Kali Janes, Ph.D.

Affiliations: 
2013 Pharmacological and Physiological Science Saint Louis University, St. Louis, MO, United States 
Area:
Pharmacology, Physiology Biology, Neuroscience Biology
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"Kali Janes"

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Daniela Salvemini grad student 2013 Saint Louis University
 (A3 adenosine receptor agonist as novel therapeutic agents to prevent and reverse chemotherapy-induced neuropathic pain.)
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Publications

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Stockstill K, Doyle TM, Yan X, et al. (2018) Dysregulation of sphingolipid metabolism contributes to bortezomib-induced neuropathic pain. The Journal of Experimental Medicine
Wahlman C, Doyle TM, Little JW, et al. (2018) Chemotherapy-induced pain is promoted by enhanced spinal adenosine kinase levels via astrocyte-dependent mechanisms. Pain
Janes K, Symons-Liguori AM, Jacobson KA, et al. (2016) Identification of A3 adenosine receptor agonists as novel non-narcotic analgesics. British Journal of Pharmacology
Little JW, Ford A, Symons-Liguori AM, et al. (2015) Endogenous adenosine A3 receptor activation selectively alleviates persistent pain states. Brain : a Journal of Neurology. 138: 28-35
Janes K, Wahlman C, Little JW, et al. (2015) Spinal neuroimmune activation is independent of T-cell infiltration and attenuated by A3 adenosine receptor agonists in a model of oxaliplatin-induced peripheral neuropathy. Brain, Behavior, and Immunity. 44: 91-9
Janes K, Esposito E, Doyle T, et al. (2014) A3 adenosine receptor agonist prevents the development of paclitaxel-induced neuropathic pain by modulating spinal glial-restricted redox-dependent signaling pathways. Pain. 155: 2560-7
Janes K, Little JW, Li C, et al. (2014) The development and maintenance of paclitaxel-induced neuropathic pain require activation of the sphingosine 1-phosphate receptor subtype 1. The Journal of Biological Chemistry. 289: 21082-97
Janes K, Doyle T, Bryant L, et al. (2013) Bioenergetic deficits in peripheral nerve sensory axons during chemotherapy-induced neuropathic pain resulting from peroxynitrite-mediated post-translational nitration of mitochondrial superoxide dismutase. Pain. 154: 2432-40
Chen Z, Janes K, Chen C, et al. (2012) Controlling murine and rat chronic pain through A3 adenosine receptor activation. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 26: 1855-65
Janes K, Neumann WL, Salvemini D. (2012) Anti-superoxide and anti-peroxynitrite strategies in pain suppression. Biochimica Et Biophysica Acta. 1822: 815-21
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