Cara L. Sherwood, Ph.D.

Affiliations: 
2011 Cell Biology & Anatomy University of Arizona, Tucson, AZ 
Area:
Cell Biology, Toxicology, Immunology
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"Cara Sherwood"

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Scott Boitano grad student 2011 University of Arizona
 (Arsenic alters key components of innate immune defense in airway epithelial cells.)
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Sherwood CL, Boitano S. (2016) Airway epithelial cell exposure to distinct e-cigarette liquid flavorings reveals toxicity thresholds and activation of CFTR by the chocolate flavoring 2,5-dimethypyrazine. Respiratory Research. 17: 57
Boitano S, Hoffman J, Flynn AN, et al. (2015) The novel PAR2 ligand C391 blocks multiple PAR2 signaling pathways in vitro and in vivo. British Journal of Pharmacology
Sherwood CL, Daines MO, Price TJ, et al. (2014) A highly potent agonist to protease-activated receptor-2 reveals apical activation of the airway epithelium resulting in Ca2+-regulated ion conductance. American Journal of Physiology. Cell Physiology. 307: C718-26
Boitano S, Hoffman J, Tillu DV, et al. (2014) Development and evaluation of small peptidomimetic ligands to protease-activated receptor-2 (PAR2) through the use of lipid tethering. Plos One. 9: e99140
Sherwood CL, Liguori AE, Olsen CE, et al. (2013) Arsenic compromises conducting airway epithelial barrier properties in primary mouse and immortalized human cell cultures. Plos One. 8: e82970
Flynn AN, Hoffman J, Tillu DV, et al. (2013) Development of highly potent protease-activated receptor 2 agonists via synthetic lipid tethering. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 27: 1498-510
Sherwood CL, Lantz RC, Boitano S. (2013) Chronic arsenic exposure in nanomolar concentrations compromises wound response and intercellular signaling in airway epithelial cells. Toxicological Sciences : An Official Journal of the Society of Toxicology. 132: 222-34
Sherwood CL, Lantz RC, Burgess JL, et al. (2011) Arsenic alters ATP-dependent Ca²+ signaling in human airway epithelial cell wound response. Toxicological Sciences : An Official Journal of the Society of Toxicology. 121: 191-206
Boitano S, Flynn AN, Sherwood CL, et al. (2011) Alternaria alternata serine proteases induce lung inflammation and airway epithelial cell activation via PAR2. American Journal of Physiology. Lung Cellular and Molecular Physiology. 300: L605-14
Daines M, Flynn A, Sherwood C, et al. (2011) PAR-2 Activation by Alternaria alternata Proteases Induces Airway Epithelial Cell Activation and Lung Inflammation Journal of Allergy and Clinical Immunology. 127: AB59-AB59
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