidation as a mechanism for neurodegenerative disease. International Journal of Molecular Sciences. 9: 789-806. PMID 19325784 DOI: 10.3390/ijms9050789  1
2008 Pallas M, Camins A, Smith MA, Perry G, Lee HG, Casadesus G. From aging to Alzheimer's disease: unveiling "the switch" with the senescence-accelerated mouse model (SAMP8). Journal of Alzheimer's Disease : Jad. 15: 615-24. PMID 19096160 DOI: 10.3233/JAD-2008-15408  1
2008 Su B, Wang X, Nunomura A, Moreira PI, Lee HG, Perry G, Smith MA, Zhu X. Oxidative stress signaling in Alzheimer's disease. Current Alzheimer Research. 5: 525-32. PMID 19075578 DOI: 10.2174/156720508786898451  1
2008 Aliev G, Obrenovich ME, Reddy VP, Shenk JC, Moreira PI, Nunomura A, Zhu X, Smith MA, Perry G. Antioxidant therapy in Alzheimer's disease: theory and practice. Mini Reviews in Medicinal Chemistry. 8: 1395-406. PMID 18991755 DOI: 10.2174/138955708786369582  1
2008 Marlatt MW, Lucassen PJ, Perry G, Smith MA, Zhu X. Alzheimer's disease: cerebrovascular dysfunction, oxidative stress, and advanced clinical therapies. Journal of Alzheimer's Disease : Jad. 15: 199-210. PMID 18953109 DOI: 10.3233/JAD-2008-15206  1
2008 Aliev G, Gasimov E, Obrenovich ME, Fischbach K, Shenk JC, Smith MA, Perry G. Atherosclerotic lesions and mitochondria DNA deletions in brain microvessels: implication in the pathogenesis of Alzheimer's disease. Vascular Health and Risk Management. 4: 721-30. PMID 18827923  1
2008 Bryan KJ, Zhu X, Harris PL, Perry G, Castellani RJ, Smith MA, Casadesus G. Expression of CD74 is increased in neurofibrillary tangles in Alzheimer's disease. Molecular Neurodegeneration. 3: 13. PMID 18786268 DOI: 10.1186/1750-1326-3-13  1
2008 Castellani RJ, Nunomura A, Lee HG, Perry G, Smith MA. Phosphorylated tau: toxic, protective, or none of the above. Journal of Alzheimer's Disease : Jad. 14: 377-83. PMID 18688087 DOI: 10.3233/JAD-2008-14404  1
2008 Aliev G, Shenk JC, Fischbach K, Perry G. Stem cell niches as clinical targets: the future of anti-ischemic therapy? Nature Clinical Practice. Cardiovascular Medicine. 5: 590-1. PMID 18628773 DOI: 10.1038/ncpcardio1295  1
2008 Collingwood JF, Chong RK, Kasama T, Cervera-Gontard L, Dunin-Borkowski RE, Perry G, Pósfai M, Siedlak SL, Simpson ET, Smith MA, Dobson J. Three-dimensional tomographic imaging and characterization of iron compounds within Alzheimer's plaque core material. Journal of Alzheimer's Disease : Jad. 14: 235-45. PMID 18560134  1
2008 Castellani RJ, Lee HG, Zhu X, Perry G, Smith MA. Alzheimer disease pathology as a host response. Journal of Neuropathology and Experimental Neurology. 67: 523-31. PMID 18520771 DOI: 10.1097/NEN.0b013e318177eaf4  1
2008 Friedland RP, Tedesco JM, Wilson AC, Atwood CS, Smith MA, Perry G, Zagorski MG. Antibodies to potato virus Y bind the amyloid beta peptide: immunohistochemical and NMR studies. The Journal of Biological Chemistry. 283: 22550-6. PMID 18505725 DOI: 10.1074/jbc.M802088200  1
2008 Gustaw KA, Garrett MR, Lee HG, Castellani RJ, Zagorski MG, Prakasam A, Siedlak SL, Zhu X, Perry G, Petersen RB, Friedland RP, Smith MA. Antigen-antibody dissociation in Alzheimer disease: a novel approach to diagnosis. Journal of Neurochemistry. 106: 1350-6. PMID 18485104 DOI: 10.1111/j.1471-4159.2008.05477.x  1
2008 Casadesus G, Rolston RK, Webber KM, Atwood CS, Bowen RL, Perry G, Smith MA. Menopause, estrogen, and gonadotropins in Alzheimer's disease. Advances in Clinical Chemistry. 45: 139-53. PMID 18429496 DOI: 10.1016/S0065-2423(07)00006-6  1
2008 Shah RS, Lee HG, Xiongwei Z, Perry G, Smith MA, Castellani RJ. Current approaches in the treatment of Alzheimer's disease. Biomedicine & Pharmacotherapy = BioméDecine & PharmacothéRapie. 62: 199-207. PMID 18407457 DOI: 10.1016/j.biopha.2008.02.005  1
2008 Mondragón-Rodríguez S, Basurto-Islas G, Santa-Maria I, Mena R, Binder LI, Avila J, Smith MA, Perry G, García-Sierra F. Cleavage and conformational changes of tau protein follow phosphorylation during Alzheimer's disease. International Journal of Experimental Pathology. 89: 81-90. PMID 18336525 DOI: 10.1111/j.1365-2613.2007.00568.x  1
2008 Perry G, Zhu X, Babar AK, Siedlak SL, Yang Q, Ito G, Iwatsubo T, Smith MA, Chen SG. Leucine-rich repeat kinase 2 colocalizes with alpha-synuclein in Parkinson's disease, but not tau-containing deposits in tauopathies. Neuro-Degenerative Diseases. 5: 222-4. PMID 18322396 DOI: 10.1159/000113708  1
2008 Moreira PI, Santos MS, Oliveira CR, Shenk JC, Nunomura A, Smith MA, Zhu X, Perry G. Alzheimer disease and the role of free radicals in the pathogenesis of the disease. Cns & Neurological Disorders Drug Targets. 7: 3-10. PMID 18289026 DOI: 10.2174/187152708783885156  1
2008 Su B, Wang X, Drew KL, Perry G, Smith MA, Zhu X. Physiological regulation of tau phosphorylation during hibernation. Journal of Neurochemistry. 105: 2098-108. PMID 18284615 DOI: 10.1111/j.1471-4159.2008.05294.x  1
2008 Gonzalez-Cuyar LF, Perry G, Miyajima H, Atwood CS, Riveros-Angel M, Lyons PF, Siedlak SL, Smith MA, Castellani RJ. Redox active iron accumulation in aceruloplasminemia. Neuropathology : Official Journal of the Japanese Society of Neuropathology. 28: 466-71. PMID 18282164 DOI: 10.1111/j.1440-1789.2008.00901.x  1
2008 Moreira PI, Nunomura A, Nakamura M, Takeda A, Shenk JC, Aliev G, Smith MA, Perry G. Nucleic acid oxidation in Alzheimer disease. Free Radical Biology & Medicine. 44: 1493-505. PMID 18258207 DOI: 10.1016/j.freeradbiomed.2008.01.002  1
2008 Sayre LM, Perry G, Smith MA. Oxidative stress and neurotoxicity. Chemical Research in Toxicology. 21: 172-88. PMID 18052107 DOI: 10.1021/tx700210j  1
2008 Zhu X, Siedlak SL, Wang Y, Perry G, Castellani RJ, Cohen ML, Smith MA. Neuronal binucleation in Alzheimer disease hippocampus. Neuropathology and Applied Neurobiology. 34: 457-65. PMID 17995921 DOI: 10.1111/j.1365-2990.2007.00908.x  1
2008 Gonzalez-Cuyar LF, Morrison AL, Perry G, DeJong JJ, Smith MA, Castellani RJ. Cerebrotendinous xanthomatosis: A critical update Future Neurology. 3: 491-501. DOI: 10.2217/14796708.3.4.491  1
2008 Bryan K, Lee HG, Perry G, Castellani RJ, Smith MA, Casadesus G. Nonestrogen-based hormonal therapies for Alzheimer's disease Future Neurology. 3: 399-407. DOI: 10.2217/14796708.3.4.399  1
2007 Webber KM, Casadesus G, Bowen RL, Perry G, Smith MA. Evidence for the role of luteinizing hormone in Alzheimer disease. Endocrine, Metabolic & Immune Disorders Drug Targets. 7: 300-3. PMID 18220951 DOI: 10.2174/187153007782794326  1
2007 Nunomura A, Moreira PI, Lee HG, Zhu X, Castellani RJ, Smith MA, Perry G. Neuronal death and survival under oxidative stress in Alzheimer and Parkinson diseases. Cns & Neurological Disorders Drug Targets. 6: 411-23. PMID 18220780 DOI: 10.2174/187152707783399201  1
2007 Nunomura A, Moreira PI, Takeda A, Smith MA, Perry G. Oxidative RNA damage and neurodegeneration. Current Medicinal Chemistry. 14: 2968-75. PMID 18220733 DOI: 10.2174/092986707782794078  1
2007 Castellani RJ, Perry G, Smith MA. The role of novel chitin-like polysaccharides in Alzheimer disease. Neurotoxicity Research. 12: 269-74. PMID 18201954 DOI: 10.1007/BF03033910  1
2007 Webber KM, Perry G, Smith MA, Casadesus G. The contribution of luteinizing hormone to Alzheimer disease pathogenesis. Clinical Medicine & Research. 5: 177-83. PMID 18056027 DOI: 10.3121/cmr.2007.741  1
2007 Wang X, Su B, Perry G, Smith MA, Zhu X. Insights into amyloid-beta-induced mitochondrial dysfunction in Alzheimer disease. Free Radical Biology & Medicine. 43: 1569-73. PMID 18037122 DOI: 10.1016/j.freeradbiomed.2007.09.007  1
2007 Bishop GM, Smith MA, LaManna JC, Wilson AC, Perry G, Atwood CS. Iron homeostasis is maintained in the brain, but not the liver, following mild hypoxia. Redox Report : Communications in Free Radical Research. 12: 257-66. PMID 17961297 DOI: 10.1179/135100007X239270  1
2007 Nakamura M, Shishido N, Nunomura A, Smith MA, Perry G, Hayashi Y, Nakayama K, Hayashi T. Three histidine residues of amyloid-beta peptide control the redox activity of copper and iron. Biochemistry. 46: 12737-43. PMID 17929832 DOI: 10.1021/bi701079z  1
2007 Moreira PI, Harris PL, Zhu X, Santos MS, Oliveira CR, Smith MA, Perry G. Lipoic acid and N-acetyl cysteine decrease mitochondrial-related oxidative stress in Alzheimer disease patient fibroblasts. Journal of Alzheimer's Disease : Jad. 12: 195-206. PMID 17917164 DOI: 10.3233/JAD-2007-12210  1
2007 Liu Q, Ju WK, Crowston JG, Xie F, Perry G, Smith MA, Lindsey JD, Weinreb RN. Oxidative stress is an early event in hydrostatic pressure induced retinal ganglion cell damage. Investigative Ophthalmology & Visual Science. 48: 4580-9. PMID 17898281 DOI: 10.1167/iovs.07-0170  1
2007 Moreira PI, Siedlak SL, Wang X, Santos MS, Oliveira CR, Tabaton M, Nunomura A, Szweda LI, Aliev G, Smith MA, Zhu X, Perry G. Increased autophagic degradation of mitochondria in Alzheimer disease. Autophagy. 3: 614-5. PMID 17786024 DOI: 10.4161/auto.4872  1
2007 Gonzalez-Cuyar LF, Hunter B, Harris PL, Perry G, Smith MA, Castellani RJ. Cerebrotendinous xanthomatosis: case report with evidence of oxidative stress. Redox Report : Communications in Free Radical Research. 12: 119-24. PMID 17623518 DOI: 10.1179/135100007X200173  1
2007 Moreira PI, Siedlak SL, Wang X, Santos MS, Oliveira CR, Tabaton M, Nunomura A, Szweda LI, Aliev G, Smith MA, Zhu X, Perry G. Autophagocytosis of mitochondria is prominent in Alzheimer disease. Journal of Neuropathology and Experimental Neurology. 66: 525-32. PMID 17549012 DOI: 10.1097/01.jnen.0000240476.73532.b0  1
2007 Petersen RB, Nunomura A, Lee HG, Casadesus G, Perry G, Smith MA, Zhu X. Signal transduction cascades associated with oxidative stress in Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 11: 143-52. PMID 17522439 DOI: 10.3233/JAD-2007-11202  1
2007 Castellani RJ, Moreira PI, Liu G, Dobson J, Perry G, Smith MA, Zhu X. Iron: the Redox-active center of oxidative stress in Alzheimer disease. Neurochemical Research. 32: 1640-5. PMID 17508283 DOI: 10.1007/s11064-007-9360-7  1
2007 Evans TA, Raina AK, Delacourte A, Aprelikova O, Lee HG, Zhu X, Perry G, Smith MA. BRCA1 may modulate neuronal cell cycle re-entry in Alzheimer disease. International Journal of Medical Sciences. 4: 140-5. PMID 17505559  1
2007 Castellani RJ, Zhu X, Lee HG, Moreira PI, Perry G, Smith MA. Neuropathology and treatment of Alzheimer disease: did we lose the forest for the trees? Expert Review of Neurotherapeutics. 7: 473-85. PMID 17492899 DOI: 10.1586/14737175.7.5.473  1
2007 Zhu X, Avila J, Perry G, Smith MA. Treating the lesions, not the disease. The American Journal of Pathology. 170: 1457-9. PMID 17456753 DOI: 10.2353/ajpath.2007.070193  1
2007 Thakur A, Wang X, Siedlak SL, Perry G, Smith MA, Zhu X. c-Jun phosphorylation in Alzheimer disease. Journal of Neuroscience Research. 85: 1668-73. PMID 17455299 DOI: 10.1002/jnr.21298  1
2007 Zhu X, Smith MA, Honda K, Aliev G, Moreira PI, Nunomura A, Casadesus G, Harris PL, Siedlak SL, Perry G. Vascular oxidative stress in Alzheimer disease. Journal of the Neurological Sciences. 257: 240-6. PMID 17337008 DOI: 10.1016/j.jns.2007.01.039  1
2007 Wung JK, Perry G, Kowalski A, Harris PL, Bishop GM, Trivedi MA, Johnson SC, Smith MA, Denhardt DT, Atwood CS. Increased expression of the remodeling- and tumorigenic-associated factor osteopontin in pyramidal neurons of the Alzheimer's disease brain. Current Alzheimer Research. 4: 67-72. PMID 17316167 DOI: 10.2174/156720507779939869  1
2007 Liu Q, Xie F, Rolston R, Moreira PI, Nunomura A, Zhu X, Smith MA, Perry G. Prevention and treatment of Alzheimer disease and aging: antioxidants. Mini Reviews in Medicinal Chemistry. 7: 171-80. PMID 17305591 DOI: 10.2174/138955707779802552  1
2007 Casadesus G, Smith MA, Basu S, Hua J, Capobianco DE, Siedlak SL, Zhu X, Perry G. Increased isoprostane and prostaglandin are prominent in neurons in Alzheimer disease. Molecular Neurodegeneration. 2: 2. PMID 17241462 DOI: 10.1186/1750-1326-2-2  1
2007 Lee HG, Zhu X, Castellani RJ, Nunomura A, Perry G, Smith MA. Amyloid-beta in Alzheimer disease: the null versus the alternate hypotheses. The Journal of Pharmacology and Experimental Therapeutics. 321: 823-9. PMID 17229880 DOI: 10.1124/jpet.106.114009  1
2007 Zhu X, Lee HG, Perry G, Smith MA. Alzheimer disease, the two-hit hypothesis: an update. Biochimica Et Biophysica Acta. 1772: 494-502. PMID 17142016 DOI: 10.1016/j.bbadis.2006.10.014  1
2007 Previll LA, Crosby ME, Castellani RJ, Bowser R, Perry G, Smith MA, Zhu X. Increased expression of p130 in Alzheimer disease. Neurochemical Research. 32: 639-44. PMID 17006760 DOI: 10.1007/s11064-006-9146-3  1
2007 Nunomura A, Perry G, Smith MA. Prospects for antioxidant therapy in mild cognitive impairment and alzheimer's disease Oxidative Stress and Neurodegenerative Disorders. 451-466. DOI: 10.1016/B978-044452809-4/50161-7  1
2007 Moreira PI, Nunomura A, Honda K, Aliev G, Casadesus G, Zhu X, Smith MA, Perry G. The key role of oxidative stress in alzheimer's disease Oxidative Stress and Neurodegenerative Disorders. 267-281. DOI: 10.1016/B978-044452809-4/50153-8  1
2007 Moreira PI, Smith MA, Zhu X, Nunomura A, Perry G. The potential application of antioxidant agents in Alzheimer disease therapeutics Pharmacological Mechanisms in Alzheimer's Therapeutics. 194-211. DOI: 10.1007/978-0-387-71522-3_12  1
2006 Smith MA, Zhu X, Lee HG, Harris PL, Fortino AE, Perry G, Castellani RJ. Sequestration of p27 within the cytoplasm of cardiac myocytes in chronic ischemic heart disease: pathogenic implications for ischemic cardiomyopathy. Age (Dordrecht, Netherlands). 28: 85-91. PMID 23598681 DOI: 10.1007/s11357-006-9001-0  1
2006 Zhu X, Babar A, Siedlak SL, Yang Q, Ito G, Iwatsubo T, Smith MA, Perry G, Chen SG. LRRK2 in Parkinson's disease and dementia with Lewy bodies. Molecular Neurodegeneration. 1: 17. PMID 17137507 DOI: 10.1186/1750-1326-1-17  1
2006 Nunomura A, Honda K, Takeda A, Hirai K, Zhu X, Smith MA, Perry G. Oxidative damage to RNA in neurodegenerative diseases. Journal of Biomedicine & Biotechnology. 2006: 82323. PMID 17047315 DOI: 10.1155/JBB/2006/82323  1
2006 Casadesus G, Puig ER, Webber KM, Atwood CS, Escuer MC, Bowen RL, Perry G, Smith MA. Targeting gonadotropins: an alternative option for Alzheimer disease treatment. Journal of Biomedicine & Biotechnology. 2006: 39508. PMID 17047306 DOI: 10.1155/JBB/2006/39508  1
2006 Dwyer BE, Stone ML, Zhu X, Perry G, Smith MA. Heme deficiency in Alzheimer's disease: a possible connection to porphyria. Journal of Biomedicine & Biotechnology. 2006: 24038. PMID 17047301 DOI: 10.1155/JBB/2006/24038  1
2006 Webber KM, Stocco DM, Casadesus G, Bowen RL, Atwood CS, Previll LA, Harris PL, Zhu X, Perry G, Smith MA. Steroidogenic acute regulatory protein (StAR): evidence of gonadotropin-induced steroidogenesis in Alzheimer disease. Molecular Neurodegeneration. 1: 14. PMID 17018137 DOI: 10.1186/1750-1326-1-14  1
2006 Zhu X, Raina AK, Perry G, Smith MA. Apoptosis in Alzheimer disease: a mathematical improbability. Current Alzheimer Research. 3: 393-6. PMID 17017869 DOI: 10.2174/156720506778249470  1
2006 Obrenovich ME, Smith MA, Siedlak SL, Chen SG, de la Torre JC, Perry G, Aliev G. Overexpression of GRK2 in Alzheimer disease and in a chronic hypoperfusion rat model is an early marker of brain mitochondrial lesions. Neurotoxicity Research. 10: 43-56. PMID 17000469 DOI: 10.1007/BF03033333  1
2006 Lee HG, Ueda M, Zhu X, Perry G, Smith MA. Ectopic expression of phospho-Smad2 in Alzheimer's disease: uncoupling of the transforming growth factor-beta pathway? Journal of Neuroscience Research. 84: 1856-61. PMID 16998902 DOI: 10.1002/jnr.21072  1
2006 Lam-Himlin D, Espey MG, Perry G, Smith MA, Castellani RJ. Malignant glioma progression and nitric oxide. Neurochemistry International. 49: 764-8. PMID 16971023 DOI: 10.1016/j.neuint.2006.07.001  1
2006 Lee HG, Zhu X, Nunomura A, Perry G, Smith MA. Amyloid-beta vaccination: testing the amyloid hypothesis?: heads we win, tails you lose! The American Journal of Pathology. 169: 738-9. PMID 16936250 DOI: 10.2353/ajpath.2006.060633  1
2006 Zhu X, Perry G, Moreira PI, Aliev G, Cash AD, Hirai K, Smith MA. Mitochondrial abnormalities and oxidative imbalance in Alzheimer disease. Journal of Alzheimer's Disease : Jad. 9: 147-53. PMID 16873962 DOI: 10.3233/JAD-2006-9207  1
2006 Zhu X, Siedlak SL, Smith MA, Perry G, Chen SG. LRRK2 protein is a component of Lewy bodies. Annals of Neurology. 60: 617-8; author reply . PMID 16847950 DOI: 10.1002/ana.20928  1
2006 Nunomura A, Castellani RJ, Zhu X, Moreira PI, Perry G, Smith MA. Involvement of oxidative stress in Alzheimer disease. Journal of Neuropathology and Experimental Neurology. 65: 631-41. PMID 16825950 DOI: 10.1097/01.jnen.0000228136.58062.bf  1
2006 Lee HG, Perry G, Zhu X, Nunomura A, Smith MA. Amyloid-beta, BACE, and oxidative stress in Alzheimer's disease, a commentary on "The different aggregation state of beta-amyloid 1-42 mediates different effects on oxidative stress, neurodegeneration and BACE-1 expression". Free Radical Biology & Medicine. 41: 188-9. PMID 16814097 DOI: 10.1016/j.freeradbiomed.2006.03.014  1
2006 Moreira PI, Zhu X, Nunomura A, Smith MA, Perry G. Therapeutic options in Alzheimer's disease. Expert Review of Neurotherapeutics. 6: 897-910. PMID 16784412 DOI: 10.1586/14737175.6.6.897  1
2006 Lee HG, Zhu X, Takeda A, Perry G, Smith MA. Emerging evidence for the neuroprotective role of alpha-synuclein. Experimental Neurology. 200: 1-7. PMID 16780837 DOI: 10.1016/j.expneurol.2006.04.024  1
2006 Casadesus G, Garrett MR, Webber KM, Hartzler AW, Atwood CS, Perry G, Bowen RL, Smith MA. The estrogen myth: potential use of gonadotropin-releasing hormone agonists for the treatment of Alzheimer's disease. Drugs in R&D. 7: 187-93. PMID 16752944 DOI: 10.2165/00126839-200607030-00004  1
2006 Castellani RJ, Lee HG, Zhu X, Nunomura A, Perry G, Smith MA. Neuropathology of Alzheimer disease: pathognomonic but not pathogenic. Acta Neuropathologica. 111: 503-9. PMID 16718346 DOI: 10.1007/s00401-006-0071-y  1
2006 Nunomura A, Castellani RJ, Lee HG, Moreira PI, Zhu X, Perry G, Smith MA. Neuropathology in Alzheimer's disease: awaking from a hundred-year-old dream. Science of Aging Knowledge Environment : Sage Ke. 2006: pe10. PMID 16672726 DOI: 10.1126/sageke.2006.8.pe10  1
2006 Castellani RJ, Lee HG, Perry G, Smith MA. Antioxidant protection and neurodegenerative disease: the role of amyloid-beta and tau. American Journal of Alzheimer's Disease and Other Dementias. 21: 126-30. PMID 16634469 DOI: 10.1177/153331750602100213  1
2006 Moreira PI, Zhu X, Liu Q, Honda K, Siedlak SL, Harris PL, Smith MA, Perry G. Compensatory responses induced by oxidative stress in Alzheimer disease. Biological Research. 39: 7-13. PMID 16629160 DOI: 10.4067/S0716-97602006000100002  1
2006 Lee HG, Zhu X, Perry G, Smith MA. The fallacy of amyloid and cognition in Alzheimer's disease. Drugs & Aging. 23: 179. PMID 16536639 DOI: 10.2165/00002512-200623020-00007  1
2006 Zhu X, Lee HG, Moreira PI, Smith MA, Perry G. Presenilin mutation: a deadly first hit in Alzheimer disease. A commentary on "aging sensitizes towards ROS formation and lipid peroxidation in PS1M146L transgenic mice". Free Radical Biology & Medicine. 40: 737-9. PMID 16520226 DOI: 10.1016/j.freeradbiomed.2005.12.028  1
2006 Moreira PI, Zhu X, Lee HG, Honda K, Smith MA, Perry G. The (un)balance between metabolic and oxidative abnormalities and cellular compensatory responses in Alzheimer disease. Mechanisms of Ageing and Development. 127: 501-6. PMID 16516950 DOI: 10.1016/j.mad.2006.01.024  1
2006 Casadesus G, Webber KM, Atwood CS, Pappolla MA, Perry G, Bowen RL, Smith MA. Luteinizing hormone modulates cognition and amyloid-beta deposition in Alzheimer APP transgenic mice. Biochimica Et Biophysica Acta. 1762: 447-52. PMID 16503402 DOI: 10.1016/j.bbadis.2006.01.008  1
2006 Lee HG, Zhu X, Nunomura A, Perry G, Smith MA. Amyloid beta: the alternate hypothesis. Current Alzheimer Research. 3: 75-80. PMID 16472207 DOI: 10.2174/156720506775697124  1
2006 Webber KM, Casadesus G, Zhu X, Obrenovich ME, Atwood CS, Perry G, Bowen RL, Smith MA. The cell cycle and hormonal fluxes in Alzheimer disease: a novel therapeutic target. Current Pharmaceutical Design. 12: 691-7. PMID 16472159 DOI: 10.2174/138161206775474305  1
2006 Moreira PI, Honda K, Zhu X, Nunomura A, Casadesus G, Smith MA, Perry G. Brain and brawn: parallels in oxidative strength. Neurology. 66: S97-101. PMID 16432155 DOI: 10.1212/01.wnl.0000192307.15103.83  1
2006 Castellani RJ, Zhu X, Lee HG, Perry G, Smith MA, Casadesus G. Neurogenesis in human hippocampus: Implications for Alzheimer disease pathogenesis Neuroembryology and Aging. 4: 175-182. DOI: 10.1159/000118927  1
2005 Casadesus G, Smith MA, Perry G. Commentary: "Ceramide and cholesterol: possible connections between normal aging of the brain and Alzheimer's disease. Just hypotheses or molecular pathways to be identified?" by Claudio Costantini, Rekha M.K. Kolasani, and Luigi Puglielli. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 1: 51-2. PMID 19595817 DOI: 10.1016/j.jalz.2005.06.011  1
2005 Castellani RJ, Siedlak SL, Fortino AE, Perry G, Ghetti B, Smith MA. Chitin-like polysaccharides in Alzheimer's disease brains. Current Alzheimer Research. 2: 419-23. PMID 16248847 DOI: 10.2174/156720505774330555  1
2005 Moreira PI, Honda K, Liu Q, Santos MS, Oliveira CR, Aliev G, Nunomura A, Zhu X, Smith MA, Perry G. Oxidative stress: the old enemy in Alzheimer's disease pathophysiology. Current Alzheimer Research. 2: 403-8. PMID 16248845 DOI: 10.2174/156720505774330537  1
2005 Zhu X, Mei M, Lee HG, Wang Y, Han J, Perry G, Smith MA. P38 activation mediates amyloid-beta cytotoxicity. Neurochemical Research. 30: 791-6. PMID 16187214 DOI: 10.1007/s11064-005-6872-x  1
2005 Dwyer BE, Takeda A, Zhu X, Perry G, Smith MA. Ferric cycle activity and Alzheimer disease. Current Neurovascular Research. 2: 261-7. PMID 16181119 DOI: 10.2174/1567202054368371  1
2005 Moreira PI, Oliveira CR, Santos MS, Nunomura A, Honda K, Zhu X, Smith MA, Perry G. A second look into the oxidant mechanisms in Alzheimer's disease. Current Neurovascular Research. 2: 179-84. PMID 16181112 DOI: 10.2174/1567202053586758  1
2005 Santa-María I, Hernández F, Smith MA, Perry G, Avila J, Moreno FJ. Neurotoxic dopamine quinone facilitates the assembly of tau into fibrillar polymers. Molecular and Cellular Biochemistry. 278: 203-12. PMID 16180106 DOI: 10.1007/s11010-005-7499-6  1
2005 Lin D, Lee HG, Liu Q, Perry G, Smith MA, Sayre LM. 4-Oxo-2-nonenal is both more neurotoxic and more protein reactive than 4-hydroxy-2-nonenal. Chemical Research in Toxicology. 18: 1219-31. PMID 16097795 DOI: 10.1021/tx050080q  1
2005 Petersen RB, Siedlak SL, Lee HG, Kim YS, Nunomura A, Tagliavini F, Ghetti B, Cras P, Moreira PI, Castellani RJ, Guentchev M, Budka H, Ironside JW, Gambetti P, Smith MA, ... Perry G, et al. Redox metals and oxidative abnormalities in human prion diseases. Acta Neuropathologica. 110: 232-8. PMID 16096758 DOI: 10.1007/s00401-005-1034-4  1
2005 Zhu X, Moreira PI, Smith MA, Perry G. Alzheimer's disease: an intracellular movement disorder? Trends in Molecular Medicine. 11: 391-3. PMID 16087404 DOI: 10.1016/j.molmed.2005.07.002  1
2005 Liu G, Garrett MR, Men P, Zhu X, Perry G, Smith MA. Nanoparticle and other metal chelation therapeutics in Alzheimer disease. Biochimica Et Biophysica Acta. 1741: 246-52. PMID 16051470 DOI: 10.1016/j.bbadis.2005.06.006  1
2005 Moreira PI, Smith MA, Zhu X, Nunomura A, Castellani RJ, Perry G. Oxidative stress and neurodegeneration. Annals of the New York Academy of Sciences. 1043: 545-52. PMID 16037277 DOI: 10.1196/annals.1333.062  1
2005 Webber KM, Casadesus G, Marlatt MW, Perry G, Hamlin CR, Atwood CS, Bowen RL, Smith MA. Estrogen bows to a new master: the role of gonadotropins in Alzheimer pathogenesis. Annals of the New York Academy of Sciences. 1052: 201-9. PMID 16024763 DOI: 10.1196/annals.1347.020  1
2005 Ashford JW, Atwood CS, Blass JP, Bowen RL, Finch CE, Iqbal K, Joseph JA, Perry G. What is aging? What is its role in Alzheimer's disease? What can we do about it? Journal of Alzheimer's Disease : Jad. 7: 247-53; discussion 2. PMID 16006669  1
2005 Santa-María I, Smith MA, Perry G, Hernández F, Avila J, Moreno FJ. Effect of quinones on microtubule polymerization: a link between oxidative stress and cytoskeletal alterations in Alzheimer's disease. Biochimica Et Biophysica Acta. 1740: 472-80. PMID 15949717 DOI: 10.1016/j.bbadis.2004.11.024  1
2005 Webber KM, Casadesus G, Perry G, Atwood CS, Bowen R, Smith MA. Gender differences in Alzheimer disease: the role of luteinizing hormone in disease pathogenesis. Alzheimer Disease and Associated Disorders. 19: 95-9. PMID 15942328 DOI: 10.1097/01.wad.0000165512.90864.3f  1
2005 Lee HG, Castellani RJ, Zhu X, Perry G, Smith MA. Amyloid-beta in Alzheimer's disease: the horse or the cart? Pathogenic or protective? International Journal of Experimental Pathology. 86: 133-8. PMID 15910547 DOI: 10.1111/j.0959-9673.2005.00429.x  1
2005 Sahin M, Karauzum SB, Perry G, Smith MA, Aliciguzel Y. Retinoic acid isomers protect hippocampal neurons from amyloid-beta induced neurodegeneration. Neurotoxicity Research. 7: 243-50. PMID 15897158 DOI: 10.1007/BF03036453  1
2005 Marlatt MW, Webber KM, Moreira PI, Lee HG, Casadesus G, Honda K, Zhu X, Perry G, Smith MA. Therapeutic opportunities in Alzheimer disease: one for all or all for one? Current Medicinal Chemistry. 12: 1137-47. PMID 15892629 DOI: 10.2174/0929867053764644  1
2005 Zhu X, Smith MA, Perry G, Wang Y, Ross AP, Zhao HW, Lamanna JC, Drew KL. MAPKs are differentially modulated in arctic ground squirrels during hibernation. Journal of Neuroscience Research. 80: 862-8. PMID 15884016 DOI: 10.1002/jnr.20526  1
2005 Barbeito L, Chun J, Binder LI, Neto VM, Perry G, Scazzochio C, Violini G. The end of a Chilean institute. Science (New York, N.Y.). 308: 792-3. PMID 15879193 DOI: 10.1126/science.308.5723.792b  1
2005 Reddy VP, Garrett MR, Perry G, Smith MA. Carnosine: a versatile antioxidant and antiglycating agent. Science of Aging Knowledge Environment : Sage Ke. 2005: pe12. PMID 15872311 DOI: 10.1126/sageke.2005.18.pe12  1
2005 Lee HG, Perry G, Moreira PI, Garrett MR, Liu Q, Zhu X, Takeda A, Nunomura A, Smith MA. Tau phosphorylation in Alzheimer's disease: pathogen or protector? Trends in Molecular Medicine. 11: 164-9. PMID 15823754 DOI: 10.1016/j.molmed.2005.02.008  1
2005 Honda K, Smith MA, Zhu X, Baus D, Merrick WC, Tartakoff AM, Hattier T, Harris PL, Siedlak SL, Fujioka H, Liu Q, Moreira PI, Miller FP, Nunomura A, Shimohama S, ... Perry G, et al. Ribosomal RNA in Alzheimer disease is oxidized by bound redox-active iron. The Journal of Biological Chemistry. 280: 20978-86. PMID 15767256 DOI: 10.1074/jbc.M500526200  1
2005 Moreira PI, Smith MA, Zhu X, Honda K, Lee HG, Aliev G, Perry G. Oxidative damage and Alzheimer's disease: are antioxidant therapies useful? Drug News & Perspectives. 18: 13-9. PMID 15753972 DOI: 10.1358/dnp.2005.18.1.877164  1
2005 Zhu X, Perry G, Smith MA. Insulin signaling, diabetes mellitus and risk of Alzheimer disease. Journal of Alzheimer's Disease : Jad. 7: 81-4. PMID 15750216 DOI: 10.3233/JAD-2005-7108  1
2005 Casadesus G, Atwood CS, Zhu X, Hartzler AW, Webber KM, Perry G, Bowen RL, Smith MA. Evidence for the role of gonadotropin hormones in the development of Alzheimer disease. Cellular and Molecular Life Sciences : Cmls. 62: 293-8. PMID 15723165 DOI: 10.1007/s00018-004-4384-0  1
2005 Liu Q, Smith MA, Avilá J, DeBernardis J, Kansal M, Takeda A, Zhu X, Nunomura A, Honda K, Moreira PI, Oliveira CR, Santos MS, Shimohama S, Aliev G, de la Torre J, ... ... Perry G, et al. Alzheimer-specific epitopes of tau represent lipid peroxidation-induced conformations. Free Radical Biology & Medicine. 38: 746-54. PMID 15721985 DOI: 10.1016/j.freeradbiomed.2004.11.005  1
2005 Smith MA, Nunomura A, Lee HG, Zhu X, Moreira PI, Avila J, Perry G. Chronological primacy of oxidative stress in Alzheimer disease. Neurobiology of Aging. 26: 579-80. PMID 15708430 DOI: 10.1016/j.neurobiolaging.2004.09.021  1
2005 Tamagno E, Parola M, Bardini P, Piccini A, Borghi R, Guglielmotto M, Santoro G, Davit A, Danni O, Smith MA, Perry G, Tabaton M. Beta-site APP cleaving enzyme up-regulation induced by 4-hydroxynonenal is mediated by stress-activated protein kinases pathways. Journal of Neurochemistry. 92: 628-36. PMID 15659232 DOI: 10.1111/j.1471-4159.2004.02895.x  1
2005 Webber KM, Smith MA, Lee HG, Harris PL, Moreira P, Perry G, Zhu X. Mitogen- and stress-activated protein kinase 1: convergence of the ERK and p38 pathways in Alzheimer's disease. Journal of Neuroscience Research. 79: 554-60. PMID 15635602 DOI: 10.1002/jnr.20380  1
2005 Liu Q, Lee HG, Honda K, Siedlak SL, Harris PL, Cash AD, Zhu X, Avila J, Nunomura A, Takeda A, Smith MA, Perry G. Tau modifiers as therapeutic targets for Alzheimer's disease. Biochimica Et Biophysica Acta. 1739: 211-5. PMID 15615639 DOI: 10.1016/j.bbadis.2004.06.021  1
2005 Yuan J, Kinter M, McGeehan J, Perry G, Kneale G, Gambetti P, Zou WQ. Concealment of epitope by reduction and alkylation in prion protein. Biochemical and Biophysical Research Communications. 326: 652-9. PMID 15596149 DOI: 10.1016/j.bbrc.2004.11.088  1
2005 Moreira PI, Siedlak SL, Aliev G, Zhu X, Cash AD, Smith MA, Perry G. Oxidative stress mechanisms and potential therapeutics in Alzheimer disease. Journal of Neural Transmission (Vienna, Austria : 1996). 112: 921-32. PMID 15583960 DOI: 10.1007/s00702-004-0242-8  1
2005 Honda K, Moreira PI, Liu Q, Siedlak SL, Zhu X, Smith MA, Perry G. Redox active iron at the center of oxidative stress in Alzheimer disease Letters in Drug Design and Discovery. 2: 479-482. DOI: 10.2174/1570180054771545  1
2004 Sayre LM, Harris PL, Perry G, Smith MA. In situ localization of nonenzymatic peroxidase-like activity of tissue-bound transition metals. Current Protocols in Toxicology / Editorial Board, Mahin D. Maines (Editor-in-Chief) ... [Et Al.]. Unit17.4. PMID 23045100 DOI: 10.1002/0471140856.tx1704s20  1
2004 Aliev G, Smith MA, de la Torre JC, Perry G. Mitochondria as a primary target for vascular hypoperfusion and oxidative stress in Alzheimer's disease. Mitochondrion. 4: 649-63. PMID 16120422 DOI: 10.1016/j.mito.2004.07.018  1
2004 Avila J, Pérez M, Lucas JJ, Gómez-Ramos A, Santa María I, Moreno F, Smith M, Perry G, Hernández F. Assembly in vitro of tau protein and its implications in Alzheimer's disease. Current Alzheimer Research. 1: 97-101. PMID 15975073 DOI: 10.2174/1567205043332207  1
2004 Moreira PI, Smith MA, Zhu X, Santos MS, Oliveira CR, Perry G. Therapeutic potential of oxidant mechanisms in Alzheimer's disease. Expert Review of Neurotherapeutics. 4: 995-1004. PMID 15853526 DOI: 10.1586/14737175.4.6.995  1
2004 Zhu X, Smith MA, Perry G, Aliev G. Mitochondrial failures in Alzheimer's disease. American Journal of Alzheimer's Disease and Other Dementias. 19: 345-52. PMID 15633943 DOI: 10.1177/153331750401900611  1
2004 de la Torre J, Aliev G, Perry G. Drug therapy in Alzheimer's disease. The New England Journal of Medicine. 351: 1911-3; author reply. PMID 15509830 DOI: 10.1056/NEJM200410283511822  1
2004 Lee HG, Moreira PI, Zhu X, Smith MA, Perry G. Staying connected: synapses in Alzheimer disease. The American Journal of Pathology. 165: 1461-4. PMID 15509517 DOI: 10.1016/S0002-9440(10)63404-9  1
2004 Casadesus G, Zhu X, Atwood CS, Webber KM, Perry G, Bowen RL, Smith MA. Beyond estrogen: targeting gonadotropin hormones in the treatment of Alzheimer's disease. Current Drug Targets. Cns and Neurological Disorders. 3: 281-5. PMID 15379604 DOI: 10.2174/1568007043337265  1
2004 Nunomura A, Chiba S, Lippa CF, Cras P, Kalaria RN, Takeda A, Honda K, Smith MA, Perry G. Neuronal RNA oxidation is a prominent feature of familial Alzheimer's disease. Neurobiology of Disease. 17: 108-13. PMID 15350971 DOI: 10.1016/j.nbd.2004.06.003  1
2004 Takeda A, Itoyama Y, Kimpara T, Zhu X, Avila J, Dwyer BE, Perry G, Smith MA. Heme catabolism and heme oxygenase in neurodegenerative disease. Antioxidants & Redox Signaling. 6: 888-94. PMID 15345149 DOI: 10.1089/ars.2004.6.888  1
2004 Zhu X, Webber KM, Casadesus G, Raina AK, Lee HG, Marlatt M, Hartzler A, Atwood CS, Perry G, Smith MA. Mitotic and gender parallels in Alzheimer disease: therapeutic opportunities. Current Drug Targets. 5: 559-63. PMID 15270202 DOI: 10.2174/1389450043345317  1
2004 Aliyev A, Seyidova D, Rzayev N, Obrenovich ME, Lamb BT, Chen SG, Smith MA, Perry G, de la Torre JC, Aliev G. Is nitric oxide a key target in the pathogenesis of brain lesions during the development of Alzheimer's disease? Neurological Research. 26: 547-53. PMID 15265272 DOI: 10.1179/01610425017613  1
2004 Lee HG, Casadesus G, Zhu X, Takeda A, Perry G, Smith MA. Challenging the amyloid cascade hypothesis: senile plaques and amyloid-beta as protective adaptations to Alzheimer disease. Annals of the New York Academy of Sciences. 1019: 1-4. PMID 15246983 DOI: 10.1196/annals.1297.001  1
2004 Castellani RJ, Smith MA, Perry G, Friedland RP. Cerebral amyloid angiopathy: major contributor or decorative response to Alzheimer's disease pathogenesis. Neurobiology of Aging. 25: 599-602; discussion . PMID 15172735 DOI: 10.1016/j.neurobiolaging.2003.12.019  1
2004 Zhu X, Wang Y, Ogawa O, Lee HG, Raina AK, Siedlak SL, Harris PL, Fujioka H, Shimohama S, Tabaton M, Atwood CS, Petersen RB, Perry G, Smith MA. Neuroprotective properties of Bcl-w in Alzheimer disease. Journal of Neurochemistry. 89: 1233-40. PMID 15147516 DOI: 10.1111/j.1471-4159.2004.02416.x  1
2004 Dozza B, Smith MA, Perry G, Tabaton M, Strocchi P. Regulation of glycogen synthase kinase-3beta by products of lipid peroxidation in human neuroblastoma cells. Journal of Neurochemistry. 89: 1224-32. PMID 15147515 DOI: 10.1111/j.1471-4159.2004.02413.x  1
2004 Dwyer BE, Raina AK, Perry G, Smith MA. Homocysteine and Alzheimer's disease: a modifiable risk? Free Radical Biology & Medicine. 36: 1471-5. PMID 15135184 DOI: 10.1016/j.freeradbiomed.2004.03.009  1
2004 Honda K, Casadesus G, Petersen RB, Perry G, Smith MA. Oxidative stress and redox-active iron in Alzheimer's disease. Annals of the New York Academy of Sciences. 1012: 179-82. PMID 15105265 DOI: 10.1196/annals.1306.015  1
2004 Casadesus G, Smith MA, Zhu X, Aliev G, Cash AD, Honda K, Petersen RB, Perry G. Alzheimer disease: evidence for a central pathogenic role of iron-mediated reactive oxygen species. Journal of Alzheimer's Disease : Jad. 6: 165-9. PMID 15096700 DOI: 10.3233/JAD-2004-6208  1
2004 Lee HG, Casadesus G, Zhu X, Joseph JA, Perry G, Smith MA. Perspectives on the amyloid-beta cascade hypothesis. Journal of Alzheimer's Disease : Jad. 6: 137-45. PMID 15096697 DOI: 10.3233/JAD-2004-6205  1
2004 Kang SC, Brown DR, Whiteman M, Li R, Pan T, Perry G, Wisniewski T, Sy MS, Wong BS. Prion protein is ubiquitinated after developing protease resistance in the brains of scrapie-infected mice. The Journal of Pathology. 203: 603-8. PMID 15095484 DOI: 10.1002/path.1555  1
2004 Zhu X, Raina AK, Lee HG, Casadesus G, Smith MA, Perry G. Oxidative stress signalling in Alzheimer's disease. Brain Research. 1000: 32-9. PMID 15053949 DOI: 10.1016/j.brainres.2004.01.012  1
2004 Zhu X, Raina AK, Perry G, Smith MA. Alzheimer's disease: the two-hit hypothesis. The Lancet. Neurology. 3: 219-26. PMID 15039034 DOI: 10.1016/S1474-4422(04)00707-0  1
2004 Zhu X, McShea A, Harris PL, Raina AK, Castellani RJ, Funk JO, Shah S, Atwood C, Bowen R, Bowser R, Morelli L, Perry G, Smith MA. Elevated expression of a regulator of the G2/M phase of the cell cycle, neuronal CIP-1-associated regulator of cyclin B, in Alzheimer's disease. Journal of Neuroscience Research. 75: 698-703. PMID 14991845 DOI: 10.1002/jnr.20028  1
2004 Ghanbari HA, Ghanbari K, Harris PL, Jones PK, Kubat Z, Castellani RJ, Wolozin BL, Smith MA, Perry G. Oxidative damage in cultured human olfactory neurons from Alzheimer's disease patients. Aging Cell. 3: 41-4. PMID 14965355 DOI: 10.1111/j.1474-9728.2004.00083.x  1
2004 Lee HG, Ogawa O, Zhu X, O'Neill MJ, Petersen RB, Castellani RJ, Ghanbari H, Perry G, Smith MA. Aberrant expression of metabotropic glutamate receptor 2 in the vulnerable neurons of Alzheimer's disease. Acta Neuropathologica. 107: 365-71. PMID 14872255 DOI: 10.1007/s00401-004-0820-8  1
2004 Bowen RL, Verdile G, Liu T, Parlow AF, Perry G, Smith MA, Martins RN, Atwood CS. Luteinizing hormone, a reproductive regulator that modulates the processing of amyloid-beta precursor protein and amyloid-beta deposition. The Journal of Biological Chemistry. 279: 20539-45. PMID 14871891 DOI: 10.1074/jbc.M311993200  1
2004 Liu T, Perry G, Chan HW, Verdile G, Martins RN, Smith MA, Atwood CS. Amyloid-beta-induced toxicity of primary neurons is dependent upon differentiation-associated increases in tau and cyclin-dependent kinase 5 expression. Journal of Neurochemistry. 88: 554-63. PMID 14720205 DOI: 10.1046/j.1471-4159.2003.02196.x  1
2004 Atwood CS, Perry G, Zeng H, Kato Y, Jones WD, Ling KQ, Huang X, Moir RD, Wang D, Sayre LM, Smith MA, Chen SG, Bush AI. Copper mediates dityrosine cross-linking of Alzheimer's amyloid-beta. Biochemistry. 43: 560-8. PMID 14717612 DOI: 10.1021/bi0358824  1
2004 Zhu X, Perry G, Smith MA. Amyotrophic lateral sclerosis: a novel hypothesis involving a gained 'loss of function' in the JNK/SAPK pathway. Redox Report : Communications in Free Radical Research. 8: 129-33. PMID 12935309 DOI: 10.1179/135100003225001494  0.4
2004 Bowen R, Atwood CS, Perry G, Smith MA. Mechanisms Involved in Gender Differences in Alzheimer's Disease: The Role of Leuteinizing and Follicle Stimulating Hormones Principles of Gender-Specific Medicine. 2: 1234-1237. DOI: 10.1016/B978-012440905-7/50388-1  1
2003 Raina AK, Zhu X, Shimohama S, Perry G, Smith MA. Tipping the apoptotic balance in Alzheimer's disease: the abortosis concept. Cell Biochemistry and Biophysics. 39: 249-55. PMID 14716079 DOI: 10.1385/CBB:39:3:249  1
2003 Aliev G, Smith MA, Obrenovich ME, de la Torre JC, Perry G. Role of vascular hypoperfusion-induced oxidative stress and mitochondria failure in the pathogenesis of Azheimer disease. Neurotoxicity Research. 5: 491-504. PMID 14715433 DOI: 10.1007/BF03033159  1
2003 Lee HG, Petersen RB, Zhu X, Honda K, Aliev G, Smith MA, Perry G. Will preventing protein aggregates live up to its promise as prophylaxis against neurodegenerative diseases? Brain Pathology (Zurich, Switzerland). 13: 630-8. PMID 14655766 DOI: 10.1111/j.1750-3639.2003.tb00491.x  1
2003 Zhu X, Raina AK, Lee HG, Chao M, Nunomura A, Tabaton M, Petersen RB, Perry G, Smith MA. Oxidative stress and neuronal adaptation in Alzheimer disease: the role of SAPK pathways. Antioxidants & Redox Signaling. 5: 571-6. PMID 14580312 DOI: 10.1089/152308603770310220  1
2003 Perry G, Nunomura A, Raina AK, Aliev G, Siedlak SL, Harris PL, Casadesus G, Petersen RB, Bligh-Glover W, Balraj E, Petot GJ, Smith MA. A metabolic basis for Alzheimer disease. Neurochemical Research. 28: 1549-52. PMID 14570400 DOI: 10.1023/A:1025678510480  1
2003 Aliev G, Seyidova D, Lamb BT, Obrenovich ME, Siedlak SL, Vinters HV, Friedland RP, LaManna JC, Smith MA, Perry G. Mitochondria and vascular lesions as a central target for the development of Alzheimer's disease and Alzheimer disease-like pathology in transgenic mice. Neurological Research. 25: 665-74. PMID 14503022 DOI: 10.1179/016164103101201977  1
2003 Atwood CS, Bowen RL, Smith MA, Perry G. Cerebrovascular requirement for sealant, anti-coagulant and remodeling molecules that allow for the maintenance of vascular integrity and blood supply. Brain Research. Brain Research Reviews. 43: 164-78. PMID 14499467 DOI: 10.1016/S0165-0173(03)00206-6  1
2003 Aliev G, Obrenovich ME, Smith MA, Perry G. Hypoperfusion, Mitochondria Failure, Oxidative Stress, and Alzheimer Disease. Journal of Biomedicine & Biotechnology. 2003: 162-163. PMID 12975531 DOI: 10.1155/S1110724303305029  1
2003 Perry G, Castellani RJ, Smith MA, Harris PL, Kubat Z, Ghanbari K, Jones PK, Cordone G, Tabaton M, Wolozin B, Ghanbari H. Oxidative damage in the olfactory system in Alzheimer's disease. Acta Neuropathologica. 106: 552-6. PMID 12955399 DOI: 10.1007/s00401-003-0761-7  1
2003 Liu Q, Raina AK, Smith MA, Sayre LM, Perry G. Hydroxynonenal, toxic carbonyls, and Alzheimer disease. Molecular Aspects of Medicine. 24: 305-13. PMID 12893008 DOI: 10.1016/S0098-2997(03)00025-6  1
2003 Ogawa O, Lee HG, Zhu X, Raina A, Harris PL, Castellani RJ, Perry G, Smith MA. Increased p27, an essential component of cell cycle control, in Alzheimer's disease. Aging Cell. 2: 105-10. PMID 12882323  1
2003 Zhu X, Sun Z, Lee HG, Siedlak SL, Perry G, Smith MA. Distribution, levels, and activation of MEK1 in Alzheimer's disease. Journal of Neurochemistry. 86: 136-42. PMID 12807433 DOI: 10.1046/j.1471-4159.2003.01820.x  1
2003 Matsubara E, Bryant-Thomas T, Pacheco Quinto J, Henry TL, Poeggeler B, Herbert D, Cruz-Sanchez F, Chyan YJ, Smith MA, Perry G, Shoji M, Abe K, Leone A, Grundke-Ikbal I, Wilson GL, et al. Melatonin increases survival and inhibits oxidative and amyloid pathology in a transgenic model of Alzheimer's disease. Journal of Neurochemistry. 85: 1101-8. PMID 12753069 DOI: 10.1046/j.1471-4159.2003.01654.x  1
2003 Tateyama M, Takeda A, Onodera Y, Matsuzaki M, Hasegawa T, Nunomura A, Hirai K, Perry G, Smith MA, Itoyama Y. Oxidative stress and predominant Abeta42(43) deposition in myopathies with rimmed vacuoles. Acta Neuropathologica. 105: 581-5. PMID 12734664 DOI: 10.1007/s00401-003-0685-2  1
2003 Bruckner SR, Perry G, Estus S. 4-hydroxynonenal contributes to NGF withdrawal-induced neuronal apoptosis. Journal of Neurochemistry. 85: 999-1005. PMID 12716431  1
2003 Bianco NR, Perry G, Smith MA, Templeton DJ, Montano MM. Functional implications of antiestrogen induction of quinone reductase: inhibition of estrogen-induced deoxyribonucleic acid damage. Molecular Endocrinology (Baltimore, Md.). 17: 1344-55. PMID 12714703 DOI: 10.1210/me.2002-0382  1
2003 Cash AD, Aliev G, Siedlak SL, Nunomura A, Fujioka H, Zhu X, Raina AK, Vinters HV, Tabaton M, Johnson AB, Paula-Barbosa M, Avíla J, Jones PK, Castellani RJ, Smith MA, ... Perry G, et al. Microtubule reduction in Alzheimer's disease and aging is independent of tau filament formation. The American Journal of Pathology. 162: 1623-7. PMID 12707046  1
2003 Veurink G, Liu D, Taddei K, Perry G, Smith MA, Robertson TA, Hone E, Groth DM, Atwood CS, Martins RN. Reduction of inclusion body pathology in ApoE-deficient mice fed a combination of antioxidants. Free Radical Biology & Medicine. 34: 1070-7. PMID 12684092 DOI: 10.1016/S0891-5849(03)00042-X  1
2003 Ogawa O, Zhu X, Lee HG, Raina A, Obrenovich ME, Bowser R, Ghanbari HA, Castellani RJ, Perry G, Smith MA. Ectopic localization of phosphorylated histone H3 in Alzheimer's disease: a mitotic catastrophe? Acta Neuropathologica. 105: 524-8. PMID 12677454 DOI: 10.1007/s00401-003-0684-3  1
2003 Zhu X, Ogawa O, Wang Y, Perry G, Smith MA. JKK1, an upstream activator of JNK/SAPK, is activated in Alzheimer's disease. Journal of Neurochemistry. 85: 87-93. PMID 12641730 DOI: 10.1046/j.1471-4159.2003.01645.x  0.4
2003 Dong J, Atwood CS, Anderson VE, Siedlak SL, Smith MA, Perry G, Carey PR. Metal binding and oxidation of amyloid-beta within isolated senile plaque cores: Raman microscopic evidence. Biochemistry. 42: 2768-73. PMID 12627941 DOI: 10.1021/bi0272151  1
2003 Smith MA, Perry G, Atwood CS, Bowen RL. Estrogen replacement and risk of Alzheimer disease. Jama. 289: 1100; author reply 1. PMID 12622570 DOI: 10.1001/jama.289.9.1100-a  1
2003 Atwood CS, Perry G, Smith MA. Cerebral hemorrhage and amyloid-beta. Science (New York, N.Y.). 299: 1014; author reply 1. PMID 12586924 DOI: 10.1126/science.299.5609.1014a  1
2003 Perry G, Taddeo MA, Petersen RB, Castellani RJ, Harris PL, Siedlak SL, Cash AD, Liu Q, Nunomura A, Atwood CS, Smith MA. Adventiously-bound redox active iron and copper are at the center of oxidative damage in Alzheimer disease. Biometals : An International Journal On the Role of Metal Ions in Biology, Biochemistry, and Medicine. 16: 77-81. PMID 12572666 DOI: 10.1023/A:1020731021276  1
2002 Ogawa O, Zhu X, Perry G, Smith MA. Mitochondrial abnormalities and oxidative imbalance in neurodegenerative disease. Science of Aging Knowledge Environment : Sage Ke. 2002: pe16. PMID 14603007 DOI: 10.1126/SAGEKE.2002.41.PE16  0.44
2002 Reddy VP, Obrenovich ME, Atwood CS, Perry G, Smith MA. Involvement of Maillard reactions in Alzheimer disease. Neurotoxicity Research. 4: 191-209. PMID 12829400 DOI: 10.1080/1029840290007321  1
2002 Lee HG, Zhu X, Ghanbari HA, Ogawa O, Raina AK, O'Neill MJ, Perry G, Smith MA. Differential regulation of glutamate receptors in Alzheimer's disease. Neuro-Signals. 11: 282-92. PMID 12566929 DOI: 10.1159/000067427  1
2002 Zhu X, Lee HG, Raina AK, Perry G, Smith MA. The role of mitogen-activated protein kinase pathways in Alzheimer's disease. Neuro-Signals. 11: 270-81. PMID 12566928 DOI: 10.1159/000067426  1
2002 Perry G, Cash AD, Smith MA. Alzheimer Disease and Oxidative Stress. Journal of Biomedicine & Biotechnology. 2: 120-123. PMID 12488575 DOI: 10.1155/S1110724302203010  1
2002 Takata K, Kitamura Y, Kakimura J, Shibagaki K, Taniguchi T, Gebicke-Haerter PJ, Smith MA, Perry G, Shimohama S. Possible protective mechanisms of heme oxygenase-1 in the brain. Annals of the New York Academy of Sciences. 977: 501-6. PMID 12480792 DOI: 10.1111/j.1749-6632.2002.tb04857.x  1
2002 Kakimura J, Kitamura Y, Takata K, Tsuchiya D, Taniguchi T, Gebicke-Haerter PJ, Smith MA, Perry G, Shimohama S. Possible involvement of ER chaperone Grp78 on reduced formation of amyloid-beta deposits. Annals of the New York Academy of Sciences. 977: 327-32. PMID 12480769 DOI: 10.1111/j.1749-6632.2002.tb04834.x  1
2002 Aliev G, Seyidova D, Neal ML, Shi J, Lamb BT, Siedlak SL, Vinters HV, Head E, Perry G, Lamanna JC, Friedland RP, Cotman CW. Atherosclerotic lesions and mitochondria DNA deletions in brain microvessels as a central target for the development of human AD and AD-like pathology in aged transgenic mice. Annals of the New York Academy of Sciences. 977: 45-64. PMID 12480733  1
2002 Obrenovich ME, Joseph JA, Atwood CS, Perry G, Smith MA. Amyloid-beta: a (life) preserver for the brain. Neurobiology of Aging. 23: 1097-9. PMID 12470809 DOI: 10.1016/S0197-4580(02)00038-6  1
2002 Perry G, Taddeo MA, Nunomura A, Zhu X, Zenteno-Savin T, Drew KL, Shimohama S, Avila J, Castellani RJ, Smith MA. Comparative biology and pathology of oxidative stress in Alzheimer and other neurodegenerative diseases: beyond damage and response. Comparative Biochemistry and Physiology. Toxicology & Pharmacology : Cbp. 133: 507-13. PMID 12458179 DOI: 10.1016/S1532-0456(02)00119-9  1
2002 Drew KL, Tøien Ø, Rivera PM, Smith MA, Perry G, Rice ME. Role of the antioxidant ascorbate in hibernation and warming from hibernation. Comparative Biochemistry and Physiology. Toxicology & Pharmacology : Cbp. 133: 483-92. PMID 12458177 DOI: 10.1016/S1532-0456(02)00118-7  1
2002 Perry G, Nunomura A, Cash AD, Taddeo MA, Hirai K, Aliev G, Avila J, Wataya T, Shimohama S, Atwood CS, Smith MA. Reactive oxygen: its sources and significance in Alzheimer disease. Journal of Neural Transmission. Supplementum. 69-75. PMID 12456052 DOI: 10.1007/978-3-7091-6139-5_7  1
2002 Perry G, Nunomura A, Hirai K, Zhu X, Pérez M, Avila J, Castellani RJ, Atwood CS, Aliev G, Sayre LM, Takeda A, Smith MA. Is oxidative damage the fundamental pathogenic mechanism of Alzheimer's and other neurodegenerative diseases? Free Radical Biology & Medicine. 33: 1475-9. PMID 12446204 DOI: 10.1016/S0891-5849(02)01113-9  1
2002 Nunomura A, Chiba S, Kosaka K, Takeda A, Castellani RJ, Smith MA, Perry G. Neuronal RNA oxidation is a prominent feature of dementia with Lewy bodies. Neuroreport. 13: 2035-9. PMID 12438921 DOI: 10.1097/00001756-200211150-00009  1
2002 Bishop GM, Robinson SR, Liu Q, Perry G, Atwood CS, Smith MA. Iron: a pathological mediator of Alzheimer disease? Developmental Neuroscience. 24: 184-7. PMID 12401957 DOI: 10.1159/000065696  1
2002 Smith MA, Casadesus G, Joseph JA, Perry G. Amyloid-beta and tau serve antioxidant functions in the aging and Alzheimer brain. Free Radical Biology & Medicine. 33: 1194-9. PMID 12398927 DOI: 10.1016/S0891-5849(02)01021-3  1
2002 Bowen RL, Smith MA, Harris PL, Kubat Z, Martins RN, Castellani RJ, Perry G, Atwood CS. Elevated luteinizing hormone expression colocalizes with neurons vulnerable to Alzheimer's disease pathology. Journal of Neuroscience Research. 70: 514-8. PMID 12391612 DOI: 10.1002/jnr.10452  1
2002 Castellani R, Hirai K, Aliev G, Drew KL, Nunomura A, Takeda A, Cash AD, Obrenovich ME, Perry G, Smith MA. Role of mitochondrial dysfunction in Alzheimer's disease. Journal of Neuroscience Research. 70: 357-60. PMID 12391597 DOI: 10.1002/jnr.10389  1
2002 Atwood CS, Bishop GM, Perry G, Smith MA. Amyloid-beta: a vascular sealant that protects against hemorrhage? Journal of Neuroscience Research. 70: 356. PMID 12391596 DOI: 10.1002/jnr.10388  1
2002 Cash AD, Perry G, Ogawa O, Raina AK, Zhu X, Smith MA. Is Alzheimer's disease a mitochondrial disorder? The Neuroscientist : a Review Journal Bringing Neurobiology, Neurology and Psychiatry. 8: 489-96. PMID 12374431 DOI: 10.1177/107385802236968  1
2002 Cash AD, Perry G, Smith MA. Therapeutic potential in Alzheimer disease. Current Medicinal Chemistry. 9: 1605-10. PMID 12171555 DOI: 10.2174/0929867023369411  1
2002 Atwood CS, Martins RN, Smith MA, Perry G. Senile plaque composition and posttranslational modification of amyloid-beta peptide and associated proteins. Peptides. 23: 1343-50. PMID 12128091 DOI: 10.1016/S0196-9781(02)00070-0  1
2002 Smith MA, Atwood CS, Joseph JA, Perry G. Ill-fated amyloid-beta vaccine. Journal of Neuroscience Research. 69: 285. PMID 12125069 DOI: 10.1002/jnr.10316  1
2002 Pappolla MA, Smith MA, Bryant-Thomas T, Bazan N, Petanceska S, Perry G, Thal LJ, Sano M, Refolo LM. Cholesterol, oxidative stress, and Alzheimer's disease: expanding the horizons of pathogenesis. Free Radical Biology & Medicine. 33: 173-81. PMID 12106813 DOI: 10.1016/S0891-5849(02)00841-9  1
2002 Pappolla MA, Simovich MJ, Bryant-Thomas T, Chyan YJ, Poeggeler B, Dubocovich M, Bick R, Perry G, Cruz-Sanchez F, Smith MA. The neuroprotective activities of melatonin against the Alzheimer beta-protein are not mediated by melatonin membrane receptors. Journal of Pineal Research. 32: 135-42. PMID 12074096 DOI: 10.1034/j.1600-079x.2002.1o838.x  1
2002 Smith MA, Joseph JA, Atwood CS, Perry G. Dangers of the amyloid-beta vaccination. Acta Neuropathologica. 104: 110. PMID 12070672 DOI: 10.1007/s00401-002-0572-2  1
2002 Smith MA, Atwood CS, Joseph JA, Perry G. Predicting the failure of amyloid-beta vaccine. Lancet. 359: 1864-5. PMID 12044411 DOI: 10.1016/S0140-6736(02)08695-6  1
2002 Zhang J, Montine TJ, Smith MA, Siedlak SL, Gu G, Robertson D, Perry G. The mitochondrial common deletion in Parkinson's disease and related movement disorders. Parkinsonism & Related Disorders. 8: 165-70. PMID 12039426 DOI: 10.1016/S1353-8020(01)00041-4  1
2002 Smith MA, Perry G, Pryor WA. Causes and consequences of oxidative stress in Alzheimer's disease. Free Radical Biology & Medicine. 32: 1049. PMID 12031888 DOI: 10.1016/S0891-5849(02)00793-1  1
2002 Clapp-Lilly KL, Smith MA, Perry G, Harris PL, Zhu X, Drew KL, Duffy LK. Melatonin exhibits antioxidant properties in a mouse brain slice model of excitotoxicity. International Journal of Circumpolar Health. 61: 32-40. PMID 12002945  1
2002 Perry G, Sayre LM, Atwood CS, Castellani RJ, Cash AD, Rottkamp CA, Smith MA. The role of iron and copper in the aetiology of neurodegenerative disorders: therapeutic implications. Cns Drugs. 16: 339-52. PMID 11994023 DOI: 10.2165/00023210-200216050-00006  1
2002 Bishop GM, Robinson SR, Smith MA, Perry G, Atwood CS. Call for Elan to publish Alzheimer's trial details. Nature. 416: 677. PMID 11961526 DOI: 10.1038/416677d  1
2002 Kakimura J, Kitamura Y, Takata K, Umeki M, Suzuki S, Shibagaki K, Taniguchi T, Nomura Y, Gebicke-Haerter PJ, Smith MA, Perry G, Shimohama S. Microglial activation and amyloid-beta clearance induced by exogenous heat-shock proteins. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 16: 601-3. PMID 11919167 DOI: 10.1096/fj.01-0530fje  1
2002 Ogawa O, Perry G, Smith MA. The "Down's" side of mitochondria. Developmental Cell. 2: 255-6. PMID 11879629 DOI: 10.1016/S1534-5807(02)00139-9  0.44
2002 Borghi R, Giliberto L, Assini A, Delacourte A, Perry G, Smith MA, Strocchi P, Zaccheo D, Tabaton M. Increase of cdk5 is related to neurofibrillary pathology in progressive supranuclear palsy. Neurology. 58: 589-92. PMID 11865137 DOI: 10.1212/WNL.58.4.589  1
2002 Smith MA, Drew KL, Nunomura A, Takeda A, Hirai K, Zhu X, Atwood CS, Raina AK, Rottkamp CA, Sayre LM, Friedland RP, Perry G. Amyloid-beta, tau alterations and mitochondrial dysfunction in Alzheimer disease: the chickens or the eggs? Neurochemistry International. 40: 527-31. PMID 11850109 DOI: 10.1016/S0197-0186(01)00123-1  1
2002 Castellani RJ, Perry G, Siedlak SL, Nunomura A, Shimohama S, Zhang J, Montine T, Sayre LM, Smith MA. Hydroxynonenal adducts indicate a role for lipid peroxidation in neocortical and brainstem Lewy bodies in humans. Neuroscience Letters. 319: 25-8. PMID 11814645 DOI: 10.1016/S0304-3940(01)02514-9  1
2002 Aliev G, Smith MA, Seyidov D, Neal ML, Lamb BT, Nunomura A, Gasimov EK, Vinters HV, Perry G, LaManna JC, Friedland RP. The role of oxidative stress in the pathophysiology of cerebrovascular lesions in Alzheimer's disease. Brain Pathology (Zurich, Switzerland). 12: 21-35. PMID 11770899  1
2002 Wataya T, Nunomura A, Smith MA, Siedlak SL, Harris PL, Shimohama S, Szweda LI, Kaminski MA, Avila J, Price DL, Cleveland DW, Sayre LM, Perry G. High molecular weight neurofilament proteins are physiological substrates of adduction by the lipid peroxidation product hydroxynonenal. The Journal of Biological Chemistry. 277: 4644-8. PMID 11733539 DOI: 10.1074/jbc.M110913200  1
2002 Perry G, Cash AD, Srinivas R, Smith MA. Metals and oxidative homeostasis in Alzheimer's disease Drug Development Research. 56: 293-299. DOI: 10.1002/ddr.10099  1
2001 Zhou F, Smith MA, Castellani RJ, Stimmelmayr R, Perry G, Drew KL, Zhu X. Hibernation, a Model of Neuroprotection. Thescientificworldjournal. 1: 108. PMID 30147589 DOI: 10.1100/tsw.2001.132  1
2001 Zhu X, Rottkamp CA, Hartzler A, Sun Z, Takeda A, Boux H, Shimohama S, Perry G, Smith MA. Activation of MKK6, an upstream activator of p38, in Alzheimer's disease. Journal of Neurochemistry. 79: 311-8. PMID 11677259 DOI: 10.1046/j.1471-4159.2001.00597.x  1
2001 Nunomura A, Perry G, Aliev G, Hirai K, Takeda A, Balraj EK, Jones PK, Ghanbari H, Wataya T, Shimohama S, Chiba S, Atwood CS, Petersen RB, Smith MA. Oxidative damage is the earliest event in Alzheimer disease. Journal of Neuropathology and Experimental Neurology. 60: 759-67. PMID 11487050 DOI: 10.1093/JNEN/60.8.759  1
2001 Campbell A, Smith MA, Sayre LM, Bondy SC, Perry G. Mechanisms by which metals promote events connected to neurodegenerative diseases. Brain Research Bulletin. 55: 125-32. PMID 11470308 DOI: 10.1016/S0361-9230(01)00455-5  1
2001 Pappolla MA, Omar RA, Chyan YJ, Ghiso J, Hsiao K, Bozner P, Perry G, Smith MA, Cruz-Sanchez F. Induction of NADPH cytochrome P450 reductase by the Alzheimer beta-protein. Amyloid as a "foreign body". Journal of Neurochemistry. 78: 121-8. PMID 11432979 DOI: 10.1046/j.1471-4159.2001.00379.x  1
2001 Sayre LM, Smith MA, Perry G. Chemistry and biochemistry of oxidative stress in neurodegenerative disease. Current Medicinal Chemistry. 8: 721-38. PMID 11375746 DOI: 10.2174/0929867013372922  1
2001 Raina AK, Hochman A, Zhu X, Rottkamp CA, Nunomura A, Siedlak SL, Boux H, Castellani RJ, Perry G, Smith MA. Abortive apoptosis in Alzheimer's disease. Acta Neuropathologica. 101: 305-10. PMID 11355301  1
2001 Clapp-Lilly KL, Smith MA, Perry G, Harris PL, Zhu X, Duffy LK. Melatonin acts as antioxidant and pro-oxidant in an organotypic slice culture model of Alzheimer's disease. Neuroreport. 12: 1277-80. PMID 11338206  1
2001 Alicigüzel Y, Ozdem SN, Ozdem SS, Karayalçin U, Siedlak SL, Perry G, Smith MA. Erythrocyte, plasma, and serum antioxidant activities in untreated toxic multinodular goiter patients. Free Radical Biology & Medicine. 30: 665-70. PMID 11295364 DOI: 10.1016/S0891-5849(00)00509-8  1
2001 Wong BS, Liu T, Li R, Pan T, Petersen RB, Smith MA, Gambetti P, Perry G, Manson JC, Brown DR, Sy MS. Increased levels of oxidative stress markers detected in the brains of mice devoid of prion protein. Journal of Neurochemistry. 76: 565-72. PMID 11208919 DOI: 10.1046/j.1471-4159.2001.00028.x  1
2001 Zhu X, Raina AK, Rottkamp CA, Aliev G, Perry G, Boux H, Smith MA. Activation and redistribution of c-jun N-terminal kinase/stress activated protein kinase in degenerating neurons in Alzheimer's disease. Journal of Neurochemistry. 76: 435-41. PMID 11208906 DOI: 10.1046/j.1471-4159.2001.00046.x  1
2001 Perry G, Zhu X, Smith MA. Do neurons have a choice in death? The American Journal of Pathology. 158: 1-2. PMID 11141471 DOI: 10.1016/S0002-9440(10)63936-3  0.64
2001 Josepha JA, Perry G, Shukitt-Hale B, Denisova NA, Martin A, Smith MA. A diet at amyloid beta? Neurobiology of Aging. 22: 161-163. DOI: 10.1016/S0197-4580(00)00206-2  1
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