Jacob Gorman, Ph.D.

2014 Immunology University of Iowa, Iowa City, IA 
Immunology, Cell Biology, Oncology
"Jacob Gorman"


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John D. Colgan grad student 2014 University of Iowa
 (Regulation of T cell responses by the surface receptor Tim-3.)
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Liu Y, Pagacz J, Wolfgeher DJ, et al. (2023) Senescent cancer cell vaccines induce cytotoxic T cell responses targeting primary tumors and disseminated tumor cells. Journal For Immunotherapy of Cancer. 11
Chen JL, Barr JY, Zuk JJ, et al. (2021) Reciprocal SH2-SH3 Domain Contacts between ITK Molecules Limit T Cell Receptor Signaling in Th2-type CD4 T Cells. Immunological Investigations. 1-18
Gorman JV, Colgan JD. (2018) Acute Stimulation Generates Tim-3-expressing Th1-type CD4 T Cells That Persist In Vivo and Show Enhanced Effector Function. Immunology
Phong BL, Avery L, Sumpter TL, et al. (2015) Tim-3 enhances FcεRI-proximal signaling to modulate mast cell activation. The Journal of Experimental Medicine
Thakar NY, Ovchinnikov DA, Hastie ML, et al. (2015) TRAF2 recruitment via T61 in CD30 drives NFκB activation and enhances hESC survival and proliferation. Molecular Biology of the Cell. 26: 993-1006
Gorman JV, Colgan JD. (2014) Response to Comment on "Tim-3 directly enhances CD8 T cell responses to acute Listeria monocytogenes infection". Journal of Immunology (Baltimore, Md. : 1950). 193: 467-8
Gorman JV, Colgan JD. (2014) Regulation of T cell responses by the receptor molecule Tim-3. Immunologic Research. 59: 56-65
Gorman JV, Starbeck-Miller G, Pham NL, et al. (2014) Tim-3 directly enhances CD8 T cell responses to acute Listeria monocytogenes infection. Journal of Immunology (Baltimore, Md. : 1950). 192: 3133-42
Chiba S, Baghdadi M, Akiba H, et al. (2012) Tumor-infiltrating DCs suppress nucleic acid-mediated innate immune responses through interactions between the receptor TIM-3 and the alarmin HMGB1. Nature Immunology. 13: 832-42
Curtiss ML, Gorman JV, Businga TR, et al. (2012) Tim-1 regulates Th2 responses in an airway hypersensitivity model. European Journal of Immunology. 42: 651-61
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