Adam J. Dupuy

Anatomy & Cell Biology University of Iowa, Iowa City, IA 
Cell Biology, Molecular Biology, Genetics
"Adam Dupuy"
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Schillo JL, Feddersen CR, Peplinski RM, et al. (2024) Single-cell genomics analysis reveals complex genetic interactions in an model of acquired BRAF inhibitor resistance. Nar Cancer. 6: zcad061
Zhu EY, Schillo JL, Murray SD, et al. (2023) Understanding cancer drug resistance with functional genomic screens: Application to MAPK inhibition in cutaneous melanoma. Iscience. 26: 107805
Zhu EY, Riordan JD, Vanneste M, et al. (2022) SRC-RAC1 signaling drives drug resistance to BRAF inhibition in de-differentiated cutaneous melanomas. Npj Precision Oncology. 6: 74
Li Y, Zhou W, Meng X, et al. (2022) Utilizing an Endogenous Progesterone Receptor Reporter Gene for Drug Screening and Mechanistic Study in Endometrial Cancer. Cancers. 14
Sun F, Cheng Y, Riordan JD, et al. (2021) WDR26 and MTF2 are therapeutic targets in multiple myeloma. Journal of Hematology & Oncology. 14: 203
Schachter NF, Adams JR, Skowron P, et al. (2021) Single allele loss-of-function mutations select and sculpt conditional cooperative networks in breast cancer. Nature Communications. 12: 5238
Rogers LM, Wang Z, Mott SL, et al. (2020) A genetic screen to identify gain- and loss-of-function modifications that enhance T-cell infiltration into tumors. Cancer Immunology Research
Vanneste M, Feddersen CR, Varzavand A, et al. (2020) Functional Genomic Screening Independently Identifies CUL3 as a Mediator of Vemurafenib Resistance via Src-Rac1 Signaling Axis. Frontiers in Oncology. 10: 442
Rogers LM, Dupuy AJ, Weiner GJ. (2020) Abstract A51: Rationally improving T cell-mediated cancer immunotherapies using Sleeping Beauty mutagenesis to identify novel therapeutic targets Cancer Immunology Research. 8
Tompkins SC, Sheldon RD, Rauckhorst AJ, et al. (2019) Disrupting Mitochondrial Pyruvate Uptake Directs Glutamine into the TCA Cycle away from Glutathione Synthesis and Impairs Hepatocellular Tumorigenesis. Cell Reports. 28: 2608-2619.e6
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