Huijuan Zhang, Ph.D.

Affiliations: 
2002 University of North Carolina, Chapel Hill, Chapel Hill, NC 
Area:
Analytical Separations, Capillary Electrophoresis, Capillary Liquid Chromatography
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"Huijuan Zhang"
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SNBCP

Parents

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James W. Jorgenson grad student 2002 UNC Chapel Hill
 (Two -dimensional liquid chromatography - capillary electrophoresis and its applications.)
Binghe Wang research scientist 1997 NCSU
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Publications

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Wang B, Shan D, Wang W, et al. (2012) Synthesis of coumarin-based, esterase-sensitive cyclic prodrugs of opioid peptides with enhanced membrane permeability and enzymatic stability. Methods in Molecular Medicine. 23: 71-85
Wang W, Camenisch G, Sane DC, et al. (2000) A coumarin-based prodrug strategy to improve the oral absorption of RGD peptidomimetics. Journal of Controlled Release : Official Journal of the Controlled Release Society. 65: 245-51
Wang B, Nimkar K, Wang W, et al. (1999) Synthesis and evaluation of the physicochemical properties of esterase- sensitive cyclic prodrugs of opioid peptides using coumarinic acid and phenylpropionic acid linkers Journal of Peptide Research. 53: 370-382
Wang B, Wang W, Camenisch GP, et al. (1999) Synthesis and evaluation of novel coumarin-based esterase-sensitive cyclic prodrugs of peptidomimetic RGD analogs with improved membrane permeability. Chemical & Pharmaceutical Bulletin. 47: 90-5
Gudmundsson OS, Pauletti GM, Wang W, et al. (1999) Coumarinic acid-based cyclic prodrugs of opioid peptides that exhibit metabolic stability to peptidases and excellent cellular permeability Pharmaceutical Research. 16: 7-15
Zheng A, Wang W, Zhang H, et al. (1999) Two new improved approaches to the synthesis of coumarin-based prodrugs Tetrahedron. 55: 4237-4254
Wang B, Zhang H, Zheng A, et al. (1998) Coumarin-based prodrugs. Part 3: Structural effects on the release kinetics of esterase-sensitive prodrugs of amines. Bioorganic & Medicinal Chemistry. 6: 417-26
Wang B, Wang W, Zhang H, et al. (1996) Coumarin-based prodrugs 2. Synthesis and bioreversibility studies of an esterase-sensitive cyclic prodrug of dadle, an opioid peptide Bioorganic & Medicinal Chemistry Letters. 6: 2823-2826
Wang B, Zhang H, Wang W. (1996) Chemical feasibility studies of a potential coumarin-based prodrug system Bioorganic & Medicinal Chemistry Letters. 6: 945-950
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